A curated, citation-backed dataset of anesthetic and perioperative PK/PD model parameters featuring machine-enforced applicability envelopes, forward simulation, model-divergence visualization, and automated exports to standard pharmacometric formats like NONMEM, SBML, and Pumas.
simulation systems-biology open-science dataset tiva pharmacometrics pharmacokinetics clinical-research mathematical-biology sbml nonmem anesthesia pharmacodynamics quantitative-pharmacology nlmixr2 pk-pd target-controlled-infusion pumas-julia propofol remifentanil
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Updated
Jun 23, 2026 - Python