gabaergic-neurons

Here are 2 public repositories matching this topic...

Harkany-Lab / Zupancic_2023

This repository enables the reproducible analysis of an important developmental neuroscience dataset on hypothalamus neuron differentiation. It performs quality control, clustering, trajectory analysis, and identification of marker genes to characterize the differentiation trajectories of glutamatergic and GABAergic Onecut3+ neuronal subtypes.

transcription-factors cell-migration dopamine cytoskeleton trh single-cell-rna-sequencing glutamate thyrotropin-releasing-hormone hypothalamus-development neuronal-differentiation glutamatergic-neurons gabaergic-neurons onecut3 neuron-maturation neuritogenesis

Updated Aug 18, 2023
R

Qasim-Hussain-Code / alzheimer_cellular_vulnerability_sst_neurons_snRNA

Star

Single-nucleus transcriptomic profiling of cortical SST+ GABAergic interneurons in Alzheimer's disease to resolve selective metabolic vulnerability, modeling the pathogenic collapse of the PPARGC1A mitochondrial biogenesis regulon against SATB1-mediated cell-identity homeostasis.

differential-expression pathway-enrichment-analysis neurodegeneration gene-regulatory-networks gabaergic-neurons single-nucleus-rna-seq somatostatin-interneurons alzheimers-pathology selective-vulnerability mitochondrial-biogenesis ppargc1a-regulon satb1-chromatin transcriptional-collapse cortical-microcircuitry bioenergetic-failure snrna-seq-pipeline hypergeometric-ora regulon-activity-scoring

Updated Jun 25, 2026
Python

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