Carrick Therapeutics is a clinical-stage biopharmaceutical company headquartered in Boston, Massachusetts, developing novel oncology therapies aimed at improving outcomes for patients with aggressive and treatment-resistant cancers.
Relay Therapeutics is a Cambridge, Massachusetts clinical-stage precision medicines company (NASDAQ: RLAY) using protein motion to drug historically intractable oncology and genetic-disease targets.
Solu Therapeutics is a clinical-stage biotechnology company headquartered in Boston, Massachusetts, pioneering a novel class of antibody therapeutics that unlock cell-surface targets by combining small molecules with effector antibodies through proprietary linker technology.
Pathios Therapeutics is a clinical-stage oncology and immunology drug discovery and development company based in Oxfordshire, United Kingdom, founded in 2017. The company develops small-molecule inhibitors of the pH-sensing G protein-coupled receptor GPR65 to counteract the immunosuppressive tumor microenvironment; its lead asset PTT-4256 is a…
Engrail Therapeutics is a clinical-stage biopharmaceutical company founded in 2019 and focused on precision neuroscience. The company develops innovative, precision-targeted small-molecule therapeutics aimed at the molecular mechanisms and neural circuits underlying nervous system disorders, combining internal discovery with strategic…
Semnur Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company developing non-opioid pain-management therapies. Its lead program, SP-102 (SEMDEXA), is a novel, non-opioid, preservative-free and particulate-free injectable corticosteroid gel formulation intended to treat moderate-to-severe chronic radicular pain (sciatica).
ArriVent BioPharma is a clinical-stage biopharmaceutical company focused on the identification, development, and commercialization of differentiated medicines to address the unmet medical needs of patients with difficult-to-treat diseases, beginning with cancers.
Vima Therapeutics is a clinical-stage biotechnology company developing novel oral therapies for movement disorders, with a focus on the underlying biology of dystonia and Parkinson's disease.
Rallybio Corporation (NASDAQ RLYB) is a clinical-stage biotechnology company headquartered in New Haven, Connecticut, founded in 2018, developing and commercializing life-transforming therapies for patients with severe and rare diseases.
Chimerix, Inc. was a biopharmaceutical company headquartered in Durham, North Carolina, focused on developing medicines for serious and life-threatening diseases. It is best known for brincidofovir (TEMBEXA), an antiviral approved by the U.S.
Zenasbio — Zenas BioPharma is a global clinical-stage biopharmaceutical company focused on developing and delivering transformative treatments for patients with autoimmune and rare diseases. Its lead candidates are obexelimab, a bifunctional monoclonal antibody that inhibits B-cell activity without depleting B cells, and orelabrutinib, an oral…
Basking Biosciences is a clinical-stage biopharmaceutical company in Research Triangle, North Carolina (with operations in Mitchelton, Queensland, Australia) developing novel therapies for life-threatening blood clots.
Tenaya Therapeutics is a clinical-stage biotechnology company headquartered in South San Francisco, California, focused on discovering, designing, developing, and delivering potentially curative gene therapies and precision medicines that address the underlying drivers of heart disease.
Areteia Therapeutics was a clinical-stage biotechnology company, formerly based in Chapel Hill, North Carolina, operating in the life-sciences sector. As of the July 2026 enrichment pass the company is no longer operating: areteiatx.com serves only a closure notice directing asset and general inquiries to contact addresses, and the company…
Trishula Therapeutics is a privately held, clinical-stage immuno-oncology company developing cancer immunotherapies that target immune-evasion mechanisms in the tumor microenvironment.
Escient Pharmaceuticals is a San Diego, California clinical-stage biopharmaceutical company developing first-in-class, oral small-molecule therapeutics targeting Mas-related G protein-coupled receptors (MRGPRs) along the neurosensory-inflammatory axis.
Alpha-9 Oncology is a clinical-stage radiopharmaceutical company that spun out of the University of British Columbia and BC Cancer in 2019 to develop a portfolio of targeted cancer therapies.
Braveheart Bio is a late clinical-stage biopharmaceutical company developing novel therapeutics for hypertrophic cardiomyopathy (HCM) and related cardiac conditions. Its lead candidate, BHB-1893, is a selective cardiac myosin inhibitor (licensed as HRS-1893 from Hengrui Pharma) designed to reduce excessive heart-muscle contraction and improve…
kechowpharma — Kechow Pharma (Shanghai Kezhou Pharmaceutical Co., Ltd.) is a clinical-stage biopharmaceutical company founded in 2014 and headquartered in Shanghai's Zhangjiang High-Tech Park.
Aer Therapeutics is a clinical-stage biopharmaceutical company based in the Research Triangle Park / Raleigh area of North Carolina, developing novel treatments for muco-obstructive lung diseases such as COPD, asthma, cystic fibrosis, and non-CF bronchiectasis. A spinout from Dr.
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