Build somatic hypermutation (SHM) lineage trees from antibody repertoire sequencing data. Reconstruct clonal relationships between antibody sequences and visualize how B-cell receptor (BCR) clones diversify during somatic hypermutation and affinity maturation.
Select and rank the most promising antibody, peptide, or TCR candidates from a discovery campaign
Groups similar sequences (clonotypes or peptides) into clusters based on similarity using MMseqs2.
TenSixty Bio is an oncology-focused biotechnology company based in Cambridge, Massachusetts, working to revolutionize the treatment of cancer. The company combines biology, machine learning, and high-throughput technologies to build an atlas of antibody targets on the surface of cancer cells, discover novel cancer targets, and develop improved…
Infinimmune is a biotechnology company that discovers and engineers human-derived antibody therapeutics. Its Complete Human Sequencing and Anthrobody library-on-B-cell platform surface rare antibodies that evolution has already proven in people, and its GLIMPSE antibody language model characterizes and optimizes candidates in silico for clinical…
AbCellera (NASDAQ: ABCL) is a Vancouver-based antibody discovery and development company that integrates biology, computation, and engineering to develop antibody-based medicines. Its technology platform combines high-throughput single-cell antibody screening, GPCR and ion-channel capabilities, bispecifics, antibody-drug conjugates…
Align amplicon sequencing reads against your own reference construct instead of a germline database. Used for synthetic antibody and TCR libraries where diversity is engineered into defined regions of a known scaffold, and reports per-sample clonotypes with full alignment QC.
Adimab is a private biotechnology company founded in 2007, headquartered in Lebanon, New Hampshire, with a west coast office in Mountain View, California. It operates a proprietary yeast-based antibody discovery and engineering platform that combines fully human synthetic and immune libraries to generate specific, stable and developable IgGs…
Alloy Therapeutics is a biotechnology ecosystem company operating as a Product Development Organization that partners across discovery, preclinical, and clinical development. It combines proprietary AI/ML, real-world data, and tech-enabled scientific services across multiple therapeutic modalities, including monoclonal and bispecific antibodies…
Cradle is a Dutch–Swiss biotechnology software company founded in 2021 with headquarters in Amsterdam and an office in Zurich, building an AI-powered protein engineering platform for industrial biotech and biopharma R&D teams.
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