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tbAnnotator

A programm complex for annotating mycobacterium tuberculosis SNPs with information about drug resistance. It also performes scoring of SNPs not found in provided databases

Developed by avkitex, phill.gusev, pankevich-ev on Genehack-2

Requirenments

apt-get install python2.7, python-pip
pip install Cheetah

RUN

python tbAnnotator.py patient.vcf [ -gff annotation_gff -ddb dream_TB_database.db -tdb tbvar_database.db -oj output.json ]

output.json will contain final output information whick can be visualized with in html.

python htmlReportRegenerator.py -inj output.json -htmlrep report.html

report.html will contain sorted table with all drugs colored according to predicted drug resistance and a table with all snps and all information about them.

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A programm complex for annotating mycobacterium tuberculosis SNPs with information about drug resistance. It also performes scoring of SNPs not found in provided databases.

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