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ecMTM

The process for ecMTM model construction.

Installation

1.create ECMpy environment using conda:

$ conda create -n ECMpy python=3.6.5

2.install related packages using pip:

$ conda activate ECMpy
$ pip install cobra==0.13.3
$ pip install plotly
$ pip install -U kaleido
$ pip install nbformat
$ pip install requests
$ pip install Bio
$ pip install scipy
$ pip install ipykernel

01_Constuct eciyw1475_TurNup.ipynb

Construction of ecMTM.

02_CDF_kcat_and_mw.ipynb

Cumulative distribution of kcat and molecular weights. 03_FVA.ipynb

Comparative flux variability analysis.

04_PhPP_analysis.ipynb

Phenotype phase plane (PhPP) analysis.

05_trade-off.ipynb

Overflow metabolism simulation. 06_Substrte cascade utilization.ipynb

Substrte cascade utilization prediction. 07_metabolic_engineering_targets.ipynb

Metabolic engineering targets prediction.

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