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t-cell-epitope

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Bias-controlled evaluation protocol and pipeline for neoantigen immunogenicity prediction: matched HLA-only and peptide-only null controls, shortcut-dependence diagnostics, and a no-override acceptance gate.

  • Updated Oct 11, 2026
  • Python

Chapter 6 of Machine Learning for Biology. Sequence-only immunogenicity prediction on 1,200 HLA-A*02:01 IEDB binders, cluster-split and pre-registered. Network 0.610 AUPRC, binding-only baseline 0.591, chance 0.485.

  • Updated Sep 20, 2026
  • Python

An ML-based immunogenicity predictor for T-cell epitopes of Mycobacterium Tuberculosis. It is purely based on amino acid sequences of epitope. Used Physicochemical descriptors and Amino Acid composition to make this proteomic data ML ready.

  • Updated Aug 10, 2026
  • Jupyter Notebook

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