Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation
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Updated
Jul 20, 2025 - Jupyter Notebook
Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation
A high-fidelity Systems Immunology Interaction Engine using Agent-Based Modeling (Mesa 2.3.0) to simulate Tumor Microenvironment (TME) dynamics, metabolic clearance, and autonomous AI-driven clinical interventions.
Theoretical analysis code for antigen encoding from cytokine dynamics.
Analysis notebooks supporting a single-cell study of metallothioneins in atopic dermatitis.
Source code for the At-Risk RA work
scATAC-seq pipeline mapping mucosal immunity and host-microbe crosstalk. Profiles physical chromatin accessibility of Trm cells (Itgae/CD103) and Secretory IgA Plasma cells (Igj) to decode intestinal defense mechanisms.
An integrated computational pipeline for CRISPR-Cas13a (SHERLOCK) malaria diagnostics and trans-kingdom neuro-immune mapping, linking PfK13-driven pathogen detection to microglial homeostatic (CX3CR1/Iba1) set-points and Gut-Brain Axis (GBA) dysregulation.
Reproducible Systems Immunology Framework for Modeling CD40–TRAF6 Signaling Dynamics and CRISPR Synergy
Public profile for Dr Andres Vallejo Pulido
Systems immunology workflow for reconstructing cell–cell communication networks in lupus nephritis using CellChat and single-cell RNA sequencing.
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