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snp-harmonization

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Qasim-Hussain-Code / neurodegenerative_cross_tissue_twas

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End-to-end TWAS pipeline for Alzheimer's disease integrating Kunkle et al. (2019) GWAS summary statistics with GTEx v8 MASHR brain eQTL models to identify causal genes via cross-tissue omnibus regression and functional pathway over-representation analysis.

gwas gene-expression gtex alzheimers-disease eqtl summary-statistics neurogenomics twas genome-wide-association-study brain-tissue neurodegenerative-disease transcriptome-wide-association-study spredixcan smultixcan metaxcan cross-tissue-analysis mashr predictdb snp-harmonization
  • Updated Jun 9, 2026
  • Python

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