lincs-l1000

Single-cell transcriptomic analysis and LINCS-based computational drug repurposing in HER2-positive breast cancer.

End‑to‑end pipeline for generating context‑aware drug embeddings from LINCS L1000 using RNA‑seq preprocessing, STRING PPI networks, and GNNs, with UMAP visualisation and drug‑class neighbourhood analysis.

[Donor] Drug-Response via LINCS L1000 + scRNA-seq | 药物响应

PERSIST (PERsister-State In-Silico Targeting): residual-state modelling of single-cell drug response for combination therapy prediction in EGFR-mutant NSCLC and TNBC