A Python library for discovery of genotype-phenotype associations
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Updated
Mar 24, 2026 - Python
A Python library for discovery of genotype-phenotype associations
nf-core/deepmutscan is a reproducible, scalable, and community-curated pipeline for analyzing deep mutational scanning (DMS) data using shotgun DNA sequencing.
Genotype–phenotype association analysis of carbapenem resistance in Klebsiella pneumoniae using BV-BRC AMR data (R, statistical genomics).
Reference implementation of the Intra-Organismal Data Symbiosis (IODS) framework. Multimodal biological translation: DNA, phenotype, environment.
Deterministic, interpretable genome→phenotype decoder: calls antibiotic/antiviral/antifungal resistance from DNA + names the exact genes/mutations driving each call. Spans bacteria, M. tuberculosis, fungi, HIV-1 & SARS-CoV-2 — independently validated on FREE measured wet-lab labels (EBI AMR Portal, Stanford HIVDB). Not a clinical tool.
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