A reproducible bioinformatics case study of the hemoglobin beta E6V mutation, connecting FASTA parsing, pairwise alignment, BLOSUM scoring, BLAST evidence, and PDB-based structural contacts to explain how one amino-acid change becomes biologically meaningful. It contains scripts, figures, reports, and clear limits on what the analysis can clai
bioinformatics reproducible-research pdb protein-structure blast case-study sequence-alignment structural-bioinformatics sickle-cell protein-sequence-analysis hemoglobin blosum62 e6v-mutation
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Updated
Mar 14, 2026 - Python