Comprehensive design of CRISPR gRNAs for nucleases and base editors
On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs
a guideRNA database generation tool
Tutorials for the crisprVerse
Collection of R packages that work in harmony for CRISPR gRNA design
CRISPR, faster, better – The Crackling method for whole-genome target detection
Variant- and Haplotype-aware CRISPR guide design toolkit
A Snakemake workflow for the design of small guide RNAs (sgRNAs) for CRISPR applications.
A guideRNA design tool for the modern era.
Visualization of CRISPR guide RNAs (gRNAs)
Base functions and classes for CRISPR gRNA design
CRISPR Guide RNA Designer
Useful human and mouse data for the crisprVerse ecosystem
Bowtie-based alignment of CRISPR gRNA spacer sequences
Creates a construct developed by the Niles Lab at MIT, designed to deliver a 3' UTR post-transcriptional regulatory element payload to a specific given gene in Plasmodium falciparum.
BWA-based alignment of CRISPR gRNA spacer sequences
Pre-trained models for the crisprScore package
Shiny interface for CRISPR gRNAs designed with the crisprVerse
Fork of Azimuth (Machine Learning-Based Predictive Modelling of CRISPR/Cas9 guide efficiency), updated to work with Python 3.10+
A Python-based CRISPR guide RNA analyzer that identifies SpCas9 target sites and ranks candidate guides using GC content, self-complementarity, homopolymer detection and restriction site screening.
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