Sepsis fluids and timing - dose-response meta-analysis

A living systematic review

(this meta-analysis is in the exploratory state; formal lit search has not been started)

Short url: http://openmetaanalysis.github.io/Sepsis-fluids_and_timing_-_dose-response_meta-analysis

Clinical summary: This meta-analysis suggests that the optimal dosing of fluids is:

• Pending

Methods overview:

(Under construction)

This repository is an openMetaAnalysis that combines methods of scoping, rapid, and living systematic reviews. This analysis updates one or more previously published review(s) below. A comparison of studies included in this review compared to prior reviews are in the table, reconciliation of trials included with prior meta-analyses/. Newer studies included are listed in the references below. Rationale for newer trials excluded may be listed at the end of the references.

• Methods for openMetaAnalysis
• Evidence search for this review (under construction)

Results::

(Under construction)

• Forest plots
• spreadsheets with source data
• R code

References:

Systematic review(s)

Most recent review at time of last revision of this repository

1. Ward MA, Kuttab HI, Badgett RG. The Effect of Early Fluid Resuscitation on Mortality in Sepsis: A Systematic Review and Meta-Analysis. Crit Care Med. 2025 Jul 10. doi: 10.1097/CCM.0000000000006769. Epub ahead of print. PMID: 40637496.

Randomized controlled trials or cohort studies

New trial(s) not included in the most recent review above

Pending

Trial(s) included in the review above

Pending

Trial(s) undergoing review

Pending

Trial(s) excluded - selected list of important trial(s)

Pending

Cited by

This repository is cited by:

1. WikiDoc contributors. Pending content page. WikiDoc. Nov 9, 2014. Available at: http://www.wikidoc.org/index.php/This_topic. Accessed November 9, 2014.

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