AIMEE (Animal IsomiR and MiRNA Expression Explorer) hosts miRNA and isomiR expression data across 461 equine small RNA-seq samples, spanning 61 tissue types. The samples were sourced from 12 American Quarter horses, 4 FAANG Thoroughbreds, and 158 samples from public data repositories. All samples were processed using the pipeline FARmiR (https://github.com/jonahcullen/FARmiR).
AIMEE is a Shiny application built using the golem framework. The app enables users to
- Filter and compare expression by tissue, breed, sex, and data source
- Explore canonical and non-canoncial miRNA expression patterns
- Evaluate isomiRs across different processing types
- Visualize top miRNAs per tissue and investigate overlap
- Download expression tables plots
Detailed descriptions and usage guidance are provided within the app!
You can install the development version of AIMEE like so:
# install devtools if you have not already
install.packages("devtools")
# install package from github
devtools::install_github("jonahcullen/AIMEE")
To open the AIMEE browser:
library(AIMEE)
run_app()
## basic example code
Please note that the AIMEE project is released with a Contributor Code of Conduct. By contributing to this project, you agree to abide by its terms.