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hdbp/README.md

Hugo Pinto

Staff Scientist at the Albert Einstein College of Medicine, specialising in chromatin biology and epigenetics.

PhD in Transcription Regulation (Italy) → Postdoctoral fellow in Stem Cell Biology at Burke Medical Research Institute / Weill Cornell Medicine → Staff Scientist at Albert Einstein College of Medicine.

My research focuses on H1 linker histones and their role in transcriptional and epigenetic regulation, using mouse embryonic stem cells (mESCs) as a model system as well as other mouse and human cell lines. I combine wet-lab approaches (ChIP-seq, CUT&Tag, PRO-seq, ATAC-seq, Hi-C) with computational analysis in R/Bioconductor.

Research interests

  • Histone H1 biology and chromatin compaction
  • Transcriptional pause-release and elongation dynamics
  • Multi-omics integration (RNA-seq × ATAC-seq × ChIP-seq)
  • Epigenetic regulation in development and disease

Skills

R Bioconductor DESeq2 csaw edgeR ggplot2 bash SLURM Linux
ChIP-seq · ATAC-seq · PRO-seq · CUT&Tag · Hi-C · RNA-seq · CRISPR/Cas9

Links

ORCID Einstein LinkedIn

Popular repositories Loading

  1. omics omics Public

    Reproducible R analysis pipeline integrating RNA-seq, ATAC-seq, and ChIP-seq to characterise the epigenetic consequences of H1 histone loss in immune cells (cTKO vs WT). GEO Accession GSE141187

    R

  2. dotfiles dotfiles Public

    backup of config files

    Shell

  3. hdbp hdbp Public