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Lung aging analysis

License: MIT DOI

Table of contents generated with markdown-toc

Getting Started

1 Introduction

This repository includes jupyter notebooks for reproducing the analysis results presented in the manuscript.

Alt text

2 Installation

We provide conda environment files to install all necessary packages for users interested in running the analyses in the manuscript. Clone this repository and under the root folder of the repository, you can find lung_aging.yml and HLCA_mapping_env.yml, where the former is for running most of the analyses and reproducing figures in the manuscript and the latter is for running cell type label transfer between query dataset and the HLCA dataset. You may install this two environments by

conda env create -f lung_aging.yml
conda env create -f HLCA_mapping_env.yml

You will then be able to access all required packages by loading these environments in your jupyter notebook.

3 Datasets

Run script step0_download_data_and_prepare.py to download all datasets analyzed in the manuscript. The datasets will be downloaded into the folder data/ under the root folder of this repository.

4 Analyses

The analyses can be performed in the sequential order specified by the prefix "stepX_" of each script file.

Contact

Contact us if you have any questions:
Qi (Alex) Song: qisong@andrew.cmu.edu; sqsq3178@gmail.com
Ziv Bar-Joseph: zivbj@andrew.cmu.edu

Citation

Comming soon!

Copyright

©2021 Qi Song, Ziv Bar-Joseph. Systems Biology Group at Carnegie Mellon University. All rights reserved.

About

This repository demonstrates analyses presented in the manuscript

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