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Sivasan/README.md

Hi, I'm Sivasankar Palaniappan πŸ‘‹

Scientist | Marine Microbiology | Environmental Biotechnology | Microbial Genomics | Bioinformatics | AI-assisted Scientific Research

I am a researcher with 13+ years of experience spanning marine microbiology, environmental biotechnology, microbial ecology, genomics, and bioinformatics. My work combines laboratory experimentation with computational biology to understand microbial diversity, discover novel microorganisms, and develop reproducible scientific workflows.

I am particularly interested in integrating artificial intelligence, large language models, and bioinformatics to accelerate scientific discovery.


πŸ”¬ Research Interests

  • Marine Microbiology
  • Environmental Microbiology
  • Environmental Biotechnology
  • Microbial Ecology
  • Microbial Genomics
  • Comparative Genomics
  • Bacterial Taxonomy & Systematics
  • Shotgun Metagenomics
  • Metagenome-Assembled Genomes (MAGs)
  • Methanotroph Ecology
  • Nanopore Sequencing
  • AI-assisted Scientific Research

πŸš€ Current Research

  • Characterization of novel bacterial species
  • Genome-based bacterial taxonomy
  • Comparative genomic analysis
  • Nanopore sequencing workflows
  • Functional metagenomics
  • Microbial community analysis
  • AI-assisted scientific writing
  • Reproducible computational biology workflows

πŸ’» Computational Skills

Programming

  • Python
  • Bash
  • Linux Shell

Bioinformatics

  • BLAST
  • Minimap2
  • Flye
  • Medaka
  • CheckM
  • BUSCO
  • GTDB-Tk
  • FastANI
  • IQ-TREE
  • FastTree
  • Prokka
  • Bakta
  • seqkit

Computing

  • Linux
  • High Performance Computing (HPC)
  • AWS Cloud

πŸ§ͺ Research Experience

My research has involved

  • Marine microbial ecology
  • Mangrove microbial communities
  • Methanotroph enrichment and cultivation
  • Environmental DNA analysis
  • Whole-genome sequencing
  • Comparative genomics
  • Genome annotation
  • Environmental monitoring
  • Environmental impact assessment (EIA)
  • Bioinformatics workflow development
  • AI-assisted scientific analysis

πŸ“‚ Featured Projects

PUT101 β€” Novel Bacterial Species Characterization

Comprehensive genome-based taxonomic characterization of a novel bacterial isolate using comparative genomics, phylogenomics, ANI, dDDH, genome annotation, and publication-ready analyses.


Nanopore Bioinformatics Workflows

Analysis pipelines for Oxford Nanopore sequencing including assembly, polishing, annotation, and downstream comparative analyses.


Environmental Metagenomics

Computational workflows for microbial community analysis, metagenome assembly, genome reconstruction, and functional annotation.


AI-assisted Scientific Workflows

Applications of large language models to scientific writing, computational biology, reproducible research, literature synthesis, and bioinformatics.


🌱 Currently Learning

  • Advanced Python for bioinformatics
  • Workflow automation
  • Cloud-native bioinformatics
  • Scalable genomics pipelines
  • AI agents for scientific research

🀝 Collaboration Interests

I welcome collaborations in

  • Marine microbiology
  • Environmental biotechnology
  • Microbial genomics
  • Comparative genomics
  • Bacterial taxonomy
  • Environmental metagenomics
  • Bioinformatics
  • AI for scientific research

πŸ“« Connect

Thank you for visiting my profile!

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