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ShilohCadere/README.md

Shiloh Cadere

Bioinformatics Analyst | Genomics QC & Data Validation | Python • SQL • Nextflow

Bioinformatics analyst focused on genomics QC, analytical review, reproducible workflow development, and laboratory informatics. My work combines regulated laboratory experience with bioinformatics software that supports sequencing quality assessment, workflow automation, and data validation.

Portfolio Overview

Clinical NGS Review (Python)

Analyst-focused NGS QC review workflow applying configurable QC rules, run-level analysis, and structured reporting using simulated sequencing data.

→ QC interpretation, analytical reasoning, and production-style software architecture

Clinical NGS Workflow (Nextflow & Docker)

Reproducible Nextflow DSL2 workflow processing paired-end FASTQ data through quality control, alignment, variant calling, and reporting.

→ Reproducible sequencing pipelines and workflow orchestration

Barcode Crossover Analysis (Nextflow & Python)

Reproducible Nextflow workflow quantifying barcode crossover in Oxford Nanopore sequencing data through alignment-based analysis and automated reporting.

→ Sequencing analysis, workflow engineering, and biological interpretation

Laboratory LIMS Database (Oracle SQL)

Requirements-driven laboratory information management system supporting sample traceability, workflow tracking, audit logging, and structured data access.

→ Relational database design and laboratory informatics

Genomic Toolkit (Python CLI)

Python toolkit supporting FASTA parsing, sequence analysis, protein translation, and command-line bioinformatics workflows.

→ Reusable bioinformatics software utilities

Current Interests

  • Genomics QC and analytical review
  • Reproducible bioinformatics workflows
  • Pipeline development with Nextflow
  • Laboratory informatics and data validation
  • Clinical and research sequencing analysis

Contact

Open to bioinformatics, clinical genomics, and laboratory informatics opportunities focused on sequencing analysis, workflow development, and quality-driven data interpretation.

Pinned Loading

  1. clinical-ngs-review clinical-ngs-review Public

    Analyst-focused NGS QC review workflow applying configurable QC rules, run-level analysis, and structured reporting using simulated sequencing data.

    Python

  2. clinical-ngs-workflow clinical-ngs-workflow Public

    Reproducible Nextflow workflow for FASTQ QC, alignment, variant calling, and reporting.

    Nextflow

  3. ont-barcode-crossover-analysis ont-barcode-crossover-analysis Public

    Reproducible Nextflow workflow quantifying barcode crossover in Oxford Nanopore sequencing data through alignment-based analysis.

    Python

  4. laboratory-lims-database laboratory-lims-database Public

    Requirements-driven Oracle SQL LIMS modeling sample traceability, workflow tracking, audit logging, and laboratory data management.