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147 changes: 143 additions & 4 deletions docs/itk_lib.rst
Original file line number Diff line number Diff line change
Expand Up @@ -3,16 +3,23 @@
ITK
===

`ITK`_ is a widely-used library for volumetric image processing. In order to
use ITK with highdicom, the ``itk`` python package must be installed separately.
Version 5.4.0 or later is required.
`ITK`_ is a widely-used library for volumetric image processing. While many
simple processing operations can be performed within highdicom itself, ITK
provides a much larger set of tools and many existing image processing
pipelines are built in ITK. By integrating highdicom with ITK, you can
therefore benefit from both ITK's large set of processing features and
highdicom's support for DICOM reading and writing with minimal "glue code". In
particular, correctly transferring spatial metadata between highdicom and ITK
representations is straightforwardly handled for you. In order to use ITK with
highdicom, the ``itk`` python package must be installed separately. Version
5.4.0 or later is required.

.. _itk_vol:

Volume Conversions
------------------

Highdicom supports conversions with the ``itk.Image`` class through the
Highdicom supports conversions to/from the ``itk.Image`` class through the
:meth:`highdicom.Volume.to_itk` and :meth:`highdicom.Volume.from_itk` methods.
Like highdicom, ITK uses the "LPS" convention. However, when converting to and
from NumPy arrays, ITK reverses the order of dimensions. This permutation is
Expand Down Expand Up @@ -42,4 +49,136 @@ Creating a volume from an ITK Image:
vol = hd.Volume.from_itk(itk_image)


Use Cases
---------

**Load a DICOM Segmentation into ITK:**

This allows you to work primarily in ITK, while still benefitting from
highdicom's full feature set for reading segmentations, such as correctly
combining multiple segments, filtering segments, filling in missing slices,
lazily retrieving frames, etc. This behavior is not limited to Segmentations,
and would work equally well with any DICOM image the :class:`highdicom.Image`
class supports. The resulting ITK image will have its spatial affine matrix
correctly populated from the source DICOM file.

.. code-block:: python

import highdicom as hd

# Here we load in an example DICOM segmentation from the highdicom repo test
# data that contains two segments. Parameters of the get_volume() method
# control the volume that is extracted. For example, here we choose one of the
# two segments and cast to uint32 before converting to ITK
itk_image = (
hd.seg.segread("data/test_files/seg_image_ct_binary_overlap.dcm")
.get_volume(
segment_numbers=[2],
relabel=True,
combine_segments=True,
dtype='uint32',
)
.to_itk()
)

**Create a DICOM Segmentation from an ITK image:**

This allows you to build processing pipelines primarily in ITK, but then
benefit from highdicom's full versatile support for creating DICOM
segmentations, including support for multiple segmentation types, multiple
compression methods (transfer syntaxes) etc. The spatial metadata is correctly
carried throughout this whole snippet and stored in the segmentation without
requiring any user code.


.. code-block:: python

import itk
import highdicom as hd
from pydicom.sr.codedict import codes
from pydicom.uid import JPEGLSLossless


# An example CT file in highdicom test data repo
ct_file = "data/test_files/ct_image.dcm"

# Read the image file using itk
itk_image = itk.imread(ct_file, pixel_type=itk.SS)

# We do still need to load the source CT image file with highdicom (or
# pydicom) to get the metadata, but we can skip the pixel data
source_image = hd.imread(ct_file, lazy_frame_retrieval=True)


def itk_segmentation_method(image: itk.Image) -> itk.Image:
"""Toy example of a processing method built with ITK.

Here we just apply a simple intensity threshold at 300HU as an example.

"""
thresholder = itk.BinaryThresholdImageFilter[
type(image),
itk.Image[itk.UC, 3] # produce unsigned 8 bit output image
].New()
thresholder.SetInput(image)
thresholder.SetLowerThreshold(300)
thresholder.SetInsideValue(1)
thresholder.Update()
return thresholder.GetOutput()


# Run the ITK processing
seg_image = itk_segmentation_method(itk_image)

# Create a highdicom Volume from the ITK image to pass to the
# highdicom.Segmentation constructor
seg_volume = hd.Volume.from_itk(seg_image)

# In this case, the Volume has shape (128, 128, 1). highdicom.Segmentation
# stores volumes split into frames split down the first dimension, so to
# get the most sensible output we will transpose the volume. We could do
# this explicitly, or, more straightforwardly, just transpose to match to
# the orientation of the source image
seg_volume = seg_volume.match_orientation(source_image.get_volume_geometry())

# Now to start creating the segmentation. First we have to describe the segment.
# Here, we describe a bone segment produced by an automatic algorithm)
bone_description = hd.seg.SegmentDescription(
segment_number=1,
segment_label='Bone',
segmented_property_category=codes.SCT.AnatomicalStructure,
segmented_property_type=codes.SCT.Bone,
algorithm_type=hd.seg.SegmentAlgorithmTypeValues.AUTOMATIC,
algorithm_identification=hd.AlgorithmIdentificationSequence(
name='Thresholder 5000X',
version='v1.0',
family=codes.cid7162.MorphologicalOperations
)
)

# Now construct the DICOM Segmentation Image from the ITK segmentation mask.
# Highdicom will take the spatial information from the itk image (via the
# highdicom Volume) and compare it to the source image metadata to establish
# the spatial relationship between the segmentation mask and the source image
# automatically
seg = hd.seg.Segmentation(
source_images=[source_image],
pixel_array=seg_volume,
segmentation_type=hd.seg.SegmentationTypeValues.LABELMAP,
segment_descriptions=[bone_description],
series_instance_uid=hd.UID(),
series_number=1,
sop_instance_uid=hd.UID(),
instance_number=1,
manufacturer='Foo Corp.',
manufacturer_model_name='Bone Segmentation Algorithm',
software_versions='0.0.1',
device_serial_number='1234567890',
transfer_syntax_uid=JPEGLSLossless,
series_description='Bone Threshold Segmentation',
)

# Save output file
seg.save_as("bone_segmentation.dcm")

.. _`ITK`: https://itk.org/
142 changes: 139 additions & 3 deletions docs/sitk_lib.rst
Original file line number Diff line number Diff line change
Expand Up @@ -3,9 +3,16 @@
SimpleITK
=========

`SimpleITK`_ provides a simplified interface for the algorithms and data structures
of `ITK`_. In order to use ITK with highdicom, the ``SimpleITK`` python package must
be installed separately. Version 2.2.1 or later is required.
`SimpleITK`_ is a widely-used library for volumetric image processing. While
many simple processing operations can be performed within highdicom itself,
SimpleITK provides a much larger set of tools and many existing image
processing pipelines are built in SimpleITK. By integrating highdicom with
SimpleITK you can therefore benefit from both ITK's large set of processing
features and highdicom's support for DICOM reading and writing with minimal
"glue code". In particular, correctly transferring spatial metadata between
highdicom and SimpleITK representations is straightforwardly handled for you.
In order to use ITK with highdicom, the ``SimpleITK`` python package must be
installed separately. Version 2.2.1 or later is required.

.. _sitk_vol:

Expand Down Expand Up @@ -46,3 +53,132 @@ Creating a volume from a SimpleITK Image:

.. _`ITK`: https://itk.org/
.. _`SimpleITK`: https://simpleitk.org/


Use Cases
---------

**Load a DICOM Segmentation into SimpleITK:**

This allows you to work primarily in SimpleITK, while still benefitting from
highdicom's full feature set for reading segmentations, such as correctly
combining multiple segments, filtering segments, filling in missing slices,
lazily retrieving frames, etc. This behavior is not limited to Segmentations,
and would work equally well with any DICOM image the :class:`highdicom.Image`
class supports. The resulting SimpleITK image will have its spatial affine
matrix correctly populated from the source DICOM file.

.. code-block:: python

import highdicom as hd

# Here we load in an example DICOM segmentation from the highdicom repo test
# data that contains two segments. Parameters of the get_volume() method
# control the volume that is extracted. For example, here we choose one of the
# two segments and cast to uint32 before converting to ITK
sitk_image = (
hd.seg.segread("data/test_files/seg_image_ct_binary_overlap.dcm")
.get_volume(
segment_numbers=[2],
relabel=True,
combine_segments=True,
dtype='uint32',
)
.to_simpleitk()
)

**Create a DICOM Segmentation from a SimpleITK image:**

This allows you to build processing pipelines primarily in SimpleITK, but then
benefit from highdicom's full versatile support for creating DICOM
segmentations, including support for multiple segmentation types, multiple
compression methods (transfer syntaxes) etc. The spatial metadata is correctly
carried throughout this whole snippet and stored in the segmentation without
requiring any user code.


.. code-block:: python

import SimpleITK as sitk
import highdicom as hd
from pydicom.sr.codedict import codes
from pydicom.uid import JPEGLSLossless


# An example CT file in highdicom test data repo
ct_file = "data/test_files/ct_image.dcm"

# Read the image file using itk
sitk_image = sitk.ReadImage(ct_file, outputPixelType=sitk.sitkInt16)

# We do still need to load the source CT image file with highdicom (or
# pydicom) to get the metadata, but we can skip the pixel data
source_image = hd.imread(ct_file, lazy_frame_retrieval=True)


def sitk_segmentation_method(image: sitk.Image) -> sitk.Image:
"""Toy example of a processing method built with SimpleITK.

Here we just apply a simple intensity threshold at 300HU as an example.

"""
thresholder = sitk.BinaryThresholdImageFilter()
thresholder.SetLowerThreshold(300)
thresholder.SetUpperThreshold(10000)
thresholder.SetInsideValue(1)
return thresholder.Execute(image)


# Run the ITK processing
seg_image = sitk_segmentation_method(sitk_image)

# Create a highdicom Volume from the ITK image to pass to the
# highdicom.Segmentation constructor
seg_volume = hd.Volume.from_simpleitk(seg_image)

# In this case, the Volume has shape (128, 128, 1). highdicom.Segmentation
# stores volumes split into frames split down the first dimension, so to
# get the most sensible output we will transpose the volume. We could do
# this explicitly, or, more straightforwardly, just transpose to match to
# the orientation of the source image
seg_volume = seg_volume.match_orientation(source_image.get_volume_geometry())

# Now to start creating the segmentation. First we have to describe the segment
# Here, we describe a bone segment produced by an automatic algorithm)
bone_description = hd.seg.SegmentDescription(
segment_number=1,
segment_label='Bone',
segmented_property_category=codes.SCT.AnatomicalStructure,
segmented_property_type=codes.SCT.Bone,
algorithm_type=hd.seg.SegmentAlgorithmTypeValues.AUTOMATIC,
algorithm_identification=hd.AlgorithmIdentificationSequence(
name='Thresholder 5000X',
version='v1.0',
family=codes.cid7162.MorphologicalOperations
)
)

# Now construct the DICOM Segmentation Image from the ITK segmentation mask.
# Highdicom will take the spatial information from the itk image (via the
# highdicom Volume) and compare it to the source image metadata to establish
# the spatial relationship between the segmentation mask and the source image
# automatically
seg = hd.seg.Segmentation(
source_images=[source_image],
pixel_array=seg_volume,
segmentation_type=hd.seg.SegmentationTypeValues.LABELMAP,
segment_descriptions=[bone_description],
series_instance_uid=hd.UID(),
series_number=1,
sop_instance_uid=hd.UID(),
instance_number=1,
manufacturer='Foo Corp.',
manufacturer_model_name='Bone Segmentation Algorithm',
software_versions='0.0.1',
device_serial_number='1234567890',
transfer_syntax_uid=JPEGLSLossless,
series_description='Bone Threshold Segmentation',
)

# Save output file
seg.save_as("bone_segmentation.dcm")