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Johnston_et_al_2020

A repository for the code used for the analysis within the paper "A cellular stress response induced by the CRISPR/dCas9 activation system is not heritable through cell divisions."

Alignment.md details the alignment of our HEK293T data
DEG_Analysis.rmd details the differentially expressed gene analysis for HEK293T
DEG_SKOV3_Analysis.rmd details the DEG analysis for SKOV3 cells and the comparison to HEK293T cells.
Off-target_analysis.rmd details the how potential off-target effects of the activation system were assessed.

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A repository for the code used for the analysis within the paper "Transient side effects of CRISPR/Cas9-VP160 for gene activation"

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