Recommendation for library-free search?

[wyu]

I understand that DreamDIA supports only the search with spectral lib. Have you tried to use the predicted spectral library to allow for the libFree search?

A possibility is to take the predicted library from DIA-NN, similar to how the libFree search is implemented in DIA-NN. The predicted splib is in the proprietary "speclib", though there is enough docs to convert to SpectraST format I think.

Thanks!
Wen Yu