A curated list of fruit fly connectome projects: MaleCNS, FlyWire, brain simulations, embodied models, games, and research tools.
-
Updated
Sep 14, 2026
A curated list of fruit fly connectome projects: MaleCNS, FlyWire, brain simulations, embodied models, games, and research tools.
Experimental Drosophila-inspired camera-to-robot bridge. Working mock neural backend, optical flow, IMU feedback and UDP motor control. MaleCNS integration planned.
Embodied Drosophila: 138,639-neuron whole-brain connectome simulation (FlyWire v783) in a biomechanical body (NeuroMechFly v2 / MuJoCo). Vision, olfaction, gustation, flight, and emergent behaviors — all from the real connectome.
Neuro-Cybernetic Protocol: versioned canonical-JSON contract connecting neural simulators and neuromorphic controllers to robots, UAVs and analysis clients over Zenoh. Rust reference, independent TypeScript validator, Python/C/C++ bindings. v0.8.0 is the latest release; HEAD is a release-blocked 1.0 candidate.
A persistent spiking neural network that lives on your desktop — 1,260 neurons, STDP learning, neuromodulators, and an LLM speech layer.
Drosophila larva connectome (1,373 neurons, 22,400 synapses) drives a real-time MuJoCo physics body. Sensory input activates biologically accurate LIF neural circuits. Based on Winding et al., Science 2023. Built with Python, MuJoCo, and Qwen2.5 LLM.
A real-time simulation of a virtual creature controlled by a spiking neural network built on biologically accurate mechanisms. The creature navigates a 2D world, forages for food, avoids predators and poisons, and learns from experience through dopamine-modulated synaptic plasticity.
🧠 A biologically-accurate spiking neural network. Pure C99. No frameworks. No matrices. Neurons fire, learn, dream, and evolve. — Proprietary: Non-commercial use only.
An experimental, from-scratch Warhammer 40k Skitarii cyborg-brain emulator in Python. Each brain region's organic mass decides its processor: organic remnants run as LLM calls, excised regions as deterministic implants. The deliberately faithful, near-unreadable first take that the brain-emulation fork replaced.
BraindGo db — Brain simulation database → Robot driving engine, from C. elegans to humanoid
BFSimulator is a research project that simulates fetal brain cortical folding using a physics-based finite-element model (C++/deal.II). It pairs the solver with a modern PySide6 dashboard for setting parameters, running simulations, and visualizing the results.
A self-learning neuromorphic distributed brain. Free. Open. Ethical.
Virtual Brain Twin for Personalized Treatment of Psychiatric Disorders using Python and Brain Simulation.
Python bridge connecting BrainGo db to BAAIWorm 3D body simulation
Pure GDScript neural network implementation for Godot Engine with real-time topology visualization.
Connectome-scale SNN simulation energy benchmarks — software ceiling analysis for Drosophila whole-brain on GPU
Kick-the-buddy game where the buddy is a live 166,700-neuron fruit fly connectome
Fork of Jessie940611/BAAIWorm with BrainGo db integration — C. elegans brain-body-environment model
To associate your repository with the brain-simulation topic, visit your repo's landing page and select "manage topics."