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This means that the estimated coverage can be biased, as the zeros are not counted when calculating the mean/median coverage? samtools depth now offers an option (-a) to resolve this so it should be straightforward: samtools/samtools#374
This means that the estimated coverage can be biased, as the zeros are not counted when calculating the mean/median coverage?
samtools depthnow offers an option (-a) to resolve this so it should be straightforward:samtools/samtools#374