diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index f7861f0c564a..840b7caf4263 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -387,8 +387,8 @@ jobs:
             PATH: pyopenssl
           - DOWNSTREAM: twisted
             REPO: twisted/twisted
-            # Latest commit on the twisted trunk branch, as of Oct 18, 2026.
-            REF: be48511c722548ddd4670f4070e7910a321e8a97
+            # Latest commit on the twisted trunk branch, as of Oct 23, 2026.
+            REF: 44048df8c7581df6112016747bfe864e93ac0809
             PATH: twisted
           - DOWNSTREAM: aws-encryption-sdk-python
             REPO: awslabs/aws-encryption-sdk-python
@@ -407,13 +407,13 @@ jobs:
             PATH: josepy
           - DOWNSTREAM: mitmproxy
             REPO: mitmproxy/mitmproxy
-            # Latest commit on the mitmproxy main branch, as of Oct 22, 2026.
-            REF: 121030332aec790983bb8f3265cbfd32e6d7ba3f
+            # Latest commit on the mitmproxy main branch, as of Oct 23, 2026.
+            REF: 7cb38827580fa8a87af28c43441ab11132747e4a
             PATH: mitmproxy
           - DOWNSTREAM: scapy
             REPO: secdev/scapy
-            # Latest commit on the scapy master branch, as of Oct 22, 2026.
-            REF: 49b03612d33d9d0d52300ab651e9a02e017de738
+            # Latest commit on the scapy master branch, as of Oct 23, 2026.
+            REF: bf1b5405c2551063ff26fd9c9c176a972569648d
             PATH: scapy
           - DOWNSTREAM: sigstore-python
             REPO: sigstore/sigstore-python