diff --git a/modules/1plusXRtdProvider.js b/modules/1plusXRtdProvider.js
index 390f4f4cd81..3d859af9681 100644
--- a/modules/1plusXRtdProvider.js
+++ b/modules/1plusXRtdProvider.js
@@ -14,7 +14,6 @@ const ORTB2_NAME = '1plusX.com'
 const PAPI_VERSION = 'v1.0';
 const LOG_PREFIX = '[1plusX RTD Module]: ';
 const OPE_FPID = 'ope_fpid'
-const LEGACY_SITE_KEYWORDS_BIDDERS = ['appnexus'];
 export const segtaxes = {
   // cf. https://github.com/InteractiveAdvertisingBureau/openrtb/pull/108
   AUDIENCE: 526,
@@ -152,17 +151,6 @@ const getTargetingDataFromPapi = (papiUrl) => {
  * @returns {Object} Object describing the updates to make on bidder configs
  */
 export const buildOrtb2Updates = ({ segments = [], topics = [] }, bidder) => {
-  // Currently appnexus bidAdapter doesn't support topics in `site.content.data.segment`
-  // Therefore, writing them in `site.keywords` until it's supported
-  // Other bidAdapters do fine with `site.content.data.segment`
-  const writeToLegacySiteKeywords = LEGACY_SITE_KEYWORDS_BIDDERS.includes(bidder);
-  if (writeToLegacySiteKeywords) {
-    const site = {
-      keywords: topics.join(',')
-    };
-    return { site };
-  }
-
   const userData = {
     name: ORTB2_NAME,
     segment: segments.map((segmentId) => ({ id: segmentId }))
@@ -216,14 +204,6 @@ export const updateBidderConfig = (bidder, ortb2Updates, bidderConfigs) => {
   return bidderConfigCopy;
 };
 
-const setAppnexusAudiences = (audiences) => {
-  config.setConfig({
-    appnexusAuctionKeywords: {
-      '1plusX': audiences,
-    },
-  });
-}
-
 /**
  * Updates bidder configs with the targeting data retreived from Profile API
  * @param {Object} papiResponse Response from Profile API
@@ -243,10 +223,6 @@ export const setTargetingDataToConfig = (papiResponse, { bidders }) => {
         config: updatedBidderConfig
       });
     }
-    if (bidder === 'appnexus') {
-      // Do the legacy stuff for appnexus with segments
-      setAppnexusAudiences(segments);
-    }
   }
 }
 
diff --git a/test/spec/modules/1plusXRtdProvider_spec.js b/test/spec/modules/1plusXRtdProvider_spec.js
index 8657c37d7d8..1570785a5de 100644
--- a/test/spec/modules/1plusXRtdProvider_spec.js
+++ b/test/spec/modules/1plusXRtdProvider_spec.js
@@ -195,18 +195,6 @@ describe('1plusXRtdProvider', () => {
       }
       expect([ortb2Updates]).to.deep.include.members([expectedOutput]);
     });
-    it('fills site.keywords in the ortb2 config (appnexus specific)', () => {
-      const rtdData = { segments: fakeResponse.s, topics: fakeResponse.t };
-      const ortb2Updates = buildOrtb2Updates(rtdData, 'appnexus');
-
-      const expectedOutput = {
-        site: {
-          keywords: rtdData.topics.join(','),
-        }
-      }
-      expect([ortb2Updates]).to.deep.include.members([expectedOutput]);
-    });
-
     it('defaults to empty array if no segment is given', () => {
       const rtdData = { topics: fakeResponse.t };
       const ortb2Updates = buildOrtb2Updates(rtdData, randomBidder());
@@ -242,17 +230,6 @@ describe('1plusXRtdProvider', () => {
       }
       expect(ortb2Updates).to.deep.include(expectedOutput);
     })
-    it('defaults to empty string if no topic is given (appnexus specific)', () => {
-      const rtdData = { segments: fakeResponse.s };
-      const ortb2Updates = buildOrtb2Updates(rtdData, 'appnexus');
-
-      const expectedOutput = {
-        site: {
-          keywords: '',
-        }
-      }
-      expect(ortb2Updates).to.deep.include(expectedOutput);
-    })
   })
 
   describe('extractConsent', () => {
@@ -384,24 +361,6 @@ describe('1plusXRtdProvider', () => {
       expect(newBidderConfig.ortb2.user).to.deep.include(bidderConfigInitial.ortb2.user);
     })
 
-    it('merges fetched data in bidderConfig for configured bidders (appnexus specific)', () => {
-      const bidder = 'appnexus';
-      // Set initial config
-      config.setBidderConfig({
-        bidders: [bidder],
-        config: bidderConfigInitial
-      });
-      // Call submodule's setBidderConfig
-      const newBidderConfig = updateBidderConfig(bidder, ortb2UpdatesAppNexus, config.getBidderConfig());
-
-      // Check that the targeting data has been set in the config
-      expect(newBidderConfig).not.to.be.null;
-      expect(newBidderConfig.ortb2.site).to.deep.include(ortb2UpdatesAppNexus.site);
-      // Check that existing config didn't get erased
-      expect(newBidderConfig.ortb2.site).to.deep.include(bidderConfigInitial.ortb2.site);
-      expect(newBidderConfig.ortb2.user).to.deep.include(bidderConfigInitial.ortb2.user);
-    })
-
     it('overwrites an existing 1plus.com entry in ortb2.user.data', () => {
       const bidder = randomBidder();
       // Set initial config
@@ -495,7 +454,7 @@ describe('1plusXRtdProvider', () => {
     }
 
     it('sets the config for the selected bidders', () => {
-      const bidders = ['appnexus', 'rubicon'];
+      const bidders = ['rubicon'];
       // setting initial config for those bidders
       config.setBidderConfig({
         bidders,