diff --git a/.github/workflows/OCV-PR-Linux-Alpine.yaml b/.github/workflows/OCV-PR-Linux-Alpine.yaml
new file mode 100644
index 00000000..1caa61d8
--- /dev/null
+++ b/.github/workflows/OCV-PR-Linux-Alpine.yaml
@@ -0,0 +1,129 @@
+name: OCV PR Alpine Musl-C
+
+on:
+  pull_request:
+    branches:
+      - main
+    paths:
+      - '.github/workflows/OCV-PR-Linux-Alpine.yaml'
+      # TODO: are following paths necessary?
+      # - 'checkout-and-merge/*'
+      # - 'configure-and-build/*'
+      # - 'run-tests/*'
+      # - 'scripts/runner.py'
+      # - 'scripts/test-plan.json'
+  workflow_call:
+    inputs:
+      workflow_branch:
+        description: "Branch for ci-gha-workflow repository"
+        default: "main"
+        required: false
+        type: string
+
+concurrency:
+  group: OCV-PR-Linux-Alpine-${{ github.ref }}
+  cancel-in-progress: true
+
+jobs:
+
+  branch_eval:
+    runs-on: ubuntu-24.04
+    outputs:
+      branches: ${{ steps.determine-branches.outputs.branches }}
+    steps:
+        - id: determine-branches
+          shell: bash
+          run: |
+            if [ "${{ github.event.repository.name == 'ci-gha-workflow' }}" = "true" ] ; then
+              echo "branches=[ '4.x', '5.x' ]" >> "$GITHUB_OUTPUT"
+            else
+              echo "branches=[ '${{ github.base_ref }}' ]" >> "$GITHUB_OUTPUT"
+            fi
+
+  Alpine:
+    runs-on: opencv-cn-lin-x86-64
+    needs:
+      - branch_eval
+    strategy:
+      fail-fast: false
+      matrix:
+        branch: ${{ fromJSON(needs.branch_eval.outputs.branches )}}
+    defaults:
+      run:
+        shell: bash
+    container:
+      image: 'quay.io/opencv-ci/alpine-3:20260409'
+      volumes:
+        - /home/opencv-cn/git_cache:/opt/git_cache
+        - /home/opencv-cn/ci_cache/opencv/alpine-3:/opt/.ccache
+        - /home/opencv-cn/binaries_cache/alpine-3:/opt/binaries_cache
+        - /home/opencv-cn/dnn-models:/opt/dnn-models
+    env:
+      ANT_HOME: '/usr/share/ant'
+      DNN_MODELS: '/opt/dnn-models'
+      CCACHE_DIR: '/opt/.ccache'
+      CCACHE_MAXSIZE: '8G'
+      OPENCV_DOWNLOAD_PATH: '/opt/binaries_cache'
+      HOME: '/home/ci'
+      MAIN_BUILD_DIR: "build"
+      OPENCV_FOR_THREADS_NUM: 8
+      CMAKE_BUILD_PARALLEL_LEVEL: 8
+    steps:
+
+    - name: Checkout workflow repository
+      uses: actions/checkout@v4
+      with:
+        repository: opencv/ci-gha-workflow
+        ref: "${{ github.repository == 'opencv/ci-gha-workflow' && github.ref || inputs.workflow_branch }}"
+
+    - name: Checkout and merge OpenCV
+      uses: ./checkout-and-merge
+      with:
+        target_branch: "${{ matrix.branch }}"
+        author: "${{ github.event.pull_request.user.login }}"
+        source_branch: "${{ github.event.repository.name == 'ci-gha-workflow' && '' || github.head_ref }}"
+        gitcache: '/opt/git_cache'
+        home: '${{ env.HOME }}'
+        workdir: '${{ env.HOME }}'
+
+    - name: Update extra dnn models
+      timeout-minutes: 60
+      working-directory: '${{ env.HOME }}'
+      run: |
+        ls -lR ${{ env.DNN_MODELS }}
+        python3 opencv_extra/testdata/dnn/download_models.py \
+          --cleanup \
+          --dst '${{ env.DNN_MODELS }}/dnn'
+        echo "OPENCV_DNN_TEST_DATA_PATH=${{ env.DNN_MODELS }}" >> $GITHUB_ENV
+
+    - name: Configure and build OpenCV
+      uses: ./configure-and-build
+      with:
+        workdir: '${{ env.HOME }}'
+        builddir: 'build'
+        generator: 'Ninja'
+        options: '${{ env.CMAKE_OPT }}'
+
+    - name: Run OpenCV tests
+      uses: ./run-tests
+      env:
+        OPENCV_TEST_DATA_PATH: '${{ env.HOME }}/opencv_extra/testdata'
+        OPENCV_TEST_REQUIRE_DATA: 1
+        OPENCV_TEST_CHECK_OPTIONAL_DATA: 1
+        PYTHONPATH: '${{ env.HOME }}/${{ env.MAIN_BUILD_DIR }}/python_loader:$PYTHONPATH'
+      with:
+        workdir: '${{ env.HOME }}'
+        builddir: '${{ env.MAIN_BUILD_DIR }}'
+        logdir: '${{ env.HOME }}/${{ env.MAIN_BUILD_DIR }}'
+        plan: "test-plan-${{ matrix.branch }}.json"
+        suite: "[ 'linux' ]"
+        filter: "[ 'ubuntu-common', 'ubuntu-avx2' ]"
+        enable_python: "true"
+        enable_java: "true"
+        suffix: 'alpine3_${{ matrix.branch }}'
+
+    - if: ${{ always() && env.WARNINGS == '1' }}
+      name: Warnings check
+      run: |
+        echo "::error Warnings have been found!"
+        exit 1
diff --git a/docker/alpine/Dockerfile-musl b/docker/alpine/Dockerfile-musl
new file mode 100644
index 00000000..cc9865fc
--- /dev/null
+++ b/docker/alpine/Dockerfile-musl
@@ -0,0 +1,50 @@
+# version: 20260409
+# Image name: quay.io/opencv-ci/alpine-3
+FROM alpine:3.23.4
+
+ENV LD_LIBRARY_PATH=/usr/local/lib:$LD_LIBRARY_PATH
+
+RUN apk add --no-cache \
+    build-base \
+    diffutils \
+    cmake \
+    ccache \
+    bash \
+    git \
+    curl \
+    wget \
+    tar \
+    xz \
+    zlib-dev \
+    xz-dev \
+    nasm \
+    yasm \
+    pkgconfig \
+    openssl-dev \
+    libjpeg-turbo-dev \
+    fontconfig-dev \
+    freetype-dev \
+    expat-dev \
+    libpng-dev \
+    tiff-dev \
+    libvpx-dev \
+    libavif-dev \
+    ffmpeg-dev \
+    alsa-lib-dev \
+    musl-dev \
+    ttf-dejavu \
+    linux-headers \
+    py3-requests \
+    perl \
+    ninja
+
+#  user`s UID is 1000 for self-runner
+RUN adduser -D -u 1000 -h /home/ci ci && \
+    mkdir -p /home/ci /io && \
+    chown -R ci:ci /home/ci /io
+
+ENV HOME=/home/ci
+WORKDIR /home/ci
+USER ci
+
+ENV PATH "$HOME/bin:$PATH"