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51 lines (51 loc) · 1.88 KB
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cff-version: 1.2.0
message: "If you use LLM-PathwayCurator in your research, please cite it."
title: "LLM-PathwayCurator: Audit-gated decision-grade pathway claims from enrichment outputs"
type: software
version: 0.1.0
authors:
- family-names: "Furudate"
given-names: "Ken"
orcid: "https://orcid.org/0000-0003-1272-5490"
- family-names: "Takahashi"
given-names: "Koichi"
orcid: "https://orcid.org/0000-0002-8027-9659"
repository-code: "https://github.com/kenflab/LLM-PathwayCurator"
url: "https://github.com/kenflab/LLM-PathwayCurator"
license: "MIT"
keywords:
- "reproducible research"
- "computational biology"
- "quality assurance"
- "pathway analysis"
- "enrichment analysis"
- "fgsea"
- "GSEA"
- "Metascape"
- "abstention"
- "selective prediction"
- "LLM"
- "bioinformatics tool"
abstract: >
Enrichment interpretations invite plausible narratives. LLM-PathwayCurator
transforms enrichment outputs into auditable, evidence-linked claims with
redundancy-highlighting module mapping; across The Cancer Genome Atlas’s seven
cohorts, it achieved qualified coverage of 0.66–0.80 under matched context but
dropped to 0.20–0.42 under context swap and 0.20–0.30 after supporting-gene
dropout, reflecting contract violations or weakened gene support. By
transforming narratives into decision-grade claims with audit-gated
abstention, it establishes a reproducible quality-assurance layer for omics
interpretation.
preferred-citation:
type: software
title: "LLM-PathwayCurator: Audit-gated decision-grade pathway claims from enrichment outputs"
authors:
- family-names: "Furudate"
given-names: "Ken"
- family-names: "Takahashi"
given-names: "Koichi"
year: 2026
version: 0.1.0
doi: "10.5281/zenodo.18625777"
url: "https://github.com/kenflab/LLM-PathwayCurator"
repository-code: "https://github.com/kenflab/LLM-PathwayCurator"