diff --git a/e2e/images/ocsp/requirements.txt b/e2e/images/ocsp/requirements.txt
index b6d5e37d..097d30b9 100644
--- a/e2e/images/ocsp/requirements.txt
+++ b/e2e/images/ocsp/requirements.txt
@@ -1,2 +1,2 @@
 Flask~=3.1.3
-cryptography~=48.0.0
+cryptography~=49.0.0