diff --git a/changes/4572.feature.md b/changes/4572.feature.md
new file mode 100644
index 0000000000..a800dc88ad
--- /dev/null
+++ b/changes/4572.feature.md
@@ -0,0 +1 @@
+Force Wayland on WSL2 if the WSL2 GUI apps feature is enabled
diff --git a/gtk/src/toga_gtk/libs/gtk.py b/gtk/src/toga_gtk/libs/gtk.py
index 0880b8d265..ec89812182 100644
--- a/gtk/src/toga_gtk/libs/gtk.py
+++ b/gtk/src/toga_gtk/libs/gtk.py
@@ -98,7 +98,12 @@
         "environment variable set correctly?"
     )
 
-IS_WAYLAND = not isinstance(Gdk.Display.get_default(), GdkX11.X11Display)
+IS_WSL2_GUI_ENABLED = os.getenv("WSL2_GUI_APPS_ENABLED", "0") == "1"
+
+# Force Wayland on WSL2 if the WSL2 GUI apps feature is enabled
+IS_WAYLAND = (
+    not isinstance(Gdk.Display.get_default(), GdkX11.X11Display) or IS_WSL2_GUI_ENABLED
+)
 
 # The following imports will fail if the underlying libraries or their API wrappers
 # aren't installed; handle failure gracefully (see