From c959be100d80e70060232ec52c923ea3c1875839 Mon Sep 17 00:00:00 2001 From: Eduard Kerkhoven Date: Wed, 3 Sep 2025 23:04:45 +0200 Subject: [PATCH 1/3] fix: growth predictions under anaerobic conditions (#377) * fix: label axes of growth plot * fix: scaleBioMass balance_out to 1 g/gDCW * fix: anaerobicModel no overwrite of biomass comp. * chore: regenerate growth predictions --- code/modelTests/growth.m | 4 +-- code/otherChanges/anaerobicModel.m | 2 -- code/otherChanges/scaleBioMass.m | 39 ++++++++++++++++------------- data/testResults/growth.md | 2 +- data/testResults/growth.png | Bin 48590 -> 50258 bytes 5 files changed, 25 insertions(+), 22 deletions(-) diff --git a/code/modelTests/growth.m b/code/modelTests/growth.m index 7bc75afd..6e211899 100644 --- a/code/modelTests/growth.m +++ b/code/modelTests/growth.m @@ -53,8 +53,8 @@ x=0:0.001:lim; y = x; plot(x,y,'--','MarkerSize',6,'Color',[64,64,64]/256) -xlabel('Experimental growth rate [1/h]','FontSize',14,'FontName','Helvetica') -ylabel('In silico growth rate [1/h]','FontSize',14,'FontName','Helvetica') +xlabel('In silico growth rate [1/h]','FontSize',14,'FontName','Helvetica') +ylabel('Experimental growth rate [1/h]','FontSize',14,'FontName','Helvetica') legend(b,'N-limited aerobic','C-limited aerobic','C-limited anaerobic','N-limited anaerobic','Location','northwest') % meanerror = sqrt(sum(([exp_data1(:,4);exp_data2(:,4);exp_data3(:,4);exp_data4(:,4)]-[mod_data1(:,4);mod_data2(:,4);mod_data3(:,4);mod_data4(:,4)]).^2)/32)/sqrt(32); diff --git a/code/otherChanges/anaerobicModel.m b/code/otherChanges/anaerobicModel.m index 3ee6d8b4..a86c29f3 100644 --- a/code/otherChanges/anaerobicModel.m +++ b/code/otherChanges/anaerobicModel.m @@ -10,11 +10,9 @@ %1st change: Refit GAM and NGAM to exp. data, change biomass composition GAM = 30.49; %Data from Nissen et al. 1997 -P = 0.461; %Data from Nissen et al. 1997 NGAM = 0; %Refit done in Jouthen et al. 2012 model = changeGAM(model,GAM,NGAM); -model = scaleBioMass(model,'protein',P,'carbohydrate',false); %2nd change: Removes the requirement of heme a, NAD(PH), coenzyme A in the biomass equation % (not used under anaerobic conditions) diff --git a/code/otherChanges/scaleBioMass.m b/code/otherChanges/scaleBioMass.m index 07cbda2b..dab4282a 100644 --- a/code/otherChanges/scaleBioMass.m +++ b/code/otherChanges/scaleBioMass.m @@ -1,19 +1,24 @@ function model = scaleBioMass(model,component,new_value,balance_out,dispOutput) - % scaleBioMass - % Scales the biomass composition - % - % model (struct) metabolic model in COBRA format - % component (str) name of the component to rescale (e.g. "protein") - % new_value (float) new total fraction for said component - % balance_out (str, opt) if chosen, the name of another component with which - % the model will be balanced out so that the total mass remains = 1 g/gDW - % provide empty string '' if this should not be done - % dispOutput (bool, opt) if output from sumBioMass should be displayed (default = true) - % - % model (struct) modified model - % - % Usage: model = scaleBioMass(model,component,new_value,balance_out,dispOutput) - % +% scaleBioMass +% Scales the biomass composition +% +% Input: +% model (struct) yeast-GEM model +% component (string) biomass component to change (options are: +% 'carbohydrate', 'protein', 'lipid', 'RNA', 'DNA', +% 'ion', 'cofactor') +% new_value (num) new total fraction for the specified biomass +% component +% balance_out (string, optional) biomass component that will be used +% to balance out the biomass composition, so that the +% total mass adds up to 1 g/gDCW. This is highly +% recommended (default = empty, no scaling takes place) +% dispOutput (bool, optional) displayed outoupt (default = true) +% +% Output: +% model (struct) modified yeast-GEM model +% +% Usage: model = scaleBioMass(model,component,new_value,balance_out,dispOutput) if nargin < 5 dispOutput = true; @@ -30,13 +35,13 @@ old_value = eval(content_Cap{pos}); f = new_value / old_value; model = rescalePseudoReaction(model,component,f); +X = sumBioMass(model,false); %Balance out (if desired): if ~isempty(balance_out) pos = strcmp(content_all,balance_out); balance_value = eval(content_Cap{pos}); - f = (balance_value - (new_value - old_value)) / balance_value; + f = (balance_value + (1-X)) / balance_value; model = rescalePseudoReaction(model,balance_out,f); end - end diff --git a/data/testResults/growth.md b/data/testResults/growth.md index 8212950e..5155ef01 100644 --- a/data/testResults/growth.md +++ b/data/testResults/growth.md @@ -1,4 +1,4 @@ ## R2 of growth rate prediction 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zz&BSSlUrWAK%Dv3nb{0Lyz1wiOH|W(R4fRTr%~zVuH)yYfw-SF==sW{3jt{Lriw|*GupH8^`1E-|j)KhHeWu&NOXpZACX?RqA?=!C)Ln(+>Rk z^cO&Zoj&XiKF7f=&O7=l+MuYpXHU$Ly0XYkI;EVev^Mk69smCrF7lrmbqL{cd#T>g zFUiN#0GBb>Z{s+T)sRhwuab_=JW?isVQ9IUGmh&R8W_0uGwVH*P_w3{rsf@zeMN28 zhB_`L8c!cCQjB|o_IEC+B_0ZRjyu2Ne|Qxt#rpAv@*3DDdWySytFpb4 z3wzEuRcmZ=6VRif)}d%1dZX(NUiS%6K_Sjy1GSE7WMtp04Id91-z^2C^6<4bR5XzQ zBs-U8(KdH8`)_0lX;5*Ha?er^JRJsnf%+K2Z&-tPGjpue-yYP#NTnEWw<6o~%vOB$ zV(a_2dd94;5|NqH&rAL-&vrS_5CRz*C|pjn)2Hd2qgXD&o8cGJ;C*0JBMxCKDhfD+ zK$NE+KYoNb1XL|O5CCCI4YXtmR7C}maKN^VrZ+Z+3=9qNHp8$|k=w0*P4gWLpuT5C2P|@XU!B|! zC*J+3aC;?VwIs;Y-qEqqln?WD%}eA53Ah+*#CH((9zfP{wd|tM4x=FPheC~{%JWt6 zk^b{Ou20G>plR#OHwlA}`wF5wXKnt_g1@2mE!aFZK8;v^ O<@pnqAbAIDuKgd?lpVSN From 88041fb23afc1c1170235256a5bd88561268ad93 Mon Sep 17 00:00:00 2001 From: Eduard Kerkhoven Date: Mon, 29 Jun 2026 16:46:10 +0200 Subject: [PATCH 2/3] feat: curations and script for anaerobic metabolism (#386) * feat: initial model curations as defined in May * feat: separate general curations and test script * feat: separate glycine and nitrogen functions * A number of model mofications are suggested to improve the accuracy of anaerobic simulations and overall consistency with fermentative physiology. -Added data fluxomic data from 3 published works and extracellular product formation Nissen et al. 1996. Use anaerobic_flux_predictions.m to simulate. -A modification was added to growth.m and anaerobicModel.m such that the biomass composition of the anaerobic model does not override the one related with nitrogen limitation (see code more). -anaerobiosis.m runs all tests. -anaerobicModel. Summary of modifications in anaerobic model: -IDP2 blocked - Cofactor handling in biomass - Degree of reduction the biomass tweaked - FADH2 added to the biomass equation (succinate production through FRD1) -MAE1/NAPDH blocked * A number of modification are proposed to improve the accuracy and overall consistency of the yeast genome-scale metabolic model with experimental data and fermentation physiology. - Checked all proton symport/antiport reactions and make sure that they only enter the cell. - Balance reactions and ensures that a correct molecular weight can be calculated for the biomass - Some modifications are media dependent (Carnitine shuttle and GLT1) and need to moved elsewhere. - Curated several reactions in terms of reversibility and cofactor specificity. - A couple of modifications added need to revised: -'r_0441', 'r_0442': LOT6 seems to use FMN/FMNH2 as a cofactor instead of sustrate/product. Consider removing reactions. - Blocked ammonium transport to the mitochondria (ammonia can difuse in position to ammonium). * Updated code for flux predictions in anaerobic conditions. Loads txt isntead of xlsx. * FADH=0.06 mmol/gDW change txt to tsv extension in anaerobic flux predictions * Add files via upload * Update v9_0_2.m * Update anaerobicModel.m updated the FADH2 coefficient. * Update anaerobicModel.m Updates related with anaplerosis fixed the unusual flux through MAE1 and IDP1 (NADPH). * Update v9_0_2.m * Update anaerobicModel.m * Update anaerobicModel.m * refactor: anaerobicModel * fix: label axes of growth plot * fix: scaleBioMass balance_out to 1 g/gDCW * fix: anaerobicModel no overwrite of biomass comp. * chore: regenerate growth predictions * fix: anaerobicModel no rescale of biomass * fix: anaerobic_flux_predictions readtable * Update v9_1_0.m * feat: functions run from matlab path * feat: scaleBioMass reports final output * refactor: run functions from path + other refactor * feat: sumBioMass uses metFormulas not data files * feat: 9.1.0 curate r_0013 and biomass * WIP * fix: rxn balance curations and script refactor * WIP * feat: test reducing methionine content * feat: adapt amino acid content in biomass * feat: disable GCV except N-lim and Gly N-source * feat: make 9.1.0 model * refactor: update model loading to use earlier version 9.0.2 * feat: include anaerobic curation figures * feat: correct H+ in protein biomass pseudorxn * fix: v910_anaerobic_fluxes * fix: report CoD as R2 and not Pearson's r * feat: python anaerobic_model script * fix: recover some functions --------- Co-authored-by: davidhcsic Co-authored-by: davidhcsic <32391339+davidhcsic@users.noreply.github.com> --- README.md | 2 +- code/anaerobic_model.py | 232 + code/loadYeastModel.m | 13 +- code/modelCuration/v9_1_0.m | 409 + code/modelTests/anaerobic_flux_predictions.m | 65 + code/modelTests/anaerobiosis.m | 425 + code/modelTests/growth.m | 73 +- code/modelTests/plotAnaerobic.m | 30 + code/otherChanges/anaerobicModel.m | 84 +- code/otherChanges/anaerobicModelOld.m | 203 + code/otherChanges/changeAminoAcidRatio.m | 43 + code/otherChanges/fitGAM.m | 5 +- code/otherChanges/glycineNitrogenSource.m | 21 + code/otherChanges/nitrogenLimitation.m | 16 + code/otherChanges/rescalePseudoReaction.m | 27 +- code/otherChanges/scaleBioMass.m | 9 +- code/otherChanges/sumBioMass.m | 125 +- code/saveYeastModel.m | 6 +- data/databases/model_metDeltaG.csv | 62 +- data/databases/model_rxnDeltaG.csv | 33 +- data/physiology/aminoAcid_Bjorkeroth2020.tsv | 21 + .../biomassComposition_Forster2003.tsv | 1 + data/physiology/flux_data_anaerobic.tsv | 126 + data/testResults/v910_anaerobic_fluxes.png | Bin 0 -> 142631 bytes data/testResults/v910_anaerobic_sjoberg.png | Bin 0 -> 68559 bytes data/testResults/v910_growth.png | Bin 0 -> 154727 bytes model/dependencies.txt | 5 +- model/yeast-GEM.txt | 335 +- model/yeast-GEM.xml | 8613 ++++------ model/yeast-GEM.yml | 14299 +++++----------- 30 files changed, 9662 insertions(+), 15621 deletions(-) create mode 100644 code/anaerobic_model.py create mode 100644 code/modelCuration/v9_1_0.m create mode 100644 code/modelTests/anaerobic_flux_predictions.m create mode 100644 code/modelTests/anaerobiosis.m create mode 100644 code/modelTests/plotAnaerobic.m create mode 100644 code/otherChanges/anaerobicModelOld.m create mode 100644 code/otherChanges/changeAminoAcidRatio.m create mode 100644 code/otherChanges/glycineNitrogenSource.m create mode 100644 code/otherChanges/nitrogenLimitation.m create mode 100644 data/physiology/aminoAcid_Bjorkeroth2020.tsv create mode 100644 data/physiology/flux_data_anaerobic.tsv create mode 100644 data/testResults/v910_anaerobic_fluxes.png create mode 100644 data/testResults/v910_anaerobic_sjoberg.png create mode 100644 data/testResults/v910_growth.png diff --git a/README.md b/README.md index 0d1ea942..c4023317 100644 --- a/README.md +++ b/README.md @@ -39,7 +39,7 @@ This repository contains the current consensus genome-scale metabolic model of _ | Taxonomy | Latest update | Version | Reactions | Metabolites | Genes | |:-------|:--------------|:------|:------|:----------|:-----| -| _Saccharomyces cerevisiae_ | 23-Nov-2024 | develop | 4131 | 2806 | 1161 | +| _Saccharomyces cerevisiae_ | 27-May-2026 | develop | 4102 | 2748 | 1143 | # Installation & usage diff --git a/code/anaerobic_model.py b/code/anaerobic_model.py new file mode 100644 index 00000000..e5d0a492 --- /dev/null +++ b/code/anaerobic_model.py @@ -0,0 +1,232 @@ +"""Constrain yeast-GEM to anaerobic conditions (pure cobrapy). + +This is a self-contained port of ``code/otherChanges/anaerobicModel.m`` (and +the ``changeAminoAcidRatio`` / ``sumBioMass`` / ``rescalePseudoReaction`` +helpers it relies on) to cobrapy. It has no dependency on the RAVEN toolbox +or raven-python; the only third-party requirement is ``cobra``. + +By default yeast-GEM represents aerobic metabolism. :func:`anaerobic_model` +edits exchange reactions and a few intracellular reactions in place so the +model reaches the exchange rates measured under anaerobic batch growth on +minimal glucose media. + +Usage:: + + import cobra + from anaerobic_model import anaerobic_model + + model = cobra.io.read_sbml_model("model/yeast-GEM.xml") + anaerobic_model(model) +""" +from __future__ import annotations + +import csv +import re +from pathlib import Path + +import cobra + +# Repo paths: this file lives in ``code/``; the repo root is its parent. +_REPO_ROOT = Path(__file__).resolve().parent.parent +_AA_TSV = _REPO_ROOT / "data" / "physiology" / "aminoacid_Bjorkeroth2020.tsv" + +# Metabolite/reaction IDs reused across helpers. +_PROTON_ID = "s_0794" # H+ [cytoplasm] +_PROTEIN_RXN = "r_4047" # protein pseudoreaction +_PROTEIN_MET_NAME = "protein" # the protein pseudoreaction product (s_3717) + +# Atomic weights, identical to the table in ``sumBioMass.m`` +# (``parseChemicalFormula``). ``R`` is the generic residue placeholder and +# carries no mass, matching the MATLAB convention. +_ELEMENT_WEIGHTS = { + "C": 12.01, "H": 1.008, "N": 14.007, "O": 15.999, "P": 30.974, + "S": 32.06, "R": 0.0, "Fe": 55.845, "K": 39.098, "Na": 22.99, + "Cl": 35.45, "Mn": 54.938, "Zn": 65.38, "Ca": 40.078, "Mg": 24.305, + "Cu": 63.546, +} + +_FORMULA_TOKEN = re.compile(r"([A-Z][a-z]*)(\d*)") + + +def anaerobic_model(model: cobra.Model) -> cobra.Model: + """Constrain ``model`` to anaerobic conditions in place. + + Parameters + ---------- + model : cobra.Model + yeast-GEM model, aerobic by default. + + Returns + ------- + cobra.Model + The same model object, modified to match anaerobic conditions. + """ + # 1. Cofactor pseudoreaction (r_4598): heme a synthesis requires O2, so + # remove heme a from the biomass cofactor pool and rebalance protons. + cofactor_rxn = model.reactions.get_by_id("r_4598") + _set_coefficient(cofactor_rxn, model.metabolites.get_by_id("s_3714"), 0.0) + _rebalance_proton(model, cofactor_rxn) + + # 2. Switch the protein pseudoreaction to the anaerobic amino-acid ratio. + _change_amino_acid_ratio(model, aerobic=False) + + # 3. Exchange reactions: block O2 uptake, and open the sterol / fatty-acid + # / vitamin uptakes that are essential supplements for anaerobic growth. + lower_bounds = { + "r_1992": 0.0, # oxygen (block uptake) + "r_1757": -1000.0, # ergosterol + "r_1915": -1000.0, # lanosterol + "r_2106": -1000.0, # zymosterol + "r_2134": -1000.0, # 14-demethyllanosterol + "r_1994": -1000.0, # palmitoleate + "r_2189": -1000.0, # oleate + "r_2137": 0.0, # ergosta-5,7,22,24(28)-tetraen-3beta-ol (block) + "r_1967": -1000.0, # nicotinate + "r_1548": -1000.0, # (R)-pantothenate + } + for rxn_id, lower_bound in lower_bounds.items(): + model.reactions.get_by_id(rxn_id).lower_bound = lower_bound + + # 4. Block MDH2 (r_0714) and IDP2 (r_0659): repressed/undetected under + # anaerobic glucose growth. + for rxn_id in ("r_0714", "r_0659"): + model.reactions.get_by_id(rxn_id).bounds = (0.0, 0.0) + + # 5. Fumarate reductase recycles FADH2 from Ero1-driven disulphide-bond + # formation; add the net FADH2/FAD/H+ turnover to the biomass reaction. + biomass_rxn = model.reactions.get_by_id("r_4041") + fadh2_prod = 0.08 + biomass_rxn.add_metabolites( + { + model.metabolites.get_by_id("s_0689"): fadh2_prod, # FADH2 + model.metabolites.get_by_id("s_0687"): -fadh2_prod, # FAD + model.metabolites.get_by_id("s_0794"): -2.0 * fadh2_prod, # H+ + }, + combine=True, + ) + return model + + +# --- helpers ---------------------------------------------------------------- + +def _set_coefficient( + reaction: cobra.Reaction, metabolite: cobra.Metabolite, value: float +) -> None: + """Set an *absolute* stoichiometric coefficient (the ``S(i,j) = x`` + semantics of the MATLAB code). Setting ``value`` to 0 removes the + metabolite from the reaction. + """ + current = reaction.metabolites.get(metabolite, 0.0) + delta = float(value) - current + if delta != 0.0: + reaction.add_metabolites({metabolite: delta}, combine=True) + + +def _rebalance_proton(model: cobra.Model, reaction: cobra.Reaction) -> None: + """Set the H+ coefficient so ``reaction`` is charge balanced. + + Mirrors the H+ correction repeated in ``anaerobicModel.m`` and + ``rescalePseudoReaction.m``: zero the proton, then set it to the negative + of the remaining charge imbalance. Missing charges (cobra ``None``) are + treated as zero, matching MATLAB's ``'omitnan'``. + """ + proton = model.metabolites.get_by_id(_PROTON_ID) + _set_coefficient(reaction, proton, 0.0) + imbalance = sum( + (met.charge or 0.0) * coeff for met, coeff in reaction.metabolites.items() + ) + _set_coefficient(reaction, proton, -imbalance) + + +def _change_amino_acid_ratio(model: cobra.Model, *, aerobic: bool = True) -> None: + """Rewrite the protein pseudoreaction's amino-acid ratios. + + Port of ``changeAminoAcidRatio.m``. The protein mass is snapshotted, the + tRNA stoichiometries in ``r_4047`` are replaced with the aerobic or + anaerobic ratios from ``aminoacid_Bjorkeroth2020.tsv``, and the protein + pseudoreaction is rescaled so the protein fraction returns to its + pre-switch value. + """ + target_protein = _protein_mass(model) + + protein_rxn = model.reactions.get_by_id(_PROTEIN_RXN) + # TSV columns (0-indexed): 0 aa, 1 substrate met, 2 product met, 3 MW, + # 4 aerobic ratio, 5 anaerobic ratio. + ratio_column = 4 if aerobic else 5 + for row in _read_amino_acid_ratios(): + ratio = float(row[ratio_column]) + substrate = model.metabolites.get_by_id(row[1]) + product = model.metabolites.get_by_id(row[2]) + _set_coefficient(protein_rxn, substrate, -ratio) + _set_coefficient(protein_rxn, product, ratio) + + factor = target_protein / _protein_mass(model) + _rescale_protein(model, factor) + + +def _protein_mass(model: cobra.Model) -> float: + """Protein fraction [g/gDW], port of ``sumBioMass.m`` ``getFraction('P')``. + + Sums the molecular weight of the protein pseudoreaction substrates, with + two protons (2.016) removed from each charged-tRNA formula. + """ + protein_rxn = model.reactions.get_by_id(_PROTEIN_RXN) + total = 0.0 + for met, coeff in protein_rxn.metabolites.items(): + if coeff < 0: # substrate + total += -coeff * (_formula_weight(met) - 2.016) + return total / 1000.0 + + +def _rescale_protein(model: cobra.Model, factor: float) -> None: + """Multiply every coefficient in the protein pseudoreaction by ``factor`` + except the ``protein`` product, then rebalance H+. + + Port of ``rescalePseudoReaction.m`` for the protein component. + """ + protein_rxn = model.reactions.get_by_id(_PROTEIN_RXN) + deltas = { + met: (factor - 1.0) * coeff + for met, coeff in protein_rxn.metabolites.items() + if met.name != _PROTEIN_MET_NAME + } + if deltas: + protein_rxn.add_metabolites(deltas, combine=True) + _rebalance_proton(model, protein_rxn) + + +def _formula_weight(metabolite: cobra.Metabolite) -> float: + """Molecular weight from a metabolite formula, using the same atomic + weights as ``sumBioMass.m`` (so the generic residue ``R`` weighs 0).""" + formula = metabolite.formula + if not formula: + raise ValueError( + f"Biomass metabolite {metabolite.id} has an empty formula field." + ) + weight = 0.0 + for element, count in _FORMULA_TOKEN.findall(formula): + if not element: + continue + try: + weight += (int(count) if count else 1) * _ELEMENT_WEIGHTS[element] + except KeyError as exc: + raise ValueError( + f"Unknown element '{element}' in formula '{formula}'." + ) from exc + return weight + + +def _read_amino_acid_ratios() -> list[list[str]]: + """Read ``aminoacid_Bjorkeroth2020.tsv`` (one header line, tab separated). + + Returns the data rows verbatim; columns are + ``[aa, substrate_met, product_met, MW, aerobic, anaerobic]``. + """ + rows: list[list[str]] = [] + with open(_AA_TSV, newline="", encoding="utf-8") as handle: + reader = csv.reader(handle, delimiter="\t") + next(reader) # skip header + for record in reader: + if record and record[0].strip(): + rows.append(record) + return rows diff --git a/code/loadYeastModel.m b/code/loadYeastModel.m index 0b9ba1c7..b4452931 100644 --- a/code/loadYeastModel.m +++ b/code/loadYeastModel.m @@ -14,19 +14,19 @@ % % Usage: model = loadYeastModel(filename) +funcDir = dbstack('-completenames'); +funcDir = regexprep(funcDir(1).file,[funcDir(1).name '\.m'],''); + if nargin<1 || isempty(filename) - filename = '../model/yeast-GEM.yml'; + filename = fullfile(funcDir,'..','model','yeast-GEM.yml'); end -scriptFolder = fileparts(which(mfilename)); -currentDir = cd(scriptFolder); -cd(currentDir) if endsWith(filename,{'.yml','.yaml'}) model = readYAMLmodel(filename); else if ~(exist('ravenCobraWrapper.m','file')==2) if exist('readCbModel.m','file')==2 - warning(['RAVEN cannot be found. yeast-GEM will instead be loaded in '... + warning(['RAVEN cannot be found. Attempt to load yeast-GEM in '... 'COBRA format.\n\nNote that it is recommended to have RAVEN '... 'installed, especially when curating yeast-GEM (see README.md for '... 'more info).%s'],'') @@ -38,7 +38,8 @@ else model = importModel(filename); end - cd missingFields + currentDir = pwd; + cd(fullfile(funcDir,'missingFields')); model = loadDeltaG(model); cd(currentDir) end diff --git a/code/modelCuration/v9_1_0.m b/code/modelCuration/v9_1_0.m new file mode 100644 index 00000000..d192f825 --- /dev/null +++ b/code/modelCuration/v9_1_0.m @@ -0,0 +1,409 @@ +% This scripts applies curations to be applied on yeast-GEM release 9.0.2, +% to get to yeast-GEM release 9.1.0. +% +% Most curations in this lrease are related to improving the model +% performance in anaerobic conditions. + +%% Load yeast-GEM 9.0.2 (requires local yeast-GEM git repository) +cd .. +codeDir=pwd(); +model = getEarlierModelVersion('9.0.2'); +model.id='yeastGEM_develop'; +model.version=''; +% dataDir=fullfile(pwd(),'..','data','modelCuration','v9.1.0'); % No dataDir required for these curations +cd modelCuration + +%% ======================================================================== +% We blocked MDH2 in anaerobic conditions (see details in the anerobicModel +% script) Experiments suggest that AKG needs to produced inside the +% mitochondria and exported with ODC1/2 the help or YHM2. After inspecting +% the kinetics parameters for OAC1, DIC1, YHM2 and ODC1/ODC2 (SFC1 is +% strongly repressed by glucose) we added sulphate and malate as substrate +% for the OAC1 transporter. + +% Add sulphate[m] +newMet = struct('metNames', {{'sulphate'}}, ... + 'compartments', {{'m'}}); +model = addMets(model,newMet,true,'s_'); +fprintf('Identifier of new metabolite "%s[%s]": %s\n', newMet.metNames{1}, newMet.compartments{1}, model.mets{end}); + +% Add oxaloacetate/sulphate antiporter +newRxn = struct('rxns', {generateNewIds(model,'rxns','r_',1)}, ... + 'equations', {{'oxaloacetate[c] + sulphate[m] <=> oxaloacetate[m] + sulphate[c]'}}, ... + 'rxnNames', {{'oxaloacetate/sulphate antiport, mitochondrial'}}, ... + 'subSystems', {{'Transport [c, m]'}}, ... + 'grRules', {{'YKL120W'}},... + 'rxnReferences', {{'10.1074/jbc.274.32.22184'}}, ... + 'rxnConfidenceScores', {3}); +model = addRxns(model,newRxn,3); +fprintf('Identifier of new reaction "%s": %s\n', newRxn.rxnNames{1}, model.rxns{end}); + +% Add malate/sulphate antiporter +newRxn = struct('rxns', {generateNewIds(model,'rxns','r_',1)}, ... + 'equations', {{'(S)-malate[c] + sulphate[m] <=> (S)-malate[m] + sulphate[c]'}}, ... + 'rxnNames', {{'malate/sulphate antiport, mitochondrial'}}, ... + 'subSystems', {{'Transport [c, m]'}}, ... + 'grRules', {{'YKL120W'}},... + 'rxnReferences', {{'10.1074/jbc.274.32.22184'}}, ... + 'rxnConfidenceScores', {3}); +model = addRxns(model,newRxn,3); +fprintf('Identifier of new reaction "%s": %s\n', newRxn.rxnNames{1}, model.rxns{end}); + +%% ======================================================================== +% Look for all proton symport/antiport reactions and make sure that they +% only enter the cell. +HcytIdx = getIndexes(model,'s_0794','mets'); % H+[c] +HextIdx = getIndexes(model,'s_0796','mets'); % H+[e] + +symporterIDs = transpose(find(model.S(HcytIdx,:) & model.S(HextIdx,:))); +for i = 1:length(symporterIDs) + if ismember(model.rxns(symporterIDs(i)), {'r_1258'}) + % Ignore the sodium transporter, without it, the model does not work + continue + end + if model.S(HextIdx,symporterIDs(i))<0 % If defined H+[e] => H+[c] + model.lb(symporterIDs(i))=0; + else % If defined H+[c] => H+[e] + model.ub(symporterIDs(i))=0; + end +end + +%% ======================================================================== +% This section balances reactions and ensures that a correct molecular +% weight can be calculated for the biomass + +% Set the charge of all biomass components to 0 +model.metCharges(strcmp(model.mets,'s_3717'))=0; % Protein +model.metCharges(strcmp(model.mets,'s_3718'))=0; % Carbohydrate +model.metCharges(strcmp(model.mets,'s_3719'))=0; % RNA +model.metCharges(strcmp(model.mets,'s_3720'))=0; % DNA +model.metCharges(strcmp(model.mets,'s_3746'))=0; % Lipid backbone +model.metCharges(strcmp(model.mets,'s_3747'))=0; % Lipid chain +model.metCharges(strcmp(model.mets,'s_4205'))=0; % Cofactor +model.metCharges(strcmp(model.mets,'s_4206'))=0; % Ion + +% Make the charge of K and Na 1+ +model.metCharges(strcmp(model.mets,'s_1373'))=1; +model.metCharges(strcmp(model.mets,'s_1374'))=1; +model.metCharges(strcmp(model.mets,'s_3776'))=1; +model.metCharges(strcmp(model.mets,'s_1437'))=1; +model.metCharges(strcmp(model.mets,'s_1438'))=1; +model.metCharges(strcmp(model.mets,'s_3775'))=1; + +% Balance the charge of all biomass component pseudo reactions by adding the required amount of H+ +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4047')) = -sum(model.S(:,strcmp(model.rxns,'r_4047')).*model.metCharges,'omitnan'); % Protein +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4049')) = -sum(model.S(:,strcmp(model.rxns,'r_4049')).*model.metCharges,'omitnan'); % RNA +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4050')) = -sum(model.S(:,strcmp(model.rxns,'r_4050')).*model.metCharges,'omitnan'); % DNA +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4598')) = -sum(model.S(:,strcmp(model.rxns,'r_4598')).*model.metCharges,'omitnan'); % Cofactor +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4599')) = -sum(model.S(:,strcmp(model.rxns,'r_4599')).*model.metCharges,'omitnan'); % Ion + +% Special case for SLIME rxns +model.metCharges(find(contains(model.metNames,'chain')+contains(model.metNames,'backbone'))) = 0; + +% Now, based on the charge balance, find all the reactions that are +% imbalanced, add or remove hydrogen as necessary + +% Balance the charge of all imbalanced SLIME reactions by adding the +% required amount of H+, +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_3975')) = -sum(model.S(:,strcmp(model.rxns,'r_3975')).*model.metCharges,'omitnan'); % Protein +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_3976')) = -sum(model.S(:,strcmp(model.rxns,'r_3976')).*model.metCharges,'omitnan'); % Protein +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_3977')) = -sum(model.S(:,strcmp(model.rxns,'r_3977')).*model.metCharges,'omitnan'); % Protein +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_3978')) = -sum(model.S(:,strcmp(model.rxns,'r_3978')).*model.metCharges,'omitnan'); % Protein +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4076')) = -sum(model.S(:,strcmp(model.rxns,'r_4076')).*model.metCharges,'omitnan'); % Protein +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4077')) = -sum(model.S(:,strcmp(model.rxns,'r_4077')).*model.metCharges,'omitnan'); % Protein +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4078')) = -sum(model.S(:,strcmp(model.rxns,'r_4078')).*model.metCharges,'omitnan'); % Protein +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4079')) = -sum(model.S(:,strcmp(model.rxns,'r_4079')).*model.metCharges,'omitnan'); % Protein + +% Make the charge of HS (hydrogen sulfide) -1 +model.metCharges(strcmp(model.mets,'s_0841'))=-1; +model.metCharges(strcmp(model.mets,'s_3906'))=-1; +model.metCharges(strcmp(model.mets,'s_4263'))=-1; + +% Now manually balance some additional reactions + +% Balance the reactions 'r_0774' and 'r_0775', 'NAPRtase' by removing H+ +% consumption and adding a H2O as a reactant +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_0774'))=0; % Cytosolic +model.S(find(strcmp(model.mets,'s_0803')),strcmp(model.rxns,'r_0774'))=-1; % Cytosolic +model.S(find(strcmp(model.mets,'s_0799')),strcmp(model.rxns,'r_0775'))=0; % Mitochondrial +model.S(find(strcmp(model.mets,'s_0807')),strcmp(model.rxns,'r_0775'))=-1; % Mitochondrial + +% Balance the reaction r_0721, 'malonyl-CoA-ACP transacylase' by adding a +% proton as reactant +model.S(find(strcmp(model.mets,'s_0799')),strcmp(model.rxns,'r_0721'))=-1; + +% Balance the reaction r_1603, '4-amino-5-hydroxymethyl-2-methylpyrimidine synthetase' +% by adding a proton as reactant +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_1603'))=-1; + +% Balance the reactions r_2142-2144, 'B-ketoacyl-ACP synthase' by removing +% proton as reactant +model.S(find(strcmp(model.mets,'s_0799')),ismember(model.rxns,{'r_2142','r_2143','r_2144'}))=0; + +% Balance the reactions r_2232, 'peroxisomal acyl-CoA thioesterase (4:0)' +% by correcting H+ +model.S(find(strcmp(model.mets,'s_0801')),strcmp(model.rxns,'r_2232')) = 1; + +% Balance the reaction r_4629, 'alcohol acyltransferase (hexanoyl-CoA)' +% by adding a proton as product +model.S(find(strcmp(model.mets,'s_0799')),strcmp(model.rxns,'r_4629')) = +4; + +% Balance the reaction r_4322, 'GPI mannosyltransferase 4' +% by removing proton +model.S(find(strcmp(model.mets,'s_0795')),strcmp(model.rxns,'r_4322')) = 0; + +% Balance the reaction r_4679, 'short-chain-fatty-acid-CoA ligase (propionate)' +% by adding a proton as product +model.S(find(strcmp(model.mets,'s_0801')),strcmp(model.rxns,'r_4679')) = 1; + +% Balance the reaction r_4701, 'L-cysteine hydrogen-sulfide-lyase' +% by adding a proton as product +model.S(find(strcmp(model.mets,'s_0799')),strcmp(model.rxns,'r_4701')) = 1; + +% Balance the reaction r_4702, 'L-cysteine:2-oxoglutarate aminotransferase' +% by adding a proton as reactant +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4702'))=-1; + +% Balance the reaction r_4703, '3-mercaptopyruvate sulfurtransferase' +% by adding a proton as product +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4703'))=1; + +% Balance the reaction r_4707, 'trithionate thiosulfohydrolase' +% by adding a proton as product +model.S(find(strcmp(model.mets,'s_0794')),strcmp(model.rxns,'r_4707'))=1; + +%% ======================================================================== +% This section focuses on individual reactions that have the wrong +% reversibility/direction/cofactor or should be completely removed + +% Make GCY1 irreversible. Has a positive DeltaGo' (+20.9) and is part of a +% transhydrogenase cycle (NADH -> NADPH) at the cost of one ATP. High +% cytosolic NADPH/NADP ratio makes it thermodynamically infeasible that it +% runs in reverse direction. First swap direction, then make irreversible +model.S(:,strcmp(model.rxns,'r_0487')) = -model.S(:,strcmp(model.rxns,'r_0487')); +model = setParam(model,'lb','r_0487',0); +model = setParam(model,'rev','r_0226',0); + +% The mitochondrial ATP synthase is able to run in reverse, which occurs +% in anaerobic conditions +model = setParam(model,'lb','r_0226',-1000); +model = setParam(model,'rev','r_0226',1); + +% Rename r_0227, it is the plasma membrane ATPase, not a cytosolic ATPase +model.rxnNames(strcmp(model.rxns,'r_0227')) = {'ATPase, plasma membrane'}; + +% Make sure both formate-THF ligases are reversible (r_0447 already is). +model = setParam(model,'lb','r_0446',-1000); +model = setParam(model,'rev','r_0446',1); + +% Make methylenetetrahydrofolate dehydrogenases ADE3 and MIS1 irreversible +% First swap direction, then make irreversible +model.S(:,strcmp(model.rxns,'r_0732')) = -model.S(:,strcmp(model.rxns,'r_0732')); +model.S(:,strcmp(model.rxns,'r_0733')) = -model.S(:,strcmp(model.rxns,'r_0733')); +model = setParam(model,'lb',{'r_0732','r_0733'},0); +model = setParam(model,'rev',{'r_0732','r_0733'},1); + +% There is no evidence for this PFK1 side reaction in yeast +model = removeReactions(model,'r_0887',true,true,true); + +% TYR1 incorrectly annotated as using NAD, should be NADP +model.S(find(strcmp(model.mets,'s_1212')),strcmp(model.rxns,'r_0939'))=0; %NADPH +model.S(find(strcmp(model.mets,'s_1207')),strcmp(model.rxns,'r_0939'))=0; %NADP +model.S(find(strcmp(model.mets,'s_1203')),strcmp(model.rxns,'r_0939'))=1; %NADH +model.S(find(strcmp(model.mets,'s_1198')),strcmp(model.rxns,'r_0939'))=-1;%NAD + +% Make esterification reactions irreversible. positive deltaG +model.ub(strcmp(model.rxns,'r_4713')) = 0; %diethyl succinate +model.ub(strcmp(model.rxns,'r_4714')) = 0; %monoethyl succinate + +% Make polyphosphate hydrolase and diphosphate transport over cell membrane +% both irreversible +model = setParam(model,'lb',{'r_4723','r_4724','r_4725'},0); + +% While r_0013 was elementary balanced, it was not charged balanced. The +% reaction mechanism was incorrect. Corrected to mimic a combination of +% MetaCyc rxns: R83-RXN and R147-RXN; or KEGG rxns: R07364 and R07395. +model = changeRxns(model,'r_0013','5-(methylsulfanyl)-2,3-dioxopentyl phosphate[c] + H2O[c] + oxygen[c] => 4-methylthio-2-oxobutanoate[c] + formate[c] + 2 H+[c] + phosphate[c]',3); + +% Correct product and reactant of r_2236 and r_2254, part of peroxisomal +% beta-oxidation, where the intermediate metabolite should be +% trans-but-2-enoyl-CoA, not but-2-enoyl-CoA +metsToAdd.metNames = 'trans-but-2-enoyl-CoA'; +metsToAdd.compartments = 'p'; +metsToAdd.metSmiles = 'C/C=C/C(=O)SCCNC(=O)CCNC(=O)[C@@H](C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O'; +metsToAdd.metFormulas = 'C25H36N7O17P3S'; +metsToAdd.metCharges = -4; +metsToAdd.metMiriams{1} = struct('name',{{'chebi';'metanetx.chemical'}},... + 'value',{{'CHEBI:50998';'MNXM1364409'}}); + +model = addMets(model,metsToAdd,false,'s_'); +model = removeMets(model, {'but-2-enoyl-CoA'}, true, true, true, true); +model.S(end,ismember(model.rxns,'r_2236')) = 1; +model.S(end,ismember(model.rxns,'r_2254')) = -1; +model.S(find(strcmp(model.mets,'s_0801')),ismember(model.rxns,'r_2236')) = 0; +model.S(find(strcmp(model.mets,'s_0801')),ismember(model.rxns,'r_2254')) = 0; +model.S(find(strcmp(model.mets,'s_0801')),ismember(model.rxns,'r_2284')) = +4; + +% Represent ACP with formula "RHS" +model.metFormulas(getIndexes(model,'s_1845','mets')) = {'RHS'}; + +% Set formula of ferr(i/o)cytochrome b3 +idx_mit = getIndexes(model,{'s_3826','s_3827'},'mets'); +idx_erm = getIndexes(model,{'s_4210','s_4209'},'mets'); +model.metFormulas(idx_erm) = model.metFormulas(idx_mit); +model.metCharges(idx_erm) = model.metCharges(idx_mit); +model.metMiriams(idx_erm) = model.metMiriams(idx_mit); +model.metNames([idx_mit; idx_erm]) = regexprep(model.metNames([idx_mit; idx_erm]),'F','f'); + +% Correct metFormula and metCharge +idx = getIndexes(model,{'s_4265','s_4266'},'mets'); +model.metFormulas(idx) = {'CH2O3S'}; +model.metCharges(idx) = -1; + +% Copy annotations between same metabolites in separate compartments +model.metFormulas(getIndexes(model,'s_4211','mets')) = model.metFormulas(getIndexes(model,'s_2885','mets')); +model.metCharges(getIndexes(model,'s_4211','mets')) = model.metCharges(getIndexes(model,'s_2885','mets')); +model.metFormulas(getIndexes(model,'s_4209','mets')) = model.metFormulas(getIndexes(model,'s_3826','mets')); +model.metCharges(getIndexes(model,'s_4209','mets')) = model.metCharges(getIndexes(model,'s_3826','mets')); +model.metMiriams(getIndexes(model,'s_4209','mets')) = model.metMiriams(getIndexes(model,'s_3826','mets')); + +% r_4323 is an less precise half-reaction of r_4324 and will be removed +model = removeReactions(model,'r_4323',true,true,true); + +% r_4325 represents scaffolding during [Fe-S]-cluster synthesis, not a +% metabolic process, and will therefore be removed +model = removeReactions(model,'r_4325',true,true,true); + +% r_4568 is an unbalanced, dead-end, non-gene-associated reaction without +% known reaction mechanism +model = removeReactions(model,'r_4568',true,true,true); + +% r_4704, r_4706 and r_4709 revolve around the unspecific metabolite +% alkanesulfonate, with unbalanced r_4706 +model = removeReactions(model,{'r_4704','r_4706','r_4709'},true,true,true); + +% r_4225, is a generic sterol transport reaction with YDR051C and YOL075C +% genes that are not proven to have sterol transport activity +model = removeReactions(model,'r_4225',true,true,true); + +% r_4199, r_4200, r_4201, r_4207, r_4215 are unspecific glutathione S-transferase +% reactions +model = removeReactions(model,{'r_4199','r_4200','r_4201','r_4207','r_4215'},true,true,true); + +% r_2441-r_2445 are catalyzed by YGR046W, remove general YGR046W reaction +model = changeGrRules(model,{'r_2441','r_2442','r_2443','r_2444','r_2445'},'YGR046W',true); +model = removeReactions(model,'r_4251'); + +% YDL052C/SLC1 (1-acyl-sn-glycerol-3-phosphate acyltransferase) should only +% be in lipid particles, not ER. Instead, YPR139C has 18:1 specificity +model = changeGrRules(model,{'r_2333', 'r_2335', 'r_2337'},'YOR175C or YPR139C', true); +% r_4277 is generic reaction, and above curations replace it +model = removeReactions(model,'r_4277',true,true,true); + +% r_4233, r_4239, r_4256, r_4258, r_4278', r_4280, r_4281, r_4324 and r_4340 +% act on protein pseudometabolites, but protein modifications are outside +% of the scope of a metabolic model +model = removeReactions(model,{'r_4233','r_4239','r_4256','r_4258','r_4278','r_4280','r_4281','r_4324','r_4340'},true,true,true); + +% r_4173, r_4246, r_4252 and r_4308 are generic (sulfur) reactions, unconnected to +% the rest of the network +model = removeReactions(model,{'r_4173','r_4246','r_4252','r_4308'},true,true,true); + +% remove generic riboNTP hydrolase r_4265 and replace with curation of r_0807 +model = removeReactions(model,'r_4265',true,true,true); +model = changeGrRules(model,'r_0807','YJR069C', true); + +% remove r_4759 mRNA decapping protein, r_4193 histone deacetylase, outside +% of metabolic scope +model = removeReactions(model,{'r_4759','r_4193'},true,true,true); + +%% ======================================================================== +% Condition-specific gene expression. These can be enabled with scripts +% Glycine cleavage only active when glycine is used as nitrogen source +model = setParam(model,'eq','r_0501',0); %glycine cleavage, mitochondrion +model = setParam(model,'eq','r_0507',0); %glycine cleavage complex (lipoylprotein), mitochondrion +model = setParam(model,'eq','r_0509',0); %glycine cleavage complex (lipoamide), mitochondrion +model.rxnNotes(ismember(model.rxns,{'r_0501','r_0507','r_0509'})) = {'Only active if glycine is nitrogen source, or under nitrogen restriction'}; + +% Glutamate synthase repressed in excess nitrogen +model = setParam(model,'eq','r_0472',0); +model.rxnNotes(ismember(model.rxns,{'r_0472'})) = {'Only active during nitrogen restriction'}; + +% The carnitine shuttle requires exogeneous carnitine, which is absent from +% defined medium. +model = setParam(model,'eq',{'r_0252'},0); +model.rxnNotes(ismember(model.rxns,{'r_0252'})) = {'Only active if growth medium contains carnitine'}; + +%% Update amino acid ratio with Björkeroth 2020 data +% Matching ratio in anaerobicModel function +model = changeAminoAcidRatio(model,1); + +%% Rescale protein fraction so that biomass sums up to 1 g/gDCW +% Protein is the largest fraction, so increasing +[X,P] = sumBioMass(model, false); +fprintf('Current biomass adds up to %.4f g/g. Protein fraction is scaled from %.4f to %.4f g/g to reach 1 g/g total biomass.\n', X, P, (1-X)+P) +model = scaleBioMass(model,'protein',(1-X)+P); + +%% Correct H+ balance in biomass component pseudoreactions +% Set the charge of all biomass components to 0 +model.metCharges(strcmp(model.mets,'s_3717'))=0; % Protein +model.metCharges(strcmp(model.mets,'s_3718'))=0; % Carbohydrate +model.metCharges(strcmp(model.mets,'s_3719'))=0; % RNA +model.metCharges(strcmp(model.mets,'s_3720'))=0; % DNA +model.metCharges(strcmp(model.mets,'s_3746'))=0; % Lipid backbone +model.metCharges(strcmp(model.mets,'s_3747'))=0; % Lipid chain +model.metCharges(strcmp(model.mets,'s_4205'))=0; % Cofactor +model.metCharges(strcmp(model.mets,'s_4206'))=0; % Ion + +% Balance the charge of all biomass component pseudo reactions by adding the required amount of H+ +Hc = find(strcmp(model.mets,'s_0794')); % H+[c] +model.S(Hc,strcmp(model.rxns,'r_4047')) = 0; +model.S(Hc,strcmp(model.rxns,'r_4047')) = -sum(model.S(:,strcmp(model.rxns,'r_4047')).*model.metCharges,'omitnan'); % Protein +model.S(Hc,strcmp(model.rxns,'r_4049')) = 0; +model.S(Hc,strcmp(model.rxns,'r_4049')) = -sum(model.S(:,strcmp(model.rxns,'r_4049')).*model.metCharges,'omitnan'); % RNA +model.S(Hc,strcmp(model.rxns,'r_4050')) = 0; +model.S(Hc,strcmp(model.rxns,'r_4050')) = -sum(model.S(:,strcmp(model.rxns,'r_4050')).*model.metCharges,'omitnan'); % DNA +model.S(Hc,strcmp(model.rxns,'r_4598')) = 0; +model.S(Hc,strcmp(model.rxns,'r_4598')) = -sum(model.S(:,strcmp(model.rxns,'r_4598')).*model.metCharges,'omitnan'); % Cofactor +model.S(Hc,strcmp(model.rxns,'r_4599')) = 0; +model.S(Hc,strcmp(model.rxns,'r_4599')) = -sum(model.S(:,strcmp(model.rxns,'r_4599')).*model.metCharges,'omitnan'); % Ion + +%% Degree of reduction of biomass +% To align the degree of reduction of S. cerevisiae biomass to the +% published value of 4.2 /Cmol (Lange and Heijnen, 2001, 10.1002/bit.10054) + +DR = 3; % 3mmol (g CDW)−1s +metIdx = getIndexes(model,{'s_1212','s_1207','s_0794'},'mets'); % NADPH[c], NADP[c], H+[c] +bioIdx = getIndexes(model,'r_4041','rxns'); + +currCoeff = full(model.S(metIdx,bioIdx)); % Gather the current coefficients +model.S(metIdx,bioIdx) = currCoeff + [-DR; +DR; -DR]; + +%% Enable glycine secretion to allow anaerobic growth +% WORKAROUND: anaerobiosis is only allowed if a small amount of glycine +% secretion is allowed, as overflow from THF produce by methionine synthase +% if glycine cleavage system is inactive (= in nitrogen-excess and with +% non-glycine nitrogen sources). +model = setParam(model,'lb',{'r_1173'},-1000); + +%% ======================================================================== + +%% DO NOT CHANGE OR REMOVE THE CODE BELOW THIS LINE. +% Show some metrics: +cd(fullfile(codeDir,'modelTests')) +disp('Run gene essentiality analysis') +[new.accuracy,new.tp,new.tn,new.fn,new.fp] = essentialGenes(model); +fprintf('Genes in model: %d\n',numel(model.genes)); +fprintf('Gene essentiality accuracy: %.4f\n', new.accuracy); +fprintf('True non-essential genes: %d\n', numel(new.tp)); +fprintf('True essential genes: %d\n', numel(new.tn)); +fprintf('False non-essential genes: %d\n', numel(new.fp)); +fprintf('False essential genes: %d\n', numel(new.fn)); +fprintf('\nRun growth analysis\n') +R2=growth(model); +fprintf('R2 of growth prediction: %.4f\n', R2); + +% Save model: +cd .. +saveYeastModel(model) +cd modelCuration diff --git a/code/modelTests/anaerobic_flux_predictions.m b/code/modelTests/anaerobic_flux_predictions.m new file mode 100644 index 00000000..5b377d98 --- /dev/null +++ b/code/modelTests/anaerobic_flux_predictions.m @@ -0,0 +1,65 @@ +function R2=anaerobic_flux_predictions(model) + +fluxTable = readtable('../../data/physiology/flux_data_anaerobic.tsv','FileType','text'); +fluxTable = table2cell(fluxTable); +vals_flux=fluxTable; +text_flux=fluxTable; + +sim_vals=[]; + +colors = orderedcolors("glow12"); + +data_sets=unique(text_flux(:,6)); +merged_data=[]; +merged_sim=[]; +merged_names=[]; + +for i=1:length(data_sets) + % Gather single data set + idx_data_set = find(strcmp(text_flux(:,6),data_sets(i,1))); + idx_glc = idx_data_set(strcmp(text_flux(idx_data_set,7),'r_1714')); + % Set glucose uptake + model = setParam(model,'eq','r_1714',-cell2mat(vals_flux(idx_glc,4))); + % Solve the LP problem + res=solveLP(model,1); + % Organize data and output + rxns = text_flux(idx_data_set,7); + include_data = ismember(rxns,model.rxns); + + rxns(~include_data) = []; + idx_data_set(~include_data) = []; + + idx_model = getIndexes(model,rxns,'rxns'); + + scaled_sim=abs(-100.*res.x(idx_model)./res.x(getIndexes(model,'r_1714','rxns'))); + + data_vals=abs(cell2mat(vals_flux(idx_data_set,5))); + merged_data=[merged_data data_vals']; + merged_sim=[merged_sim scaled_sim']; + merged_names=[merged_names rxns']; + plot(data_vals,scaled_sim,'^','MarkerFaceColor',colors(i,:),'MarkerEdgeColor',colors(i,:)); + hold on; + +end + + + +threshold=30; +% R2 = coefficient of determination about the line of identity, with the +% experimental values (merged_data) as reference; all data points (no threshold). +R2 = 1 - sum((merged_data-merged_sim).^2)/sum((merged_data-mean(merged_data)).^2); +mean_relative_error = mean(abs((merged_sim-merged_data)./merged_data),'omitnan'); + +x=0:1:threshold; +y = x; +plot(x,y,'--','MarkerSize',6,'Color',[64,64,64]/256) +ylim([0 threshold]) +xlim([0 threshold]) +text(12,threshold/2-10,['mean relative error: ' num2str(mean_relative_error)]); +text(12,threshold/2-5,['R^2: ' num2str(R2)]); + +legend(data_sets); +xlabel('Experimental 100 \cdot v_i/v_{Glx}','FontSize',14,'FontName','Helvetica') +ylabel('In silico 100 \cdot v_i/v_{Glx}','FontSize',14,'FontName','Helvetica'); + +end \ No newline at end of file diff --git a/code/modelTests/anaerobiosis.m b/code/modelTests/anaerobiosis.m new file mode 100644 index 00000000..34c53aec --- /dev/null +++ b/code/modelTests/anaerobiosis.m @@ -0,0 +1,425 @@ +clear; close all +% Load the old and new model +model902 = getEarlierModelVersion('9.0.2'); +model910 = getEarlierModelVersion('9.1.0'); + +%% Run growth tests +funcs = {@growth, @growthOld, @growth, @growthOld}; +models = {model910, model910, model902, model902}; +titles = {'v9.1.0 model, new anaerobic script', ... + 'v9.1.0 model, old anaerobic script', ... + 'v9.0.2 model, new anaerobic script', ... + 'v9.0.2 model, old anaerobic script'}; + +fig1 = figure('Name', 'Growth Comparison', 'Position', [100 100 1000 800]); +for k = 1:4 + subplot(2,2,k); + funcs{k}(models{k}); + title(titles{k}); +end +sgtitle('Growth: v9.1.0 vs v9.0.2, new vs old anaerobic script'); +saveas(fig1, '..\..\data\testResults\v910_growth.png'); + +% R2 of growth prediction increased from 0.8256 to 0.9085 as result of all +% curations. + +%% Convert to anaerobic +cd('../otherChanges/') +modelAn910 = anaerobicModel(model910); +modelAnOld910 = anaerobicModelOld(model910); +modelAn902 = anaerobicModel(model902); +modelAnOld902 = anaerobicModelOld(model902); + +%% Anaerobic flux predictions +cd('../modelTests/'); +models = {modelAn910, modelAnOld910, modelAn902, modelAnOld902}; +titles = {'v9.1.0 model, new anaerobic script', ... + 'v9.1.0 model, old anaerobic script', ... + 'v9.0.2 model, new anaerobic script', ... + 'v9.0.2 model, old anaerobic script'}; +fig2 = figure('Name', 'Anaerobic Comparison', 'Position', [100 100 1000 800]); +for k = 1:4 + subplot(2,2,k); + anaerobic_flux_predictions(models{k}); + title(titles{k}); +end +sgtitle('Anaerobic flux predictions: v9.1.0 vs v9.0.2, new vs old anaerobic script'); +saveas(fig2, '..\..\data\testResults\v910_anaerobic_fluxes.png'); + +% R2 of flux predictions increased from 0.7858 to 0.9175 as a response to +% all curations + +%% Plot +models = {modelAn910, modelAnOld910, modelAn902, modelAnOld902}; +titles = {'v9.1.0 model, new anaerobic script', ... + 'v9.1.0 model, old anaerobic script', ... + 'v9.0.2 model, new anaerobic script', ... + 'v9.0.2 model, old anaerobic script'}; +fig3 = figure('Name', 'Anaerobic Comparison', 'Position', [100 100 1000 800]); +for k = 1:4 + subplot(2,2,k); + plotAnaerobic(models{k}); + title(titles{k}); +end +sgtitle('Anaerobic fluxes (Sjöberg data): v9.1.0 vs v9.0.2, new vs old anaerobic script'); +saveas(fig3, '..\..\data\testResults\v910_anaerobic_sjoberg.png'); + +%% Set glucose uptake rate and solve pFBA +temp_model = setParam(modelAn910,'eq','r_1714',-23); +res=solveLP(temp_model,1); FLUX = res.x; + +v_AStr = res.x(getIndexes(temp_model,'r_1115','rxns')); % Ammonium exchange +v_ATPase = res.x(getIndexes(temp_model,'r_0227','rxns')); % ATPase +v_glc = res.x(getIndexes(temp_model,'r_1714','rxns')); % Glucose uptake +[v_AStr, v_ATPase, v_glc]; + +fprintf("Ratio of ammonium sulfate exchange / ATPase: %.02f\n", v_AStr / v_ATPase) + +% Ratio of ammonium sulfate / ATPase is 1.072, close to the measured 1. + +%% Pack flux results into table +rxns_reacs=constructEquations(temp_model,temp_model.rxns); +tab=table(temp_model.rxns,temp_model.rxnNames,rxns_reacs,abs(FLUX./v_glc),FLUX,temp_model.grRules); + +% [massImbalance, imBalancedMass, imBalancedCharge, imBalancedRxnBool, elements, missingFormulaeBool, balancedMetBool] = checkMassChargeBalance(temp_model); +% +% tabImbalance = [tab,table(imBalancedRxnBool,imBalancedCharge,imBalancedMass)]; +% tabImbalance(~imBalancedRxnBool,:) = []; +% % Filter out exchange and SLIME reactions, these are known to be unbalanced +% tabImbalance(contains(tabImbalance.Var2,'exchange'),:) = []; +% tabImbalance(contains(tabImbalance.Var2,'SLIME'),:) = []; + + +%% Calculate formula and degree of reduciton of biomass +% [mwRange,metFormulae,elements,metEle]=computeMetFormulae(modelAn,'metMwRange','s_0450','fillMets','none','printLevel',0); +% Biomass_index = find(strcmp(modelAn.metNames,'biomass')); +% %Degree of reduction per element. Order of the elements 'C', 'H', 'O', 'N' +% DR_per_ele = [4, 1, -2, -3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]; +% DR_per_Cmol=sum(metEle(Biomass_index,:).*DR_per_ele)/metEle(Biomass_index,1) +% Biomass_formula_Cmol=metEle(Biomass_index,:)/metEle(Biomass_index,1); +% MW_per_Cmol_min = mwRange/metEle(Biomass_index,1) +% +% + +%% Old functions +function R2 = growthOld(model_origin,writeOutput) +% This is for growth test: Fig S4c for yeast8 paper +% here we use several chemostat data: 'N-limited aerobic' 'C-limited +% aerobic' 'C-limited anaerobic' 'N-limited anaerobic' +% when simulating N-limited condition, protein content was rescaled, and +% when simulate anaerobic condtion, heme NADH NADP NADPH NAD were rescaled +% to be 0. + +funcDir = fileparts(mfilename('fullpath')); + +if nargin<1 + model_origin = loadYeastModel; +end +if nargin<2 + writeOutput = false; +end + +%Load chemostat data: +fid = fopen(fullfile(funcDir,'..','..','data','physiology','chemostatData_Tobias2013.tsv'),'r'); +exp_data = textscan(fid,'%f32 %f32 %f32 %f32','Delimiter','\t','HeaderLines',1); +exp_data = [exp_data{1} exp_data{2} exp_data{3} exp_data{4}]; +fclose(fid); +exp_data1 = exp_data(1:9,:); +exp_data2 = exp_data(10:20,:); +exp_data3 = exp_data(21:26,:); +exp_data4 = exp_data(27:32,:); + +%'N-limited aerobic' +mod_data(1:9,:) = simulateChemostat(model_origin,exp_data(1:9,:),1,'N'); +%'C-limited aerobic' +mod_data(10:20,:) = simulateChemostat(model_origin,exp_data(10:20,:),1,'C'); +%'C-limited anaerobic' +mod_data(21:26,:) = simulateChemostat(model_origin,exp_data(21:26,:),2,'C'); +%'N-limited anaerobic' +mod_data(27:32,:) = simulateChemostat(model_origin,exp_data(27:32,:),2,'N'); + +% plot the figure +hold on +cols = [215,25,28;253,174,97;171,217,233;44,123,182]/256; +b(1) = plot(exp_data(1:9,4),mod_data(1:9,4),'o','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(2,:)); +b(2) = plot(exp_data(10:20,4),mod_data(10:20,4),'s','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(1,:)); +b(3) = plot(exp_data(21:26,4),mod_data(21:26,4),'d','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(3,:)); +b(4) = plot(exp_data(27:32,4),mod_data(27:32,4),'>','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(4,:)); +exp_max = max(exp_data(:,4)); +mod_max = max(mod_data(:,4)); +lim = max(exp_max,mod_max)+0.05; +xlim([0 lim]) +ylim([0 lim]) +x=0:0.001:lim; +y = x; +plot(x,y,'--','MarkerSize',6,'Color',[64,64,64]/256) +xlabel('Experimental growth rate [1/h]','FontSize',14,'FontName','Helvetica') +ylabel('In silico growth rate [1/h]','FontSize',14,'FontName','Helvetica') +legend(b,'N-limited aerobic','C-limited aerobic','C-limited anaerobic','N-limited anaerobic','Location','northwest') + +% meanerror = sqrt(sum(([exp_data1(:,4);exp_data2(:,4);exp_data3(:,4);exp_data4(:,4)]-[mod_data1(:,4);mod_data2(:,4);mod_data3(:,4);mod_data4(:,4)]).^2)/32)/sqrt(32); +% text(0.25,0.1,['SEM:',num2str(meanerror)]) +hold off +R2=corrcoef(exp_data(:,4),mod_data(:,4)); +R2=R2(2)^2; +text(0.25,0.1,['R2:',num2str(R2)]) + +if writeOutput + saveas(gcf,fullfile(funcDir,'..','..','..','data','testResults','growth.png')); + fid = fopen(fullfile(funcDir,'..','..','..','data','testResults','growth.md'),'w'); + fprintf(fid,'%s\n','## R2 of growth rate prediction'); + fprintf(fid,'%.4g\n\n',R2); + fprintf(fid,'%s\n','![Growth curve](growth.png)'); + fclose(fid); +end +end + +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% +function [mod_data,solresult] = simulateChemostat(model_origin,exp_data,mode1,mode2) +%Relevant positions: +pos(1) = find(strcmp(model_origin.rxns,'r_1714')); %glc +pos(2) = find(strcmp(model_origin.rxns,'r_1992')); %O2 +pos(3) = find(strcmp(model_origin.rxns,'r_1654')); %NH3 +pos(4) = find(strcmp(model_origin.rxns,'r_2111')); %growth + +%Simulate chemostats: +mod_data = zeros(size(exp_data)); +solresult = zeros(length(model_origin.rxns),length(exp_data(:,1))); +if mode1 == 2 + model_origin = anaerobicModelOld(model_origin); +end +if strcmp(mode2,'N') + % P content in NH3-lim 0.1/h chemostat, per 10.1016/j.femsyr.2005.04.003 + model_origin = scaleBioMassOld(model_origin,'protein',0.28,'',false); + % Assume that RNA decreased by the same amount (40%) + model_origin = scaleBioMassOld(model_origin,'RNA',0.0329,'carbohydrate',false); + model_origin = setParam(model_origin,'ub','r_0472',1000); %Glutamate synthase repressed in excess nitrogen +end +for i = 1:length(exp_data(:,1)) + model_test= model_origin; + %Fix glucose uptake rate and maximize growth: + for j = 1:length(exp_data(1,:))-1 + + if abs(exp_data(i,j))==1000 + model_test = setParam(model_test,'lb',model_test.rxns(pos(j)),-exp_data(i,j)); + else + model_test = setParam(model_test,'eq',model_test.rxns(pos(j)),-exp_data(i,j)); + end + end + + model_test = setParam(model_test,'obj',model_test.rxns(pos(4)),1); + sol = solveLP(model_test,1); + %Store relevant variables: + try + mod_data(i,:) = abs(sol.x(pos)'); + solresult(:,i) = sol.x; + catch + mod_data(i,:) = 0; + solresult(:,i) = 0; + end +end +end + +function model = anaerobicModelOld(model) +% anaerobicModelOld +% This file has been replaced with anaerobicModel since yeast-GEM 9.1.0. +% This function is kept just for comparison purposes. +% +% Inputs: model (struct) aerobic model +% Output: model (struct) anaerobic model +% +% Usage: model = anaerobicModel(model) +% + +%1st change: Refit GAM and NGAM to exp. data, change biomass composition +GAM = 30.49; %Data from Nissen et al. 1997 +P = 0.461; %Data from Nissen et al. 1997 +NGAM = 0; %Refit done in Jouthen et al. 2012 + +model = changeGAM(model,GAM,NGAM); +model = scaleBioMassOld(model,'protein',P,'carbohydrate',false); + +%2nd change: Removes the requirement of heme a, NAD(PH), coenzyme A in the biomass equation +% (not used under anaerobic conditions) +mets = {'s_3714','s_1198','s_1203','s_1207','s_1212','s_0529'}; +[~,met_index] = ismember(mets,model.mets); +model.S(met_index,strcmp(model.rxns,'r_4598')) = 0; + +%3rd change: Changes media to anaerobic (no O2 uptake and allows sterol +% and fatty acid exchanges) +model.lb(strcmp(model.rxns,'r_1992')) = 0; %O2 +model.lb(strcmp(model.rxns,'r_1757')) = -1000; %ergosterol +model.lb(strcmp(model.rxns,'r_1915')) = -1000; %lanosterol +model.lb(strcmp(model.rxns,'r_1994')) = -1000; %palmitoleate +model.lb(strcmp(model.rxns,'r_2106')) = -1000; %zymosterol +model.lb(strcmp(model.rxns,'r_2134')) = -1000; %14-demethyllanosterol +model.lb(strcmp(model.rxns,'r_2137')) = -1000; %ergosta-5,7,22,24(28)-tetraen-3beta-ol +model.lb(strcmp(model.rxns,'r_2189')) = -1000; %oleate + +%4th change: Blocked pathways for proper glycerol production +%Block oxaloacetate-malate shuttle (not present in anaerobic conditions) +model.lb(strcmp(model.rxns,'r_0713')) = 0; %Mithocondria +model.lb(strcmp(model.rxns,'r_0714')) = 0; %Cytoplasm +%Block glycerol dehydroginase (only acts in microaerobic conditions) +model.ub(strcmp(model.rxns,'r_0487')) = 0; +%Block 2-oxoglutarate + L-glutamine -> 2 L-glutamate (alternative pathway) +model.ub(strcmp(model.rxns,'r_0472')) = 0; +end + +function model = scaleBioMassOld(model,component,new_value,balance_out,dispOutput) + % scaleBioMass + % Scales the biomass composition + % + % model (struct) metabolic model in COBRA format + % component (str) name of the component to rescale (e.g. "protein") + % new_value (float) new total fraction for said component + % balance_out (str, opt) if chosen, the name of another component with which + % the model will be balanced out so that the total mass remains = 1 g/gDW + % provide empty string '' if this should not be done + % dispOutput (bool, opt) if output from sumBioMass should be displayed (default = true) + % + % model (struct) modified model + % + % Usage: model = scaleBioMass(model,component,new_value,balance_out,dispOutput) + % + +if nargin < 5 + dispOutput = true; +end +if nargin < 4 + balance_out = ''; +end + +%Measure current composition and rescale: +[~,P,C,R,D,L,I,F] = sumBioMassOld(model,dispOutput); +content_all = {'carbohydrate','protein','lipid','RNA','DNA','ion','cofactor'}; +content_Cap = {'C','P','L','R','D','I','F'}; +pos = strcmp(content_all,component); +old_value = eval(content_Cap{pos}); +f = new_value / old_value; +model = rescalePseudoReaction(model,component,f); + +%Balance out (if desired): +if ~isempty(balance_out) + pos = strcmp(content_all,balance_out); + balance_value = eval(content_Cap{pos}); + f = (balance_value - (new_value - old_value)) / balance_value; + model = rescalePseudoReaction(model,balance_out,f); +end +end + +function [X,P,C,R,D,L,I,F] = sumBioMassOld(model,dispOutput) + % sumBioMass + % Calculates breakdown of biomass + % + % model (struct) Metabolic model in COBRA format + % dispOutput (bool, opt) If output should be displayed (default = true) + % + % X (float) Total biomass fraction [gDW/gDW] + % P (float) Protein fraction [g/gDW] + % C (float) Carbohydrate fraction [g/gDW] + % R (float) RNA fraction [g/gDW] + % D (float) DNA fraction [g/gDW] + % L (float) Lipid fraction [g/gDW] + % F (float) cofactor [g/gDW] + % I (float) ion [g/gDW] + % + % Usage: [X,P,C,R,D,L,I,F] = sumBioMass(model,dispOutput) + % + % Function adapted from SLIMEr: https://github.com/SysBioChalmers/SLIMEr + % + +if nargin < 2 + dispOutput = true; +end + +%Load original biomass component MWs: +%TODO: compute MW automatically from chemical formulas (check that all components have them first) +fid = fopen('../../data/physiology/biomassComposition_Forster2003.tsv'); +Forster2003 = textscan(fid,'%s %s %f32 %f32 %s','Delimiter','\t','HeaderLines',1); +data.mets = Forster2003{1}; +data.MWs = double(Forster2003{4}); +fclose(fid); + +%load additional cofactor/ion MWs: +fid = fopen('../../data/physiology/biomassComposition_Cofactor_Ion.tsv'); +CofactorsIons = textscan(fid,'%s %s %f32 %f32 %s %s','Delimiter','\t','HeaderLines',1); +data_new.mets = CofactorsIons{1}; +data_new.MWs = double(CofactorsIons{4}); +fclose(fid); +for i = 1:length(data_new.mets) + if ~ismember(data_new.mets(i),data.mets) + data.mets = [data.mets; data_new.mets(i)]; + data.MWs = [data.MWs; data_new.MWs(i)]; + end +end + +%Get main fractions: +[P,X] = getFraction(model,data,'P',0,dispOutput); +[C,X] = getFraction(model,data,'C',X,dispOutput); +[R,X] = getFraction(model,data,'R',X,dispOutput); +[D,X] = getFraction(model,data,'D',X,dispOutput); +[L,X] = getFraction(model,data,'L',X,dispOutput); +[I,X] = getFraction(model,data,'I',X,dispOutput); +[F,X] = getFraction(model,data,'F',X,dispOutput); + +if dispOutput + disp(['X -> ' num2str(X) ' gDW/gDW']) + % Simulate growth: + sol = solveLP(model,1); + disp(['Growth = ' num2str(sol.f) ' 1/h']) + disp(' ') +end + +end + +%% + +function [F,X] = getFraction(model,data,compType,X,dispOutput) + +%Define pseudoreaction name: +rxnName = [compType ' pseudoreaction']; +rxnName = strrep(rxnName,'P','protein'); +rxnName = strrep(rxnName,'C','carbohydrate'); +rxnName = strrep(rxnName,'N','biomass'); +rxnName = strrep(rxnName,'L','lipid backbone'); +rxnName = strrep(rxnName,'R','RNA'); +rxnName = strrep(rxnName,'D','DNA'); +rxnName = strrep(rxnName,'I','ion'); +rxnName = strrep(rxnName,'F','cofactor'); + +%Add up fraction: +rxnPos = strcmp(model.rxnNames,rxnName); +if ~all(rxnPos==0) + isSub = model.S(:,rxnPos) < 0; %substrates in pseudo-rxn + if strcmp(compType,'L') + F = -sum(model.S(isSub,rxnPos)); %g/gDW + else + F = 0; + %Add up all components: + for i = 1:length(model.mets) + pos = strcmp(data.mets,model.mets{i}); + if isSub(i) && sum(pos) == 1 + if strcmp(compType,'I') || strcmp(compType,'F') + MW = data.MWs(pos); + else + MW = data.MWs(pos)-18; + end + abundance = -model.S(i,rxnPos)*MW/1000; + F = F + abundance; + end + end + end + X = X + F; + + if dispOutput + disp([compType ' -> ' num2str(F) ' g/gDW']) + end +else + if dispOutput + disp([compType ' does not exist ']) + end + F = 0; + X = X + F; +end +end diff --git a/code/modelTests/growth.m b/code/modelTests/growth.m index 6e211899..0ab6ef96 100644 --- a/code/modelTests/growth.m +++ b/code/modelTests/growth.m @@ -6,72 +6,71 @@ % when simulate anaerobic condtion, heme NADH NADP NADPH NAD were rescaled % to be 0. +funcDir = dbstack('-completenames'); +funcDir = regexprep(funcDir(1).file,[funcDir(1).name '\.m'],''); + if nargin<1 - cd .. model_origin = loadYeastModel; - cd otherChanges/ -else - cd ../otherChanges/ end if nargin<2 writeOutput = false; end %Load chemostat data: -fid = fopen('../../data/physiology/chemostatData_Tobias2013.tsv','r'); +fid = fopen(fullfile(funcDir,'..','..','data','physiology','chemostatData_Tobias2013.tsv'),'r'); exp_data = textscan(fid,'%f32 %f32 %f32 %f32','Delimiter','\t','HeaderLines',1); exp_data = [exp_data{1} exp_data{2} exp_data{3} exp_data{4}]; fclose(fid); -%'N-limited aerboic' exp_data1 = exp_data(1:9,:); -%'C-limited aerobic' exp_data2 = exp_data(10:20,:); -%'C-limited anaerobic' exp_data3 = exp_data(21:26,:); -%'N-limited anaerobic' exp_data4 = exp_data(27:32,:); -mod_data1 = simulateChemostat(model_origin,exp_data1,1,'N'); -mod_data2 = simulateChemostat(model_origin,exp_data2,1,'C'); -mod_data3 = simulateChemostat(model_origin,exp_data3,2,'C'); -mod_data4 = simulateChemostat(model_origin,exp_data4,2,'N'); +%'N-limited aerobic' +mod_data(1:9,:) = simulateChemostat(model_origin,exp_data(1:9,:),1,'N'); +%'C-limited aerobic' +mod_data(10:20,:) = simulateChemostat(model_origin,exp_data(10:20,:),1,'C'); +%'C-limited anaerobic' +mod_data(21:26,:) = simulateChemostat(model_origin,exp_data(21:26,:),2,'C'); +%'N-limited anaerobic' +mod_data(27:32,:) = simulateChemostat(model_origin,exp_data(27:32,:),2,'N'); -cd ../modelTests/ % plot the figure -figure hold on cols = [215,25,28;253,174,97;171,217,233;44,123,182]/256; -b(1) = plot(exp_data1(:,4),mod_data1(:,4),'o','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(2,:)); -b(2) = plot(exp_data2(:,4),mod_data2(:,4),'s','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(1,:)); -b(3) = plot(exp_data3(:,4),mod_data3(:,4),'d','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(3,:)); -b(4) = plot(exp_data4(:,4),mod_data4(:,4),'>','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(4,:)); -exp_max = max(exp_data2(:,4)); -mod_max = max(mod_data1(:,4)); +b(1) = plot(exp_data(1:9,4),mod_data(1:9,4),'o','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(2,:)); +b(2) = plot(exp_data(10:20,4),mod_data(10:20,4),'s','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(1,:)); +b(3) = plot(exp_data(21:26,4),mod_data(21:26,4),'d','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(3,:)); +b(4) = plot(exp_data(27:32,4),mod_data(27:32,4),'>','MarkerSize',10,'MarkerEdgeColor','k','MarkerFaceColor',cols(4,:)); +exp_max = max(exp_data(:,4)); +mod_max = max(mod_data(:,4)); lim = max(exp_max,mod_max)+0.05; xlim([0 lim]) ylim([0 lim]) x=0:0.001:lim; y = x; plot(x,y,'--','MarkerSize',6,'Color',[64,64,64]/256) -xlabel('In silico growth rate [1/h]','FontSize',14,'FontName','Helvetica') -ylabel('Experimental growth rate [1/h]','FontSize',14,'FontName','Helvetica') +xlabel('Experimental growth rate [1/h]','FontSize',14,'FontName','Helvetica') +ylabel('In silico growth rate [1/h]','FontSize',14,'FontName','Helvetica') legend(b,'N-limited aerobic','C-limited aerobic','C-limited anaerobic','N-limited anaerobic','Location','northwest') % meanerror = sqrt(sum(([exp_data1(:,4);exp_data2(:,4);exp_data3(:,4);exp_data4(:,4)]-[mod_data1(:,4);mod_data2(:,4);mod_data3(:,4);mod_data4(:,4)]).^2)/32)/sqrt(32); % text(0.25,0.1,['SEM:',num2str(meanerror)]) hold off -R2=corrcoef([exp_data1(:,4);exp_data2(:,4);exp_data3(:,4);exp_data4(:,4)],[mod_data1(:,4);mod_data2(:,4);mod_data3(:,4);mod_data4(:,4)]); -R2=R2(2)^2; +% R2 = coefficient of determination about the line of identity, with the +% experimental values as reference; all data points (no thresholding). +obs = exp_data(:,4); pred = mod_data(:,4); +R2 = 1 - sum((obs-pred).^2)/sum((obs-mean(obs)).^2); +text(0.25,0.1,['R2:',num2str(R2)]) if writeOutput - saveas(gcf,'../../data/testResults/growth.png'); - fid = fopen('../../data/testResults/growth.md','w'); + saveas(gcf,fullfile(funcDir,'..','..','data','testResults','growth.png')); + fid = fopen(fullfile(funcDir,'..','..','data','testResults','growth.md'),'w'); fprintf(fid,'%s\n','## R2 of growth rate prediction'); fprintf(fid,'%.4g\n\n',R2); fprintf(fid,'%s\n','![Growth curve](growth.png)'); fclose(fid); end - end %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% @@ -85,14 +84,22 @@ %Simulate chemostats: mod_data = zeros(size(exp_data)); solresult = zeros(length(model_origin.rxns),length(exp_data(:,1))); -if strcmp(mode2,'N') - model_origin = scaleBioMass(model_origin,'protein',0.289,'',false); - model_origin = scaleBioMass(model_origin,'lipid',0.048,'',false); - model_origin = scaleBioMass(model_origin,'RNA',0.077,'carbohydrate',false); -end + if mode1 == 2 model_origin = anaerobicModel(model_origin); end + +if strcmp(mode2,'N') + % P content in NH3-lim 0.1/h chemostat, per 10.1016/j.femsyr.2005.04.003 + model_origin = scaleBioMass(model_origin,'protein',0.28,'',false); + % Assume that RNA decreased by the same amount (40%) + model_origin = scaleBioMass(model_origin,'RNA',0.0329,'carbohydrate',false); + % Glutamate synthase derepressed under nitrogen limitation + model_origin = setParam(model_origin,'ub','r_0472',1000); + % Glycine cleavage system is derepressed under nitrogen limitation + model_origin = setParam(model_origin,'ub',{'r_0501','r_0507','r_0509'},1000); +end + for i = 1:length(exp_data(:,1)) model_test= model_origin; %Fix glucose uptake rate and maximize growth: diff --git a/code/modelTests/plotAnaerobic.m b/code/modelTests/plotAnaerobic.m new file mode 100644 index 00000000..41dab03e --- /dev/null +++ b/code/modelTests/plotAnaerobic.m @@ -0,0 +1,30 @@ +function plotAnaerobic(modelAn) +modelAn = setParam(modelAn,'eq','r_1714',-23); +res=solveLP(modelAn,1); +FLUX=res.x; + +%% Retrieve data for the main products +v_glc=FLUX(getIndexes(modelAn,'r_1714','rxns'),:); +v_eth=FLUX(getIndexes(modelAn,'r_1761','rxns'),:); +v_CO2=FLUX(getIndexes(modelAn,'r_1672','rxns'),:); +v_gly=FLUX(getIndexes(modelAn,'r_1808','rxns'),:); +v_growth=FLUX(getIndexes(modelAn,'r_4041','rxns'),:); +v_AStr = FLUX(getIndexes(modelAn,'r_1115','rxns')); +v_ATPase = FLUX(getIndexes(modelAn,'r_0227','rxns')); +%% Show relative accuracy of main extracellular products +%figure; +%glycerol ethanol Co2 +%4.5 ± 0.4 31 ± 2 38 ± 10 +data=[4.5 31 38 0.36]; +sim=[v_gly v_eth v_CO2 v_growth]; +errorVal=[0.4 2 10 0.02]; +b1=bar(data./data,'FaceAlpha',0.5);hold on;b2=bar(sim./data,'FaceAlpha',0.5); +hold on +er = errorbar([1 2 3 4],data./data,errorVal./data,errorVal./data); +er.Color = [0 0 0]; +er.LineStyle = 'none'; +legend({'data','simulation'}); +ylabel('Relative value'); +xticklabels({'Glycerol','Ethanol','CO2','Biomass'}) +hold off +end \ No newline at end of file diff --git a/code/otherChanges/anaerobicModel.m b/code/otherChanges/anaerobicModel.m index a86c29f3..e6eebec1 100644 --- a/code/otherChanges/anaerobicModel.m +++ b/code/otherChanges/anaerobicModel.m @@ -1,43 +1,73 @@ function model = anaerobicModel(model) % anaerobicModel -% Converts model to anaerobic. +% Constrains yeast-GEM to anaerobic conditions. By default yeast-GEM aims +% to represent aerobic metabolism (particulary with glucose as carbon +% source). Here, various exchange reactions and a few selected +% intracellular reactions are enabled/disabled to yield a model that is +% able to reach similar exchange rates as measured. % -% Inputs: model (struct) aerobic model -% Output: model (struct) anaerobic model -% -% Usage: model = anaerobicModel(model) +% This function was updated as part of release v9.1.0. % +% Input: +% model yeast-GEM model structure, which is aerobic by default +% +% Output: +% model model structure, modified to match anaerobic conditions +% +% Usage: model = anaerobicModel(model) -%1st change: Refit GAM and NGAM to exp. data, change biomass composition -GAM = 30.49; %Data from Nissen et al. 1997 -NGAM = 0; %Refit done in Jouthen et al. 2012 - -model = changeGAM(model,GAM,NGAM); +%% Set environmental conditions +% Remove heme a from the cofactor pseudoreaction (part of biomass) +hemeIdx = find(strcmp(model.mets,'s_3714')); +cofacIdx = find(strcmp(model.rxns,'r_4598')); +model.S(hemeIdx,cofacIdx) = 0; +% Correct H+ +Hc = find(strcmp(model.mets,'s_0794')); +model.S(Hc,cofacIdx) = 0; +model.S(Hc,cofacIdx) = -sum(model.S(:,cofacIdx).*model.metCharges,'omitnan'); -%2nd change: Removes the requirement of heme a, NAD(PH), coenzyme A in the biomass equation -% (not used under anaerobic conditions) -mets = {'s_3714','s_1198','s_1203','s_1207','s_1212','s_0529'}; -[~,met_index] = ismember(mets,model.mets); -model.S(met_index,strcmp(model.rxns,'r_4598')) = 0; +model = changeAminoAcidRatio(model,false); -%3rd change: Changes media to anaerobic (no O2 uptake and allows sterol -% and fatty acid exchanges) +% Change exchange reactions (block O2 uptake and allow sterol and fatty +% acid exchanges, as these are essential supplements for anaerobic growth). model.lb(strcmp(model.rxns,'r_1992')) = 0; %O2 model.lb(strcmp(model.rxns,'r_1757')) = -1000; %ergosterol model.lb(strcmp(model.rxns,'r_1915')) = -1000; %lanosterol -model.lb(strcmp(model.rxns,'r_1994')) = -1000; %palmitoleate model.lb(strcmp(model.rxns,'r_2106')) = -1000; %zymosterol model.lb(strcmp(model.rxns,'r_2134')) = -1000; %14-demethyllanosterol -model.lb(strcmp(model.rxns,'r_2137')) = -1000; %ergosta-5,7,22,24(28)-tetraen-3beta-ol +model.lb(strcmp(model.rxns,'r_1994')) = -1000; %palmitoleate model.lb(strcmp(model.rxns,'r_2189')) = -1000; %oleate +% NEW: remove this due to NADH recycling to ergosterol +model.lb(strcmp(model.rxns,'r_2137')) = 0; %ergosta-5,7,22,24(28)-tetraen-3beta-ol +% Enable uptake of vitamins for NAD(P)H and CoA synthesis +model.lb(strcmp(model.rxns,'r_1967')) = -1000; %nicotinate +model.lb(strcmp(model.rxns,'r_1548')) = -1000; %(R)-pantothenate + +%% Curations that are required to reach correct metabolic phenotypes during +% anaerobic batch growth on minimal glucose media + +% Block MDH2. Involved in growth on two-carbon substrates. Down regulated +% and proteolytically degraded during growth on glucose (Hung et al (2004) +% 10.1074/jbc.M404544200). It is strongly repressed in transcriptome (Tai +% et al (2005) 10.1074/jbc.M410573200) and not detected in proteome +% (Sjöberg et al (2023) 10.1016/j.ymben.2024.01.007). +model.lb(strcmp(model.rxns,'r_0714')) = 0; +model.ub(strcmp(model.rxns,'r_0714')) = 0; + +% Block IDP2. It is strongly repressed in transcriptome (Tai et al (2005) +% 10.1074 /jbc.M410573200) and not detected in proteome (Sjöberg et al +% (2023) 10.1016/j.ymben.2024.01.007). +model.lb(strcmp(model.rxns,'r_0659')) = 0; +model.ub(strcmp(model.rxns,'r_0659')) = 0; + +%% Fumarate reductase is required to recycle FADH2 derived from disulphide +% bound formation by growth in anaerobic conditions through Ero1 (Camarasa +% et al (2007) 10.1002/yea.1467; Kim et al (2018) 10.1038/s41467-018-07285-9). -%4th change: Blocked pathways for proper glycerol production -%Block oxaloacetate-malate shuttle (not present in anaerobic conditions) -model.lb(strcmp(model.rxns,'r_0713')) = 0; %Mithocondria -model.lb(strcmp(model.rxns,'r_0714')) = 0; %Cytoplasm -%Block glycerol dehydroginase (only acts in microaerobic conditions) -model.ub(strcmp(model.rxns,'r_0487')) = 0; -%Block 2-oxoglutarate + L-glutamine -> 2 L-glutamate (alternative pathway) -model.ub(strcmp(model.rxns,'r_0472')) = 0; +FADH2_prod=0.08; +[~,metIdx] = ismember({'s_0689','s_0687','s_0794'},model.mets); % FADH2[c], FAD[c], H+[c] +bioIdx = find(strcmp(model.rxns,'r_4041')); +currCoeff = full(model.S(metIdx,bioIdx)); % Gather the current coefficients +model.S(metIdx,bioIdx) = currCoeff + [FADH2_prod; -FADH2_prod; -2*FADH2_prod]; end diff --git a/code/otherChanges/anaerobicModelOld.m b/code/otherChanges/anaerobicModelOld.m new file mode 100644 index 00000000..9ee5ca42 --- /dev/null +++ b/code/otherChanges/anaerobicModelOld.m @@ -0,0 +1,203 @@ +function model = anaerobicModelOld(model) +% anaerobicModelOld +% This file has been replaced with anaerobicModel since yeast-GEM 9.1.0. +% This function is kept just for comparison purposes. +% +% Inputs: model (struct) aerobic model +% Output: model (struct) anaerobic model +% +% Usage: model = anaerobicModel(model) +% + +%1st change: Refit GAM and NGAM to exp. data, change biomass composition +GAM = 30.49; %Data from Nissen et al. 1997 +P = 0.461; %Data from Nissen et al. 1997 +NGAM = 0; %Refit done in Jouthen et al. 2012 + +model = changeGAM(model,GAM,NGAM); +model = scaleBioMassOld(model,'protein',P,'carbohydrate',false); + +%2nd change: Removes the requirement of heme a, NAD(PH), coenzyme A in the biomass equation +% (not used under anaerobic conditions) +mets = {'s_3714','s_1198','s_1203','s_1207','s_1212','s_0529'}; +[~,met_index] = ismember(mets,model.mets); +model.S(met_index,strcmp(model.rxns,'r_4598')) = 0; + +%3rd change: Changes media to anaerobic (no O2 uptake and allows sterol +% and fatty acid exchanges) +model.lb(strcmp(model.rxns,'r_1992')) = 0; %O2 +model.lb(strcmp(model.rxns,'r_1757')) = -1000; %ergosterol +model.lb(strcmp(model.rxns,'r_1915')) = -1000; %lanosterol +model.lb(strcmp(model.rxns,'r_1994')) = -1000; %palmitoleate +model.lb(strcmp(model.rxns,'r_2106')) = -1000; %zymosterol +model.lb(strcmp(model.rxns,'r_2134')) = -1000; %14-demethyllanosterol +model.lb(strcmp(model.rxns,'r_2137')) = -1000; %ergosta-5,7,22,24(28)-tetraen-3beta-ol +model.lb(strcmp(model.rxns,'r_2189')) = -1000; %oleate + +%4th change: Blocked pathways for proper glycerol production +%Block oxaloacetate-malate shuttle (not present in anaerobic conditions) +model.lb(strcmp(model.rxns,'r_0713')) = 0; %Mithocondria +model.lb(strcmp(model.rxns,'r_0714')) = 0; %Cytoplasm +%Block glycerol dehydroginase (only acts in microaerobic conditions) +model.ub(strcmp(model.rxns,'r_0487')) = 0; +%Block 2-oxoglutarate + L-glutamine -> 2 L-glutamate (alternative pathway) +model.ub(strcmp(model.rxns,'r_0472')) = 0; +end + +function model = scaleBioMassOld(model,component,new_value,balance_out,dispOutput) + % scaleBioMass + % Scales the biomass composition + % + % model (struct) metabolic model in COBRA format + % component (str) name of the component to rescale (e.g. "protein") + % new_value (float) new total fraction for said component + % balance_out (str, opt) if chosen, the name of another component with which + % the model will be balanced out so that the total mass remains = 1 g/gDW + % provide empty string '' if this should not be done + % dispOutput (bool, opt) if output from sumBioMass should be displayed (default = true) + % + % model (struct) modified model + % + % Usage: model = scaleBioMass(model,component,new_value,balance_out,dispOutput) + % + +if nargin < 5 + dispOutput = true; +end +if nargin < 4 + balance_out = ''; +end + +%Measure current composition and rescale: +[~,P,C,R,D,L,I,F] = sumBioMassOld(model,dispOutput); +content_all = {'carbohydrate','protein','lipid','RNA','DNA','ion','cofactor'}; +content_Cap = {'C','P','L','R','D','I','F'}; +pos = strcmp(content_all,component); +old_value = eval(content_Cap{pos}); +f = new_value / old_value; +model = rescalePseudoReaction(model,component,f); + +%Balance out (if desired): +if ~isempty(balance_out) + pos = strcmp(content_all,balance_out); + balance_value = eval(content_Cap{pos}); + f = (balance_value - (new_value - old_value)) / balance_value; + model = rescalePseudoReaction(model,balance_out,f); +end +end + +function [X,P,C,R,D,L,I,F] = sumBioMassOld(model,dispOutput) + % sumBioMass + % Calculates breakdown of biomass + % + % model (struct) Metabolic model in COBRA format + % dispOutput (bool, opt) If output should be displayed (default = true) + % + % X (float) Total biomass fraction [gDW/gDW] + % P (float) Protein fraction [g/gDW] + % C (float) Carbohydrate fraction [g/gDW] + % R (float) RNA fraction [g/gDW] + % D (float) DNA fraction [g/gDW] + % L (float) Lipid fraction [g/gDW] + % F (float) cofactor [g/gDW] + % I (float) ion [g/gDW] + % + % Usage: [X,P,C,R,D,L,I,F] = sumBioMass(model,dispOutput) + % + % Function adapted from SLIMEr: https://github.com/SysBioChalmers/SLIMEr + % + +if nargin < 2 + dispOutput = true; +end + +%Load original biomass component MWs: +%TODO: compute MW automatically from chemical formulas (check that all components have them first) +fid = fopen('../../data/physiology/biomassComposition_Forster2003.tsv'); +Forster2003 = textscan(fid,'%s %s %f32 %f32 %s','Delimiter','\t','HeaderLines',1); +data.mets = Forster2003{1}; +data.MWs = double(Forster2003{4}); +fclose(fid); + +%load additional cofactor/ion MWs: +fid = fopen('../../data/physiology/biomassComposition_Cofactor_Ion.tsv'); +CofactorsIons = textscan(fid,'%s %s %f32 %f32 %s %s','Delimiter','\t','HeaderLines',1); +data_new.mets = CofactorsIons{1}; +data_new.MWs = double(CofactorsIons{4}); +fclose(fid); +for i = 1:length(data_new.mets) + if ~ismember(data_new.mets(i),data.mets) + data.mets = [data.mets; data_new.mets(i)]; + data.MWs = [data.MWs; data_new.MWs(i)]; + end +end + +%Get main fractions: +[P,X] = getFraction(model,data,'P',0,dispOutput); +[C,X] = getFraction(model,data,'C',X,dispOutput); +[R,X] = getFraction(model,data,'R',X,dispOutput); +[D,X] = getFraction(model,data,'D',X,dispOutput); +[L,X] = getFraction(model,data,'L',X,dispOutput); +[I,X] = getFraction(model,data,'I',X,dispOutput); +[F,X] = getFraction(model,data,'F',X,dispOutput); + +if dispOutput + disp(['X -> ' num2str(X) ' gDW/gDW']) + % Simulate growth: + sol = solveLP(model,1); + disp(['Growth = ' num2str(sol.f) ' 1/h']) + disp(' ') +end + +end + +%% + +function [F,X] = getFraction(model,data,compType,X,dispOutput) + +%Define pseudoreaction name: +rxnName = [compType ' pseudoreaction']; +rxnName = strrep(rxnName,'P','protein'); +rxnName = strrep(rxnName,'C','carbohydrate'); +rxnName = strrep(rxnName,'N','biomass'); +rxnName = strrep(rxnName,'L','lipid backbone'); +rxnName = strrep(rxnName,'R','RNA'); +rxnName = strrep(rxnName,'D','DNA'); +rxnName = strrep(rxnName,'I','ion'); +rxnName = strrep(rxnName,'F','cofactor'); + +%Add up fraction: +rxnPos = strcmp(model.rxnNames,rxnName); +if ~all(rxnPos==0) + isSub = model.S(:,rxnPos) < 0; %substrates in pseudo-rxn + if strcmp(compType,'L') + F = -sum(model.S(isSub,rxnPos)); %g/gDW + else + F = 0; + %Add up all components: + for i = 1:length(model.mets) + pos = strcmp(data.mets,model.mets{i}); + if isSub(i) && sum(pos) == 1 + if strcmp(compType,'I') || strcmp(compType,'F') + MW = data.MWs(pos); + else + MW = data.MWs(pos)-18; + end + abundance = -model.S(i,rxnPos)*MW/1000; + F = F + abundance; + end + end + end + X = X + F; + + if dispOutput + disp([compType ' -> ' num2str(F) ' g/gDW']) + end +else + if dispOutput + disp([compType ' does not exist ']) + end + F = 0; + X = X + F; +end +end \ No newline at end of file diff --git a/code/otherChanges/changeAminoAcidRatio.m b/code/otherChanges/changeAminoAcidRatio.m new file mode 100644 index 00000000..52ed6cce --- /dev/null +++ b/code/otherChanges/changeAminoAcidRatio.m @@ -0,0 +1,43 @@ +function model = changeAminoAcidRatio(model,aerobic) +% changeAminoAcidRatio +% Updates the amino acid ratio in the biomass equation, based on data by +% Björkeroth et al. (2020, PNAS, doi:10.1073/pnas.1921890117). +% +% Input: +% model (struct) the yeast GEM +% aerobic (logical) true if ratios should be set for aerobic condition, +% false for anaerobic conditions. Default is true. +% +% Output: +% model (struct) the updated yeast GEM +% +% Usage: model = changeAminoAcidRatio(model,aerobic) +% + +if nargin < 2 || isempty(aerobic) + col = 1; +elseif aerobic % First column is aerobic, second column anaerobic + col = 1; +else + col = 2; +end + +funcDir = dbstack('-completenames'); +funcDir = regexprep(funcDir(1).file,[funcDir(1).name '\.m'],''); + +%Load chemostat data: +fid = fopen(fullfile(funcDir,'..','..','data','physiology','aminoacid_Bjorkeroth2020.tsv'),'r'); +data = textscan(fid,'%s %s %s %f %f %f','Delimiter','\t','HeaderLines',1); +tRNAids = [data{2} data{3}]; +aaRatio = [data{5} data{6}]; +fclose(fid); + +aaRatio = aaRatio(:,col); +aaRatio = [-aaRatio; aaRatio]; + +[~, P] = sumBioMass(model,false); +protRxn = find(strcmp(model.rxns,'r_4047')); +[~, tRNAidxs] = ismember(tRNAids,model.mets); +model.S(tRNAidxs,protRxn) = aaRatio; +model = scaleBioMass(model,'protein',P,[],false); +end \ No newline at end of file diff --git a/code/otherChanges/fitGAM.m b/code/otherChanges/fitGAM.m index 40c3f708..f609eef3 100644 --- a/code/otherChanges/fitGAM.m +++ b/code/otherChanges/fitGAM.m @@ -4,8 +4,11 @@ function model = fitGAM(model) +funcDir = dbstack('-completenames'); +funcDir = regexprep(funcDir(1).file,[funcDir(1).name '\.m'],'') + %Load chemostat data: -fid = fopen('../../data/physiology/chemostatData_VanHoek1998.tsv','r'); +fid = fopen(fullfile(funcDir,'..','..','data','physiology','chemostatData_VanHoek1998.tsv'),'r'); exp_data = textscan(fid,'%f32 %f32 %f32 %f32','Delimiter','\t','HeaderLines',1); exp_data = [exp_data{1} exp_data{2} exp_data{3} exp_data{4}]; fclose(fid); diff --git a/code/otherChanges/glycineNitrogenSource.m b/code/otherChanges/glycineNitrogenSource.m new file mode 100644 index 00000000..e333e188 --- /dev/null +++ b/code/otherChanges/glycineNitrogenSource.m @@ -0,0 +1,21 @@ +function model = glycineNitrogenSource(model) +% glycineNitrogenSource +% Converts model to represent glycine as sole nitrogen source: the +% glycine cleavage system is enabled. +% +% Inputs: model (struct) unmodified model +% Output: model (struct) glycine model +% +% Usage: model = glycineNitrogenSource(model) + +% Glycine cleavage is only active when glycine is used as sole nitrogen +% source. See doi:10.1111/j.1567-1364.2002.tb00069.x; +% doi:10.1074/jbc.274.15.10523; doi:10.1128/EC.2.5.827-829.2003 +model.ub(strcmp(model.rxns,'r_0501'))=0; %glycine cleavage, mitochondrion +model.lb(strcmp(model.rxns,'r_0501'))=1000; +model.ub(strcmp(model.rxns,'r_0507'))=0; %glycine cleavage complex (lipoylprotein), mitochondrion +model.lb(strcmp(model.rxns,'r_0507'))=1000; +model.ub(strcmp(model.rxns,'r_0509'))=0; %glycine cleavage complex (lipoamide), mitochondrion +model.lb(strcmp(model.rxns,'r_0509'))=1000; +end + \ No newline at end of file diff --git a/code/otherChanges/nitrogenLimitation.m b/code/otherChanges/nitrogenLimitation.m new file mode 100644 index 00000000..4a235209 --- /dev/null +++ b/code/otherChanges/nitrogenLimitation.m @@ -0,0 +1,16 @@ +function model = nitrogenLimitation(model) +% nitrogenLimitation +% Converts model to represents nitrogen-limiting environmental conditions +% +% Inputs: model (struct) unmodified model +% Output: model (struct) nitrogen-limitation model +% +% Usage: model = nitrogenLimitation(model) + +% Glutamine synthase is repressed when nitrogen is in excess. See doi:10.1128/EC.2.5.827-829.2003 +model.ub(strcmp(model.rxns,'r_0472'))=1000; +% Glycine cleavage system is repressed when nitrogen (non-glycine) is in excess +model.lb(strcmp(model.rxns,'r_0501'))=1000; %glycine cleavage, mitochondrion +model.lb(strcmp(model.rxns,'r_0507'))=1000; %glycine cleavage complex (lipoylprotein), mitochondrion +model.lb(strcmp(model.rxns,'r_0509'))=1000; %glycine cleavage complex (lipoamide), mitochondrion +end diff --git a/code/otherChanges/rescalePseudoReaction.m b/code/otherChanges/rescalePseudoReaction.m index 8937b03e..b1ab2920 100644 --- a/code/otherChanges/rescalePseudoReaction.m +++ b/code/otherChanges/rescalePseudoReaction.m @@ -1,15 +1,15 @@ function model = rescalePseudoReaction(model,metName,f) - % rescalePseudoReaction - % Rescales a specific pseudoreaction by a given factor - % - % model (struct) the yeast GEM - % metName (str) name of the component to rescale (e.g. "protein") - % f (float) fraction to use for rescaling - % - % model (struct) the (rescaled) yeast GEM - % - % Usage: model = rescalePseudoReaction(model,metName,f) - % +% rescalePseudoReaction +% Rescales a specific pseudoreaction by a given factor +% +% model (struct) the yeast GEM +% metName (str) name of the component to rescale (e.g. "protein") +% f (float) fraction to use for rescaling +% +% model (struct) the (rescaled) yeast GEM +% +% Usage: model = rescalePseudoReaction(model,metName,f) +% if strcmp(metName,'lipid') model = rescalePseudoReaction(model,'lipid backbone',f); @@ -24,6 +24,9 @@ model.S(i,rxnPos) = f*S_ir; end end + % Correct H+ + Hc = find(strcmp(model.mets,'s_0794')); + model.S(Hc,rxnPos) = 0; + model.S(Hc,rxnPos) = -sum(model.S(:,rxnPos).*model.metCharges,'omitnan'); end - end diff --git a/code/otherChanges/scaleBioMass.m b/code/otherChanges/scaleBioMass.m index dab4282a..ac37a75d 100644 --- a/code/otherChanges/scaleBioMass.m +++ b/code/otherChanges/scaleBioMass.m @@ -28,20 +28,21 @@ end %Measure current composition and rescale: -[~,P,C,R,D,L,I,F] = sumBioMass(model,dispOutput); -content_all = {'carbohydrate','protein','lipid','RNA','DNA','ion','cofactor'}; -content_Cap = {'C','P','L','R','D','I','F'}; +[X,P,C,R,D,L,I,F] = sumBioMass(model,false); +content_all = {'biomass','carbohydrate','protein','lipid','RNA','DNA','ion','cofactor'}; +content_Cap = {'X','C','P','L','R','D','I','F'}; pos = strcmp(content_all,component); old_value = eval(content_Cap{pos}); f = new_value / old_value; model = rescalePseudoReaction(model,component,f); -X = sumBioMass(model,false); %Balance out (if desired): if ~isempty(balance_out) + X = sumBioMass(model,false); pos = strcmp(content_all,balance_out); balance_value = eval(content_Cap{pos}); f = (balance_value + (1-X)) / balance_value; model = rescalePseudoReaction(model,balance_out,f); end +sumBioMass(model,dispOutput); end diff --git a/code/otherChanges/sumBioMass.m b/code/otherChanges/sumBioMass.m index f8daeb12..ff975274 100644 --- a/code/otherChanges/sumBioMass.m +++ b/code/otherChanges/sumBioMass.m @@ -23,35 +23,14 @@ dispOutput = true; end -%Load original biomass component MWs: -%TODO: compute MW automatically from chemical formulas (check that all components have them first) -fid = fopen('../../data/physiology/biomassComposition_Forster2003.tsv'); -Forster2003 = textscan(fid,'%s %s %f32 %f32 %s','Delimiter','\t','HeaderLines',1); -data.mets = Forster2003{1}; -data.MWs = double(Forster2003{4}); -fclose(fid); - -%load additional cofactor/ion MWs: -fid = fopen('../../data/physiology/biomassComposition_Cofactor_Ion.tsv'); -CofactorsIons = textscan(fid,'%s %s %f32 %f32 %s %s','Delimiter','\t','HeaderLines',1); -data_new.mets = CofactorsIons{1}; -data_new.MWs = double(CofactorsIons{4}); -fclose(fid); -for i = 1:length(data_new.mets) - if ~ismember(data_new.mets(i),data.mets) - data.mets = [data.mets; data_new.mets(i)]; - data.MWs = [data.MWs; data_new.MWs(i)]; - end -end - %Get main fractions: -[P,X] = getFraction(model,data,'P',0,dispOutput); -[C,X] = getFraction(model,data,'C',X,dispOutput); -[R,X] = getFraction(model,data,'R',X,dispOutput); -[D,X] = getFraction(model,data,'D',X,dispOutput); -[L,X] = getFraction(model,data,'L',X,dispOutput); -[I,X] = getFraction(model,data,'I',X,dispOutput); -[F,X] = getFraction(model,data,'F',X,dispOutput); +[P,X] = getFraction(model,'P',0,dispOutput); +[C,X] = getFraction(model,'C',X,dispOutput); +[R,X] = getFraction(model,'R',X,dispOutput); +[D,X] = getFraction(model,'D',X,dispOutput); +[L,X] = getFraction(model,'L',X,dispOutput); +[I,X] = getFraction(model,'I',X,dispOutput); +[F,X] = getFraction(model,'F',X,dispOutput); if dispOutput disp(['X -> ' num2str(X) ' gDW/gDW']) @@ -60,12 +39,10 @@ disp(['Growth = ' num2str(sol.f) ' 1/h']) disp(' ') end - end %% - -function [F,X] = getFraction(model,data,compType,X,dispOutput) +function [F,X] = getFraction(model,compType,X,dispOutput) %Define pseudoreaction name: rxnName = [compType ' pseudoreaction']; @@ -80,37 +57,69 @@ %Add up fraction: rxnPos = strcmp(model.rxnNames,rxnName); -if ~all(rxnPos==0) - isSub = model.S(:,rxnPos) < 0; %substrates in pseudo-rxn - if strcmp(compType,'L') - F = -sum(model.S(isSub,rxnPos)); %g/gDW - else - F = 0; - %Add up all components: - for i = 1:length(model.mets) - pos = strcmp(data.mets,model.mets{i}); - if isSub(i) && sum(pos) == 1 - if strcmp(compType,'I') || strcmp(compType,'F') - MW = data.MWs(pos); - else - MW = data.MWs(pos)-18; - end - abundance = -model.S(i,rxnPos)*MW/1000; - F = F + abundance; - end - end - end - X = X + F; - - if dispOutput - disp([compType ' -> ' num2str(F) ' g/gDW']) - end -else +if isempty(rxnPos) if dispOutput disp([compType ' does not exist ']) end F = 0; - X = X + F; +else + isSub = find(model.S(:,rxnPos)<0); % Substrates in pseudoreaction + if strcmp(compType,'L') % Lipid already has g/gDW as unit + F = full(-sum(model.S(isSub,rxnPos))); + else + formulas = model.metFormulas(isSub); + MWs = zeros(numel(formulas),1); + for i = 1:numel(formulas) + MWs(i) = parseChemicalFormula(formulas{i}); + end + zeroMW = MWs == 0; + if any(zeroMW) + error('Biomass metabolite %s has an empty metFormula field.', model.mets{isSub(zeroMW)}) + end + switch compType + case 'P' + % Two protons have to be removed from the charged-tRNA + % formulas that are in the model + MWs = MWs - 2.016; + case {'R','D'} + % H2O has to be removed to represent polymerization + MWs = MWs - 18.015; + end + F = full(-sum(model.S(isSub,rxnPos).*MWs)/1000); + end end +X = X + F; + +if dispOutput + disp([compType ' -> ' num2str(F) ' g/gDW']) +end +end + +function molecularWeight = parseChemicalFormula(formula) + % Split formula in elements and coefficients + tokens = regexp(formula, '([A-Z][a-z]*)(\d*)', 'tokens'); + tokensMatrix = vertcat(tokens{:}); + tokensMatrix(cellfun(@isempty,tokensMatrix(:,2)),2) = {'1'}; + elements = tokensMatrix(:, 1); + counts = str2double(tokensMatrix(:, 2)); + %Weight of elements + elem = {'C', 12.01; ... + 'H', 1.008; ... + 'N', 14.007; ... + 'O', 15.999; ... + 'P', 30.974; ... + 'S', 32.06; ... + 'R', 0; ... + 'Fe', 55.845; ... + 'K', 39.098; ... + 'Na', 22.99; ... + 'Cl', 35.45; ... + 'Mn', 54.938; ... + 'Zn', 65.38; ... + 'Ca', 40.078; ... + 'Mg', 24.305; ... + 'Cu', 63.546}; + [~,elemMatch] = ismember(elements,elem(:,1)); + molecularWeight = sum(counts .* transpose([elem{elemMatch,2}]),'all'); end diff --git a/code/saveYeastModel.m b/code/saveYeastModel.m index aa523855..84330ca4 100644 --- a/code/saveYeastModel.m +++ b/code/saveYeastModel.m @@ -128,7 +128,7 @@ function saveYeastModel(model,upDATE,allowNoGrowth,binaryFiles) %% function checkGrowth(model,condition,allowNoGrowth) -%Function that checks if the model can grow or not using COBRA under a +%Function that checks if the model can grow or not using RAVEN under a %given condition (aerobic or anaerobic). Will either return warnings or %errors depending on allowNoGrowth. @@ -145,9 +145,9 @@ function checkGrowth(model,condition,allowNoGrowth) condition ' conditions. Please ensure the model can grow']; end catch - dispText = ['The model yields an infeasible simulation using COBRA ' ... + dispText = ['The model yields an infeasible simulation using RAVEN ' ... 'under ' condition ' conditions. Please ensure the model ' ... - 'can be simulated with COBRA']; + 'can be simulated with RAVEN']; end if exist('dispText','var') diff --git a/data/databases/model_metDeltaG.csv b/data/databases/model_metDeltaG.csv index ebe81da5..9c57a7f6 100644 --- a/data/databases/model_metDeltaG.csv +++ b/data/databases/model_metDeltaG.csv @@ -1378,7 +1378,6 @@ s_2882,-36.15 s_2883,-5.76 s_2884,-368.48 s_2885,-320.52 -s_2886,-370.03 s_2887,-322.07 s_2888,-274.11 s_2889,-68.4 @@ -2276,9 +2275,7 @@ s_3780,-101.44 s_3781,-291.47 s_3782,10000000 s_3783,10000000 -s_3784,10000000 s_3785,-15.24 -s_3786,10000000 s_3787,467.11 s_3788,467.11 s_3789,54.52 @@ -2309,31 +2306,19 @@ s_3815,-61.6 s_3816,10000000 s_3817,10000000 s_3818,147.48 -s_3819,10000000 -s_3820,109.37 -s_3821,10000000 s_3822,10000000 s_3823,10000000 s_3826,10000000 s_3827,10000000 s_3828,113.67 s_3829,103.13 -s_3830,10000000 s_3831,-70.58 -s_3832,10000000 -s_3833,10000000 -s_3834,10000000 -s_3835,10000000 -s_3836,10000000 s_3837,10000000 s_3838,-37.83 s_3839,-39.05 s_3840,32.76 s_3841,-151.3 -s_3842,10000000 s_3843,-70.58 -s_3844,10000000 -s_3845,10000000 s_3846,-139.59 s_3847,-126.95 s_3848,-139.59 @@ -2341,8 +2326,6 @@ s_3849,-155.26 s_3850,-126.95 s_3851,31.01 s_3852,-307.29 -s_3853,10000000 -s_3854,10000000 s_3855,-45.17 s_3856,10000000 s_3857,10000000 @@ -2353,8 +2336,6 @@ s_3861,-89.12 s_3862,-101.44 s_3863,-438.52 s_3864,-48.81 -s_3865,201.61 -s_3866,201.61 s_3867,80.19 s_3868,125.69 s_3871,-35.96 @@ -2362,16 +2343,12 @@ s_3872,26.14 s_3873,57.55 s_3874,-4.56 s_3875,-161.75 -s_3876,10000000 -s_3877,10000000 s_3878,10000000 s_3879,10000000 s_3880,10000000 s_3881,-564.41 s_3882,10000000 s_3883,-356.59 -s_3884,10000000 -s_3885,10000000 s_3887,10000000 s_3888,83.01 s_3889,10000000 @@ -2385,31 +2362,19 @@ s_3896,10000000 s_3897,-413.18 s_3898,-324.48 s_3899,-117.34 -s_3900,10000000 -s_3901,-117.34 -s_3902,10000000 s_3903,-233.3 s_3904,-55.99 s_3905,-73.97 s_3906,10000000 -s_3907,10000000 -s_3908,10000000 -s_3909,10000000 s_3910,10000000 s_3911,232.67 s_3912,10000000 s_3913,21.56 s_3914,-26.8 -s_3915,62.4 -s_3916,-33.67 -s_3917,10000000 -s_3918,10000000 s_3923,-129.66 s_3924,-129.66 s_3925,-21.63 s_3926,-31.38 -s_3927,10000000 -s_3928,10000000 s_3929,10000000 s_3930,10000000 s_3931,-64.08 @@ -2418,17 +2383,8 @@ s_3933,-101.44 s_3934,10000000 s_3935,0.84 s_3936,-45.17 -s_3937,10000000 -s_3938,10000000 -s_3939,10000000 -s_3940,10000000 -s_3941,10000000 s_3942,-614.38 s_3943,-184.19 -s_3944,10000000 -s_3945,10000000 -s_3946,10000000 -s_3947,10000000 s_3948,-325.37 s_3949,-101.44 s_3950,-324.48 @@ -2463,8 +2419,6 @@ s_3981,157.83 s_3982,95.19 s_3983,279.11 s_3984,216.48 -s_3985,10000000 -s_3986,10000000 s_3987,-356.59 s_3988,284.12 s_3989,-146.42 @@ -2482,11 +2436,6 @@ s_4000,10000000 s_4001,10000000 s_4002,10000000 s_4003,10000000 -s_4004,10000000 -s_4005,117.75 -s_4006,10000000 -s_4007,10000000 -s_4008,10000000 s_4009,39.02 s_4010,-112.47 s_4011,-117.23 @@ -2506,12 +2455,7 @@ s_4024,10000000 s_4025,10000000 s_4026,10000000 s_4027,10000000 -s_4028,10000000 -s_4029,10000000 -s_4030,10000000 s_4031,-45.17 -s_4032,10000000 -s_4033,10000000 s_4034,-52.05 s_4035,-52.05 s_4036,-52.05 @@ -2737,8 +2681,6 @@ s_4261,NaN s_4262,NaN s_4263,10000000 s_4264,-79.97 -s_4265,10000000 -s_4266,10000000 s_4267,-235.6 s_4268,-235.6 s_4269,-229 @@ -2787,8 +2729,6 @@ s_4311,2.94 s_4312,NaN s_4313,-633.42 s_4314,-424.2 -s_4315,-361.56 -s_4316,-266.32 s_4317,-657.7 s_4318,-524.57 s_4319,-316.75 @@ -2805,3 +2745,5 @@ s_4329,-450.64 s_4330,-659.91 s_4331,-63.35 s_4332,10000000 +s_4333,-178.74 +s_4334,NaN diff --git a/data/databases/model_rxnDeltaG.csv b/data/databases/model_rxnDeltaG.csv index 13d53174..f7eee2c8 100644 --- a/data/databases/model_rxnDeltaG.csv +++ b/data/databases/model_rxnDeltaG.csv @@ -681,7 +681,6 @@ r_0883,10000000 r_0884,-10.98 r_0885,-2.83 r_0886,-16.73 -r_0887,-16.72 r_0888,0 r_0889,6.91 r_0890,1.04 @@ -3536,7 +3535,6 @@ r_4169,-2.32 r_4170,10000000 r_4171,-4.76 r_4172,10000000 -r_4173,10000000 r_4174,0 r_4175,3.27 r_4176,3.26 @@ -3555,28 +3553,22 @@ r_4189,0.37 r_4190,10000000 r_4191,7.11 r_4192,10000000 -r_4193,10000000 r_4194,10000000 r_4195,10000000 r_4196,10000000 r_4197,10000000 r_4198,9.76 -r_4199,10000000 -r_4200,10000000 -r_4201,10000000 r_4202,10000000 r_4203,2.99 r_4204,-1.2 r_4205,-9.93 r_4206,-0.74 -r_4207,10000000 r_4208,-1.46 r_4209,-0.4 r_4210,3.55 r_4211,-48 r_4212,-48.6 r_4214,4.56 -r_4215,10000000 r_4216,10000000 r_4217,-46.29 r_4218,10000000 @@ -3586,42 +3578,33 @@ r_4221,3.17 r_4222,-15.22 r_4223,-6.84 r_4224,10000000 -r_4225,-2.69 r_4226,-4.11 r_4227,-5.11 r_4228,-5.11 r_4230,5.11 r_4231,-5.11 r_4232,-16 -r_4233,10000000 r_4234,10000000 r_4236,16.42 r_4237,10000000 r_4238,10000000 -r_4239,10000000 r_4241,10000000 r_4242,10000000 r_4243,10000000 r_4244,10000000 r_4245,-3.02 -r_4246,10000000 r_4247,-12.04 r_4248,-7.9 r_4249,10000000 r_4250,10000000 -r_4251,10000000 -r_4252,10000000 r_4253,10000000 r_4254,10000000 r_4255,10000000 -r_4256,-5.03 -r_4258,10000000 r_4260,-5.49 r_4261,-6.17 r_4262,1.42 r_4263,-0.19 r_4264,13.92 -r_4265,10000000 r_4266,-23.79 r_4267,-27.87 r_4268,-27.87 @@ -3633,11 +3616,7 @@ r_4273,10000000 r_4274,-6.12 r_4275,-72.46 r_4276,-56.75 -r_4277,10000000 -r_4278,10000000 r_4279,-5.68 -r_4280,10000000 -r_4281,10000000 r_4282,-16.73 r_4283,-15.23 r_4284,-15.23 @@ -3662,7 +3641,6 @@ r_4304,10000000 r_4305,-10.6 r_4306,-10.61 r_4307,-10.61 -r_4308,10000000 r_4309,-2.55 r_4310,10000000 r_4311,2.77 @@ -3677,9 +3655,6 @@ r_4319,10000000 r_4320,10000000 r_4321,10000000 r_4322,10000000 -r_4323,10000000 -r_4324,10000000 -r_4325,10000000 r_4326,-21.6 r_4327,10000000 r_4328,10000000 @@ -3694,7 +3669,6 @@ r_4336,-5.5 r_4337,10000000 r_4338,10000000 r_4339,10000000 -r_4340,10000000 r_4341,4.96 r_4342,7.11 r_4343,-3.41 @@ -3921,7 +3895,6 @@ r_4563,10000000 r_4564,10000000 r_4565,10000000 r_4567,10000000 -r_4568,10000000 r_4569,-8.38 r_4570,5.82 r_4571,10000000 @@ -4051,12 +4024,9 @@ r_4700,0 r_4701,-2.94 r_4702,-14.95 r_4703,-12.45 -r_4704,NaN r_4705,0 -r_4706,NaN r_4707,-160.69 r_4708,-51.44 -r_4709,NaN r_4710,NaN r_4711,NaN r_4712,NaN @@ -4106,7 +4076,6 @@ r_4755,NaN r_4756,NaN r_4757,NaN r_4758,NaN -r_4759,NaN r_4760,NaN r_4761,NaN r_4762,NaN @@ -4130,3 +4099,5 @@ r_4779,0 r_4780,NaN r_4781,NaN r_4782,NaN +r_4783,NaN +r_4784,NaN diff --git a/data/physiology/aminoAcid_Bjorkeroth2020.tsv b/data/physiology/aminoAcid_Bjorkeroth2020.tsv new file mode 100644 index 00000000..c4532df2 --- /dev/null +++ b/data/physiology/aminoAcid_Bjorkeroth2020.tsv @@ -0,0 +1,21 @@ + aerobic anaerobic +alanine s_0404 s_1582 89.09 8.297254781 8.333020372 +cysteine s_0542 s_1589 121.16 0.896197612 0.886731932 +aspartic acid s_0432 s_1587 133.11 5.735167195 5.730817148 +glutamic acid s_0748 s_1591 147.13 7.074407898 6.923392022 +phenylalanine s_1314 s_1604 165.19 3.979875681 4.024368832 +glycine s_0757 s_1593 75.07 6.770461891 6.926799575 +histidine s_0832 s_1594 155.15 1.993972898 2.039890323 +isoleucine s_0847 s_1596 131.17 6.334796606 6.307298159 +lysine s_1099 s_1600 146.19 7.859720537 7.796491526 +leucine s_1077 s_1598 131.17 8.650075568 8.60982583 +methionine s_1148 s_1602 149.21 1.944590197 1.865411506 +asparagine s_0430 s_1585 132.12 4.568570566 4.578884297 +proline s_1379 s_1606 115.13 4.29066644 4.352671224 +glutamine s_0747 s_1590 146.14 3.368190574 3.360141247 +arginine s_0428 s_1583 174.2 4.636052043 4.560526314 +serine s_1428 s_1607 105.09 6.626740895 6.612652098 +threonine s_1491 s_1608 119.12 5.611403461 5.608015395 +valine s_1561 s_1614 117.15 7.506698673 7.527134958 +tryptophan s_1527 s_1610 204.23 0.920304475 0.932103986 +tyrosine s_1533 s_1612 181.19 2.935483817 3.023817051 diff --git a/data/physiology/biomassComposition_Forster2003.tsv b/data/physiology/biomassComposition_Forster2003.tsv index 20231d00..48a17fd3 100644 --- a/data/physiology/biomassComposition_Forster2003.tsv +++ b/data/physiology/biomassComposition_Forster2003.tsv @@ -36,3 +36,4 @@ s_1533 tyrosine 0.102 181.19 protein s_1545 UMP 0.0599 324.18 RNA s_1561 valine 0.2646 117.15 protein s_3714 heme a 0.000001 852.83 other +s_0794 H+ 1.0008 diff --git a/data/physiology/flux_data_anaerobic.tsv b/data/physiology/flux_data_anaerobic.tsv new file mode 100644 index 00000000..ba9166c4 --- /dev/null +++ b/data/physiology/flux_data_anaerobic.tsv @@ -0,0 +1,126 @@ +GlcV GlcV 6.3 6.58 100 Jouhten2008 r_1714 D-glucose exchange D-glucose[extracellular] <=> +G6P F6P 88 88 88 Jouhten2008 r_0467 glucose-6-phosphate isomerase D-glucose 6-phosphate[cytoplasm] <=> D-fructose 6-phosphate[cytoplasm] +F6P G3P 91 91 91 Jouhten2008 r_0450 fructose-bisphosphate aldolase D-fructose 1,6-bisphosphate[cytoplasm] <=> dihydroxyacetone phosphate[cytoplasm] + glyceraldehyde 3-phosphate[cytoplasm] +G3P Pep 163 163 163 Jouhten2008 r_0366 enolase 2-phospho-D-glyceric acid[cytoplasm] <=> H2O[cytoplasm] + phosphoenolpyruvate[cytoplasm] +Pyr OaaCit 5 5 5 Jouhten2008 r_0958 pyruvate carboxylase ATP[cytoplasm] + bicarbonate[cytoplasm] + pyruvate[cytoplasm] -> ADP[cytoplasm] + H+[cytoplasm] + oxaloacetate[cytoplasm] + phosphate[cytoplasm] +G3p Glycerol 17 17 17 Jouhten2008 r_0489 glycerol-3-phosphatase glycerol 3-phosphate[cytoplasm] + H2O[cytoplasm] -> glycerol[cytoplasm] + phosphate[cytoplasm] +G6P P5P 5 5 5 Jouhten2008 r_0466 glucose 6-phosphate dehydrogenase D-glucose 6-phosphate[cytoplasm] + NADP(+)[cytoplasm] -> 6-O-phosphono-D-glucono-1,5-lactone[cytoplasm] + H+[cytoplasm] + NADPH[cytoplasm] +P5P+E4P F6P+G3P 1 1 1 Jouhten2008 r_1049 transketolase 1 D-xylulose 5-phosphate[cytoplasm] + ribose-5-phosphate[cytoplasm] <=> glyceraldehyde 3-phosphate[cytoplasm] + sedoheptulose 7-phosphate[cytoplasm] +G3P+S7P F6p+E4P 2 2 2 Jouhten2008 r_1048 transaldolase glyceraldehyde 3-phosphate[cytoplasm] + sedoheptulose 7-phosphate[cytoplasm] <=> D-erythrose 4-phosphate[cytoplasm] + D-fructose 6-phosphate[cytoplasm] +PyrCyt AcO 149 148 148.5 Jouhten2008 r_0959 pyruvate decarboxylase H+[cytoplasm] + pyruvate[cytoplasm] -> acetaldehyde[cytoplasm] + carbon dioxide[cytoplasm] +AcO Ethanol 147 147 147 Jouhten2008 r_2115 alcohol dehydrogenase, (acetaldehyde to ethanol) acetaldehyde[cytoplasm] + H+[cytoplasm] + NADH[cytoplasm] -> ethanol[cytoplasm] + NAD[cytoplasm] +Ethanol Ethanolext 147 147 147 Jouhten2008 r_1761 ethanol exchange ethanol[extracellular] -> +AcO Acetate 2 2 2 Jouhten2008 r_0173 +Acetate Acetateext 0 0 0 Jouhten2008 r_1634 acetate exchange acetate[extracellular] -> +Pep PyrCyt 162 162 162 Jouhten2008 r_0962 pyruvate kinase ADP[cytoplasm] + H+[cytoplasm] + phosphoenolpyruvate[cytoplasm] -> ATP[cytoplasm] + pyruvate[cytoplasm] +PyrCyt OaaCyt 5 5 5 Jouhten2008 r_0958 pyruvate carboxylase ATP[cytoplasm] + bicarbonate[cytoplasm] + pyruvate[cytoplasm] -> ADP[cytoplasm] + H+[cytoplasm] + oxaloacetate[cytoplasm] + phosphate[cytoplasm] +OaaCyt+MalMit OaaMit+MalCyt 3 3 3 Jouhten2008 r_4783 oxaloacetate/sulphate antiport, mitochondrial oxaloacetate[cytoplasm] + sulphate[mitochondrion] <=> oxaloacetate[mitochondrion] + sulphate[cytoplasm] +OaaMit+MalMit Cit 3 3 3 Jouhten2008 r_0300 citrate synthase acetyl-CoA[mitochondrion] + H2O[mitochondrion] + oxaloacetate[mitochondrion] -> citrate[mitochondrion] + coenzyme A[mitochondrion] + H+[mitochondrion] +PyrMit AcCCoAMit 4 4 4 Jouhten2008 r_0113 acetyl-CoA synthetase acetate[mitochondrion] + ATP[mitochondrion] + coenzyme A[mitochondrion] -> acetyl-CoA[mitochondrion] + AMP[mitochondrion] + diphosphate[mitochondrion] +PyrCyt PyrMit 8 8 8 Jouhten2008 r_2034 pyruvate transport H+[cytoplasm] + pyruvate[cytoplasm] -> H+[mitochondrion] + pyruvate[mitochondrion] +Cit Oga 3 3 3 Jouhten2008 r_0658 isocitrate dehydrogenase (NAD+) isocitrate[mitochondrion] + NAD[mitochondrion] -> 2-oxoglutarate[mitochondrion] + carbon dioxide[mitochondrion] + NADH[mitochondrion] +mu mu 0.1 0.1 1.552795031 Jouhten2008 r_2111 growth biomass[cytoplasm] -> +Glucose uptake (mmol/gDW/h) 17.8 100 Celton2012 r_1714 D-glucose exchange D-glucose[extracellular] <=> +Glycolysis 84.7 Celton2012 r_0467 glucose-6-phosphate isomerase D-glucose 6-phosphate[cytoplasm] <=> D-fructose 6-phosphate[cytoplasm] +PPP 11.4 Celton2012 r_0466 glucose 6-phosphate dehydrogenase D-glucose 6-phosphate[cytoplasm] + NADP(+)[cytoplasm] -> 6-O-phosphono-D-glucono-1,5-lactone[cytoplasm] + H+[cytoplasm] + NADPH[cytoplasm] +Transketolase 5.6 Celton2012 r_1049 transketolase 1 D-xylulose 5-phosphate[cytoplasm] + ribose-5-phosphate[cytoplasm] <=> glyceraldehyde 3-phosphate[cytoplasm] + sedoheptulose 7-phosphate[cytoplasm] +Pyruvate decarboxylase 164.3 Celton2012 r_0959 pyruvate decarboxylase H+[cytoplasm] + pyruvate[cytoplasm] -> acetaldehyde[cytoplasm] + carbon dioxide[cytoplasm] +Pyruvate carboxylase 4.2 Celton2012 r_0958 pyruvate carboxylase ATP[cytoplasm] + bicarbonate[cytoplasm] + pyruvate[cytoplasm] -> ADP[cytoplasm] + H+[cytoplasm] + oxaloacetate[cytoplasm] + phosphate[cytoplasm] +Import of oxaloacetate into the mitochondria 3.4 Celton2012 r_4783 oxaloacetate/sulphate antiport, mitochondrial oxaloacetate[cytoplasm] + sulphate[mitochondrion] <=> oxaloacetate[mitochondrion] + sulphate[cytoplasm] +Acetaldehyde dehydrogenase 2.4 Celton2012 r_0173 +Acetyl-CoA synthetase 0.3 Celton2012 r_0113 acetyl-CoA synthetase acetate[mitochondrion] + ATP[mitochondrion] + coenzyme A[mitochondrion] -> acetyl-CoA[mitochondrion] + AMP[mitochondrion] + diphosphate[mitochondrion] +Ethanol production 161.9 Celton2012 r_1761 ethanol exchange ethanol[extracellular] -> +Glycerol production 17.8 Celton2012 r_1808 glycerol exchange glycerol[extracellular] -> +Acetate production 2.1 Celton2012 r_1634 acetate exchange acetate[extracellular] -> +Succinate production 0.3 Celton2012 r_2056 succinate exchange succinate[extracellular] -> +mu 0.4 2.247191011 Celton2012 r_2111 growth biomass[cytoplasm] -> +Glucose Glucose 13.49 13.49 100 Wasylenko2014 r_1714 D-glucose exchange D-glucose[extracellular] <=> +mu mu 0.23 1.704966642 Wasylenko2014 r_2111 growth biomass[cytoplasm] -> +G6P Ru5P 0.68 5.040770941 Wasylenko2014 r_0466 glucose 6-phosphate dehydrogenase D-glucose 6-phosphate[cytoplasm] + NADP(+)[cytoplasm] -> 6-O-phosphono-D-glucono-1,5-lactone[cytoplasm] + H+[cytoplasm] + NADPH[cytoplasm] +G6P F6P 12.42 92.06819867 Wasylenko2014 r_0467 glucose-6-phosphate isomerase D-glucose 6-phosphate[cytoplasm] <=> D-fructose 6-phosphate[cytoplasm] +F6P FBP 12.62 93.55077835 Wasylenko2014 r_0886 phosphofructokinase ATP[cytoplasm] + D-fructose 6-phosphate[cytoplasm] -> ADP[cytoplasm] + D-fructose 1,6-bisphosphate[cytoplasm] + H+[cytoplasm] +Ru5P X5P 0.38 2.816901408 Wasylenko2014 r_0984 ribulose 5-phosphate 3-epimerase D-ribulose 5-phosphate[cytoplasm] <=> D-xylulose 5-phosphate[cytoplasm] +Ru5P R5P 0.3 2.223869533 Wasylenko2014 r_0982 ribose-5-phosphate isomerase D-ribulose 5-phosphate[cytoplasm] <=> ribose-5-phosphate[cytoplasm] +FBP DHAP+GAP 12.62 93.55077835 Wasylenko2014 r_0450 fructose-bisphosphate aldolase D-fructose 1,6-bisphosphate[cytoplasm] <=> dihydroxyacetone phosphate[cytoplasm] + glyceraldehyde 3-phosphate[cytoplasm] +DHAP Glyc3P 2.99 22.16456635 Wasylenko2014 r_0491 glycerol-3-phosphate dehydrogenase (NAD) dihydroxyacetone phosphate[cytoplasm] + H+[cytoplasm] + NADH[cytoplasm] -> glycerol 3-phosphate[cytoplasm] + NAD[cytoplasm] +Glyc3P Glycerol 2.98 22.09043736 Wasylenko2014 r_0489 glycerol-3-phosphatase glycerol 3-phosphate[cytoplasm] + H2O[cytoplasm] -> glycerol[cytoplasm] + phosphate[cytoplasm] +GAP 3PG 22.42 166.1971831 Wasylenko2014 r_0486 glyceraldehyde-3-phosphate dehydrogenase glyceraldehyde 3-phosphate[cytoplasm] + NAD[cytoplasm] + phosphate[cytoplasm] <=> 1,3-bisphospho-D-glycerate[cytoplasm] + H+[cytoplasm] + NADH[cytoplasm] +3PG Ser 0.07 0.518902891 Wasylenko2014 r_0917 phosphoserine phosphatase (L-serine) 3-phospho-serine[cytoplasm] + H2O[cytoplasm] -> L-serine[cytoplasm] + phosphate[cytoplasm] +Ser Gly+C1 0.07 0.518902891 Wasylenko2014 r_0502 glycine hydroxymethyltransferase L-serine[cytoplasm] + THF[cytoplasm] <=> 5,10-methylenetetrahydrofolate[cytoplasm] + H2O[cytoplasm] + L-glycine[cytoplasm] +Thr Gly+AcCHO 0.14 1.037805782 Wasylenko2014 r_1040 threonine aldolase L-threonine[cytoplasm] -> acetaldehyde[cytoplasm] + L-glycine[cytoplasm] +3PG PEP 22.35 165.6782802 Wasylenko2014 r_0366 enolase 2-phospho-D-glyceric acid[cytoplasm] <=> H2O[cytoplasm] + phosphoenolpyruvate[cytoplasm] +PEP PyrCyt 22.23 164.7887324 Wasylenko2014 r_0962 pyruvate kinase ADP[cytoplasm] + H+[cytoplasm] + phosphoenolpyruvate[cytoplasm] -> ATP[cytoplasm] + pyruvate[cytoplasm] +PyrCyt AcCHO+CO2 21.24 157.4499629 Wasylenko2014 r_0959 pyruvate decarboxylase H+[cytoplasm] + pyruvate[cytoplasm] -> acetaldehyde[cytoplasm] + carbon dioxide[cytoplasm] +PyrCyt OaaCyt 0.77 5.707931801 Wasylenko2014 r_0958 pyruvate carboxylase ATP[cytoplasm] + bicarbonate[cytoplasm] + pyruvate[cytoplasm] -> ADP[cytoplasm] + H+[cytoplasm] + oxaloacetate[cytoplasm] + phosphate[cytoplasm] +PyrCyt PyrMit 0.2 1.482579689 Wasylenko2014 r_2034 pyruvate transport H+[cytoplasm] + pyruvate[cytoplasm] -> H+[mitochondrion] + pyruvate[mitochondrion] +AcCHO Ethanol 20.64 153.0022239 Wasylenko2014 r_2115 alcohol dehydrogenase, (acetaldehyde to ethanol) acetaldehyde[cytoplasm] + H+[cytoplasm] + NADH[cytoplasm] -> ethanol[cytoplasm] + NAD[cytoplasm] +AcCHO Acetate 0.74 5.485544848 Wasylenko2014 r_0173 +Acetate AcCoaCyt 0.43 3.187546331 Wasylenko2014 r_0113 acetyl-CoA synthetase acetate[mitochondrion] + ATP[mitochondrion] + coenzyme A[mitochondrion] -> acetyl-CoA[mitochondrion] + AMP[mitochondrion] + diphosphate[mitochondrion] +Acetate AcetateExt 0.31 2.297998517 Wasylenko2014 r_1634 acetate exchange acetate[extracellular] -> +OaaCyt OaaMit 0.32 2.372127502 Wasylenko2014 r_4783 oxaloacetate/sulphate antiport, mitochondrial oxaloacetate[cytoplasm] + sulphate[mitochondrion] <=> oxaloacetate[mitochondrion] + sulphate[cytoplasm] +MalMit PyrMit 0.18 1.33432172 Wasylenko2014 r_0718 malic enzyme (NAD) (S)-malate[mitochondrion] + NAD[mitochondrion] -> carbon dioxide[mitochondrion] + NADH[mitochondrion] + pyruvate[mitochondrion] +MalMit OaaMit 0.09 0.66716086 Wasylenko2014 r_0713 malate dehydrogenase (S)-malate[mitochondrion] + NAD[mitochondrion] <=> H+[mitochondrion] + NADH[mitochondrion] + oxaloacetate[mitochondrion] +Fum MalMit 0.1 0.741289844 Wasylenko2014 r_0451 fumarase fumarate[mitochondrion] + H2O[mitochondrion] <=> (S)-malate[mitochondrion] +Cit Akg 0.23 1.704966642 Wasylenko2014 r_0658 isocitrate dehydrogenase (NAD+) isocitrate[mitochondrion] + NAD[mitochondrion] -> 2-oxoglutarate[mitochondrion] + carbon dioxide[mitochondrion] + NADH[mitochondrion] +OaaMit Cit 0.23 1.704966642 Wasylenko2014 r_0300 citrate synthase acetyl-CoA[mitochondrion] + H2O[mitochondrion] + oxaloacetate[mitochondrion] -> citrate[mitochondrion] + coenzyme A[mitochondrion] + H+[mitochondrion] +AcCoaCyt AcCoaMit 0.3 2.223869533 Wasylenko2014 r_0252 carnitine O-acetyltransferase (R)-carnitine[cytoplasm] + acetyl-CoA[cytoplasm] -> coenzyme A[cytoplasm] + O-acetylcarnitine[cytoplasm] +mu out 1 0.1 1.700102006 Nissen01 r_2111 growth biomass[cytoplasm] -> +glucose_v out 1 5.882 100 Nissen01 r_1714 D-glucose exchange D-glucose[extracellular] <=> +CO2_y out 6 0.272 163.2 Nissen01 r_1672 'carbon dioxide exchange' 'carbon dioxide[extracellular] -> ' +ethanol_y out 3 0.497 149.1 Nissen01 r_1761 ethanol exchange ethanol[extracellular] -> +glycerol_y out 2 0.086 17.2 Nissen01 r_1808 glycerol exchange glycerol[extracellular] -> +succinate_y out 1.5 0.003 0.45 Nissen01 r_2056 succinate exchange succinate[extracellular] -> +acetic_y out 3 0.002 0.6 Nissen01 +pyruvate_y out 2 0.001 0.2 Nissen01 +protein out 1 0.45 45 Nissen01 +RNA out 1 0.063 6.3 Nissen01 +NH4_v out 1 0.093 9.3 Nissen01 +mannan out 1 0.131 13.1 Nissen01 +trehalose out 1 0.08 8 Nissen01 +glycogen out 1 0.084 8.4 Nissen01 +other_cs out 1 0.184 18.4 Nissen01 +mu out 1 0.2 1.767721407 Nissen02 r_2111 growth biomass[cytoplasm] -> +glucose_v out 1 11.314 100 Nissen02 r_1714 D-glucose exchange D-glucose[extracellular] <=> +CO2_y out 6 0.273 163.8 Nissen02 r_1672 'carbon dioxide exchange' 'carbon dioxide[extracellular] -> ' +ethanol_y out 3 0.496 148.8 Nissen02 r_1761 ethanol exchange ethanol[extracellular] -> +glycerol_y out 2 0.091 18.2 Nissen02 r_1808 glycerol exchange glycerol[extracellular] -> +succinate_y out 1.5 0.003 0.45 Nissen02 r_2056 succinate exchange succinate[extracellular] -> +acetic_y out 3 0.003 0.9 Nissen02 +pyruvate_y out 2 0.002 0.4 Nissen02 +protein out 1 0.5 50 Nissen02 +RNA out 1 0.082 8.2 Nissen02 +NH4_v out 1 0.11 11 Nissen02 +mannan out 1 0.129 12.9 Nissen02 +trehalose out 1 0.02 2 Nissen02 +glycogen out 1 0.042 4.2 Nissen02 +other_cs out 1 0.154 15.4 Nissen02 +mu out 1 0.3 1.79147259 Nissen03 r_2111 growth biomass[cytoplasm] -> +glucose_v out 1 16.746 100 Nissen03 r_1714 D-glucose exchange D-glucose[extracellular] <=> +CO2_y out 6 0.267 160.2 Nissen03 r_1672 'carbon dioxide exchange' 'carbon dioxide[extracellular] -> ' +ethanol_y out 3 0.494 148.2 Nissen03 r_1761 ethanol exchange ethanol[extracellular] -> +glycerol_y out 2 0.095 19 Nissen03 r_1808 glycerol exchange glycerol[extracellular] -> +succinate_y out 1.5 0.002 0.3 Nissen03 r_2056 succinate exchange succinate[extracellular] -> +acetic_y out 3 0.006 1.8 Nissen03 +pyruvate_y out 2 0.003 0.6 Nissen03 +protein out 1 0.555 55.5 Nissen03 +RNA out 1 0.101 10.1 Nissen03 +NH4_v out 1 0.13 13 Nissen03 +mannan out 1 0.12 12 Nissen03 +trehalose out 1 0 0 Nissen03 +glycogen out 1 0.06 6 Nissen03 +other_cs out 1 0.126 12.6 Nissen03 +mu out 1 0.4 1.803589142 Nissen04 r_2111 growth biomass[cytoplasm] -> +glucose_v out 1 22.178 100 Nissen04 r_1714 D-glucose exchange D-glucose[extracellular] <=> +CO2_y out 6 0.261 156.6 Nissen04 r_1672 'carbon dioxide exchange' 'carbon dioxide[extracellular] -> ' +ethanol_y out 3 0.497 149.1 Nissen04 r_1761 ethanol exchange ethanol[extracellular] -> +glycerol_y out 2 0.109 21.8 Nissen04 r_1808 glycerol exchange glycerol[extracellular] -> +succinate_y out 1.5 0.002 0.3 Nissen04 r_2056 succinate exchange succinate[extracellular] -> +acetic_y out 3 0.01 3 Nissen04 +pyruvate_y out 2 0.004 0.8 Nissen04 +protein out 1 0.6 60 Nissen04 +RNA out 1 0.121 12.1 Nissen04 +NH4_v out 1 0.15 15 Nissen04 +mannan out 1 0.133 13.3 Nissen04 +trehalose out 1 0 0 Nissen04 +glycogen out 1 0 0 Nissen04 +other_cs out 1 0.037 3.7 Nissen04 diff --git a/data/testResults/v910_anaerobic_fluxes.png b/data/testResults/v910_anaerobic_fluxes.png new file mode 100644 index 0000000000000000000000000000000000000000..d319c0ce64e314f3679faefea8bc2fe0f58736ff GIT binary patch literal 142631 zcmeFZWmuGL_dYs^5)U9DjWh^Iw=^iBqzIDIsdRU!2t$b?(xD(FA|28ag3`@^bVy2< z)L!HBzW=@dAAZNNKkQF??>Ua=kr-y~xvq7sb*}R~*ByReU5Vfy>VFUj1i`(#@(&OQ zEE)vj@*K`3_z72k+jIB_*ZHo#8v;Q=g8mP~CSw4eg}`>dr>20tigg87^s*sOhdca; z#a%(qUCYVZ-OJ3?3ZW*attxk$i$UAgib2iH-B#Dh)y|EJ;hv)fkEGrtB|M)A{ro$w 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@@ -7,7 +7,7 @@ r_0005 UDP-D-glucose[c] => (1->3)-beta-D-glucan[ce] + H+[c] + UDP[c] (YPR165W a r_0006 UDP-D-glucose[c] => (1->6)-beta-D-glucan[ce] + H+[c] + UDP[c] YGR143W or YPR159W 0.00 1000.00 0.00 r_0007 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide[c] => 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide[c] YIL020C 0.00 1000.00 0.00 r_0012 1-pyrroline-5-carboxylate[m] + 2 H2O[m] + NAD[m] => H+[m] + L-glutamate[m] + NADH[m] YHR037W 0.00 1000.00 0.00 -r_0013 5-(methylsulfanyl)-2,3-dioxopentyl phosphate[c] + 3 H2O[c] => 4-methylthio-2-oxobutanoate[c] + formate[c] + 6 H+[c] + phosphate[c] YEL038W and YMR009W 0.00 1000.00 0.00 +r_0013 5-(methylsulfanyl)-2,3-dioxopentyl phosphate[c] + H2O[c] + oxygen[c] => 4-methylthio-2-oxobutanoate[c] + formate[c] + 2 H+[c] + phosphate[c] YEL038W and YMR009W 0.00 1000.00 0.00 r_0014 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone[c] + H+[c] + H2O[c] => 5-amino-6-(5-phosphoribitylamino)uracil[c] + ammonium[c] YOL066C 0.00 1000.00 0.00 r_0015 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine[c] + H+[c] + NADPH[c] => 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone[c] + NADP(+)[c] YBR153W 0.00 1000.00 0.00 r_0016 2-oxobutanoate[m] + H+[m] + pyruvate[m] => (S)-2-acetyl-2-hydroxybutanoate[m] + carbon dioxide[m] (YCL009C and YMR108W) or YMR108W 0.00 1000.00 0.00 @@ -201,7 +201,7 @@ r_0222 ADP[c] + ATP[c] + H+[c] => P(1),P(4)-bis(5'-adenosyl) tetraphosphate[c] + r_0223 ADP[c] + GTP[c] + H+[c] => P1-(5'-adenosyl),P4-(5'-guanosyl) tetraphosphate[c] + phosphate[c] YCL050C 0.00 1000.00 0.00 r_0224 GDP[c] + GTP[c] + H+[c] => P(1),P(4)-bis(5'-guanosyl) tetraphosphate[c] + phosphate[c] YCL050C 0.00 1000.00 0.00 r_0225 ATP[c] + PRPP[c] => 5-phosphoribosyl-ATP[c] + diphosphate[c] YER055C 0.00 1000.00 0.00 -r_0226 ADP[m] + 3 H+[c] + phosphate[m] => ATP[m] + 2 H+[m] + H2O[m] Q0080 and Q0085 and Q0130 and YBL099W and YBR039W and YDL004W and YDR298C and YDR377W and YJR121W and YKL016C and YLR295C and YML081C-A and YPL078C and YPL271W and YDR322C-A and YPR020W and YOL077W-A 0.00 1000.00 0.00 +r_0226 ADP[m] + 3 H+[c] + phosphate[m] <=> ATP[m] + 2 H+[m] + H2O[m] Q0080 and Q0085 and Q0130 and YBL099W and YBR039W and YDL004W and YDR298C and YDR377W and YJR121W and YKL016C and YLR295C and YML081C-A and YPL078C and YPL271W and YDR322C-A and YPR020W and YOL077W-A -1000.00 1000.00 0.00 r_0227 ATP[c] + H2O[c] => ADP[c] + H+[e] + phosphate[c] (YCR024C-A and YEL017C-A and YGL008C) or (YCR024C-A and YEL017C-A and YPL036W) or YER005W 0.00 1000.00 0.00 r_0228 GDP-alpha-D-mannose[c] + N,N'-diacetylchitobiosyldiphosphodolichol[c] => beta-D-mannosyldiacetylchitobiosyldiphosphodolichol[c] + GDP[c] + H+[c] YBR110W 0.00 1000.00 0.00 r_0229 dethiobiotin[c] + polysulphur[c] <=> biotin[c] + 2 H+[c] YGR286C -1000.00 1000.00 0.00 @@ -215,13 +215,13 @@ r_0237 H+[c] + NADPH[c] + zymosterol intermediate 2[c] => NADP(+)[c] + zymostero r_0238 4alpha-methylzymosterol[c] + H+[c] + NADPH[c] + oxygen[c] => H2O[c] + NADP(+)[c] + zymosterol intermediate 1a[c] YGR060W 0.00 1000.00 0.00 r_0239 H+[c] + NADPH[c] + oxygen[c] + zymosterol intermediate 1a[c] => 2 H2O[c] + NADP(+)[c] + zymosterol intermediate 1b[c] YGR060W 0.00 1000.00 0.00 r_0240 NADPH[c] + oxygen[c] + zymosterol intermediate 1b[c] => H2O[c] + NADP(+)[c] + zymosterol intermediate 1c[c] YGR060W 0.00 1000.00 0.00 -r_0241 14-demethyllanosterol[c] + 5 H+[c] + 3 oxygen[c] + 6 Ferrocytochrome b5[erm] => 4beta-methylzymosterol-4alpha-carboxylic acid[c] + 4 H2O[c] + 6 Ferricytochrome b5[erm] YGR060W 0.00 1000.00 0.00 +r_0241 14-demethyllanosterol[c] + 5 H+[c] + 3 oxygen[c] + 6 ferrocytochrome b5[erm] => 4beta-methylzymosterol-4alpha-carboxylic acid[c] + 4 H2O[c] + 6 ferricytochrome b5[erm] YGR060W 0.00 1000.00 0.00 r_0242 episterol[c] + H+[c] + NADPH[c] + oxygen[c] => ergosta-5,7,24(28)-trien-3beta-ol[c] + 2 H2O[c] + NADP(+)[c] YLR056W 0.00 1000.00 0.00 r_0243 fecosterol[c] => episterol[c] YMR202W 0.00 1000.00 0.00 r_0244 ergosta-5,7,22,24(28)-tetraen-3beta-ol[er] + H+[er] + NADPH[er] => ergosterol[er] + NADP(+)[er] YGL012W 0.00 1000.00 0.00 r_0249 4-hydroxybenzoate[c] + nonaprenyl diphosphate[c] => diphosphate[c] + nonaprenyl 4-hydroxybenzoate[c] YDL090C and YKL019W 0.00 1000.00 0.00 r_0250 2 ATP[c] + bicarbonate[c] + H2O[c] + L-glutamine[c] => 2 ADP[c] + carbamoyl phosphate[c] + 2 H+[c] + L-glutamate[c] + phosphate[c] YJL130C or (YJR109C and YOR303W) 0.00 1000.00 0.00 -r_0252 (R)-carnitine[c] + acetyl-CoA[c] => coenzyme A[c] + O-acetylcarnitine[c] YAR035W or YER024W 0.00 1000.00 0.00 +r_0252 (R)-carnitine[c] + acetyl-CoA[c] => coenzyme A[c] + O-acetylcarnitine[c] YAR035W or YER024W 0.00 0.00 0.00 r_0253 (R)-carnitine[p] + acetyl-CoA[p] => coenzyme A[p] + O-acetylcarnitine[p] YML042W 0.00 1000.00 0.00 r_0254 coenzyme A[m] + O-acetylcarnitine[m] => (R)-carnitine[m] + acetyl-CoA[m] YML042W 0.00 1000.00 0.00 r_0255 2 hydrogen peroxide[c] => 2 H2O[c] + oxygen[c] YGR088W 0.00 1000.00 0.00 @@ -340,7 +340,7 @@ r_0441 FMN[c] + 2 H+[c] + NADH[c] => FMNH2[c] + NAD[c] YLR011W 0.00 1000.00 r_0442 FMN[c] + 2 H+[c] + NADPH[c] => FMNH2[c] + NADP(+)[c] YLR011W 0.00 1000.00 0.00 r_0443 formaldehyde[c] + glutathione[c] + NAD[c] => H+[c] + NADH[c] + S-formylglutathione[c] YDL168W 0.00 1000.00 0.00 r_0445 formate[c] + NAD[c] => carbon dioxide[c] + NADH[c] YOR388C 0.00 1000.00 0.00 -r_0446 ATP[c] + formate[c] + THF[c] => 10-formyl-THF[c] + ADP[c] + phosphate[c] YGR204W 0.00 1000.00 0.00 +r_0446 ATP[c] + formate[c] + THF[c] <=> 10-formyl-THF[c] + ADP[c] + phosphate[c] YGR204W -1000.00 1000.00 0.00 r_0447 ATP[m] + formate[m] + THF[m] <=> 10-formyl-THF[m] + ADP[m] + phosphate[m] YBR084W -1000.00 1000.00 0.00 r_0448 beta-D-fructose 2,6-bisphosphate[c] + H2O[c] => D-fructose 6-phosphate[c] + phosphate[c] YLR345W or YJL155C 0.00 1000.00 0.00 r_0449 D-fructose 1,6-bisphosphate[c] + H2O[c] => D-fructose 6-phosphate[c] + phosphate[c] YLR377C 0.00 1000.00 0.00 @@ -365,7 +365,7 @@ r_0468 ATP[c] + L-glutamate[c] => ADP[c] + L-gamma-glutamyl phosphate[c] YDR300 r_0469 H+[c] + L-glutamate[c] => carbon dioxide[c] + gamma-aminobutyrate[c] YMR250W 0.00 1000.00 0.00 r_0470 H2O[c] + L-glutamate[c] + NAD[c] => 2-oxoglutarate[c] + ammonium[c] + H+[c] + NADH[c] YDL215C 0.00 1000.00 0.00 r_0471 2-oxoglutarate[c] + ammonium[c] + H+[c] + NADPH[c] => H2O[c] + L-glutamate[c] + NADP(+)[c] YAL062W or YOR375C 0.00 1000.00 0.00 -r_0472 2-oxoglutarate[c] + H+[c] + L-glutamine[c] + NADH[c] => 2 L-glutamate[c] + NAD[c] YDL171C 0.00 1000.00 0.00 +r_0472 2-oxoglutarate[c] + H+[c] + L-glutamine[c] + NADH[c] => 2 L-glutamate[c] + NAD[c] YDL171C 0.00 0.00 0.00 r_0473 H+[c] + L-gamma-glutamyl phosphate[c] + NADPH[c] => L-glutamic 5-semialdehyde[c] + NADP(+)[c] + phosphate[c] YOR323C 0.00 1000.00 0.00 r_0475 H2O[c] + L-glutamine[c] => ammonium[c] + L-glutamate[c] YFL060C or YNL334C 0.00 1000.00 0.00 r_0476 ammonium[c] + ATP[c] + L-glutamate[c] => ADP[c] + H+[c] + L-glutamine[c] + phosphate[c] YPR035W 0.00 1000.00 0.00 @@ -379,7 +379,7 @@ r_0483 2 glutathione[c] + hydrogen peroxide[c] => glutathione disulfide[c] + 2 H r_0484 2 glutathione[m] + hydrogen peroxide[m] => glutathione disulfide[m] + 2 H2O[m] YPL059W 0.00 1000.00 0.00 r_0485 ATP[c] + L-gamma-glutamyl-L-cysteine[c] + L-glycine[c] => ADP[c] + glutathione[c] + H+[c] + phosphate[c] YOL049W 0.00 1000.00 0.00 r_0486 glyceraldehyde 3-phosphate[c] + NAD[c] + phosphate[c] <=> 1,3-bisphospho-D-glycerate[c] + H+[c] + NADH[c] YGR192C or YJL052W or YJR009C -1000.00 1000.00 0.00 -r_0487 glycerol[c] + NADP(+)[c] => glycerone[c] + H+[c] + NADPH[c] YOR120W 0.00 1000.00 0.00 +r_0487 glycerone[c] + H+[c] + NADPH[c] => glycerol[c] + NADP(+)[c] YOR120W 0.00 1000.00 0.00 r_0488 ATP[c] + glycerol[c] => ADP[c] + glycerol 3-phosphate[c] + H+[c] YHL032C 0.00 1000.00 0.00 r_0489 glycerol 3-phosphate[c] + H2O[c] => glycerol[c] + phosphate[c] YER062C or YIL053W 0.00 1000.00 0.00 r_0490 FAD[m] + glycerol 3-phosphate[m] + H+[m] => dihydroxyacetone phosphate[m] + FADH2[m] YIL155C 0.00 1000.00 0.00 @@ -388,15 +388,15 @@ r_0492 dihydroxyacetone phosphate[m] + H+[m] + NADH[m] => glycerol 3-phosphate[m r_0497 H2O[c] + sn-glycero-3-phosphocholine[c] => choline[c] + glycerol 3-phosphate[c] + H+[c] YPL110C 0.00 1000.00 0.00 r_0499 10-formyl-THF[c] + 5-phospho-ribosyl-glycineamide[c] => 5'-phosphoribosyl-N-formylglycineamide[c] + H+[c] + THF[c] YDR408C 0.00 1000.00 0.00 r_0500 coenzyme A[c] + L-2-amino-3-oxobutanoate[c] => acetyl-CoA[c] + L-glycine[c] 0.00 1000.00 0.00 -r_0501 L-glycine[m] + NAD[m] + THF[m] => 5,10-methylenetetrahydrofolate[m] + ammonium[m] + carbon dioxide[m] + NADH[m] YAL044C and YDR019C and YFL018C and YMR189W 0.00 1000.00 0.00 +r_0501 L-glycine[m] + NAD[m] + THF[m] => 5,10-methylenetetrahydrofolate[m] + ammonium[m] + carbon dioxide[m] + NADH[m] YAL044C and YDR019C and YFL018C and YMR189W 0.00 0.00 0.00 r_0502 L-serine[c] + THF[c] <=> 5,10-methylenetetrahydrofolate[c] + H2O[c] + L-glycine[c] YLR058C -1000.00 1000.00 0.00 r_0503 L-serine[m] + THF[m] <=> 5,10-methylenetetrahydrofolate[m] + H2O[m] + L-glycine[m] YBR263W -1000.00 1000.00 0.00 r_0504 H+[m] + L-glycine[m] + lipoamide[m] => carbon dioxide[m] + S(8)-aminomethyldihydrolipoamide[m] YAL044C and YDR019C and YFL018C and YMR189W 0.00 1000.00 0.00 r_0505 dihydrolipoamide[m] + NAD[m] => H+[m] + lipoamide[m] + NADH[m] (YAL044C and YDR019C and YFL018C and YMR189W) or (YDR148C and YFL018C and YIL125W) 0.00 1000.00 0.00 r_0506 L-glycine[m] + lipoylprotein[m] => carbon dioxide[m] + S(8)-aminomethyldihydrolipoylprotein[m] YAL044C and YDR019C and YFL018C and YMR189W 0.00 1000.00 0.00 -r_0507 H+[m] + S(8)-aminomethyldihydrolipoylprotein[m] + THF[m] => 5,10-methylenetetrahydrofolate[m] + ammonium[m] + dihydrolipoylprotein[m] YAL044C and YDR019C and YFL018C and YMR189W 0.00 1000.00 0.00 +r_0507 H+[m] + S(8)-aminomethyldihydrolipoylprotein[m] + THF[m] => 5,10-methylenetetrahydrofolate[m] + ammonium[m] + dihydrolipoylprotein[m] YAL044C and YDR019C and YFL018C and YMR189W 0.00 0.00 0.00 r_0508 dihydrolipoylprotein[m] + NAD[m] => H+[m] + lipoylprotein[m] + NADH[m] YAL044C and YDR019C and YFL018C and YMR189W 0.00 1000.00 0.00 -r_0509 S(8)-aminomethyldihydrolipoamide[m] + THF[m] => 5,10-methylenetetrahydrofolate[m] + ammonium[m] + dihydrolipoamide[m] YAL044C and YDR019C and YFL018C and YMR189W 0.00 1000.00 0.00 +r_0509 S(8)-aminomethyldihydrolipoamide[m] + THF[m] => 5,10-methylenetetrahydrofolate[m] + ammonium[m] + dihydrolipoamide[m] YAL044C and YDR019C and YFL018C and YMR189W 0.00 0.00 0.00 r_0510 UDP-D-glucose[c] => glycogen[c] + H+[c] + UDP[c] (YFR015C and YJL137C) or (YFR015C and YKR058W) or (YJL137C and YLR258W) or (YKR058W and YLR258W) 0.00 1000.00 0.00 r_0511 glycogen[c] + phosphate[c] => D-glucose 1-phosphate[c] YPR160W 0.00 1000.00 0.00 r_0512 ATP[c] + L-glycine[c] + tRNA(Gly)[c] => AMP[c] + diphosphate[c] + Gly-tRNA(Gly)[c] YBR121C or YPR081C 0.00 1000.00 0.00 @@ -575,7 +575,7 @@ r_0716 acetyl-CoA[c] + glyoxylate[c] + H2O[c] => (S)-malate[c] + coenzyme A[c] + r_0717 acetyl-CoA[p] + glyoxylate[p] + H2O[p] => (S)-malate[p] + coenzyme A[p] + H+[p] YNL117W 0.00 1000.00 0.00 r_0718 (S)-malate[m] + NAD[m] => carbon dioxide[m] + NADH[m] + pyruvate[m] YKL029C 0.00 1000.00 0.00 r_0719 (S)-malate[m] + NADP(+)[m] => carbon dioxide[m] + NADPH[m] + pyruvate[m] YKL029C 0.00 1000.00 0.00 -r_0721 malonyl-CoA[m] + ACP1[m] <=> carboxyacetyl-ACP[m] + coenzyme A[m] YKL192C and YOR221C -1000.00 1000.00 0.00 +r_0721 H+[m] + malonyl-CoA[m] + ACP1[m] <=> carboxyacetyl-ACP[m] + coenzyme A[m] YKL192C and YOR221C -1000.00 1000.00 0.00 r_0722 D-mannose 1-phosphate[c] + GTP[c] + H+[c] => diphosphate[c] + GDP-alpha-D-mannose[c] YDL055C 0.00 1000.00 0.00 r_0723 D-mannose 6-phosphate[c] <=> D-fructose 6-phosphate[c] YER003C -1000.00 1000.00 0.00 r_0724 5,10-methenyl-THF[m] + H2O[m] <=> 10-formyl-THF[m] + H+[m] YBR084W -1000.00 1000.00 0.00 @@ -586,8 +586,8 @@ r_0728 10-formyl-THF[m] + Met-tRNA(Met)[m] => fMet-tRNA(fMet)[m] + H+[m] + THF[m r_0729 ATP[c] + L-methionine[c] + tRNA(Met)[c] => AMP[c] + diphosphate[c] + Met-tRNA(Met)[c] YGR264C 0.00 1000.00 0.00 r_0730 ATP[m] + L-methionine[m] + tRNA(Met)[m] => AMP[m] + diphosphate[m] + Met-tRNA(Met)[m] YGR171C 0.00 1000.00 0.00 r_0731 5,10-methylenetetrahydrofolate[c] + NAD[c] => 5,10-methenyl-THF[c] + NADH[c] YKR080W 0.00 1000.00 0.00 -r_0732 5,10-methylenetetrahydrofolate[c] + NADP(+)[c] <=> 5,10-methenyl-THF[c] + NADPH[c] YGR204W -1000.00 1000.00 0.00 -r_0733 5,10-methylenetetrahydrofolate[m] + NADP(+)[m] <=> 5,10-methenyl-THF[m] + NADPH[m] YBR084W -1000.00 1000.00 0.00 +r_0732 5,10-methenyl-THF[c] + NADPH[c] <=> 5,10-methylenetetrahydrofolate[c] + NADP(+)[c] YGR204W 0.00 1000.00 0.00 +r_0733 5,10-methenyl-THF[m] + NADPH[m] <=> 5,10-methylenetetrahydrofolate[m] + NADP(+)[m] YBR084W 0.00 1000.00 0.00 r_0734 (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid[m] => pyruvate[m] + succinate[m] YPR006C 0.00 1000.00 0.00 r_0735 (R)-mevalonate[c] + ATP[c] => (R)-5-phosphomevalonic acid[c] + ADP[c] + H+[c] YMR208W 0.00 1000.00 0.00 r_0736 (R)-mevalonate[c] + CTP[c] => (R)-5-phosphomevalonic acid[c] + CDP[c] + H+[c] YMR208W 0.00 1000.00 0.00 @@ -621,8 +621,8 @@ r_0770 H+[c] + NADH[c] + ubiquinone-6[m] => NAD[c] + ubiquinol-6[m] YDL085W or r_0771 ATP[c] + NADH[c] => ADP[c] + H+[c] + NADPH[c] YEL041W or YJR049C 0.00 1000.00 0.00 r_0772 ATP[m] + NADH[m] => ADP[m] + H+[m] + NADPH[m] YEL041W or YJR049C or YPL188W 0.00 1000.00 0.00 r_0773 H+[m] + NADH[m] + ubiquinone-6[m] => NAD[m] + ubiquinol-6[m] YML120C 0.00 1000.00 0.00 -r_0774 ATP[c] + H+[c] + nicotinate[c] + PRPP[c] => ADP[c] + diphosphate[c] + nicotinic acid D-ribonucleotide[c] + phosphate[c] YOR209C 0.00 1000.00 0.00 -r_0775 ATP[m] + H+[m] + nicotinate[m] + PRPP[m] => ADP[m] + diphosphate[m] + nicotinic acid D-ribonucleotide[m] + phosphate[m] YOR209C 0.00 1000.00 0.00 +r_0774 ATP[c] + H2O[c] + nicotinate[c] + PRPP[c] => ADP[c] + diphosphate[c] + nicotinic acid D-ribonucleotide[c] + phosphate[c] YOR209C 0.00 1000.00 0.00 +r_0775 ATP[m] + H2O[m] + nicotinate[m] + PRPP[m] => ADP[m] + diphosphate[m] + nicotinic acid D-ribonucleotide[m] + phosphate[m] YOR209C 0.00 1000.00 0.00 r_0781 H2O[c] + nicotinamide[c] => ammonium[c] + nicotinate[c] YGL037C 0.00 1000.00 0.00 r_0782 nicotinamide[c] + S-adenosyl-L-methionine[c] => 1-methylnicotinamide[c] + S-adenosyl-L-homocysteine[c] YLR285W 0.00 1000.00 0.00 r_0783 ATP[c] + H+[c] + NMN[c] => diphosphate[c] + NAD[c] YCL047C or YLR328W 0.00 1000.00 0.00 @@ -648,7 +648,7 @@ r_0803 ATP[c] + dUDP[c] <=> ADP[c] + dUTP[c] YKL067W -1000.00 1000.00 0.00 r_0804 GTP[c] + H2O[c] => GDP[c] + H+[c] + phosphate[c] YAL035W or YLL001W or YER005W 0.00 1000.00 0.00 r_0805 H2O[c] + UTP[c] => H+[c] + phosphate[c] + UDP[c] YER005W 0.00 1000.00 0.00 r_0806 CTP[c] + H2O[c] => CDP[c] + H+[c] + phosphate[c] YER005W 0.00 1000.00 0.00 -r_0807 H2O[c] + ITP[c] => H+[c] + IDP[c] + phosphate[c] YER005W 0.00 1000.00 0.00 +r_0807 H2O[c] + ITP[c] => H+[c] + IDP[c] + phosphate[c] YJR069C 0.00 1000.00 0.00 r_0810 GDP[g] + H2O[g] => GMP[g] + H+[g] + phosphate[g] YEL042W 0.00 1000.00 0.00 r_0811 ATP[c] + UDP[c] => ADP[c] + UTP[c] YKL067W 0.00 1000.00 0.00 r_0812 methanethiol[c] + O-acetyl-L-homoserine[c] => acetate[c] + H+[c] + L-methionine[c] YLR303W 0.00 1000.00 0.00 @@ -681,7 +681,6 @@ r_0883 3'-phospho-5'-adenylyl sulfate[c] + TRX1[c] => adenosine 3',5'-bismonopho r_0884 ATP[c] + oxaloacetate[c] => ADP[c] + carbon dioxide[c] + phosphoenolpyruvate[c] YKR097W 0.00 1000.00 0.00 r_0885 CTP[c] + H+[c] + O-phosphoethanolamine[c] => CDP-ethanolamine[c] + diphosphate[c] YGR007W 0.00 1000.00 0.00 r_0886 ATP[c] + D-fructose 6-phosphate[c] => ADP[c] + D-fructose 1,6-bisphosphate[c] + H+[c] YGR240C and YMR205C 0.00 1000.00 0.00 -r_0887 ATP[c] + sedoheptulose 7-phosphate[c] => ADP[c] + H+[c] + sedoheptulose 1,7-bisphosphate[c] YGR240C and YMR205C 0.00 1000.00 0.00 r_0888 D-glucose 6-phosphate[c] <=> D-glucose 1-phosphate[c] YMR105C or YKL127W -1000.00 1000.00 0.00 r_0889 6-phospho-D-gluconate[c] + NADP(+)[c] => carbon dioxide[c] + D-ribulose 5-phosphate[c] + NADPH[c] YGR256W or YHR183W 0.00 1000.00 0.00 r_0890 alpha-D-glucosamine 1-phosphate[c] <=> alpha-D-glucosamine 6-phosphate[c] YEL058W -1000.00 1000.00 0.00 @@ -714,7 +713,7 @@ r_0935 2 5-aminolevulinate[c] => H+[c] + 2 H2O[c] + porphobilinogen[c] YGL040C r_0936 H2O[c] + N(1)-acetylspermine[c] + oxygen[c] => 3-aminopropanal[c] + hydrogen peroxide[c] + N(1)-acetylspermidine[c] YMR020W 0.00 1000.00 0.00 r_0937 H2O[c] + oxygen[c] + spermine[c] => 3-aminopropanal[c] + hydrogen peroxide[c] + spermidine[c] YMR020W 0.00 1000.00 0.00 r_0938 H+[c] + prephenate[c] => carbon dioxide[c] + H2O[c] + keto-phenylpyruvate[c] YNL316C 0.00 1000.00 0.00 -r_0939 NADP(+)[c] + prephenate[c] => 3-(4-hydroxyphenyl)pyruvate[c] + carbon dioxide[c] + NADPH[c] YBR166C 0.00 1000.00 0.00 +r_0939 NAD[c] + prephenate[c] => 3-(4-hydroxyphenyl)pyruvate[c] + carbon dioxide[c] + NADH[c] YBR166C 0.00 1000.00 0.00 r_0940 FAD[m] + L-proline[m] => 1-pyrroline-5-carboxylate[m] + FADH2[m] YLR142W 0.00 1000.00 0.00 r_0941 ATP[c] + L-proline[c] + tRNA(Pro)[c] => AMP[c] + diphosphate[c] + Pro-tRNA(Pro)[c] YHR020W 0.00 1000.00 0.00 r_0942 3 oxygen[m] + 2 protoporphyrinogen[m] => 6 H2O[m] + 2 protoporphyrin[m] YER014W 0.00 1000.00 0.00 @@ -853,7 +852,7 @@ r_1100 3-hexaprenyl-4,5-dihydroxybenzoic acid[c] <=> 3-hexaprenyl-4,5-dihydroxyb r_1101 gamma-aminobutyrate[e] + H+[e] => gamma-aminobutyrate[c] + H+[c] YDL210W or YOR348C 0.00 1000.00 0.00 r_1102 5-aminolevulinate[e] + H+[e] => 5-aminolevulinate[c] + H+[c] YDL210W 0.00 1000.00 0.00 r_1103 5-formyltetrahydrofolic acid[e] <=> 5-formyltetrahydrofolic acid[c] -1000.00 1000.00 0.00 -r_1104 8-amino-7-oxononanoate[e] + H+[e] <=> 8-amino-7-oxononanoate[c] + H+[c] YNR056C -1000.00 1000.00 0.00 +r_1104 8-amino-7-oxononanoate[e] + H+[e] <=> 8-amino-7-oxononanoate[c] + H+[c] YNR056C 0.00 1000.00 0.00 r_1106 acetate[c] <=> acetate[e] YCR010C -1000.00 1000.00 0.00 r_1107 ethyl acetate[c] => ethyl acetate[e] 0.00 1000.00 0.00 r_1108 adenine[e] + H+[e] => adenine[c] + H+[c] YER056C or YER060W or YER060W-A 0.00 1000.00 0.00 @@ -883,7 +882,7 @@ r_1132 cytidine[e] + H+[e] => cytidine[c] + H+[c] YAL022C 0.00 1000.00 0.00 r_1133 cytosine[e] + H+[e] => cytosine[c] + H+[c] YER056C or YER060W or YER060W-A or YGL186C 0.00 1000.00 0.00 r_1134 D-fructose[e] => D-fructose[c] YDL245C or YDR342C or YDR343C or YDR345C or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YMR011W or YNR072W or YOL156W 0.00 1000.00 0.00 r_1135 D-galactose[e] + H+[e] => D-galactose[c] + H+[c] YFL011W or YJL219W or YLR081W or YNL318C or YOL156W 0.00 1000.00 0.00 -r_1136 (R)-lactate[e] + H+[e] <=> (R)-lactate[c] + H+[c] YKL217W -1000.00 1000.00 0.00 +r_1136 (R)-lactate[e] + H+[e] <=> (R)-lactate[c] + H+[c] YKL217W 0.00 1000.00 0.00 r_1137 (R)-lactate[c] + H+[c] => (R)-lactate[m] + H+[m] 0.00 1000.00 0.00 r_1138 (R)-lactate[c] + pyruvate[m] <=> (R)-lactate[m] + pyruvate[c] -1000.00 1000.00 0.00 r_1139 D-mannose[e] + H+[e] => D-mannose[c] + H+[c] YDL245C or YDR342C or YHR094C or YDR343C or YDR345C or YEL069C or YFL011W or YHR096C or YJL214W or YJL219W or YJR158W or YNR072W or YOL156W 0.00 1000.00 0.00 @@ -906,55 +905,55 @@ r_1172 glycerol[c] => glycerol[e] YFL054C or YLL043W 0.00 1000.00 0.00 r_1173 H+[e] + L-glycine[e] <=> H+[c] + L-glycine[c] YCL025C or YKR039W or YOL020W or YOR348C or YPL265W -1000.00 1000.00 0.00 r_1174 glycogen[c] => glycogen[v] 0.00 1000.00 0.00 r_1175 GDP[m] + GTP[c] + H+[c] => GDP[c] + GTP[m] + H+[m] YDL198C 0.00 1000.00 0.00 -r_1176 guanine[e] + H+[e] <=> guanine[c] + H+[c] YER056C or YER060W or YER060W-A -1000.00 1000.00 0.00 +r_1176 guanine[e] + H+[e] <=> guanine[c] + H+[c] YER056C or YER060W or YER060W-A 0.00 1000.00 0.00 r_1177 H+[e] + myo-inositol[e] => H+[c] + myo-inositol[c] YDR497C or YOL103W 0.00 1000.00 0.00 r_1178 iron(2+)[e] => iron(2+)[c] YMR319C or YMR058W 0.00 1000.00 0.00 r_1179 iron(2+)[c] => iron(2+)[m] YJL133W or YKR052C 0.00 1000.00 0.00 r_1180 isoamyl acetate[c] => isoamyl acetate[e] 0.00 1000.00 0.00 r_1181 isobutyl acetate[c] => isobutyl acetate[e] 0.00 1000.00 0.00 r_1182 isopentenyl diphosphate[c] <=> isopentenyl diphosphate[m] -1000.00 1000.00 0.00 -r_1183 H+[e] + L-alanine[e] <=> H+[c] + L-alanine[c] YCL025C or YKR039W or YOR348C or YPL265W -1000.00 1000.00 0.00 -r_1184 H+[e] + L-arginine[e] <=> H+[c] + L-arginine[c] YEL063C or YKR039W or YNL270C -1000.00 1000.00 0.00 +r_1183 H+[e] + L-alanine[e] <=> H+[c] + L-alanine[c] YCL025C or YKR039W or YOR348C or YPL265W 0.00 1000.00 0.00 +r_1184 H+[e] + L-arginine[e] <=> H+[c] + L-arginine[c] YEL063C or YKR039W or YNL270C 0.00 1000.00 0.00 r_1185 H+[v] + L-arginine[c] => H+[c] + L-arginine[v] YOL092W or YBR293W 0.00 1000.00 0.00 -r_1186 H+[e] + L-asparagine[e] <=> H+[c] + L-asparagine[c] YCL025C or YDR508C or YKR039W or YPL265W -1000.00 1000.00 0.00 +r_1186 H+[e] + L-asparagine[e] <=> H+[c] + L-asparagine[c] YCL025C or YDR508C or YKR039W or YPL265W 0.00 1000.00 0.00 r_1187 H+[v] + L-asparagine[c] => H+[c] + L-asparagine[v] YJR001W 0.00 1000.00 0.00 r_1188 H+[v] + L-asparagine[v] => H+[c] + L-asparagine[c] YKL146W or YNL101W 0.00 1000.00 0.00 r_1189 H+[v] + L-aspartate[v] => H+[c] + L-aspartate[c] YER119C 0.00 1000.00 0.00 -r_1190 H+[e] + L-aspartate[e] <=> H+[c] + L-aspartate[c] YFL055W or YKR039W or YPL265W -1000.00 1000.00 0.00 +r_1190 H+[e] + L-aspartate[e] <=> H+[c] + L-aspartate[c] YFL055W or YKR039W or YPL265W 0.00 1000.00 0.00 r_1191 (R)-carnitine[e] <=> (R)-carnitine[c] YBR132C -1000.00 1000.00 0.00 -r_1192 H+[e] + L-cysteine[e] <=> H+[c] + L-cysteine[c] YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W or YOL020W -1000.00 1000.00 0.00 +r_1192 H+[e] + L-cysteine[e] <=> H+[c] + L-cysteine[c] YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W or YOL020W 0.00 1000.00 0.00 r_1193 H+[v] + L-cystine[v] => H+[c] + L-cystine[c] YCR075C 0.00 1000.00 0.00 r_1194 L-glutamate[c] => L-glutamate[m] YPR021C 0.00 1000.00 0.00 r_1195 H+[v] + L-glutamate[v] => H+[c] + L-glutamate[c] YER119C 0.00 1000.00 0.00 -r_1196 H+[e] + L-glutamate[e] <=> H+[c] + L-glutamate[c] YCL025C or YFL055W or YKR039W or YPL265W -1000.00 1000.00 0.00 +r_1196 H+[e] + L-glutamate[e] <=> H+[c] + L-glutamate[c] YCL025C or YFL055W or YKR039W or YPL265W 0.00 1000.00 0.00 r_1197 H+[v] + L-glutamine[c] => H+[c] + L-glutamine[v] YJR001W 0.00 1000.00 0.00 r_1198 H+[v] + L-glutamine[v] => H+[c] + L-glutamine[c] YKL146W or YNL101W 0.00 1000.00 0.00 -r_1199 H+[e] + L-glutamine[e] <=> H+[c] + L-glutamine[c] YCL025C or YDR508C or YKR039W or YPL265W -1000.00 1000.00 0.00 +r_1199 H+[e] + L-glutamine[e] <=> H+[c] + L-glutamine[c] YCL025C or YDR508C or YKR039W or YPL265W 0.00 1000.00 0.00 r_1200 H+[v] + L-histidine[c] => H+[c] + L-histidine[v] YOL092W or YBR293W or YCL069W or YMR088C 0.00 1000.00 0.00 -r_1201 H+[e] + L-histidine[e] <=> H+[c] + L-histidine[c] YBR069C or YGR191W or YKR039W -1000.00 1000.00 0.00 +r_1201 H+[e] + L-histidine[e] <=> H+[c] + L-histidine[c] YBR069C or YGR191W or YKR039W 0.00 1000.00 0.00 r_1202 L-isoleucine[v] <=> L-isoleucine[c] YCL038C -1000.00 1000.00 0.00 r_1203 H+[v] + L-isoleucine[c] => H+[c] + L-isoleucine[v] YJR001W 0.00 1000.00 0.00 r_1204 H+[v] + L-isoleucine[v] => H+[c] + L-isoleucine[c] YKL146W or YNL101W 0.00 1000.00 0.00 -r_1205 H+[e] + L-isoleucine[e] <=> H+[c] + L-isoleucine[c] YBR068C or YBR069C or YCL025C or YDR046C or YKR039W -1000.00 1000.00 0.00 +r_1205 H+[e] + L-isoleucine[e] <=> H+[c] + L-isoleucine[c] YBR068C or YBR069C or YCL025C or YDR046C or YKR039W 0.00 1000.00 0.00 r_1206 (S)-lactate[c] <=> (S)-lactate[m] YKL217W -1000.00 1000.00 0.00 r_1207 (S)-lactate[e] + H+[e] => (S)-lactate[c] + H+[c] YKL217W 0.00 1000.00 0.00 r_1208 L-leucine[v] <=> L-leucine[c] YCL038C -1000.00 1000.00 0.00 r_1209 H+[v] + L-leucine[c] => H+[c] + L-leucine[v] YJR001W 0.00 1000.00 0.00 r_1210 H+[v] + L-leucine[v] => H+[c] + L-leucine[c] YKL146W or YNL101W 0.00 1000.00 0.00 -r_1211 H+[e] + L-leucine[e] <=> H+[c] + L-leucine[c] YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W -1000.00 1000.00 0.00 +r_1211 H+[e] + L-leucine[e] <=> H+[c] + L-leucine[c] YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W 0.00 1000.00 0.00 r_1212 H+[v] + L-lysine[c] => H+[c] + L-lysine[v] YOL092W or YBR293W or YCL069W or YMR088C 0.00 1000.00 0.00 -r_1213 H+[e] + L-lysine[e] <=> H+[c] + L-lysine[c] YKR039W or YNL268W -1000.00 1000.00 0.00 -r_1214 H+[e] + L-methionine[e] <=> H+[c] + L-methionine[c] YBR068C or YCL025C or YDR046C or YDR508C or YGR055W or YHL036W or YKR039W -1000.00 1000.00 0.00 -r_1215 H+[e] + L-phenylalanine[e] <=> H+[c] + L-phenylalanine[c] YBR068C or YCL025C or YDR046C or YKR039W or YOL020W -1000.00 1000.00 0.00 -r_1216 H+[e] + L-proline[e] <=> H+[c] + L-proline[c] YKR039W or YOR348C -1000.00 1000.00 0.00 -r_1217 H+[e] + L-serine[e] <=> H+[c] + L-serine[c] YCL025C or YDR508C or YFL055W or YKR039W or YPL265W or YDR105C -1000.00 1000.00 0.00 -r_1218 H+[e] + L-threonine[e] <=> H+[c] + L-threonine[c] YCL025C or YDR508C or YKR039W -1000.00 1000.00 0.00 -r_1219 H+[e] + L-tryptophan[e] <=> H+[c] + L-tryptophan[c] YBR068C or YBR069C or YDR046C or YKR039W or YOL020W -1000.00 1000.00 0.00 +r_1213 H+[e] + L-lysine[e] <=> H+[c] + L-lysine[c] YKR039W or YNL268W 0.00 1000.00 0.00 +r_1214 H+[e] + L-methionine[e] <=> H+[c] + L-methionine[c] YBR068C or YCL025C or YDR046C or YDR508C or YGR055W or YHL036W or YKR039W 0.00 1000.00 0.00 +r_1215 H+[e] + L-phenylalanine[e] <=> H+[c] + L-phenylalanine[c] YBR068C or YCL025C or YDR046C or YKR039W or YOL020W 0.00 1000.00 0.00 +r_1216 H+[e] + L-proline[e] <=> H+[c] + L-proline[c] YKR039W or YOR348C 0.00 1000.00 0.00 +r_1217 H+[e] + L-serine[e] <=> H+[c] + L-serine[c] YCL025C or YDR508C or YFL055W or YKR039W or YPL265W or YDR105C 0.00 1000.00 0.00 +r_1218 H+[e] + L-threonine[e] <=> H+[c] + L-threonine[c] YCL025C or YDR508C or YKR039W 0.00 1000.00 0.00 +r_1219 H+[e] + L-tryptophan[e] <=> H+[c] + L-tryptophan[c] YBR068C or YBR069C or YDR046C or YKR039W or YOL020W 0.00 1000.00 0.00 r_1220 L-tyrosine[v] <=> L-tyrosine[c] YCL038C -1000.00 1000.00 0.00 r_1221 H+[v] + L-tyrosine[c] => H+[c] + L-tyrosine[v] YBR293W or YJR001W 0.00 1000.00 0.00 r_1222 H+[v] + L-tyrosine[v] => H+[c] + L-tyrosine[c] YKL146W or YNL101W 0.00 1000.00 0.00 -r_1223 H+[e] + L-tyrosine[e] <=> H+[c] + L-tyrosine[c] YBR068C or YBR069C or YCL025C or YDR046C or YKR039W or YOL020W -1000.00 1000.00 0.00 -r_1224 H+[e] + L-valine[e] <=> H+[c] + L-valine[c] YBR068C or YBR069C or YCL025C or YDR046C or YKR039W -1000.00 1000.00 0.00 +r_1223 H+[e] + L-tyrosine[e] <=> H+[c] + L-tyrosine[c] YBR068C or YBR069C or YCL025C or YDR046C or YKR039W or YOL020W 0.00 1000.00 0.00 +r_1224 H+[e] + L-valine[e] <=> H+[c] + L-valine[c] YBR068C or YBR069C or YCL025C or YDR046C or YKR039W 0.00 1000.00 0.00 r_1225 lanosterol[e] <=> lanosterol[c] YIL013C or YOR011W -1000.00 1000.00 0.00 r_1226 (S)-malate[c] + phosphate[m] => (S)-malate[m] + phosphate[c] YLR348C 0.00 1000.00 0.00 r_1227 H+[e] + maltose[e] => H+[c] + maltose[c] YBR298C or YDL247W or YGR289C or YJR160C 0.00 1000.00 0.00 @@ -966,27 +965,27 @@ r_1232 dGMP[m] + NAD[c] => dGMP[c] + NAD[m] YIL006W 0.00 1000.00 0.00 r_1235 nicotinate[e] <=> nicotinate[c] YGR260W -1000.00 1000.00 0.00 r_1236 stearate[c] <=> stearate[p] YKL188C and YPL147W -1000.00 1000.00 0.00 r_1237 H+[c] + ornithine[m] => H+[m] + ornithine[c] YOR130C 0.00 1000.00 0.00 -r_1238 H+[e] + ornithine[e] <=> H+[c] + ornithine[c] YKR039W -1000.00 1000.00 0.00 +r_1238 H+[e] + ornithine[e] <=> H+[c] + ornithine[c] YKR039W 0.00 1000.00 0.00 r_1239 H+[c] + oxaloacetate[c] => H+[m] + oxaloacetate[m] YKL120W 0.00 1000.00 0.00 -r_1241 (R)-pantothenate[e] + H+[e] <=> (R)-pantothenate[c] + H+[c] YCR028C -1000.00 1000.00 0.00 +r_1241 (R)-pantothenate[e] + H+[e] <=> (R)-pantothenate[c] + H+[c] YCR028C 0.00 1000.00 0.00 r_1242 pentaprenyl diphosphate[c] <=> pentaprenyl diphosphate[m] -1000.00 1000.00 0.00 r_1243 phenethyl acetate[c] => phenethyl acetate[e] 0.00 1000.00 0.00 -r_1244 H+[e] + phosphate[e] <=> H+[c] + phosphate[c] YBR296C or YCR037C or YJL198W or YML123C or YNR013C -1000.00 1000.00 0.00 +r_1244 H+[e] + phosphate[e] <=> H+[c] + phosphate[c] YBR296C or YCR037C or YJL198W or YML123C or YNR013C 0.00 1000.00 0.00 r_1245 H+[c] + phosphate[c] => H+[m] + phosphate[m] YER053C or YJR077C 0.00 1000.00 0.00 -r_1249 H+[e] + potassium[e] <=> H+[c] + potassium[c] YDR456W or YJL129C -1000.00 1000.00 0.00 +r_1249 H+[e] + potassium[e] <=> H+[c] + potassium[c] YDR456W or YJL129C 0.00 1000.00 0.00 r_1250 putrescine[c] => putrescine[e] YKL174C 0.00 0.00 0.00 -r_1251 H+[c] + putrescine[e] <=> H+[e] + putrescine[c] YLL028W or YOR273C -1000.00 1000.00 0.00 +r_1251 H+[c] + putrescine[e] <=> H+[e] + putrescine[c] YLL028W or YOR273C -1000.00 0.00 0.00 r_1252 H+[v] + putrescine[c] <=> H+[c] + putrescine[v] YLL028W or YOR273C -1000.00 1000.00 0.00 -r_1253 H+[e] + pyridoxine[e] <=> H+[c] + pyridoxine[c] YGL186C -1000.00 1000.00 0.00 -r_1254 H+[e] + pyruvate[e] <=> H+[c] + pyruvate[c] YKL217W -1000.00 1000.00 0.00 +r_1253 H+[e] + pyridoxine[e] <=> H+[c] + pyridoxine[c] YGL186C 0.00 1000.00 0.00 +r_1254 H+[e] + pyruvate[e] <=> H+[c] + pyruvate[c] YKL217W 0.00 1000.00 0.00 r_1255 H+[e] + S-adenosyl-L-methionine[e] => H+[c] + S-adenosyl-L-methionine[c] YPL274W 0.00 1000.00 0.00 r_1256 S-adenosyl-L-methionine[c] <=> S-adenosyl-L-methionine[m] YNL003C -1000.00 1000.00 0.00 r_1257 H+[e] + S-methyl-L-methionine[e] => H+[c] + S-methyl-L-methionine[c] YLL061W 0.00 1000.00 0.00 r_1258 H+[e] + sodium[c] <=> H+[c] + sodium[e] YDR456W or YLR138W -1000.00 1000.00 0.00 r_1259 spermidine[c] => spermidine[e] YKL174C 0.00 0.00 0.00 -r_1260 H+[c] + spermidine[e] <=> H+[e] + spermidine[c] YBR132C or YHL016C or YKR039W or YLL028W or YOR273C or YPL274W -1000.00 1000.00 0.00 +r_1260 H+[c] + spermidine[e] <=> H+[e] + spermidine[c] YBR132C or YHL016C or YKR039W or YLL028W or YOR273C or YPL274W -1000.00 0.00 0.00 r_1261 H+[v] + spermidine[c] <=> H+[c] + spermidine[v] YLL028W or YOR273C -1000.00 1000.00 0.00 -r_1262 H+[c] + spermine[e] <=> H+[e] + spermine[c] YGR138C or YLL028W or YOR273C or YPR156C -1000.00 1000.00 0.00 +r_1262 H+[c] + spermine[e] <=> H+[e] + spermine[c] YGR138C or YLL028W or YOR273C or YPR156C -1000.00 0.00 0.00 r_1263 H+[v] + spermine[c] <=> H+[c] + spermine[v] YGR138C or YLL028W or YOR273C or YPR156C -1000.00 1000.00 0.00 r_1264 phosphate[m] + succinate[c] => phosphate[c] + succinate[m] YLR348C 0.00 1000.00 0.00 r_1265 fumarate[m] + succinate[c] => fumarate[c] + succinate[m] YJR095W 0.00 1000.00 0.00 @@ -997,7 +996,7 @@ r_1269 TDP[c] => TDP[m] YGR096W 0.00 1000.00 0.00 r_1270 H+[e] + thiamine[e] => H+[c] + thiamine[c] YLR237W or YOR071C or YOR192C 0.00 1000.00 0.00 r_1271 UDP-D-galactose[c] => UDP-D-galactose[g] YPL244C 0.00 1000.00 0.00 r_1272 H+[e] + uracil[e] => H+[c] + uracil[c] YBR021W 0.00 1000.00 0.00 -r_1273 2 H+[e] + urea[e] <=> 2 H+[c] + urea[c] YHL016C -1000.00 1000.00 0.00 +r_1273 2 H+[e] + urea[e] <=> 2 H+[c] + urea[c] YHL016C 0.00 1000.00 0.00 r_1274 H+[e] + uridine[e] => H+[c] + uridine[c] YBL042C 0.00 1000.00 0.00 r_1275 FMN[m] + H+[c] + UMP[m] + UTP[c] => FMN[c] + H+[m] + UMP[c] + UTP[m] YBR192W 0.00 1000.00 0.00 r_1276 2 H+[c] + UMP[m] + UTP[c] => 2 H+[m] + UMP[c] + UTP[m] YBR192W 0.00 1000.00 0.00 @@ -1079,7 +1078,7 @@ r_1598 3-methylbutanal[e] => 0.00 1000.00 0.00 r_1599 3-methylbutanal[c] <=> 3-methylbutanal[e] -1000.00 1000.00 0.00 r_1600 3-methylbutanal[c] <=> 3-methylbutanal[m] -1000.00 1000.00 0.00 r_1601 3-hexaprenyl-4-hydroxybenzoic acid[c] <=> 3-hexaprenyl-4-hydroxybenzoic acid[m] -1000.00 1000.00 0.00 -r_1603 5'-phosphoribosyl-5-aminoimidazole[c] => 4-amino-5-hydroxymethyl-2-methylpyrimidine[c] + glycolaldehyde[c] + H+[c] + phosphate[c] YFL058W 0.00 1000.00 0.00 +r_1603 5'-phosphoribosyl-5-aminoimidazole[c] + H+[c] => 4-amino-5-hydroxymethyl-2-methylpyrimidine[c] + glycolaldehyde[c] + phosphate[c] YFL058W 0.00 1000.00 0.00 r_1604 4-aminobenzoate[e] => 0.00 1000.00 0.00 r_1605 4-aminobenzoate[c] <=> 4-aminobenzoate[e] -1000.00 1000.00 0.00 r_1606 4-aminobenzoate[c] <=> 4-aminobenzoate[m] -1000.00 1000.00 0.00 @@ -1470,7 +1469,7 @@ r_2072 L-threonine[c] => L-threonine[m] YDR508C 0.00 1000.00 0.00 r_2073 thymidine[e] => 0.00 1000.00 0.00 r_2074 ATP[c] + thymidine[c] => ADP[c] + dTMP[c] + H+[c] 0.00 1000.00 0.00 r_2075 thymidine[e] <=> thymidine[c] -1000.00 1000.00 0.00 -r_2079 H+[c] + trehalose[c] <=> H+[e] + trehalose[e] YGR289C -1000.00 1000.00 0.00 +r_2079 H+[c] + trehalose[c] <=> H+[e] + trehalose[e] YGR289C -1000.00 0.00 0.00 r_2080 trehalose[c] <=> trehalose[v] -1000.00 1000.00 0.00 r_2082 L-tryptophan[c] => L-tryptophan[m] 0.00 1000.00 0.00 r_2083 tryptophol[e] => 0.00 1000.00 0.00 @@ -1518,9 +1517,9 @@ r_2137 ergosta-5,7,22,24(28)-tetraen-3beta-ol[e] => 0.00 1000.00 0.00 r_2139 ergosta-5,7,22,24(28)-tetraen-3beta-ol[e] <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol[c] -1000.00 1000.00 0.00 r_2140 acetyl-CoA[c] + 21 H+[c] + 7 malonyl-CoA[c] + 14 NADPH[c] => 7 carbon dioxide[c] + 7 coenzyme A[c] + 7 H2O[c] + 14 NADP(+)[c] + palmitoyl-CoA[c] YKL182W and YPL231W 0.00 1000.00 0.00 r_2141 acetyl-CoA[c] + 24 H+[c] + 8 malonyl-CoA[c] + 16 NADPH[c] => 8 carbon dioxide[c] + 8 coenzyme A[c] + 8 H2O[c] + 16 NADP(+)[c] + stearoyl-CoA[c] YKL182W and YPL231W 0.00 1000.00 0.00 -r_2142 acetyl-ACP[m] + carboxyacetyl-ACP[m] + H+[m] => carbon dioxide[m] + ACP1[m] + acetoacetyl-ACP[m] YER061C and YKL192C 0.00 1000.00 0.00 -r_2143 carboxyacetyl-ACP[m] + H+[m] + butanoyl-ACP[m] => carbon dioxide[m] + ACP1[m] + 3-oxo-hexanoyl-ACP[m] YER061C and YKL192C 0.00 1000.00 0.00 -r_2144 carboxyacetyl-ACP[m] + H+[m] + hexanoyl-ACP[m] => carbon dioxide[m] + ACP1[m] + 3-oxo-octanoyl-ACP[m] YER061C and YKL192C 0.00 1000.00 0.00 +r_2142 acetyl-ACP[m] + carboxyacetyl-ACP[m] => carbon dioxide[m] + ACP1[m] + acetoacetyl-ACP[m] YER061C and YKL192C 0.00 1000.00 0.00 +r_2143 carboxyacetyl-ACP[m] + butanoyl-ACP[m] => carbon dioxide[m] + ACP1[m] + 3-oxo-hexanoyl-ACP[m] YER061C and YKL192C 0.00 1000.00 0.00 +r_2144 carboxyacetyl-ACP[m] + hexanoyl-ACP[m] => carbon dioxide[m] + ACP1[m] + 3-oxo-octanoyl-ACP[m] YER061C and YKL192C 0.00 1000.00 0.00 r_2145 H+[m] + NADPH[m] + acetoacetyl-ACP[m] => NADP(+)[m] + 3-hydroxybutanoyl-ACP[m] YKL055C 0.00 1000.00 0.00 r_2146 H+[m] + NADPH[m] + 3-oxo-hexanoyl-ACP[m] => NADP(+)[m] + 3-hydroxyhexanoyl-ACP[m] YKL055C 0.00 1000.00 0.00 r_2147 H+[m] + NADPH[m] + 3-oxo-octanoyl-ACP[m] => NADP(+)[m] + 3-hydroxyoctanoyl-ACP[m] YKL055C 0.00 1000.00 0.00 @@ -1608,11 +1607,11 @@ r_2228 ATP[c] + H2O[c] + hexacosanoyl-CoA[c] => ADP[c] + H+[c] + hexacosanoyl-Co r_2229 butyrate[c] <=> butyrate[p] -1000.00 1000.00 0.00 r_2230 hexanoate[c] <=> hexanoate[p] -1000.00 1000.00 0.00 r_2231 oleate[c] <=> oleate[p] YKL188C and YPL147W -1000.00 1000.00 0.00 -r_2232 H2O[p] + butanoyl-CoA[p] => coenzyme A[p] + 5 H+[p] + butyrate[p] YJR019C 0.00 1000.00 0.00 +r_2232 H2O[p] + butanoyl-CoA[p] => coenzyme A[p] + H+[p] + butyrate[p] YJR019C 0.00 1000.00 0.00 r_2233 H2O[p] + hexanoyl-CoA[p] => coenzyme A[p] + 5 H+[p] + hexanoate[p] YJR019C 0.00 1000.00 0.00 r_2234 H2O[p] + palmitoleoyl-CoA(4-)[p] => coenzyme A[p] + H+[p] + palmitoleate[p] YJR019C 0.00 1000.00 0.00 r_2235 H2O[p] + oleoyl-CoA[p] => coenzyme A[p] + H+[p] + oleate[p] YJR019C 0.00 1000.00 0.00 -r_2236 oxygen[p] + butanoyl-CoA[p] => hydrogen peroxide[p] + but-2-enoyl-CoA[p] YGL205W 0.00 1000.00 0.00 +r_2236 oxygen[p] + butanoyl-CoA[p] => hydrogen peroxide[p] + trans-but-2-enoyl-CoA[p] YGL205W 0.00 1000.00 0.00 r_2237 oxygen[p] + hexanoyl-CoA[p] => hydrogen peroxide[p] + trans-hex-2-enoyl-CoA[p] YGL205W 0.00 1000.00 0.00 r_2238 octanoyl-CoA[p] + oxygen[p] => hydrogen peroxide[p] + trans-oct-2-enoyl-CoA[p] YGL205W 0.00 1000.00 0.00 r_2239 oxygen[p] + icosanoyl-CoA[p] => hydrogen peroxide[p] + trans-icos-2-enoyl-CoA[p] YGL205W 0.00 1000.00 0.00 @@ -1630,7 +1629,7 @@ r_2250 H2O[p] + trans-tetradec-2-enoyl-CoA[p] => (S)-3-hydroxytetradecanoyl-CoA[ r_2251 H2O[p] + hexadec-2-enoyl-CoA[p] => (S)-3-hydroxypalmitoyl-CoA[p] YKR009C 0.00 1000.00 0.00 r_2252 H2O[p] + trans-octadec-2-enoyl-CoA[p] => 3-hydroxyoctadecanoyl-CoA[p] YKR009C 0.00 1000.00 0.00 r_2253 H2O[p] + trans-hexacos-2-enoyl-CoA[p] => (S)-3-hydroxyhexacosanoyl-CoA[p] YKR009C 0.00 1000.00 0.00 -r_2254 H2O[p] + but-2-enoyl-CoA[p] => 4 H+[p] + (R)-3-hydroxybutanoyl-CoA[p] YKR009C 0.00 1000.00 0.00 +r_2254 H2O[p] + trans-but-2-enoyl-CoA[p] => (R)-3-hydroxybutanoyl-CoA[p] YKR009C 0.00 1000.00 0.00 r_2255 H2O[p] + trans-hex-2-enoyl-CoA[p] => (R)-3-hydroxyhexanoyl-CoA[p] YKR009C 0.00 1000.00 0.00 r_2256 4 H+[p] + H2O[p] + trans-oct-2-enoyl-CoA[p] => (R)-3-hydroxyoctanoyl-CoA[p] YKR009C 0.00 1000.00 0.00 r_2257 H2O[p] + trans-icos-2-enoyl-CoA[p] => (R)-3-hydroxyicosanoyl-CoA[p] YKR009C 0.00 1000.00 0.00 @@ -1660,7 +1659,7 @@ r_2280 NAD[p] + (R)-3-hydroxy-cis-octadec-9-enoyl-CoA[p] => H+[p] + NADH[p] + 3- r_2281 NAD[p] + (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA[p] => H+[p] + NADH[p] + 3-oxo-cis-hexadec-7-enoyl-CoA[p] YKR009C 0.00 1000.00 0.00 r_2282 NAD[p] + (R)-3-hydroxy-cis-tetradec-5-enoyl-CoA[p] => H+[p] + NADH[p] + 3-oxo-cis-tetradec-5-enoyl-CoA[p] YKR009C 0.00 1000.00 0.00 r_2283 coenzyme A[p] + acetoacetyl-CoA[p] => 2 acetyl-CoA[p] YIL160C 0.00 1000.00 0.00 -r_2284 coenzyme A[p] + 3-oxohexanoyl-CoA[p] => acetyl-CoA[p] + butanoyl-CoA[p] YIL160C 0.00 1000.00 0.00 +r_2284 coenzyme A[p] + 3-oxohexanoyl-CoA[p] => acetyl-CoA[p] + 4 H+[p] + butanoyl-CoA[p] YIL160C 0.00 1000.00 0.00 r_2285 coenzyme A[p] + 3-oxooctanoyl-CoA[p] => acetyl-CoA[p] + hexanoyl-CoA[p] YIL160C 0.00 1000.00 0.00 r_2286 coenzyme A[p] + 3-oxoicosanoyl-CoA[p] => acetyl-CoA[p] + stearoyl-CoA[p] YIL160C 0.00 1000.00 0.00 r_2287 coenzyme A[p] + 3-oxodocosanoyl-CoA[p] => acetyl-CoA[p] + icosanoyl-CoA[p] YIL160C 0.00 1000.00 0.00 @@ -1707,11 +1706,11 @@ r_2329 H+[lp] + acylglycerone phosphate (16:1)[lp] + NADPH[lp] => 1-acyl-sn-glyc r_2330 H+[lp] + acylglycerone phosphate (18:0)[lp] + NADPH[lp] => 1-acyl-sn-glycerol 3-phosphate (18:0)[lp] + NADP(+)[lp] YIL124W 0.00 1000.00 0.00 r_2331 H+[lp] + acylglycerone phosphate (18:1)[lp] + NADPH[lp] => 1-acyl-sn-glycerol 3-phosphate (18:1)[lp] + NADP(+)[lp] YIL124W 0.00 1000.00 0.00 r_2332 palmitoleoyl-CoA(4-)[erm] + 1-acyl-sn-glycerol 3-phosphate (16:0)[erm] => coenzyme A[erm] + phosphatidate (1-16:0, 2-16:1)[erm] YOR175C 0.00 1000.00 0.00 -r_2333 oleoyl-CoA[erm] + 1-acyl-sn-glycerol 3-phosphate (16:0)[erm] => coenzyme A[erm] + phosphatidate (1-16:0, 2-18:1)[erm] YDL052C or YOR175C 0.00 1000.00 0.00 +r_2333 oleoyl-CoA[erm] + 1-acyl-sn-glycerol 3-phosphate (16:0)[erm] => coenzyme A[erm] + phosphatidate (1-16:0, 2-18:1)[erm] YOR175C or YPR139C 0.00 1000.00 0.00 r_2334 palmitoleoyl-CoA(4-)[erm] + 1-acyl-sn-glycerol 3-phosphate (16:1)[erm] => coenzyme A[erm] + phosphatidate (1-16:1, 2-16:1)[erm] YOR175C 0.00 1000.00 0.00 -r_2335 oleoyl-CoA[erm] + 1-acyl-sn-glycerol 3-phosphate (16:1)[erm] => coenzyme A[erm] + phosphatidate (1-16:1, 2-18:1)[erm] YDL052C or YOR175C 0.00 1000.00 0.00 +r_2335 oleoyl-CoA[erm] + 1-acyl-sn-glycerol 3-phosphate (16:1)[erm] => coenzyme A[erm] + phosphatidate (1-16:1, 2-18:1)[erm] YOR175C or YPR139C 0.00 1000.00 0.00 r_2336 palmitoleoyl-CoA(4-)[erm] + 1-acyl-sn-glycerol 3-phosphate (18:0)[erm] => coenzyme A[erm] + phosphatidate (1-18:0, 2-16:1)[erm] YOR175C 0.00 1000.00 0.00 -r_2337 oleoyl-CoA[erm] + 1-acyl-sn-glycerol 3-phosphate (18:0)[erm] => coenzyme A[erm] + phosphatidate (1-18:0, 2-18:1)[erm] YDL052C or YOR175C 0.00 1000.00 0.00 +r_2337 oleoyl-CoA[erm] + 1-acyl-sn-glycerol 3-phosphate (18:0)[erm] => coenzyme A[erm] + phosphatidate (1-18:0, 2-18:1)[erm] YOR175C or YPR139C 0.00 1000.00 0.00 r_2338 palmitoleoyl-CoA(4-)[erm] + 1-acyl-sn-glycerol 3-phosphate (18:1)[erm] => coenzyme A[erm] + phosphatidate (1-18:1, 2-16:1)[erm] YOR175C 0.00 1000.00 0.00 r_2339 oleoyl-CoA[erm] + 1-acyl-sn-glycerol 3-phosphate (18:1)[erm] => coenzyme A[erm] + phosphatidate (1-18:1, 2-18:1)[erm] YDL052C or YOR175C 0.00 1000.00 0.00 r_2340 oleoyl-CoA[lp] + 1-acyl-sn-glycerol 3-phosphate (16:0)[lp] => coenzyme A[lp] + phosphatidate (1-16:0, 2-18:1)[lp] YDL052C or YKR089C or YOR081C 0.00 1000.00 0.00 @@ -1815,11 +1814,11 @@ r_2437 H+[erm] + phosphatidate (1-16:1, 2-18:1)[erm] + CTP[erm] <=> diphosphate[ r_2438 H+[erm] + phosphatidate (1-18:0, 2-18:1)[erm] + CTP[erm] <=> diphosphate[erm] + CDP-diacylglycerol (1-18:0, 2-18:1)[erm] YBR029C -1000.00 1000.00 0.00 r_2439 H+[erm] + phosphatidate (1-18:1, 2-18:1)[erm] + CTP[erm] <=> diphosphate[erm] + CDP-diacylglycerol (1-18:1, 2-18:1)[erm] YBR029C -1000.00 1000.00 0.00 r_2440 phosphatidate (1-16:0, 2-16:1)[mm] + CTP[mm] + H+[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-16:0, 2-16:1)[mm] YBR029C -1000.00 1000.00 0.00 -r_2441 CTP[mm] + H+[mm] + phosphatidate (1-16:1, 2-16:1)[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-16:1, 2-16:1)[mm] YBR029C -1000.00 1000.00 0.00 -r_2442 CTP[mm] + H+[mm] + phosphatidate (1-18:0, 2-16:1)[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-18:0, 2-16:1)[mm] YBR029C -1000.00 1000.00 0.00 -r_2443 CTP[mm] + H+[mm] + phosphatidate (1-18:1, 2-16:1)[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-18:1, 2-16:1)[mm] YBR029C -1000.00 1000.00 0.00 -r_2444 CTP[mm] + H+[mm] + phosphatidate (1-16:0, 2-18:1)[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-16:0, 2-18:1)[mm] YBR029C -1000.00 1000.00 0.00 -r_2445 CTP[mm] + H+[mm] + phosphatidate (1-16:1, 2-18:1)[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-16:1, 2-18:1)[mm] YBR029C -1000.00 1000.00 0.00 +r_2441 CTP[mm] + H+[mm] + phosphatidate (1-16:1, 2-16:1)[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-16:1, 2-16:1)[mm] YGR046W -1000.00 1000.00 0.00 +r_2442 CTP[mm] + H+[mm] + phosphatidate (1-18:0, 2-16:1)[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-18:0, 2-16:1)[mm] YGR046W -1000.00 1000.00 0.00 +r_2443 CTP[mm] + H+[mm] + phosphatidate (1-18:1, 2-16:1)[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-18:1, 2-16:1)[mm] YGR046W -1000.00 1000.00 0.00 +r_2444 CTP[mm] + H+[mm] + phosphatidate (1-16:0, 2-18:1)[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-16:0, 2-18:1)[mm] YGR046W -1000.00 1000.00 0.00 +r_2445 CTP[mm] + H+[mm] + phosphatidate (1-16:1, 2-18:1)[mm] <=> diphosphate[mm] + CDP-diacylglycerol (1-16:1, 2-18:1)[mm] YGR046W -1000.00 1000.00 0.00 r_2446 CDP-diacylglycerol (1-16:0, 2-16:1)[erm] + L-serine[erm] => 2 H+[erm] + CMP[erm] + phosphatidyl-L-serine (1-16:0, 2-16:1)[erm] YER026C 0.00 1000.00 0.00 r_2447 CDP-diacylglycerol (1-16:1, 2-16:1)[erm] + L-serine[erm] => 2 H+[erm] + CMP[erm] + phosphatidyl-L-serine (1-16:1, 2-16:1)[erm] YER026C 0.00 1000.00 0.00 r_2448 CDP-diacylglycerol (1-18:0, 2-16:1)[erm] + L-serine[erm] => 2 H+[erm] + CMP[erm] + phosphatidyl-L-serine (1-18:0, 2-16:1)[erm] YER026C 0.00 1000.00 0.00 @@ -3338,10 +3337,10 @@ r_3970 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1)[c] => 0.86312 1-phosphati r_3971 ergosteryl palmitoleate[erm] => 0.63305 ergosterol ester backbone[erm] + 0.25441 C16:1 chain[c] 0.00 1000.00 0.00 r_3972 ergosteryl oleate[erm] => 0.66111 ergosterol ester backbone[erm] + 0.28247 C18:1 chain[c] 0.00 1000.00 0.00 r_3973 ergosterol ester backbone[erm] <=> ergosterol ester backbone[c] -1000.00 1000.00 0.00 -r_3975 palmitate[c] => 0.25542 fatty acid backbone[c] + 0.25643 C16:0 chain[c] 0.00 1000.00 0.00 -r_3976 palmitoleate[c] => 0.25341 fatty acid backbone[c] + 0.25441 C16:1 chain[c] 0.00 1000.00 0.00 -r_3977 stearate[c] => 0.28347 fatty acid backbone[c] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 -r_3978 oleate[c] => 0.28146 fatty acid backbone[c] + 0.28247 C18:1 chain[c] 0.00 1000.00 0.00 +r_3975 H+[c] + palmitate[c] => 0.25542 fatty acid backbone[c] + 0.25643 C16:0 chain[c] 0.00 1000.00 0.00 +r_3976 H+[c] + palmitoleate[c] => 0.25341 fatty acid backbone[c] + 0.25441 C16:1 chain[c] 0.00 1000.00 0.00 +r_3977 H+[c] + stearate[c] => 0.28347 fatty acid backbone[c] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 +r_3978 H+[c] + oleate[c] => 0.28146 fatty acid backbone[c] + 0.28247 C18:1 chain[c] 0.00 1000.00 0.00 r_3979 phosphatidyl-L-serine (1-16:0, 2-16:1)[erm] => 0.73396 phosphatidyl-L-serine backbone[erm] + 0.25643 C16:0 chain[c] + 0.25441 C16:1 chain[c] 0.00 1000.00 0.00 r_3980 phosphatidyl-L-serine (1-16:1, 2-16:1)[erm] => 0.73195 phosphatidyl-L-serine backbone[erm] + 0.50883 C16:1 chain[c] 0.00 1000.00 0.00 r_3981 phosphatidyl-L-serine (1-18:0, 2-16:1)[erm] => 0.76202 phosphatidyl-L-serine backbone[erm] + 0.25441 C16:1 chain[c] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 @@ -3404,16 +3403,16 @@ r_4037 triglyceride (1-18:1, 2-18:1, 3-18:1)[erm] => 0.88545 triglyceride backbo r_4038 triglyceride backbone[erm] <=> triglyceride backbone[c] -1000.00 1000.00 0.00 r_4039 acetate[m] + succinyl-CoA[m] <=> acetyl-CoA[m] + succinate[m] YBL015W -1000.00 1000.00 0.00 r_4040 heme a[m] <=> heme a[c] -1000.00 1000.00 0.00 -r_4041 55.3 ATP[c] + 55.3 H2O[c] + lipid[c] + protein[c] + carbohydrate[c] + RNA[c] + DNA[c] + cofactor[c] + ion[c] => 55.3 ADP[c] + biomass[c] + 55.3 H+[c] + 55.3 phosphate[c] 0.00 1000.00 0.00 +r_4041 55.3 ATP[c] + 55.3 H2O[c] + lipid[c] + 3 NADPH[c] + protein[c] + carbohydrate[c] + RNA[c] + DNA[c] + cofactor[c] + ion[c] => 55.3 ADP[c] + biomass[c] + 52.3 H+[c] + 3 NADP(+)[c] + 55.3 phosphate[c] 0.00 1000.00 0.00 r_4042 H2O[e] + raffinose[e] => D-fructose[e] + melibiose[e] 0.00 1000.00 0.00 r_4043 raffinose[e] => 0.00 1000.00 0.00 r_4044 melibiose[e] => 0.00 1000.00 0.00 r_4045 H2O[c] + uridine[c] => D-ribose[c] + uracil[c] YDR400W 0.00 1000.00 0.00 r_4046 ATP[c] + H2O[c] => ADP[c] + H+[c] + phosphate[c] 0.70 0.70 0.00 -r_4047 0.52701 Ala-tRNA(Ala)[c] + 0.18459 Arg-tRNA(Arg)[c] + 0.11682 Asn-tRNA(Asn)[c] + 0.34173 Asp-tRNA(Asp)[c] + 0.0075813 Cys-tRNA(Cys)[c] + 0.12107 Gln-tRNA(Gln)[c] + 0.34667 Glu-tRNA(Glu)[c] + 0.33358 Gly-tRNA(Gly)[c] + 0.076157 His-tRNA(His)[c] + 0.22135 Ile-tRNA(Ile)[c] + 0.34047 Leu-tRNA(Leu)[c] + 0.32875 Lys-tRNA(Lys)[c] + 0.058238 Met-tRNA(Met)[c] + 0.15381 Phe-tRNA(Phe)[c] + 0.18919 Pro-tRNA(Pro)[c] + 0.21296 Ser-tRNA(Ser)[c] + 0.21986 Thr-tRNA(Thr)[c] + 0.032622 Trp-tRNA(Trp)[c] + 0.11716 Tyr-tRNA(Tyr)[c] + 0.30394 Val-tRNA(Val)[c] => 0.52701 tRNA(Ala)[c] + 0.18459 tRNA(Arg)[c] + 0.11682 tRNA(Asn)[c] + 0.34173 tRNA(Asp)[c] + 0.0075813 tRNA(Cys)[c] + 0.12107 tRNA(Gln)[c] + 0.34667 tRNA(Glu)[c] + 0.33358 tRNA(Gly)[c] + 0.076157 tRNA(His)[c] + 0.22135 tRNA(Ile)[c] + 0.34047 tRNA(Leu)[c] + 0.32875 tRNA(Lys)[c] + 0.058238 tRNA(Met)[c] + 0.15381 tRNA(Phe)[c] + 0.18919 tRNA(Pro)[c] + 0.21296 tRNA(Ser)[c] + 0.21986 tRNA(Thr)[c] + 0.032622 tRNA(Trp)[c] + 0.11716 tRNA(Tyr)[c] + 0.30394 tRNA(Val)[c] + protein[c] 0.00 1000.00 0.00 +r_4047 0.34774 Ala-tRNA(Ala)[c] + 0.1943 Arg-tRNA(Arg)[c] + 0.19147 Asn-tRNA(Asn)[c] + 0.24036 Asp-tRNA(Asp)[c] + 0.037559 Cys-tRNA(Cys)[c] + 0.14116 Gln-tRNA(Gln)[c] + 0.29649 Glu-tRNA(Glu)[c] + 0.28375 Gly-tRNA(Gly)[c] + 0.083567 His-tRNA(His)[c] + 0.26549 Ile-tRNA(Ile)[c] + 0.36252 Leu-tRNA(Leu)[c] + 0.3294 Lys-tRNA(Lys)[c] + 0.081497 Met-tRNA(Met)[c] + 0.1668 Phe-tRNA(Phe)[c] + 0.17982 Pro-tRNA(Pro)[c] + 0.27773 Ser-tRNA(Ser)[c] + 0.23517 Thr-tRNA(Thr)[c] + 0.03857 Trp-tRNA(Trp)[c] + 0.12303 Tyr-tRNA(Tyr)[c] + 0.3146 Val-tRNA(Val)[c] => 4.1779 H+[c] + 0.34774 tRNA(Ala)[c] + 0.1943 tRNA(Arg)[c] + 0.19147 tRNA(Asn)[c] + 0.24036 tRNA(Asp)[c] + 0.037559 tRNA(Cys)[c] + 0.14116 tRNA(Gln)[c] + 0.29649 tRNA(Glu)[c] + 0.28375 tRNA(Gly)[c] + 0.083567 tRNA(His)[c] + 0.26549 tRNA(Ile)[c] + 0.36252 tRNA(Leu)[c] + 0.3294 tRNA(Lys)[c] + 0.081497 tRNA(Met)[c] + 0.1668 tRNA(Phe)[c] + 0.17982 tRNA(Pro)[c] + 0.27773 tRNA(Ser)[c] + 0.23517 tRNA(Thr)[c] + 0.03857 tRNA(Trp)[c] + 0.12303 tRNA(Tyr)[c] + 0.3146 tRNA(Val)[c] + protein[c] 0.00 1000.00 0.00 r_4048 0.73914 (1->3)-beta-D-glucan[ce] + 0.24696 (1->6)-beta-D-glucan[ce] + 0.02361 chitin[c] + 0.35689 glycogen[c] + 0.70204 mannan[c] + 0.13655 trehalose[c] => carbohydrate[c] 0.00 1000.00 0.00 -r_4049 0.044535 AMP[c] + 0.043276 CMP[c] + 0.044535 GMP[c] + 0.057992 UMP[c] => RNA[c] 0.00 1000.00 0.00 -r_4050 0.0036 dAMP[c] + 0.0024 dCMP[c] + 0.0024 dGMP[c] + 0.0036 dTMP[c] => DNA[c] 0.00 1000.00 0.00 +r_4049 0.044535 AMP[c] + 0.043276 CMP[c] + 0.044535 GMP[c] + 0.38068 H+[c] + 0.057992 UMP[c] => RNA[c] 0.00 1000.00 0.00 +r_4050 0.0036 dAMP[c] + 0.0024 dCMP[c] + 0.0024 dGMP[c] + 0.0036 dTMP[c] + 0.024 H+[c] => DNA[c] 0.00 1000.00 0.00 r_4051 ceramide backbone[g] => ceramide backbone[c] 0.00 1000.00 0.00 r_4052 inositol phosphomannosylinositol phosphoceramide backbone[g] => inositol phosphomannosylinositol phosphoceramide backbone[c] 0.00 1000.00 0.00 r_4053 inositol-P-ceramide backbone[g] => inositol-P-ceramide backbone[c] 0.00 1000.00 0.00 @@ -3439,10 +3438,10 @@ r_4072 ceramide-3 (C24)[g] => 0.68414 ceramide backbone[g] + 0.28448 C18:0 chain r_4073 ceramide-3 (C26)[g] => 0.71219 ceramide backbone[g] + 0.28448 C18:0 chain[c] + 0.3967 C26:0 chain[c] 0.00 1000.00 0.00 r_4074 ceramide-4 (C24)[g] => 0.70014 ceramide backbone[g] + 0.28448 C18:0 chain[c] + 0.36864 C24:0 chain[c] 0.00 1000.00 0.00 r_4075 ceramide-4 (C26)[g] => 0.72819 ceramide backbone[g] + 0.28448 C18:0 chain[c] + 0.3967 C26:0 chain[c] 0.00 1000.00 0.00 -r_4076 phytosphingosine[er] => 0.31751 long-chain base backbone[er] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 -r_4077 phytosphingosine 1-phosphate[er] => 0.39749 long-chain base phosphate backbone[er] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 -r_4078 sphinganine[er] => 0.30252 long-chain base backbone[er] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 -r_4079 sphinganine 1-phosphate[er] => 0.38049 long-chain base phosphate backbone[er] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 +r_4076 phytosphingosine[er] => H+[c] + 0.31751 long-chain base backbone[er] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 +r_4077 H+[c] + phytosphingosine 1-phosphate[er] => 0.39749 long-chain base phosphate backbone[er] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 +r_4078 sphinganine[er] => H+[c] + 0.30252 long-chain base backbone[er] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 +r_4079 H+[c] + sphinganine 1-phosphate[er] => 0.38049 long-chain base phosphate backbone[er] + 0.28448 C18:0 chain[c] 0.00 1000.00 0.00 r_4080 phosphatidate (1-16:0, 2-16:1)[erm] => 0.64487 phosphatidate backbone[erm] + 0.25643 C16:0 chain[c] + 0.25441 C16:1 chain[c] 0.00 1000.00 0.00 r_4081 phosphatidate (1-16:0, 2-18:1)[erm] => 0.67494 phosphatidate backbone[erm] + 0.25643 C16:0 chain[c] + 0.28247 C18:1 chain[c] 0.00 1000.00 0.00 r_4082 phosphatidate (1-16:1, 2-16:1)[erm] => 0.64487 phosphatidate backbone[erm] + 0.50883 C16:1 chain[c] 0.00 1000.00 0.00 @@ -3536,7 +3535,6 @@ r_4169 D-galactose[c] <=> D-galactose[v] YBR241C -1000.00 1000.00 0.00 r_4170 dolichyl phosphate[er] + UDP-N-acetyl-alpha-D-glucosamine[er] <=> N-Acetyl-D-glucosaminyldiphosphodolichol[er] + UMP[er] YBR243C -1000.00 1000.00 0.00 r_4171 glutathione[c] + H2O[c] => L-cysteinylglycine[c] + L-glutamate[c] YBR281C and YNL191W 0.00 1000.00 0.00 r_4172 ATP[c] + H2O[c] + cadmium(2+)[c] => ADP[c] + H+[c] + phosphate[c] + cadmium(2+)[e] YBR295W 0.00 1000.00 0.00 -r_4173 (sulfur carrier)-H[m] + L-cysteine[m] <=> L-alanine[m] + (sulfur carrier)-SH[m] YCL017C -1000.00 1000.00 0.00 r_4174 cholesterol[er] <=> cholesterol[erm] YCR011C -1000.00 1000.00 0.00 r_4175 NAD[c] + 3-chlorobenzyl alcohol[c] <=> H+[c] + NADH[c] + 3-chlorobenzaldehyde[c] YCR107W or YDL243C or YJR155W or YNL331C or YOL165C or YPL088W -1000.00 1000.00 0.00 r_4176 NAD[c] + 3-hydroxybenzyl alcohol[c] <=> H+[c] + NADH[c] + 3-hydroxybenzaldehyde[c] YCR107W or YDL243C or YJR155W or YNL331C or YOL165C or YPL088W -1000.00 1000.00 0.00 @@ -3555,28 +3553,22 @@ r_4189 4a-Hydroxytetrahydrobiopterin[m] <=> H2O[m] + Dihydrobiopterin[m] YHL018 r_4190 2 H+[m] + 2 superoxide[m] => hydrogen peroxide[m] + oxygen[m] YHR008C 0.00 1000.00 0.00 r_4191 H2O[c] + 2-deoxy-D-glucose 6-phosphate[c] <=> phosphate[c] + 2-deoxy-D-glucose[c] YHR043C or YHR044C -1000.00 1000.00 0.00 r_4192 S-adenosyl-L-methionine[c] + [cytochrome c]-L-lysine[c] <=> H+[c] + S-adenosyl-L-homocysteine[c] + [cytochrome c]-N6-methyl-L-lysine[c] YHR109W -1000.00 1000.00 0.00 -r_4193 S-adenosyl-L-methionine[n] + L-lysine-[histone][n] <=> H+[n] + S-adenosyl-L-homocysteine[n] + N6-methyl-L-lysine-[histone][n] YHR119W or YDR440W or YJL168C -1000.00 1000.00 0.00 r_4194 Zn(2+)[c] <=> Zn(2+)[er] YIL023C -1000.00 1000.00 0.00 r_4195 Zn(2+)[m] <=> Zn(2+)[v] YMR243C or YOR316C -1000.00 1000.00 0.00 -r_4196 NADH[erm] + 2 Ferricytochrome b5[erm] <=> H+[erm] + NAD[erm] + 2 Ferrocytochrome b5[erm] YIL043C or YML125C -1000.00 1000.00 0.00 -r_4197 NADH[m] + 2 Ferricytochrome b5[m] <=> H+[m] + NAD[m] + 2 Ferrocytochrome b5[m] YIL043C or YKL150W or YML125C -1000.00 1000.00 0.00 +r_4196 NADH[erm] + 2 ferricytochrome b5[erm] <=> H+[erm] + NAD[erm] + 2 ferrocytochrome b5[erm] YIL043C or YML125C -1000.00 1000.00 0.00 +r_4197 NADH[m] + 2 ferricytochrome b5[m] <=> H+[m] + NAD[m] + 2 ferrocytochrome b5[m] YIL043C or YKL150W or YML125C -1000.00 1000.00 0.00 r_4198 NADP(+)[c] + (S)-benzoin[c] <=> H+[c] + NADPH[c] + benzil[c] YIR036C -1000.00 1000.00 0.00 -r_4199 RX[er] + glutathione[er] <=> HX[er] + R-S-glutathione[er] YIR038C -1000.00 1000.00 0.00 -r_4200 glutathione[c] + RX[c] <=> HX[c] + R-S-glutathione[c] YMR251W or YKR076W -1000.00 1000.00 0.00 -r_4201 glutathione[m] + RX[m] <=> HX[m] + R-S-glutathione[m] YLL060C -1000.00 1000.00 0.00 r_4202 H2O[c] + L-methionine[c] + TRX1 disulphide[c] <=> H+[c] + TRX1[c] + L-Methionine S-oxide[c] YKL069W -1000.00 1000.00 0.00 r_4203 H2O[v] + Ala-Gly[v] <=> L-alanine[v] + L-glycine[v] YKL103C -1000.00 1000.00 0.00 r_4204 H2O[v] + Ala-Leu[v] <=> L-leucine[v] + L-alanine[v] YKL103C -1000.00 1000.00 0.00 r_4205 ATP[c] + 2 H2O[c] + 5-oxo-L-proline[c] => ADP[c] + H+[c] + L-glutamate[c] + phosphate[c] YKL215C 0.00 1000.00 0.00 r_4206 Threo-3-hydroxy-L-aspartate[c] <=> ammonium[c] + oxaloacetate[c] YKL218C -1000.00 1000.00 0.00 -r_4207 RX[p] + glutathione[p] <=> HX[p] + R-S-glutathione[p] YGR154C -1000.00 1000.00 0.00 r_4208 2 glutathione[c] + dehydroascorbate[c] <=> glutathione disulfide[c] + ascorbate[c] YKR076W -1000.00 1000.00 0.00 r_4209 2 glutathione[p] + dehydroascorbate[p] <=> glutathione disulfide[p] + ascorbate[p] YGR154C -1000.00 1000.00 0.00 r_4210 urea[c] <=> H2O[c] + Cyanamide[c] YFL061W or YNL335W -1000.00 1000.00 0.00 r_4211 glyceraldehyde 3-phosphate[c] + L-glutamine[c] + aldehydo-D-ribose 5-phosphate[c] <=> H+[c] + 3 H2O[c] + L-glutamate[c] + phosphate[c] + pyridoxal 5'-phosphate[c] YFL060C or YNL334C -1000.00 1000.00 0.00 r_4212 D-ribulose 5-phosphate[c] + glyceraldehyde 3-phosphate[c] + L-glutamine[c] <=> H+[c] + 3 H2O[c] + L-glutamate[c] + phosphate[c] + pyridoxal 5'-phosphate[c] YFL059W or YNL333W -1000.00 1000.00 0.00 r_4214 H2O[c] + L-cysteinylglycine[c] <=> L-cysteine[c] + L-glycine[c] YFR044C -1000.00 1000.00 0.00 -r_4215 H2O[c] + R-S-Cysteinylglycine[c] <=> L-glycine[c] + S-Substituted L-cysteine[c] YFR044C -1000.00 1000.00 0.00 r_4216 FMN[c] + H2O[c] <=> phosphate[c] + riboflavin[c] YDL024C -1000.00 1000.00 0.00 r_4217 4 H+[m] + 4 iron(2+)[m] + oxygen[m] <=> 2 H2O[m] + 4 iron(3+)[m] YDL120W -1000.00 1000.00 0.00 r_4218 H2O[c] + Glycyl-tRNA(Ala)[c] <=> H+[c] + L-glycine[c] + tRNA(Ala)[c] YDL219W -1000.00 1000.00 0.00 @@ -3586,42 +3578,33 @@ r_4221 NAD[c] + L-iditol[c] <=> H+[c] + L-sorbose[c] + NADH[c] YDL246C -1000.00 r_4222 ATP[c] + alpha-D-Galactose[c] => ADP[c] + alpha-D-galactose 1-phosphate[c] + H+[c] YDR009W 0.00 1000.00 0.00 r_4223 H2O[m] + 3-hydroxy-2-methylpropanoyl-CoA[m] => coenzyme A[m] + H+[m] + 3-hydroxy-2-methylpropanoate[m] YDR036C 0.00 1000.00 0.00 r_4224 ATP[c] + H2O[c] + sodium[c] => ADP[c] + H+[c] + phosphate[c] + sodium[e] YDR038C or YDR039C or YDR040C 0.00 1000.00 0.00 -r_4225 ATP[c] + H2O[c] + sterols[e] <=> ADP[c] + H+[c] + phosphate[c] + sterols[c] YDR051C or YOL075C -1000.00 1000.00 0.00 r_4226 2-oxoglutarate[c] + L-alanine[c] <=> L-glutamate[c] + pyruvate[c] YDR111C -1000.00 1000.00 0.00 r_4227 H2O[c] + 2-Phenylacetamide[c] <=> ammonium[c] + phenylacetic acid[c] YDR242W -1000.00 1000.00 0.00 r_4228 H2O[c] + (Indol-3-yl)acetamide[c] => ammonium[c] + indole-3-acetate[c] YDR242W 0.00 1000.00 0.00 r_4230 ammonium[c] + Acrylic acid[c] <=> H2O[c] + Acrylamide[c] YDR242W -1000.00 1000.00 0.00 r_4231 H2O[c] + Benzamide[c] <=> ammonium[c] + Benzoate[c] YDR242W -1000.00 1000.00 0.00 r_4232 ATP[c] + D-gluconate[c] <=> 6-phospho-D-gluconate[c] + ADP[c] + H+[c] YDR248C -1000.00 1000.00 0.00 -r_4233 S-adenosyl-L-methionine[c] + Protein C-terminal S-farnesyl-L-cysteine[c] <=> S-adenosyl-L-homocysteine[c] + Protein C-terminal S-farnesyl-L-cysteine methyl ester[c] YDR410C -1000.00 1000.00 0.00 r_4234 UDP-N-acetyl-alpha-D-glucosamine[er] + 1-phosphatidyl-1D-myo-inositol[er] <=> H+[er] + UDP[er] + G00143[er] YDR437W and YGR216C and YNL038W and YPL076W and YPL175W and YPL096C-A -1000.00 1000.00 0.00 r_4236 (R)-lactate[c] + H+[c] <=> H2O[c] + methylglyoxal[c] YDR533C or YMR322C or YOR391C or YPL280W -1000.00 1000.00 0.00 r_4237 H2O[v] + Ca(2+)[c] + ATP[v] => H+[v] + phosphate[v] + Ca(2+)[v] + ADP[v] YGL006W 0.00 1000.00 0.00 r_4238 H2O[g] + Ca(2+)[c] + ATP[g] => H+[g] + phosphate[g] + Ca(2+)[g] + ADP[g] YGL167C 0.00 1000.00 0.00 -r_4239 Arg-tRNA(Arg)[c] + generic protein[c] <=> H+[c] + tRNA(Arg)[c] + L-Arginyl-protein[c] YGL017W -1000.00 1000.00 0.00 r_4241 H2O[er] + G00009[er] <=> G00171[er] + D-glucose[er] YGL027C -1000.00 1000.00 0.00 r_4242 GDP-alpha-D-mannose[er] + G10694[er] <=> H+[er] + GDP[er] + G01813[er] YGL038C -1000.00 1000.00 0.00 r_4243 GDP-alpha-D-mannose[er] + G00003[er] <=> H+[er] + GDP[er] + G00004[er] YGL065C -1000.00 1000.00 0.00 r_4244 GDP-alpha-D-mannose[er] + G00004[er] <=> H+[er] + GDP[er] + G00005[er] YGL065C -1000.00 1000.00 0.00 r_4245 H2O[v] + 2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate[v] => D-mannose 6-phosphate[v] + D-Glycerate[v] YGL156W 0.00 1000.00 0.00 -r_4246 H2O[v] + alpha-D-mannoside[v] => alpha-D-mannopyranose[v] + non glycosylated sugar acceptor[v] YGL156W 0.00 1000.00 0.00 r_4247 ATP[c] + bicarbonate[c] + L-threonine[c] => diphosphate[c] + H2O[c] + L-Threonylcarbamoyladenylate[c] YGL169W 0.00 1000.00 0.00 r_4248 D-Serine[c] => ammonium[c] + pyruvate[c] YGL196W 0.00 1000.00 0.00 r_4249 O-acetyl-L-serine[m] + hydrogen sulfide[m] <=> acetate[m] + L-cysteine[m] YGR012W -1000.00 1000.00 0.00 r_4250 H+[er] + H2O[er] + Dolichyl diphosphate[er] <=> dolichyl phosphate[er] + phosphate[er] YGR036C -1000.00 1000.00 0.00 -r_4251 CTP[m] + H+[m] + phosphatidate[m] <=> diphosphate[m] + CDP-diacylglycerol[m] YGR046W -1000.00 1000.00 0.00 -r_4252 L-glycine[c] + NAD[c] + Sulfur donor[c] <=> 3 H2O[c] + nicotinamide[c] + ADP-5-ethyl-4-methylthiazole-2-carboxylate[c] YGR144W -1000.00 1000.00 0.00 r_4253 H+[er] + Dolichyl beta-D-glucosyl phosphate[er] + G10599[er] <=> dolichyl phosphate[er] + G00008[er] YGR227W -1000.00 1000.00 0.00 r_4254 NADH[c] + 2 oxygen[c] + 2 nitric oxide[c] => H+[c] + NAD[c] + 2 nitrate[c] YGR234W 0.00 1000.00 0.00 r_4255 NADPH[c] + 2 oxygen[c] + 2 nitric oxide[c] => H+[c] + NADP(+)[c] + 2 nitrate[c] YGR234W 0.00 1000.00 0.00 -r_4256 ATP[c] + H+[c] + (R)-Lipoate[c] => diphosphate[c] + Lipoyl-AMP[c] YJL046W 0.00 1000.00 0.00 -r_4258 ATP[c] + (R)-Lipoate[c] + Apoprotein[c] => AMP[c] + diphosphate[c] + Protein N6-(lipoyl)lysine[c] YJL046W 0.00 1000.00 0.00 r_4260 H2O[c] + N-(4-oxoglutarate)-L-cysteinylglycine[c] <=> 2-oxoglutarate[c] + L-cysteinylglycine[c] YJL126W -1000.00 1000.00 0.00 r_4261 H2O[m] + N-(4-oxoglutarate)-L-cysteinylglycine[m] <=> 2-oxoglutarate[m] + L-cysteinylglycine[m] YJL126W -1000.00 1000.00 0.00 r_4262 citrate[m] <=> isocitrate[m] YJL200C -1000.00 1000.00 0.00 r_4263 chloride[g] <=> chloride[c] YJR040W -1000.00 1000.00 0.00 r_4264 fumarate[m] + H+[m] + NADH[m] => NAD[m] + succinate[m] YJR051W 0.00 1000.00 0.00 -r_4265 H2O[c] + ribonucleoside 5'-triphosphate[c] => diphosphate[c] + H+[c] + ribonucleoside 5'-phosphate[c] YJR069C 0.00 1000.00 0.00 r_4266 dATP[c] + H2O[c] => dAMP[c] + diphosphate[c] + H+[c] YJR069C 0.00 1000.00 0.00 r_4267 dGTP[c] + H2O[c] => dGMP[c] + diphosphate[c] + H+[c] YJR069C 0.00 1000.00 0.00 r_4268 dTTP[c] + H2O[c] => diphosphate[c] + dTMP[c] + H+[c] YJR069C 0.00 1000.00 0.00 @@ -3633,11 +3616,7 @@ r_4273 FMNH2[c] + oxygen[c] + Ethylnitronate[c] <=> acetaldehyde[c] + FMN[c] + 2 r_4274 H2O[c] + O-succinyl-L-homoserine[c] => 2-oxobutanoate[c] + ammonium[c] + H+[c] + succinate[c] YLL058W or YML082W 0.00 1000.00 0.00 r_4275 NADPH[c] + 2 iron(3+)[e] <=> H+[c] + 2 iron(2+)[c] + NADP(+)[c] YLR047C or YKL220C or YLR214W or YNR060W or YOL152W or YOR381W or YOR384W -1000.00 1000.00 0.00 r_4276 NADPH[c] + 2 iron(3+)[v] <=> H+[c] + 2 iron(2+)[c] + NADP(+)[c] YLL051C -1000.00 1000.00 0.00 -r_4277 Acyl-CoA[er] + 1-acyl-sn-glycerol 3-phosphate[er] <=> coenzyme A[er] + 1,2-diacyl-sn-glycerol 3-phosphate[er] YLR099C or YPR139C -1000.00 1000.00 0.00 -r_4278 ammonium[c] + ATP[c] + Peptide diphthine[c] => AMP[c] + diphosphate[c] + H+[c] + Peptide diphthamide[c] YLR143W 0.00 1000.00 0.00 r_4279 H2O[p] + 8-oxo-dGTP[p] => diphosphate[p] + H+[p] + 8-oxo-dGMP[p] YLR151C 0.00 1000.00 0.00 -r_4280 octanoyl-ACP[m] + Apoprotein[m] <=> ACP1[m] + Protein N6-(octanoyl)lysine[m] YLR239C -1000.00 1000.00 0.00 -r_4281 Apoprotein[m] + Lipoyl-[acp][m] <=> ACP1[m] + Protein N6-(lipoyl)lysine[m] YLR239C -1000.00 1000.00 0.00 r_4282 ATP[c] + beta-D-Fructose 6-phosphate[c] => ADP[c] + beta-D-fructose 2,6-bisphosphate[c] + H+[c] YLR345W 0.00 1000.00 0.00 r_4283 ATP[c] + D-fructose[c] => ADP[c] + H+[c] + beta-D-Fructose 6-phosphate[c] YLR446W 0.00 1000.00 0.00 r_4284 ATP[c] + beta-D-Glucose[c] => ADP[c] + H+[c] + beta-D-Glucose 6-phosphate[c] YLR446W 0.00 1000.00 0.00 @@ -3662,7 +3641,6 @@ r_4304 H2O[c] + NAD[c] + cis-3-Chloroallyl aldehyde[c] <=> 2 H+[c] + NADH[c] + c r_4305 H2O[c] + NAD[c] + Chloroacetaldehyde[c] <=> 2 H+[c] + NADH[c] + Chloroacetic acid[c] YMR110C -1000.00 1000.00 0.00 r_4306 H2O[c] + NAD[c] + Perillyl aldehyde[c] <=> 2 H+[c] + NADH[c] + Perillic acid[c] YMR110C -1000.00 1000.00 0.00 r_4307 H2O[c] + NAD[c] + 2-trans,6-trans-Farnesal[c] <=> 2 H+[c] + NADH[c] + Farnesoic acid[c] YMR110C -1000.00 1000.00 0.00 -r_4308 H2O[erm] + ATP[erm] + phospholipid[erm] => H+[erm] + phosphate[erm] + phospholipid[gm] + ADP[erm] YMR162C 0.00 1000.00 0.00 r_4309 H2O[c] + 1-oleoyl-sn-glycerol[c] => glycerol[c] + H+[c] + oleate[c] YMR210W 0.00 1000.00 0.00 r_4310 2 GDP-alpha-D-mannose[er] + G00005[er] <=> 2 H+[er] + 2 GDP[er] + G10526[er] YNL048W -1000.00 1000.00 0.00 r_4311 2 GDP-alpha-D-mannose[er] + G10526[er] <=> 2 H+[er] + 2 GDP[er] + G00006[er] YNL048W -1000.00 1000.00 0.00 @@ -3676,10 +3654,7 @@ r_4318 H2O[c] + Isomaltose[c] <=> D-glucose[c] + alpha-D-Glucose[c] YOL157C -10 r_4319 2 H2O[c] + Dextrin[c] <=> 2 D-glucose[c] YOL157C -1000.00 1000.00 0.00 r_4320 H+[er] + Dolichyl beta-D-glucosyl phosphate[er] + G00007[er] <=> dolichyl phosphate[er] + G10598[er] YOR002W -1000.00 1000.00 0.00 r_4321 H+[er] + Dolichyl beta-D-glucosyl phosphate[er] + G10598[er] <=> dolichyl phosphate[er] + G10599[er] YOR067C -1000.00 1000.00 0.00 -r_4322 dolichyl D-mannosyl phosphate[er] + G00149[er] <=> dolichyl phosphate[er] + H+[er] + G00140[er] YOR149C -1000.00 1000.00 0.00 -r_4323 2 S-adenosyl-L-methionine[m] + Protein N6-(octanoyl)lysine[m] + 2 Sulfur donor[m] <=> 2 L-methionine[m] + Protein N6-(lipoyl)lysine[m] + 2 5'-Deoxyadenosine[m] YOR196C -1000.00 1000.00 0.00 -r_4324 octanoyl-ACP[m] + 2 S-adenosyl-L-methionine[m] + 2 Sulfur donor[m] <=> 2 L-methionine[m] + Lipoyl-[acp][m] + 2 5'-Deoxyadenosine[m] YOR196C -1000.00 1000.00 0.00 -r_4325 S-sulfanyl-[L-cysteine desulfurase][m] + [disordered-form [Fe-S] cluster scaffold protein][m] => S-sulfanyl-[cysteine desulfurase]-[disordered-form scaffold protein] complex[m] YOR226C or YPL135W 0.00 1000.00 0.00 +r_4322 dolichyl D-mannosyl phosphate[er] + G00149[er] <=> dolichyl phosphate[er] + G00140[er] YOR149C -1000.00 1000.00 0.00 r_4326 hydrogen cyanide[m] + thiosulfate[m] <=> 2 H+[m] + sulphite[m] + thiocyanate[m] YOR251C or YOR285W or YOR286W -1000.00 1000.00 0.00 r_4327 Mg(2+)[c] <=> Mg(2+)[m] YOR334W or YPL060W -1000.00 1000.00 0.00 r_4328 dolichyl phosphate[er] + UDP-D-glucose[er] <=> 2 H+[er] + UDP[er] + Dolichyl beta-D-glucosyl phosphate[er] YPL227C -1000.00 1000.00 0.00 @@ -3694,75 +3669,74 @@ r_4336 H2O[c] + 2-Oxoglutaramate[c] <=> 2-oxoglutarate[c] + ammonium[c] YLR351C r_4337 ATP[m] + H2O[m] + porphyrin[m] <=> ADP[m] + H+[m] + phosphate[m] + porphyrin[c] YMR301C -1000.00 1000.00 0.00 r_4338 H2O[c] + Starch[c] <=> 2 alpha-D-Glucose[c] YOL157C -1000.00 1000.00 0.00 r_4339 UDP-N-acetyl-alpha-D-glucosamine[er] <=> UDP-N-acetyl-alpha-D-glucosamine[g] YEL004W -1000.00 1000.00 0.00 -r_4340 acetyl-CoA[c] + [protein]-L-lysine[c] <=> coenzyme A[c] + H+[c] + [protein]-N(6)-acetyl-L-lysine[c] YEL066W -1000.00 1000.00 0.00 r_4341 glycerol 2-phosphate(2-)[e] <=> glycerol 2-phosphate(2-)[c] -1000.00 1000.00 0.00 r_4342 H2O[c] + glycerol 2-phosphate(2-)[c] => glycerol[c] + phosphate[c] 0.00 1000.00 0.00 -r_4343 H+[e] + O-phospho-L-threonine[e] <=> H+[c] + O-phospho-L-threonine[c] -1000.00 1000.00 0.00 +r_4343 H+[e] + O-phospho-L-threonine[e] <=> H+[c] + O-phospho-L-threonine[c] 0.00 1000.00 0.00 r_4344 H2O[c] + O-phospho-L-threonine[c] => L-threonine[c] + phosphate[c] 0.00 1000.00 0.00 r_4345 H2O[c] + guanosine 2'-monophosphate[c] => guanosine[c] + phosphate[c] 0.00 1000.00 0.00 -r_4346 H+[e] + guanosine 2'-monophosphate[e] <=> H+[c] + guanosine 2'-monophosphate[c] -1000.00 1000.00 0.00 +r_4346 H+[e] + guanosine 2'-monophosphate[e] <=> H+[c] + guanosine 2'-monophosphate[c] 0.00 1000.00 0.00 r_4347 H2O[c] + 3'-GMP[c] => guanosine[c] + phosphate[c] 0.00 1000.00 0.00 -r_4348 H+[e] + 3'-GMP[e] <=> H+[c] + 3'-GMP[c] -1000.00 1000.00 0.00 -r_4349 H+[e] + 2-phosphoglycolate[e] <=> H+[c] + 2-phosphoglycolate[c] -1000.00 1000.00 0.00 +r_4348 H+[e] + 3'-GMP[e] <=> H+[c] + 3'-GMP[c] 0.00 1000.00 0.00 +r_4349 H+[e] + 2-phosphoglycolate[e] <=> H+[c] + 2-phosphoglycolate[c] 0.00 1000.00 0.00 r_4350 H2O[c] + 2-phosphoglycolate[c] => phosphate[c] + glycolate[c] 0.00 1000.00 0.00 r_4351 H2O[c] + cysteamine S-phosphate[c] => phosphate[c] + cysteamine[c] 0.00 1000.00 0.00 r_4352 cysteamine S-phosphate[e] <=> cysteamine S-phosphate[c] -1000.00 1000.00 0.00 r_4353 oxygen[c] + cysteamine[c] => H+[c] + hypotaurine[c] 0.00 1000.00 0.00 r_4354 H2O[c] + NAD[c] + hypotaurine[c] => H+[c] + NADH[c] + taurine[c] 0.00 1000.00 0.00 r_4355 2-oxobutanoate[c] + L-glutamate[c] <=> 2-oxoglutarate[c] + 2-aminobutanoate[c] -1000.00 1000.00 0.00 -r_4356 H+[e] + 2-aminobutanoate[e] <=> H+[c] + 2-aminobutanoate[c] -1000.00 1000.00 0.00 +r_4356 H+[e] + 2-aminobutanoate[e] <=> H+[c] + 2-aminobutanoate[c] 0.00 1000.00 0.00 r_4357 H2O[c] + uridine 2'-phosphate[c] => phosphate[c] + uridine[c] 0.00 1000.00 0.00 -r_4358 H+[e] + uridine 2'-phosphate[e] <=> H+[c] + uridine 2'-phosphate[c] -1000.00 1000.00 0.00 +r_4358 H+[e] + uridine 2'-phosphate[e] <=> H+[c] + uridine 2'-phosphate[c] 0.00 1000.00 0.00 r_4359 H2O[c] + 3'-UMP[c] => phosphate[c] + uridine[c] 0.00 1000.00 0.00 -r_4360 H+[e] + 3'-UMP[e] <=> H+[c] + 3'-UMP[c] -1000.00 1000.00 0.00 -r_4361 H+[e] + Gly-Met[e] <=> H+[c] + Gly-Met[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4360 H+[e] + 3'-UMP[e] <=> H+[c] + 3'-UMP[c] 0.00 1000.00 0.00 +r_4361 H+[e] + Gly-Met[e] <=> H+[c] + Gly-Met[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4362 H2O[v] + Gly-Met[v] => L-methionine[v] + L-glycine[v] 0.00 1000.00 0.00 r_4363 N-phosphocreatine[c] => phosphate[c] + creatinine[c] 0.00 1000.00 0.00 -r_4364 H+[e] + N-phosphocreatine[e] <=> H+[c] + N-phosphocreatine[c] -1000.00 1000.00 0.00 -r_4365 H+[e] + creatinine[e] <=> H+[c] + creatinine[c] -1000.00 1000.00 0.00 +r_4364 H+[e] + N-phosphocreatine[e] <=> H+[c] + N-phosphocreatine[c] 0.00 1000.00 0.00 +r_4365 H+[e] + creatinine[e] <=> H+[c] + creatinine[c] 0.00 1000.00 0.00 r_4366 ADP[c] + H+[c] + N(omega)-phospho-L-arginine[c] <=> ATP[c] + L-arginine[c] -1000.00 1000.00 0.00 -r_4367 H+[e] + N(omega)-phospho-L-arginine[e] <=> H+[c] + N(omega)-phospho-L-arginine[c] -1000.00 1000.00 0.00 +r_4367 H+[e] + N(omega)-phospho-L-arginine[e] <=> H+[c] + N(omega)-phospho-L-arginine[c] 0.00 1000.00 0.00 r_4368 H2O[c] + O(4)-phospho-L-tyrosine[c] => L-tyrosine[c] + phosphate[c] 0.00 1000.00 0.00 -r_4369 H+[e] + triphosphate[e] <=> H+[c] + triphosphate[c] -1000.00 1000.00 0.00 +r_4369 H+[e] + triphosphate[e] <=> H+[c] + triphosphate[c] 0.00 1000.00 0.00 r_4370 H2O[c] + cytidine 2'-phosphate[c] => cytidine[c] + phosphate[c] 0.00 1000.00 0.00 -r_4371 H+[e] + cytidine 2'-phosphate[e] <=> H+[c] + cytidine 2'-phosphate[c] -1000.00 1000.00 0.00 +r_4371 H+[e] + cytidine 2'-phosphate[e] <=> H+[c] + cytidine 2'-phosphate[c] 0.00 1000.00 0.00 r_4372 H2O[c] + 2',3'-cyclic UMP[c] => H+[c] + uridine 2'-phosphate[c] YGR247W 0.00 1000.00 0.00 -r_4373 H+[e] + 2',3'-cyclic UMP[e] <=> H+[c] + 2',3'-cyclic UMP[c] -1000.00 1000.00 0.00 +r_4373 H+[e] + 2',3'-cyclic UMP[e] <=> H+[c] + 2',3'-cyclic UMP[c] 0.00 1000.00 0.00 r_4374 H2O[c] + 3-sulfino-L-alanine[c] => H+[c] + L-alanine[c] + sulphite[c] 0.00 1000.00 0.00 -r_4375 H+[e] + 3-sulfino-L-alanine[e] <=> H+[c] + 3-sulfino-L-alanine[c] -1000.00 1000.00 0.00 +r_4375 H+[e] + 3-sulfino-L-alanine[e] <=> H+[c] + 3-sulfino-L-alanine[c] 0.00 1000.00 0.00 r_4376 H2O[c] + 3'-AMP[c] => adenosine[c] + phosphate[c] 0.00 1000.00 0.00 r_4377 3'-AMP[e] <=> 3'-AMP[c] -1000.00 1000.00 0.00 r_4378 H2O[c] + 6-O-alpha-D-glucopyranosyl-D-fructofuranose[c] => D-fructose[c] + D-glucose[c] 0.00 1000.00 0.00 -r_4379 H+[e] + 6-O-alpha-D-glucopyranosyl-D-fructofuranose[e] <=> H+[c] + 6-O-alpha-D-glucopyranosyl-D-fructofuranose[c] -1000.00 1000.00 0.00 +r_4379 H+[e] + 6-O-alpha-D-glucopyranosyl-D-fructofuranose[e] <=> H+[c] + 6-O-alpha-D-glucopyranosyl-D-fructofuranose[c] 0.00 1000.00 0.00 r_4380 coenzyme A[c] + H+[c] + N-acetyl-L-cysteine[c] <=> acetyl-CoA[c] + L-cysteine[c] -1000.00 1000.00 0.00 -r_4381 H+[e] + N-acetyl-L-cysteine[e] <=> H+[c] + N-acetyl-L-cysteine[c] -1000.00 1000.00 0.00 +r_4381 H+[e] + N-acetyl-L-cysteine[e] <=> H+[c] + N-acetyl-L-cysteine[c] 0.00 1000.00 0.00 r_4382 2 ferricytochrome c[m] + 2 thiosulfate[c] <=> 2 ferrocytochrome c[m] + tetrathionate[c] -1000.00 1000.00 0.00 r_4383 tetrathionate[e] <=> tetrathionate[c] -1000.00 1000.00 0.00 r_4384 H+[c] + NADPH[c] + 5-dehydro-D-gluconate[c] => NADP(+)[c] + D-gluconate[c] 0.00 1000.00 0.00 -r_4385 H+[e] + 5-dehydro-D-gluconate[e] <=> H+[c] + 5-dehydro-D-gluconate[c] -1000.00 1000.00 0.00 +r_4385 H+[e] + 5-dehydro-D-gluconate[e] <=> H+[c] + 5-dehydro-D-gluconate[c] 0.00 1000.00 0.00 r_4386 H2O[v] + Ala-Asp[v] => L-aspartate[v] + L-alanine[v] 0.00 1000.00 0.00 -r_4387 H+[e] + Ala-Asp[e] <=> H+[c] + Ala-Asp[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4387 H+[e] + Ala-Asp[e] <=> H+[c] + Ala-Asp[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4388 H2O[c] + 2',3'-cyclic CMP[c] => H+[c] + cytidine 2'-phosphate[c] YGR247W 0.00 1000.00 0.00 -r_4389 H+[e] + 2',3'-cyclic CMP[e] <=> H+[c] + 2',3'-cyclic CMP[c] -1000.00 1000.00 0.00 +r_4389 H+[e] + 2',3'-cyclic CMP[e] <=> H+[c] + 2',3'-cyclic CMP[c] 0.00 1000.00 0.00 r_4390 H2O[c] + methyl alpha-D-glucopyranoside[c] <=> D-glucose[c] + methanol[c] -1000.00 1000.00 0.00 r_4391 methanol[c] => methanol[e] 0.00 1000.00 0.00 -r_4392 H+[e] + methyl alpha-D-glucopyranoside[e] <=> H+[c] + methyl alpha-D-glucopyranoside[c] -1000.00 1000.00 0.00 +r_4392 H+[e] + methyl alpha-D-glucopyranoside[e] <=> H+[c] + methyl alpha-D-glucopyranoside[c] 0.00 1000.00 0.00 r_4393 ATP[c] + D-tagatose[c] => ADP[c] + H+[c] + D-tagatofuranose 6-phosphate[c] 0.00 1000.00 0.00 r_4394 D-tagatofuranose 6-phosphate[c] <=> D-fructose 6-phosphate[c] -1000.00 1000.00 0.00 r_4395 D-tagatose[e] <=> D-tagatose[c] YDL245C or YDR342C or YDR343C or YDR345C or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YMR011W or YNR072W or YOL156W -1000.00 1000.00 0.00 r_4396 ATP[c] + coenzyme A[c] + acetoacetate[c] => acetoacetyl-CoA[c] + AMP[c] + diphosphate[c] 0.00 1000.00 0.00 r_4397 H2O[c] + N(alpha)-acetyl-L-methionine[c] <=> acetate[c] + L-methionine[c] -1000.00 1000.00 0.00 -r_4398 H+[e] + Ala-Gln[e] <=> H+[c] + Ala-Gln[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4398 H+[e] + Ala-Gln[e] <=> H+[c] + Ala-Gln[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4399 H+[c] + Ala-Glu[c] <=> H+[v] + Ala-Glu[v] -1000.00 1000.00 0.00 r_4400 H2O[e] + alpha-maltotriose[e] => D-glucose[e] + maltose[e] YBR299W or YGR292W 0.00 1000.00 0.00 r_4401 H+[c] + Ala-Thr[c] <=> H+[v] + Ala-Thr[v] -1000.00 1000.00 0.00 -r_4402 H+[e] + Ala-Thr[e] <=> H+[c] + Ala-Thr[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4402 H+[e] + Ala-Thr[e] <=> H+[c] + Ala-Thr[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4403 H2O[c] + triphosphate[c] => diphosphate[c] + phosphate[c] YHR201C or YDR452W 0.00 1000.00 0.00 -r_4404 H+[e] + Gly-Asn[e] <=> H+[c] + Gly-Asn[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4404 H+[e] + Gly-Asn[e] <=> H+[c] + Gly-Asn[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4405 glycerol 1-phosphate[e] <=> glycerol 1-phosphate[c] -1000.00 1000.00 0.00 -r_4406 H+[e] + O-phosphonatooxy-D-serine(2-)[e] <=> H+[c] + O-phosphonatooxy-D-serine(2-)[c] -1000.00 1000.00 0.00 +r_4406 H+[e] + O-phosphonatooxy-D-serine(2-)[e] <=> H+[c] + O-phosphonatooxy-D-serine(2-)[c] 0.00 1000.00 0.00 r_4407 H2O[c] + O-phosphonatooxy-D-serine(2-)[c] <=> phosphate[c] + D-Serine[c] -1000.00 1000.00 0.00 -r_4408 H+[e] + Ala-Glu[e] <=> H+[c] + Ala-Glu[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4408 H+[e] + Ala-Glu[e] <=> H+[c] + Ala-Glu[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4409 H2O[v] + Ala-Glu[v] => L-glutamate[v] + L-alanine[v] 0.00 1000.00 0.00 r_4410 3-oxalomalate(3-)[c] <=> glyoxylate[c] + oxaloacetate[c] -1000.00 1000.00 0.00 r_4411 H2O[c] + L-cysteate[c] => ammonium[c] + H+[c] + pyruvate[c] + sulphite[c] 0.00 1000.00 0.00 @@ -3773,17 +3747,17 @@ r_4415 H2O[v] + Ala-His[v] => L-histidine[v] + L-alanine[v] 0.00 1000.00 0 r_4416 H2O[v] + Ala-Thr[v] => L-alanine[v] + L-threonine[v] 0.00 1000.00 0.00 r_4417 H2O[v] + Gly-Asn[v] => L-asparagine[v] + L-glycine[v] 0.00 1000.00 0.00 r_4418 H2O[v] + Gly-Gln[v] => L-glutamine[v] + L-glycine[v] 0.00 1000.00 0.00 -r_4419 H+[e] + L-cysteate[e] <=> H+[c] + L-cysteate[c] -1000.00 1000.00 0.00 +r_4419 H+[e] + L-cysteate[e] <=> H+[c] + L-cysteate[c] 0.00 1000.00 0.00 r_4420 H2O[e] + turanose[e] <=> D-fructose[e] + D-glucose[e] YBR299W or YGR292W -1000.00 1000.00 0.00 -r_4421 H+[e] + 2-hydroxyethane-1-sulfonate[e] <=> H+[c] + 2-hydroxyethane-1-sulfonate[c] -1000.00 1000.00 0.00 -r_4422 H+[e] + 3-oxalomalate(3-)[e] <=> H+[c] + 3-oxalomalate(3-)[c] -1000.00 1000.00 0.00 +r_4421 H+[e] + 2-hydroxyethane-1-sulfonate[e] <=> H+[c] + 2-hydroxyethane-1-sulfonate[c] 0.00 1000.00 0.00 +r_4422 H+[e] + 3-oxalomalate(3-)[e] <=> H+[c] + 3-oxalomalate(3-)[c] 0.00 1000.00 0.00 r_4423 H+[c] + Gly-Met[c] <=> H+[v] + Gly-Met[v] -1000.00 1000.00 0.00 -r_4424 H+[e] + Gly-Gln[e] <=> H+[c] + Gly-Gln[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4424 H+[e] + Gly-Gln[e] <=> H+[c] + Gly-Gln[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4425 H+[c] + Gly-Gln[c] <=> H+[v] + Gly-Gln[v] -1000.00 1000.00 0.00 r_4426 H+[c] + Ala-Gln[c] <=> H+[v] + Ala-Gln[v] -1000.00 1000.00 0.00 -r_4427 H+[e] + N(alpha)-acetyl-L-methionine[e] <=> H+[c] + N(alpha)-acetyl-L-methionine[c] -1000.00 1000.00 0.00 -r_4428 H+[e] + O(4)-phospho-L-tyrosine[e] <=> H+[c] + O(4)-phospho-L-tyrosine[c] -1000.00 1000.00 0.00 -r_4429 H+[e] + Ala-His[e] <=> H+[c] + Ala-His[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4427 H+[e] + N(alpha)-acetyl-L-methionine[e] <=> H+[c] + N(alpha)-acetyl-L-methionine[c] 0.00 1000.00 0.00 +r_4428 H+[e] + O(4)-phospho-L-tyrosine[e] <=> H+[c] + O(4)-phospho-L-tyrosine[c] 0.00 1000.00 0.00 +r_4429 H+[e] + Ala-His[e] <=> H+[c] + Ala-His[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4430 H+[c] + Ala-His[c] <=> H+[v] + Ala-His[v] -1000.00 1000.00 0.00 r_4431 H+[c] + Ala-Asp[c] <=> H+[v] + Ala-Asp[v] -1000.00 1000.00 0.00 r_4432 FMNH2[c] + oxygen[c] + 2-hydroxyethane-1-sulfonate[c] => FMN[c] + glycolaldehyde[c] + 2 H+[c] + H2O[c] + sulphite[c] 0.00 1000.00 0.00 @@ -3791,50 +3765,50 @@ r_4433 thymidine 3'-monophosphate[e] <=> thymidine 3'-monophosphate[c] -1000.0 r_4434 thymidine 5'-monophosphate[e] <=> thymidine 5'-monophosphate[c] -1000.00 1000.00 0.00 r_4435 H2O[c] + glycerol 1-phosphate[c] => glycerol[c] + phosphate[c] YIL053W or YER062C 0.00 1000.00 0.00 r_4436 H2O[c] + thymidine 5'-monophosphate[c] => phosphate[c] + thymidine[c] 0.00 1000.00 0.00 -r_4437 H+[e] + Gly-Glu[e] <=> H+[c] + Gly-Glu[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4437 H+[e] + Gly-Glu[e] <=> H+[c] + Gly-Glu[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4438 H+[c] + Gly-Glu[c] <=> H+[v] + Gly-Glu[v] -1000.00 1000.00 0.00 r_4439 H2O[v] + Gly-Glu[v] => L-glutamate[v] + L-glycine[v] 0.00 1000.00 0.00 r_4440 L-methionine[c] <=> L-methionine[v] -1000.00 1000.00 0.00 r_4441 L-threonine[c] <=> L-threonine[v] -1000.00 1000.00 0.00 r_4442 cysteamine[e] => 0.00 1000.00 0.00 r_4443 2',3'-cyclic GMP[e] <=> 2',3'-cyclic GMP[c] -1000.00 1000.00 0.00 -r_4444 H+[e] + 2-phospho-D-glyceric acid[e] <=> 2-phospho-D-glyceric acid[c] + H+[c] -1000.00 1000.00 0.00 -r_4445 H+[e] + 3-phosphonato-D-glycerate(3-)[e] <=> 3-phosphonato-D-glycerate(3-)[c] + H+[c] -1000.00 1000.00 0.00 +r_4444 H+[e] + 2-phospho-D-glyceric acid[e] <=> 2-phospho-D-glyceric acid[c] + H+[c] 0.00 1000.00 0.00 +r_4445 H+[e] + 3-phosphonato-D-glycerate(3-)[e] <=> 3-phosphonato-D-glycerate(3-)[c] + H+[c] 0.00 1000.00 0.00 r_4446 D-glucose 1-phosphate[e] <=> D-glucose 1-phosphate[c] -1000.00 1000.00 0.00 r_4447 carbamoyl phosphate[e] <=> carbamoyl phosphate[c] -1000.00 1000.00 0.00 -r_4448 H+[e] + Met-Ala[e] <=> H+[c] + Met-Ala[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4448 H+[e] + Met-Ala[e] <=> H+[c] + Met-Ala[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4449 H+[c] + Met-Ala[c] <=> H+[v] + Met-Ala[v] -1000.00 1000.00 0.00 -r_4450 H+[e] + 3-phospho-serine[e] <=> 3-phospho-serine[c] + H+[c] -1000.00 1000.00 0.00 -r_4451 H+[e] + GMP[e] <=> GMP[c] + H+[c] -1000.00 1000.00 0.00 +r_4450 H+[e] + 3-phospho-serine[e] <=> 3-phospho-serine[c] + H+[c] 0.00 1000.00 0.00 +r_4451 H+[e] + GMP[e] <=> GMP[c] + H+[c] 0.00 1000.00 0.00 r_4452 myo-inositol hexakisphosphate[e] <=> myo-inositol hexakisphosphate[c] -1000.00 1000.00 0.00 r_4453 D-glucose 6-phosphate[e] <=> D-glucose 6-phosphate[c] -1000.00 1000.00 0.00 r_4454 UMP[e] <=> UMP[c] -1000.00 1000.00 0.00 -r_4455 H+[e] + phosphoenolpyruvate[e] <=> H+[c] + phosphoenolpyruvate[c] -1000.00 1000.00 0.00 +r_4455 H+[e] + phosphoenolpyruvate[e] <=> H+[c] + phosphoenolpyruvate[c] 0.00 1000.00 0.00 r_4456 D-mannose 6-phosphate[e] <=> D-mannose 6-phosphate[c] -1000.00 1000.00 0.00 -r_4457 H+[e] + O-phosphoethanolamine[e] <=> H+[c] + O-phosphoethanolamine[c] YDR093W -1000.00 1000.00 0.00 -r_4458 H+[e] + 6-phospho-D-gluconate[e] <=> 6-phospho-D-gluconate[c] + H+[c] -1000.00 1000.00 0.00 -r_4459 H+[e] + D-mannose 1-phosphate[e] <=> D-mannose 1-phosphate[c] + H+[c] -1000.00 1000.00 0.00 -r_4460 2 H+[e] + diphosphate[e] <=> diphosphate[c] + 2 H+[c] -1000.00 1000.00 0.00 +r_4457 H+[e] + O-phosphoethanolamine[e] <=> H+[c] + O-phosphoethanolamine[c] YDR093W 0.00 1000.00 0.00 +r_4458 H+[e] + 6-phospho-D-gluconate[e] <=> 6-phospho-D-gluconate[c] + H+[c] 0.00 1000.00 0.00 +r_4459 H+[e] + D-mannose 1-phosphate[e] <=> D-mannose 1-phosphate[c] + H+[c] 0.00 1000.00 0.00 +r_4460 2 H+[e] + diphosphate[e] <=> diphosphate[c] + 2 H+[c] 0.00 1000.00 0.00 r_4461 choline phosphate[e] <=> choline phosphate[c] -1000.00 1000.00 0.00 r_4462 thiosulfate[e] <=> thiosulfate[c] -1000.00 1000.00 0.00 -r_4463 H+[e] + AMP[e] <=> AMP[c] + H+[c] -1000.00 1000.00 0.00 +r_4463 H+[e] + AMP[e] <=> AMP[c] + H+[c] 0.00 1000.00 0.00 r_4464 2',3'-cyclic AMP[e] <=> 2',3'-cyclic AMP[c] -1000.00 1000.00 0.00 -r_4465 H+[e] + adenosine 2'-phosphate[e] <=> adenosine 2'-phosphate[c] + H+[c] -1000.00 1000.00 0.00 -r_4466 H+[e] + CMP[e] <=> CMP[c] + H+[c] -1000.00 1000.00 0.00 +r_4465 H+[e] + adenosine 2'-phosphate[e] <=> adenosine 2'-phosphate[c] + H+[c] 0.00 1000.00 0.00 +r_4466 H+[e] + CMP[e] <=> CMP[c] + H+[c] 0.00 1000.00 0.00 r_4467 D-Glucosamine[e] <=> D-Glucosamine[c] -1000.00 1000.00 0.00 r_4468 2-deoxy-D-ribose[e] <=> 2-deoxy-D-ribose[c] YDR342C or YHR092C -1000.00 1000.00 0.00 -r_4469 H+[e] + L-citrulline[e] <=> H+[c] + L-citrulline[c] YKR039W -1000.00 1000.00 0.00 +r_4469 H+[e] + L-citrulline[e] <=> H+[c] + L-citrulline[c] YKR039W 0.00 1000.00 0.00 r_4470 glycerone[e] <=> glycerone[c] -1000.00 1000.00 0.00 -r_4471 H+[e] + Ala-Leu[e] <=> H+[c] + Ala-Leu[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4471 H+[e] + Ala-Leu[e] <=> H+[c] + Ala-Leu[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4472 H+[c] + Ala-Leu[c] <=> H+[v] + Ala-Leu[v] -1000.00 1000.00 0.00 -r_4473 H+[e] + Ala-Gly[e] <=> H+[c] + Ala-Gly[c] YJR152W or YKR093W -1000.00 1000.00 0.00 +r_4473 H+[e] + Ala-Gly[e] <=> H+[c] + Ala-Gly[c] YJR152W or YKR093W 0.00 1000.00 0.00 r_4474 H+[c] + Ala-Gly[c] <=> H+[v] + Ala-Gly[v] -1000.00 1000.00 0.00 r_4475 N-acetyl-L-glutamate[e] <=> N-acetyl-L-glutamate[c] -1000.00 1000.00 0.00 r_4476 N-acetyl-L-glutamate[c] <=> N-acetyl-L-glutamate[m] -1000.00 1000.00 0.00 -r_4477 H+[e] + lipoamide[e] <=> H+[c] + lipoamide[c] -1000.00 1000.00 0.00 +r_4477 H+[e] + lipoamide[e] <=> H+[c] + lipoamide[c] 0.00 1000.00 0.00 r_4478 L-Methionine S-oxide[e] <=> L-Methionine S-oxide[c] -1000.00 1000.00 0.00 r_4479 H+[c] + Gly-Asn[c] <=> H+[v] + Gly-Asn[v] -1000.00 1000.00 0.00 -r_4480 H+[e] + cysteamine[e] <=> H+[c] + cysteamine[c] -1000.00 1000.00 0.00 +r_4480 H+[e] + cysteamine[e] <=> H+[c] + cysteamine[c] 0.00 1000.00 0.00 r_4481 hydrogen sulfide[c] + 2 oxygen[c] => H+[c] + sulphate[c] 0.00 1000.00 0.00 r_4482 H+[c] + L-alanine[c] <=> H+[v] + L-alanine[v] -1000.00 1000.00 0.00 r_4483 H+[c] + L-glycine[c] <=> H+[v] + L-glycine[v] -1000.00 1000.00 0.00 @@ -3921,7 +3895,6 @@ r_4563 3'-UMP[e] => 0.00 1000.00 0.00 r_4564 2',3'-cyclic CMP[e] => 0.00 1000.00 0.00 r_4565 2',3'-cyclic UMP[e] => 0.00 1000.00 0.00 r_4567 6-phospho-D-gluconate[c] + H2O[c] => phosphate[c] + D-gluconate[c] 0.00 1000.00 0.00 -r_4568 H+[c] + phenylacetic acid[c] => 4-hydroxyphenyl acetate[c] 0.00 1000.00 0.00 r_4569 acetate[c] + H+[c] + Hydroquinone[c] => H2O[c] + 4-hydroxyphenyl acetate[c] 0.00 1000.00 0.00 r_4570 NAD[c] + 2-hydroxyglutarate[c] <=> 2-oxoglutarate[c] + H+[c] + NADH[c] YIL074C or YER081W -1000.00 1000.00 0.00 r_4571 coenzyme A[c] + H+[c] + 2-hydroxyglutarate[c] <=> glyoxylate[c] + H2O[c] + propionyl-CoA[c] -1000.00 1000.00 0.00 @@ -3935,19 +3908,19 @@ r_4583 H2O[c] + trans-2,cis-9-octadecadienoyl-CoA[c] => coenzyme A[c] + H+[c] + r_4584 ATP[c] + coenzyme A[c] + (9Z,12Z)-octadecadienoate[c] => AMP[c] + diphosphate[c] + trans-2,cis-9-octadecadienoyl-CoA[c] YOR317W or YER015W or YMR246W or YIL009W 0.00 1000.00 0.00 r_4585 H2O[c] + stachyose[c] => D-galactose[c] + raffinose[c] 0.00 1000.00 0.00 r_4586 sucrose[c] + stachyose[c] => 2 raffinose[c] 0.00 1000.00 0.00 -r_4587 H+[e] + Ca(2+)[e] <=> H+[c] + Ca(2+)[c] YOL122C -1000.00 1000.00 0.00 +r_4587 H+[e] + Ca(2+)[e] <=> H+[c] + Ca(2+)[c] YOL122C 0.00 1000.00 0.00 r_4588 chloride[e] <=> chloride[c] YNL275W -1000.00 1000.00 0.00 -r_4589 H+[e] + Cu2(+)[e] <=> H+[c] + Cu2(+)[c] YOL122C -1000.00 1000.00 0.00 -r_4590 H+[e] + Mn(2+)[e] <=> H+[c] + Mn(2+)[c] YOL130W -1000.00 1000.00 0.00 -r_4591 H+[e] + Zn(2+)[e] <=> H+[c] + Zn(2+)[c] YGL255W or YLR130C -1000.00 1000.00 0.00 -r_4592 H+[e] + Mg(2+)[e] <=> H+[c] + Mg(2+)[c] YGR191W or YOL130W -1000.00 1000.00 0.00 +r_4589 H+[e] + Cu2(+)[e] <=> H+[c] + Cu2(+)[c] YOL122C 0.00 1000.00 0.00 +r_4590 H+[e] + Mn(2+)[e] <=> H+[c] + Mn(2+)[c] YOL130W 0.00 1000.00 0.00 +r_4591 H+[e] + Zn(2+)[e] <=> H+[c] + Zn(2+)[c] YGL255W or YLR130C 0.00 1000.00 0.00 +r_4592 H+[e] + Mg(2+)[e] <=> H+[c] + Mg(2+)[c] YGR191W or YOL130W 0.00 1000.00 0.00 r_4593 chloride[e] <=> -1000.00 1000.00 0.00 r_4594 Cu2(+)[e] <=> -1000.00 1000.00 0.00 r_4595 Mn(2+)[e] <=> -1000.00 1000.00 0.00 r_4596 Zn(2+)[e] <=> -1000.00 1000.00 0.00 r_4597 Mg(2+)[e] <=> -1000.00 1000.00 0.00 -r_4598 0.00019 coenzyme A[c] + 1e-05 FAD[c] + 1e-06 glutathione[c] + 0.00265 NAD[c] + 0.00015 NADH[c] + 0.00057 NADP(+)[c] + 0.0027 NADPH[c] + 0.00099 riboflavin[c] + 1.2e-06 TDP[c] + 6.34e-05 THF[c] + 1e-06 heme a[c] => cofactor[c] 0.00 1000.00 0.00 -r_4599 3.04e-05 iron(2+)[c] + 0.00363 potassium[c] + 0.00397 sodium[c] + 0.02 sulphate[c] + 0.00129 chloride[c] + 0.00273 Mn(2+)[c] + 0.000748 Zn(2+)[c] + 0.000217 Ca(2+)[c] + 0.0012425 Mg(2+)[c] + 0.000659 Cu2(+)[c] => ion[c] 0.00 1000.00 0.00 +r_4598 0.00019 coenzyme A[c] + 1e-05 FAD[c] + 1e-06 glutathione[c] + 0.017373 H+[c] + 0.00265 NAD[c] + 0.00015 NADH[c] + 0.00057 NADP(+)[c] + 0.0027 NADPH[c] + 0.00099 riboflavin[c] + 1.2e-06 TDP[c] + 6.34e-05 THF[c] + 1e-06 heme a[c] => cofactor[c] 0.00 1000.00 0.00 +r_4599 0.022436 H+[c] + 3.04e-05 iron(2+)[c] + 0.00363 potassium[c] + 0.00397 sodium[c] + 0.02 sulphate[c] + 0.00129 chloride[c] + 0.00273 Mn(2+)[c] + 0.000748 Zn(2+)[c] + 0.000217 Ca(2+)[c] + 0.0012425 Mg(2+)[c] + 0.000659 Cu2(+)[c] => ion[c] 0.00 1000.00 0.00 r_4600 Ca(2+)[e] <=> -1000.00 1000.00 0.00 r_4601 3-(4-hydroxyphenyl)pyruvate[c] + H+[c] <=> 3-(4-hydroxyphenyl)pyruvate[p] + H+[p] -1000.00 1000.00 0.00 r_4602 acetate[c] <=> acetate[er] -1000.00 1000.00 0.00 @@ -3977,7 +3950,7 @@ r_4625 thiosulfate[c] <=> thiosulfate[m] -1000.00 1000.00 0.00 r_4626 sulphite[c] <=> sulphite[m] -1000.00 1000.00 0.00 r_4627 UDP-D-glucose[c] <=> UDP-D-glucose[er] -1000.00 1000.00 0.00 r_4628 UDP-N-acetyl-alpha-D-glucosamine[c] <=> UDP-N-acetyl-alpha-D-glucosamine[g] -1000.00 1000.00 0.00 -r_4629 ethanol[m] + hexanoyl-CoA[m] <=> coenzyme A[m] + ethyl hexanoate[m] YBR177C or YPL095C -1000.00 1000.00 0.00 +r_4629 ethanol[m] + hexanoyl-CoA[m] <=> coenzyme A[m] + 4 H+[m] + ethyl hexanoate[m] YBR177C or YPL095C -1000.00 1000.00 0.00 r_4630 ethanol[m] + octanoyl-CoA[m] <=> coenzyme A[m] + ethyl octanoate[m] YBR177C or YPL095C -1000.00 1000.00 0.00 r_4631 ethanol[m] + butanoyl-CoA[m] <=> coenzyme A[m] + ethyl butanoate[m] YBR177C or YPL095C -1000.00 1000.00 0.00 r_4632 acetyl-CoA[m] + hexanol[m] <=> coenzyme A[m] + hexyl acetate[m] YGR177C or YOR377W or YGR015C -1000.00 1000.00 0.00 @@ -4027,7 +4000,7 @@ r_4675 tyrosol[c] <=> tyrosol[e] -1000.00 1000.00 0.00 r_4676 (4-hydroxyphenyl)acetaldehyde[e] => 0.00 1000.00 0.00 r_4677 tyrosol[e] => 0.00 1000.00 0.00 r_4678 H2O[c] + NAD[c] + propanal[c] <=> H+[c] + NADH[c] + propionate[c] YMR170C or YMR169C or YOR374W -1000.00 1000.00 0.00 -r_4679 ATP[p] + coenzyme A[p] + propionate[p] <=> AMP[p] + diphosphate[p] + propionyl-CoA[p] YOR317W or YER015W or YIL009W or YMR246W -1000.00 1000.00 0.00 +r_4679 ATP[p] + coenzyme A[p] + propionate[p] <=> AMP[p] + diphosphate[p] + H+[p] + propionyl-CoA[p] YOR317W or YER015W or YIL009W or YMR246W -1000.00 1000.00 0.00 r_4680 ethanol[m] + propionyl-CoA[m] <=> coenzyme A[m] + ethyl propionate[m] YBR177C or YPL095C -1000.00 1000.00 0.00 r_4681 propionyl-CoA[p] <=> propionyl-CoA[m] -1000.00 1000.00 0.00 r_4682 butanoyl-CoA[p] <=> butanoyl-CoA[m] -1000.00 1000.00 0.00 @@ -4048,20 +4021,17 @@ r_4697 ethyl propionate[m] <=> ethyl propionate[c] -1000.00 1000.00 0.00 r_4698 ethyl propionate[c] => ethyl propionate[e] YNL065W or YKL217W 0.00 1000.00 0.00 r_4699 ethyl propionate[e] => 0.00 1000.00 0.00 r_4700 hydrogen sulfide[c] => hydrogen sulfide[e] YIL166C 0.00 1000.00 0.00 -r_4701 H2O[m] + L-cysteine[m] <=> ammonium[m] + pyruvate[m] + hydrogen sulfide[m] YFR055W -1000.00 1000.00 0.00 -r_4702 2-oxoglutarate[c] + L-cysteine[c] <=> L-glutamate[c] + 3-mercaptopyruvate[c] -1000.00 1000.00 0.00 -r_4703 TRX1[c] + 3-mercaptopyruvate[c] => hydrogen sulfide[c] + pyruvate[c] + TRX1 disulphide[c] YOR251C 0.00 1000.00 0.00 -r_4704 alkanesulfonate[e] => alkanesulfonate[c] YIL166C 0.00 1000.00 0.00 +r_4701 H2O[m] + L-cysteine[m] <=> ammonium[m] + H+[m] + pyruvate[m] + hydrogen sulfide[m] YFR055W -1000.00 1000.00 0.00 +r_4702 2-oxoglutarate[c] + H+[c] + L-cysteine[c] <=> L-glutamate[c] + 3-mercaptopyruvate[c] -1000.00 1000.00 0.00 +r_4703 TRX1[c] + 3-mercaptopyruvate[c] => H+[c] + hydrogen sulfide[c] + pyruvate[c] + TRX1 disulphide[c] YOR251C 0.00 1000.00 0.00 r_4705 taurocholate[e] => taurocholate[c] YIL166C 0.00 1000.00 0.00 -r_4706 2-oxoglutarate[c] + oxygen[c] + alkanesulfonate[c] <=> aminoacetaldehyde[c] + carbon dioxide[c] + succinate[c] + sulphite[c] YLL057C -1000.00 1000.00 0.00 -r_4707 H2O[c] + trithionate[c] <=> sulphate[c] + thiosulfate[c] -1000.00 1000.00 0.00 +r_4707 H2O[c] + trithionate[c] <=> H+[c] + sulphate[c] + thiosulfate[c] -1000.00 1000.00 0.00 r_4708 hydrogen sulfide[e] => 0.00 1000.00 0.00 -r_4709 alkanesulfonate[e] => 0.00 1000.00 0.00 r_4710 taurocholate[e] => 0.00 1000.00 0.00 r_4711 (S)-lactate[c] + ethanol[c] + H+[c] <=> H2O[c] + ethyl (2S)-lactate[c] YOR126C -1000.00 1000.00 0.00 r_4712 (R)-lactate[c] + ethanol[c] + H+[c] <=> H2O[c] + ethyl (2R)-lactate[c] YOR126C -1000.00 1000.00 0.00 -r_4713 2 ethanol[c] + 2 H+[c] + succinate[c] <=> 2 H2O[c] + diethyl succinate[c] YOR126C -1000.00 1000.00 0.00 -r_4714 ethanol[c] + H+[c] + succinate[c] <=> H2O[c] + monoethyl succinate[c] YOR126C -1000.00 1000.00 0.00 +r_4713 2 ethanol[c] + 2 H+[c] + succinate[c] <=> 2 H2O[c] + diethyl succinate[c] YOR126C -1000.00 0.00 0.00 +r_4714 ethanol[c] + H+[c] + succinate[c] <=> H2O[c] + monoethyl succinate[c] YOR126C -1000.00 0.00 0.00 r_4715 ethanol[c] + H+[c] + Benzoate[c] <=> H2O[c] + ethyl benzoate[c] YOR126C -1000.00 1000.00 0.00 r_4716 ethanol[c] + H+[c] + pyruvate[c] <=> H2O[c] + ethyl pyruvate[c] YOR126C -1000.00 1000.00 0.00 r_4717 acetate[c] + H+[c] + benzyl alcohol[c] <=> H2O[c] + benzyl acetate[c] YOR126C -1000.00 1000.00 0.00 @@ -4070,9 +4040,9 @@ r_4719 2-methylbutanal[c] + H2O[c] + NAD[c] <=> 2 H+[c] + NADH[c] + 2-methylbuty r_4720 ethanol[c] + H+[c] + isobutyrate[c] <=> H2O[c] + ethyl isobutyrate[c] YOR126C -1000.00 1000.00 0.00 r_4721 ethanol[c] + H+[c] + 2-methylbutyrate[c] <=> H2O[c] + ethyl 2-methylbutyrate[c] YOR126C -1000.00 1000.00 0.00 r_4722 2 ATP[c] + H2O[c] => 2 ADP[c] + H+[c] + polyphosphate[v] YJL012C 0.00 1000.00 0.00 -r_4723 H2O[v] + polyphosphate[v] <=> H+[v] + 2 phosphate[v] YHR201C or YDR452W -1000.00 1000.00 0.00 -r_4724 H2O[m] + polyphosphate[m] <=> H+[m] + 2 phosphate[m] YHR201C or YDR452W -1000.00 1000.00 0.00 -r_4725 H2O[n] + polyphosphate[n] <=> H+[n] + 2 phosphate[n] YHR201C or YDR452W -1000.00 1000.00 0.00 +r_4723 H2O[v] + polyphosphate[v] <=> H+[v] + 2 phosphate[v] YHR201C or YDR452W 0.00 1000.00 0.00 +r_4724 H2O[m] + polyphosphate[m] <=> H+[m] + 2 phosphate[m] YHR201C or YDR452W 0.00 1000.00 0.00 +r_4725 H2O[n] + polyphosphate[n] <=> H+[n] + 2 phosphate[n] YHR201C or YDR452W 0.00 1000.00 0.00 r_4726 ethyl (2S)-lactate[c] <=> ethyl (2S)-lactate[e] -1000.00 1000.00 0.00 r_4727 ethyl (2S)-lactate[e] => 0.00 1000.00 0.00 r_4728 ethyl (2R)-lactate[c] <=> ethyl (2R)-lactate[e] -1000.00 1000.00 0.00 @@ -4106,7 +4076,6 @@ r_4755 pyruvate[m] + 2-hydroxyglutarate[m] => (R)-lactate[m] + 2-oxoglutarate[m] r_4756 cytidine[c] + H2O[c] => cytosine[c] + D-ribose[c] YDR400W 0.00 1000.00 0.00 r_4757 ATP[c] + D-ribulose[c] <=> ADP[c] + D-ribulose 5-phosphate[c] + H+[c] YDR109C -1000.00 1000.00 0.00 r_4758 2'-deoxyguanosine[c] + phosphate[c] <=> guanine[c] + 2-deoxy-D-ribose 1-phosphate[c] YLR209C -1000.00 1000.00 0.00 -r_4759 H2O[p] + deamido-NAD(+)[p] => AMP[p] + 2 H+[p] + nicotinic acid D-ribonucleotide[p] YGL067W 0.00 1000.00 0.00 r_4760 NAD[c] + trans-4-hydroxy-L-proline[c] <=> 1-pyrroline-3-hydroxy-5-carboxylic acid[c] + 2 H+[c] + NADH[c] YER023W -1000.00 1000.00 0.00 r_4761 2-oxoglutarate[c] + 3-hydroxy-L-kynurenine[c] => H2O[c] + L-glutamate[c] + xanthurenate[c] YJL060W 0.00 1000.00 0.00 r_4762 H2O[m] + 3-hydroxyisobutyryl-CoA[m] <=> coenzyme A[m] + H+[m] + 3-hydroxyisobutyrate[m] YDR036C -1000.00 1000.00 0.00 @@ -4130,3 +4099,5 @@ r_4779 heme a[c] <=> heme a[e] -1000.00 1000.00 0.00 r_4780 heme a[e] => 0.00 1000.00 0.00 r_4781 H2O[c] + ADP-5-ethyl-4-methylthiazole-2-carboxylate[c] => 4-methyl-5-(2-phosphonooxyethyl)thiazole[c] + AMP[c] + carbon dioxide[c] + H+[c] YGR144W 0.00 1000.00 0.00 r_4782 hydrogen sulfide[c] + L-glycine[c] + NAD[c] => H+[c] + 3 H2O[c] + nicotinamide[c] + ADP-5-ethyl-4-methylthiazole-2-carboxylate[c] YGR144W 0.00 1000.00 0.00 +r_4783 oxaloacetate[c] + sulphate[m] <=> oxaloacetate[m] + sulphate[c] YKL120W -1000.00 1000.00 0.00 +r_4784 (S)-malate[c] + sulphate[m] <=> (S)-malate[m] + sulphate[c] YKL120W -1000.00 1000.00 0.00 diff --git a/model/yeast-GEM.xml b/model/yeast-GEM.xml index c664e445..e154fd0c 100644 --- a/model/yeast-GEM.xml +++ b/model/yeast-GEM.xml @@ -24,10 +24,10 @@ - 2024-11-23T16:03:25Z + 2026-05-27T23:08:53Z - 2024-11-23T16:03:25Z + 2026-05-27T23:08:53Z @@ -1081,7 +1081,7 @@ - + @@ -7559,7 +7559,7 @@ - + @@ -10194,7 +10194,7 @@ - + @@ -10883,7 +10883,7 @@ - + @@ -13867,7 +13867,7 @@ - + @@ -16397,7 +16397,7 @@ - + @@ -16587,7 +16587,7 @@ - + @@ -16603,7 +16603,7 @@ - + @@ -17497,7 +17497,7 @@ - + @@ -17513,7 +17513,7 @@ - + @@ -19917,7 +19917,7 @@ - + @@ -21756,22 +21756,6 @@ - - - - - - - - - - - - - - - - @@ -32612,7 +32596,7 @@ - + @@ -32705,7 +32689,7 @@ - + @@ -32720,7 +32704,7 @@ - + @@ -32734,7 +32718,7 @@ - + @@ -32747,7 +32731,7 @@ - + @@ -32760,7 +32744,7 @@ - + @@ -32771,7 +32755,7 @@ - + @@ -32782,7 +32766,7 @@ - + @@ -32793,7 +32777,7 @@ - + @@ -32804,7 +32788,7 @@ - + @@ -32815,7 +32799,7 @@ - + @@ -32826,7 +32810,7 @@ - + @@ -32837,7 +32821,7 @@ - + @@ -32848,7 +32832,7 @@ - + @@ -32859,7 +32843,7 @@ - + @@ -32870,7 +32854,7 @@ - + @@ -32881,7 +32865,7 @@ - + @@ -32892,7 +32876,7 @@ - + @@ -32903,7 +32887,7 @@ - + @@ -32914,7 +32898,7 @@ - + @@ -32925,7 +32909,7 @@ - + @@ -32936,7 +32920,7 @@ - + @@ -32947,7 +32931,7 @@ - + @@ -32958,7 +32942,7 @@ - + @@ -32969,7 +32953,7 @@ - + @@ -32980,7 +32964,7 @@ - + @@ -32991,7 +32975,7 @@ - + @@ -33002,7 +32986,7 @@ - + @@ -33013,7 +32997,7 @@ - + @@ -33024,7 +33008,7 @@ - + @@ -33035,7 +33019,7 @@ - + @@ -33046,7 +33030,7 @@ - + @@ -33608,17 +33592,6 @@ - - - - - - - - - - - @@ -33635,17 +33608,6 @@ - - - - - - - - - - - @@ -34104,50 +34066,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -34180,7 +34098,7 @@ - + @@ -34196,7 +34114,7 @@ - + @@ -34239,21 +34157,6 @@ - - - - - - - - - - - - - - - @@ -34270,81 +34173,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -34422,21 +34250,6 @@ - - - - - - - - - - - - - - - @@ -34453,36 +34266,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -34593,36 +34376,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -34771,36 +34524,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -34912,36 +34635,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -35036,34 +34729,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -35240,47 +34905,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -35327,7 +34951,7 @@ - + @@ -35344,53 +34968,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -35466,68 +35043,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -35586,36 +35101,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -35737,84 +35222,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -35843,67 +35250,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -36437,34 +35783,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -36706,70 +36024,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -37066,51 +36320,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -37127,34 +36336,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -39765,7 +38946,7 @@ - + @@ -39776,7 +38957,7 @@ - + @@ -39802,29 +38983,39 @@ - + - - + + - + + + + + + - + - - + + - + + + + + + - + @@ -40496,7 +39687,7 @@ - + @@ -40530,38 +39721,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -41325,44 +40484,6 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -41605,6 +40726,36 @@ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -41963,12 +41114,13 @@ - + + - + @@ -49271,7 +48423,7 @@ - +

Confidence Level: 3

@@ -49325,7 +48477,7 @@ - +

Confidence Level: 3

@@ -50020,10 +49172,11 @@
- +

Confidence Level: 3

+

NOTES: Only active if growth medium contains carnitine

@@ -54451,7 +53604,7 @@
- +

Confidence Level: 3

@@ -55358,10 +54511,11 @@
- +

Confidence Level: 3

+

NOTES: Only active during nitrogen restriction

@@ -55929,13 +55083,13 @@ - - - - + + + + @@ -56224,10 +55378,11 @@
- +

Confidence Level: 2

+

NOTES: Only active if glycine is nitrogen source, or under nitrogen restriction

@@ -56523,11 +55678,11 @@
- +

Confidence Level: 2

-

NOTES: MetaNetX ID curated (PR #220) | KEGG ID curated (PR #220) | model.S(606,396) curated (PR #222)

+

NOTES: Only active if glycine is nitrogen source, or under nitrogen restriction

@@ -56627,10 +55782,11 @@
- +

Confidence Level: 2

+

NOTES: Only active if glycine is nitrogen source, or under nitrogen restriction

@@ -63059,6 +62215,7 @@ + @@ -63436,7 +62593,7 @@
- +

Confidence Level: 2

@@ -63460,18 +62617,18 @@ - - - - + + + +
- +

Confidence Level: 3

@@ -63498,12 +62655,12 @@ - - - - + + + + @@ -64818,7 +63975,7 @@ - + @@ -64855,7 +64012,7 @@ - + @@ -65801,7 +64958,7 @@ - +
@@ -67049,51 +66206,6 @@ - - - -

Confidence Level: 2

- -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
@@ -68336,13 +67448,13 @@ - + - + @@ -73566,7 +72678,7 @@ - +

Confidence Level: 3

@@ -74487,7 +73599,7 @@
- +

Confidence Level: 2

@@ -75223,7 +74335,7 @@
- +

Confidence Level: 2

@@ -75432,7 +74544,7 @@
- +

Confidence Level: 3

@@ -75469,7 +74581,7 @@
- +

Confidence Level: 2

@@ -75537,7 +74649,7 @@
- +

Confidence Level: 3

@@ -75670,7 +74782,7 @@
- +

Confidence Level: 2

@@ -75732,7 +74844,7 @@
- +

Confidence Level: 3

@@ -75862,7 +74974,7 @@
- +

Confidence Level: 2

@@ -75963,7 +75075,7 @@
- +

Confidence Level: 2

@@ -76034,7 +75146,7 @@
- +

Confidence Level: 2

@@ -76163,7 +75275,7 @@
- +

Confidence Level: 2

@@ -76354,7 +75466,7 @@
- +

Confidence Level: 2

@@ -76427,7 +75539,7 @@
- +

Confidence Level: 2

@@ -76460,7 +75572,7 @@
- +

Confidence Level: 2

@@ -76498,7 +75610,7 @@
- +

Confidence Level: 2

@@ -76534,7 +75646,7 @@
- +

Confidence Level: 2

@@ -76567,7 +75679,7 @@
- +

Confidence Level: 2

@@ -76604,7 +75716,7 @@
- +

Confidence Level: 3

@@ -76639,7 +75751,7 @@
- +

Confidence Level: 3

@@ -76774,7 +75886,7 @@
- +

Confidence Level: 2

@@ -76811,7 +75923,7 @@
- +

Confidence Level: 2

@@ -77183,7 +76295,7 @@
- +

Confidence Level: 2

@@ -77243,7 +76355,7 @@
- +

Confidence Level: 2

@@ -77325,7 +76437,7 @@
- +

Confidence Level: 2

@@ -77394,7 +76506,7 @@
- +

Confidence Level: 3

@@ -77456,7 +76568,7 @@
- +

Confidence Level: 3

@@ -77523,7 +76635,7 @@
- +

Confidence Level: 3

@@ -77552,7 +76664,7 @@
- +

Confidence Level: 2

@@ -77732,7 +76844,7 @@
- +

Confidence Level: 3

@@ -77804,7 +76916,7 @@
- +

Confidence Level: 3

@@ -78145,7 +77257,7 @@
- +

Confidence Level: 2

@@ -80075,11 +79187,11 @@ + - @@ -89285,7 +88397,7 @@
- +

Confidence Level: 3

@@ -90618,7 +89730,6 @@ - @@ -90656,7 +89767,6 @@ - @@ -90695,7 +89805,6 @@ - @@ -93716,7 +92825,7 @@ - + @@ -93863,7 +92972,7 @@ - + @@ -94479,10 +93588,9 @@ - + - @@ -95452,6 +94560,7 @@ + @@ -97090,8 +96199,8 @@ - +
@@ -97161,8 +96270,8 @@ - +
@@ -97232,8 +96341,8 @@ - +
@@ -100873,7 +99982,7 @@ - +
@@ -100907,7 +100016,7 @@ - + @@ -100941,7 +100050,7 @@ - + @@ -100975,7 +100084,7 @@ - + @@ -101009,7 +100118,7 @@ - + @@ -146696,6 +145805,7 @@ + @@ -146720,6 +145830,7 @@ + @@ -146744,6 +145855,7 @@ + @@ -146768,6 +145880,7 @@ + @@ -148353,6 +147466,7 @@ + @@ -148363,7 +147477,8 @@ - + + @@ -148511,48 +147626,49 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
@@ -148602,6 +147718,7 @@ + @@ -148628,6 +147745,7 @@ + @@ -149250,6 +148368,7 @@ + @@ -149271,6 +148390,7 @@ + @@ -149298,6 +148418,7 @@ + @@ -149319,6 +148440,7 @@ + @@ -151820,38 +150942,6 @@
- - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - -
@@ -152480,43 +151570,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
@@ -152677,105 +151730,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142) | MetaNetX ID curated (PR #220)

- -
- - - - - - - - - - - - - - - - - - - - - - - - -
- - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142) | MetaNetX ID curated (PR #220)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142) | MetaNetX ID curated (PR #220)

- -
- - - - - - - - - - - - - - - - - - - - - - - - -
@@ -152938,38 +151892,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142) | MetaNetX ID curated (PR #220)

- -
- - - - - - - - - - - - - - - - - - - - - - - - -
@@ -153185,38 +152107,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - -
@@ -153518,42 +152408,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - -
@@ -153750,38 +152604,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - -
@@ -153926,39 +152748,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - -
@@ -154124,36 +152913,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - -
@@ -154286,72 +153045,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142) | model.S(606,3616) curated (PR #222)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - -
- - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142) | MetaNetX ID curated (PR #220)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - -
@@ -154455,73 +153148,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - -
- - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - - -
@@ -154674,39 +153300,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - -
@@ -155091,76 +153684,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - - - -
@@ -155194,70 +153717,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - -
- - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - -
@@ -156078,39 +154537,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - -
@@ -156561,111 +154987,12 @@ - - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - -
@@ -157116,38 +155443,6 @@ - - - -

Confidence Level: 2

-

NOTES: added after new annotation (PR #142)

- -
- - - - - - - - - - - - - - - - - - - - - - - - -
@@ -157203,7 +155498,7 @@ - +

Confidence Level: 1

@@ -157286,7 +155581,7 @@
- +

Confidence Level: 1

@@ -157341,7 +155636,7 @@
- +

Confidence Level: 1

@@ -157368,7 +155663,7 @@
- +

Confidence Level: 1

@@ -157567,7 +155862,7 @@
- +

Confidence Level: 1

@@ -157620,7 +155915,7 @@
- +

Confidence Level: 1

@@ -157677,7 +155972,7 @@
- +

Confidence Level: 1

@@ -157705,7 +156000,7 @@
- +

Confidence Level: 2

@@ -157793,7 +156088,7 @@
- +

Confidence Level: 1

@@ -157818,7 +156113,7 @@
- +

Confidence Level: 1

@@ -157874,7 +156169,7 @@
- +

Confidence Level: 1

@@ -157929,7 +156224,7 @@
- +

Confidence Level: 1

@@ -157984,7 +156279,7 @@
- +

Confidence Level: 1

@@ -158042,7 +156337,7 @@
- +

Confidence Level: 1

@@ -158099,7 +156394,7 @@
- +

Confidence Level: 1

@@ -158209,7 +156504,7 @@
- +

Confidence Level: 1

@@ -158265,7 +156560,7 @@
- +

Confidence Level: 1

@@ -158378,7 +156673,7 @@
- +

Confidence Level: 1

@@ -158433,7 +156728,7 @@
- +

Confidence Level: 2

@@ -158497,7 +156792,7 @@
- +

Confidence Level: 1

@@ -158578,7 +156873,7 @@
- +

Confidence Level: 1

@@ -158764,7 +157059,7 @@
- +

Confidence Level: 2

@@ -158885,7 +157180,7 @@
- +

Confidence Level: 2

@@ -158951,7 +157246,7 @@
- +

Confidence Level: 2

@@ -159005,7 +157300,7 @@
- +

Confidence Level: 1

@@ -159063,7 +157358,7 @@
- +

Confidence Level: 2

@@ -159382,7 +157677,7 @@
- +

Confidence Level: 1

@@ -159443,7 +157738,7 @@
- +

Confidence Level: 1

@@ -159470,7 +157765,7 @@
- +

Confidence Level: 1

@@ -159524,7 +157819,7 @@
- +

Confidence Level: 2

@@ -159611,7 +157906,7 @@
- +

Confidence Level: 1

@@ -159638,7 +157933,7 @@
- +

Confidence Level: 1

@@ -159665,7 +157960,7 @@
- +

Confidence Level: 2

@@ -159890,7 +158185,7 @@
- +

Confidence Level: 2

@@ -160066,7 +158361,7 @@
- +

Confidence Level: 1

@@ -160094,7 +158389,7 @@
- +

Confidence Level: 1

@@ -160172,7 +158467,7 @@
- +

Confidence Level: 2

@@ -160228,7 +158523,7 @@
- +

Confidence Level: 1

@@ -160256,7 +158551,7 @@
- +

Confidence Level: 1

@@ -160359,7 +158654,7 @@
- +

Confidence Level: 1

@@ -160412,7 +158707,7 @@
- +

Confidence Level: 2

@@ -160442,7 +158737,7 @@
- +

Confidence Level: 1

@@ -160470,7 +158765,7 @@
- +

Confidence Level: 1

@@ -160498,7 +158793,7 @@
- +

Confidence Level: 1

@@ -160577,7 +158872,7 @@
- +

Confidence Level: 1

@@ -160630,7 +158925,7 @@
- +

Confidence Level: 1

@@ -160657,7 +158952,7 @@
- +

Confidence Level: 1

@@ -160742,7 +159037,7 @@
- +

Confidence Level: 2

@@ -160799,7 +159094,7 @@
- +

Confidence Level: 2

@@ -160855,7 +159150,7 @@
- +

Confidence Level: 2

@@ -160965,7 +159260,7 @@
- +

Confidence Level: 1

@@ -161043,7 +159338,7 @@
- +

Confidence Level: 1

@@ -162975,33 +161270,6 @@
- - - -

Confidence Level: 0

-

NOTES: metabolites observed in metabolomics data (PR #156) | MetaNetX ID curated (PR #220)

- -
- - - - - - - - - - - - - - - - - - - -
@@ -163414,7 +161682,7 @@ - +

Confidence Level: 2

@@ -163473,7 +161741,7 @@
- +

Confidence Level: 2

@@ -163503,7 +161771,7 @@
- +

Confidence Level: 2

@@ -163534,7 +161802,7 @@
- +

Confidence Level: 2

@@ -163568,7 +161836,7 @@
- +

Confidence Level: 2

@@ -163726,6 +161994,7 @@ + @@ -163756,6 +162025,7 @@ + @@ -164547,6 +162817,7 @@ + @@ -165943,6 +164214,7 @@ + @@ -166480,6 +164752,7 @@ + @@ -166509,6 +164782,7 @@ + @@ -166540,6 +164814,7 @@ + @@ -166548,32 +164823,6 @@
- - - -

AUTHORS: 10.1093/femsyr/foy046

-

NOTES: Sulfur volatiles curation (PR #296)

- -
- - - - - - - - - - - - - - - - - - -
@@ -166600,37 +164849,6 @@ - - - -

AUTHORS: 10.1093/femsyr/foy046

-

NOTES: Sulfur volatiles curation (PR #296)

- -
- - - - - - - - - - - - - - - - - - - - - - - -
@@ -166655,6 +164873,7 @@ + @@ -166679,26 +164898,6 @@ - - - -

AUTHORS: 10.1093/femsyr/foy046

-

NOTES: Sulfur volatiles curation (PR #296)

- -
- - - - - - - - - - - - -
@@ -166783,7 +164982,7 @@ - +

Confidence Level: 2

@@ -166815,7 +165014,7 @@
- +

Confidence Level: 2

@@ -167114,7 +165313,7 @@
- +

Confidence Level: 2

@@ -167151,7 +165350,7 @@
- +

Confidence Level: 2

@@ -167187,7 +165386,7 @@
- +

Confidence Level: 2

@@ -168103,39 +166302,6 @@
- - - -

NOTES: New rxns from databases curation (PR #304)

- -
- - - - - - - - - - - - - - - - - - - - - - - - - - -
@@ -168881,6 +167047,62 @@ + + + +

Confidence Level: 3

+

AUTHORS: 10.1074/jbc.274.32.22184

+ +
+ + + + + + + + + + + + + + + + + + + + +
+ + + +

Confidence Level: 3

+

AUTHORS: 10.1074/jbc.274.32.22184

+ +
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- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - @@ -187898,356 +186120,7 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - + @@ -188329,7 +186202,7 @@ - + @@ -188363,19 +186236,51 @@ - + - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - + @@ -188419,31 +186324,104 @@ - + - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - + - + + + + + + + + - + - - - - - + + + + + + + + + + + + + + + + + - + @@ -188455,170 +186433,143 @@ - + - - - - - - - - + + + + + + - + - + + + + + + + + + + + + - + - - - + + + + + + - + - - - - - - - - - - - - - - - - - - - - - + + - + - - - - - - - - - - + - + - - - - - - - - - - - - + + - + - - - - - - - - - - - - - - - - - - - - - - - + - + - - - - - - - - - - - - + - + - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/model/yeast-GEM.yml b/model/yeast-GEM.yml index fb81ec00..9cf3fcf4 100755 --- a/model/yeast-GEM.yml +++ b/model/yeast-GEM.yml @@ -4,7 +4,7 @@ id: "yeastGEM_develop" name: "The Consensus Genome-Scale Metabolic Model of Yeast" version: "" - date: "2024-11-23" + date: "2026-05-27" defaultLB: "-1000" defaultUB: "1000" givenName: "Eduard" @@ -906,7 +906,7 @@ - name: "1-phosphatidyl-1D-myo-inositol backbone" - compartment: "c" - formula: "C9H15O9P" - - charge: -1 + - charge: 0 - annotation: !!omap - bigg.metabolite: "pail_cho" - chebi: "CHEBI:57880" @@ -6525,6 +6525,7 @@ - name: "diglyceride backbone" - compartment: "er" - formula: "C3H4O" + - charge: 0 - annotation: !!omap - bigg.metabolite: "dag_hs" - chebi: "CHEBI:18035" @@ -8813,7 +8814,7 @@ - name: "hydrogen sulfide" - compartment: "c" - formula: "HS" - - charge: 0 + - charge: -1 - smiles: "S" - annotation: !!omap - bigg.metabolite: "h2s" @@ -9405,6 +9406,7 @@ - name: "inositol-P-ceramide backbone" - compartment: "g" - formula: "C6H12NO10P" + - charge: 0 - annotation: !!omap - chebi: "CHEBI:60245" - metanetx.chemical: "MNXM57446" @@ -11998,6 +12000,7 @@ - name: "mannosylinositol phosphorylceramide backbone" - compartment: "g" - formula: "C12H22NO15P" + - charge: 0 - annotation: !!omap - chebi: "CHEBI:25168" - metanetx.chemical: "MNXM12216" @@ -14192,7 +14195,7 @@ - name: "phosphatidylcholine backbone" - compartment: "c" - formula: "C8H16NO3P" - - charge: 1 + - charge: 0 - annotation: !!omap - bigg.metabolite: "pchol_cho" - chebi: "CHEBI:49183" @@ -14353,7 +14356,7 @@ - name: "potassium" - compartment: "c" - formula: "K" - - charge: 0 + - charge: 1 - smiles: "[K]" - annotation: !!omap - bigg.metabolite: "k" @@ -14367,7 +14370,7 @@ - name: "potassium" - compartment: "e" - formula: "K" - - charge: 0 + - charge: 1 - smiles: "[K]" - annotation: !!omap - bigg.metabolite: "k" @@ -15146,7 +15149,7 @@ - name: "sodium" - compartment: "c" - formula: "Na" - - charge: 0 + - charge: 1 - smiles: "[Na]" - annotation: !!omap - bigg.metabolite: "na1" @@ -15160,7 +15163,7 @@ - name: "sodium" - compartment: "e" - formula: "Na" - - charge: 0 + - charge: 1 - smiles: "[Na]" - annotation: !!omap - bigg.metabolite: "na1" @@ -17205,6 +17208,7 @@ - id: "s_1845" - name: "ACP1" - compartment: "m" + - formula: "RHS" - charge: 0 - annotation: !!omap - bigg.metabolite: "ACP" @@ -18791,20 +18795,6 @@ - metanetx.chemical: "MNXM553" - sbo: "SBO:0000247" - deltaG: -320.52 - - !!omap - - id: "s_2886" - - name: "but-2-enoyl-CoA" - - compartment: "p" - - formula: "C25H40N7O17P3S" - - charge: 0 - - smiles: "CC=CC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O" - - annotation: !!omap - - bigg.metabolite: "b2coa" - - chebi: "CHEBI:36926" - - kegg.compound: "C00877" - - metanetx.chemical: "MNXM214" - - sbo: "SBO:0000247" - - deltaG: -370.03 - !!omap - id: "s_2887" - name: "trans-hex-2-enoyl-CoA" @@ -27537,7 +27527,7 @@ - name: "phosphatidylcholine backbone" - compartment: "erm" - formula: "C8H16NO3P" - - charge: 1 + - charge: 0 - annotation: !!omap - bigg.metabolite: "pchol_cho" - kegg.compound: "C00157" @@ -27614,6 +27604,7 @@ - id: "s_3717" - name: "protein" - compartment: "c" + - charge: 0 - annotation: !!omap - bigg.metabolite: "protein" - kegg.compound: "C00492" @@ -27624,6 +27615,7 @@ - id: "s_3718" - name: "carbohydrate" - compartment: "c" + - charge: 0 - annotation: !!omap - kegg.compound: "C05402" - metanetx.chemical: "MNXM1434" @@ -27633,6 +27625,7 @@ - id: "s_3719" - name: "RNA" - compartment: "c" + - charge: 0 - annotation: !!omap - bigg.metabolite: "rna" - sbo: "SBO:0000649" @@ -27641,6 +27634,7 @@ - id: "s_3720" - name: "DNA" - compartment: "c" + - charge: 0 - annotation: !!omap - bigg.metabolite: "dna" - sbo: "SBO:0000649" @@ -27650,6 +27644,7 @@ - name: "ceramide backbone" - compartment: "g" - formula: "HNO2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27658,6 +27653,7 @@ - name: "ceramide backbone" - compartment: "c" - formula: "HNO2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27666,6 +27662,7 @@ - name: "inositol phosphomannosylinositol phosphoceramide backbone" - compartment: "c" - formula: "C18H33NO23P2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27674,6 +27671,7 @@ - name: "inositol-P-ceramide backbone" - compartment: "c" - formula: "C6H12NO10P" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27682,6 +27680,7 @@ - name: "mannosylinositol phosphorylceramide backbone" - compartment: "c" - formula: "C12H22NO15P" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27690,6 +27689,7 @@ - name: "long-chain base backbone" - compartment: "er" - formula: "H4N" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27698,6 +27698,7 @@ - name: "long-chain base backbone" - compartment: "c" - formula: "H4N" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27706,6 +27707,7 @@ - name: "long-chain base phosphate backbone" - compartment: "er" - formula: "H3NO3P" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27714,6 +27716,7 @@ - name: "long-chain base phosphate backbone" - compartment: "c" - formula: "H3NO3P" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27722,6 +27725,7 @@ - name: "phosphatidate backbone" - compartment: "erm" - formula: "C3H5O4P" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27730,6 +27734,7 @@ - name: "phosphatidate backbone" - compartment: "c" - formula: "C3H5O4P" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27738,6 +27743,7 @@ - name: "diglyceride backbone" - compartment: "erm" - formula: "C3H4O" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27746,6 +27752,7 @@ - name: "diglyceride backbone" - compartment: "c" - formula: "C3H4O" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27754,6 +27761,7 @@ - name: "sn-2-acyl-1-lysophosphatidylinositol backbone" - compartment: "erm" - formula: "C9H11O10P" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27762,6 +27770,7 @@ - name: "sn-2-acyl-1-lysophosphatidylinositol backbone" - compartment: "c" - formula: "C9H11O10P" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27770,6 +27779,7 @@ - name: "phosphatidylglycerol backbone" - compartment: "mm" - formula: "C6H11O6P" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27778,6 +27788,7 @@ - name: "phosphatidylglycerol backbone" - compartment: "c" - formula: "C6H11O6P" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27786,6 +27797,7 @@ - name: "cardiolipin backbone" - compartment: "mm" - formula: "C9H14O9P2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27794,6 +27806,7 @@ - name: "cardiolipin backbone" - compartment: "c" - formula: "C9H14O9P2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27802,6 +27815,7 @@ - name: "C16:0 chain" - compartment: "c" - formula: "C16H32O2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27810,6 +27824,7 @@ - name: "C16:1 chain" - compartment: "c" - formula: "C16H30O2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27818,6 +27833,7 @@ - name: "C18:0 chain" - compartment: "c" - formula: "C18H36O2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27826,6 +27842,7 @@ - name: "C18:1 chain" - compartment: "c" - formula: "C18H34O2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27834,6 +27851,7 @@ - name: "C24:0 chain" - compartment: "c" - formula: "C24H48O2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27842,6 +27860,7 @@ - name: "C26:0 chain" - compartment: "c" - formula: "C26H52O2" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27849,6 +27868,7 @@ - id: "s_3746" - name: "lipid backbone" - compartment: "c" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -27856,6 +27876,7 @@ - id: "s_3747" - name: "lipid chain" - compartment: "c" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -28333,15 +28354,6 @@ - metanetx.chemical: "MNXM4505" - sbo: "SBO:0000247" - deltaG: 10000000 - - !!omap - - id: "s_3784" - - name: "(sulfur carrier)-H" - - compartment: "m" - - formula: "R" - - charge: 0 - - annotation: !!omap - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3785" - name: "L-cysteine" @@ -28356,15 +28368,6 @@ - metanetx.chemical: "MNXM55" - sbo: "SBO:0000247" - deltaG: -15.24 - - !!omap - - id: "s_3786" - - name: "(sulfur carrier)-SH" - - compartment: "m" - - formula: "SR" - - charge: 0 - - annotation: !!omap - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3787" - name: "cholesterol" @@ -28761,42 +28764,6 @@ - metanetx.chemical: "MNXM16" - sbo: "SBO:0000247" - deltaG: 147.48 - - !!omap - - id: "s_3819" - - name: "L-lysine-[histone]" - - compartment: "n" - - formula: "C6H13N2OR2" - - charge: 1 - - annotation: !!omap - - chebi: "CHEBI:29969" - - metanetx.chemical: "MNXM59465" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3820" - - name: "S-adenosyl-L-homocysteine" - - compartment: "n" - - formula: "C14H20N6O5S" - - charge: 0 - - smiles: "C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CSCCC(C(=O)O)N)O)O)N" - - annotation: !!omap - - bigg.metabolite: "ahcys" - - chebi: "CHEBI:16680" - - kegg.compound: "C00021" - - metanetx.chemical: "MNXM19" - - sbo: "SBO:0000247" - - deltaG: 109.37 - - !!omap - - id: "s_3821" - - name: "N6-methyl-L-lysine-[histone]" - - compartment: "n" - - formula: "C7H15N2OR2" - - charge: 1 - - annotation: !!omap - - chebi: "CHEBI:61929" - - metanetx.chemical: "MNXM63025" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3822" - name: "Zn(2+)" @@ -28827,7 +28794,7 @@ - deltaG: 10000000 - !!omap - id: "s_3826" - - name: "Ferricytochrome b5" + - name: "ferricytochrome b5" - compartment: "m" - formula: "Fe" - charge: 3 @@ -28840,7 +28807,7 @@ - deltaG: 10000000 - !!omap - id: "s_3827" - - name: "Ferrocytochrome b5" + - name: "ferrocytochrome b5" - compartment: "m" - formula: "Fe" - charge: 2 @@ -28874,18 +28841,6 @@ - metanetx.chemical: "MNXM2349" - sbo: "SBO:0000247" - deltaG: 103.13 - - !!omap - - id: "s_3830" - - name: "RX" - - compartment: "er" - - formula: "RX" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:17792" - - kegg.compound: "C01322" - - metanetx.chemical: "MNXM6428" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3831" - name: "glutathione" @@ -28900,68 +28855,6 @@ - metanetx.chemical: "MNXM57" - sbo: "SBO:0000247" - deltaG: -70.58 - - !!omap - - id: "s_3832" - - name: "HX" - - compartment: "er" - - formula: "X" - - charge: -1 - - smiles: "C1=NC2=C(N1)C(=O)NC=N2" - - annotation: !!omap - - chebi: "CHEBI:16042" - - kegg.compound: "C00462" - - metanetx.chemical: "MNXM55844" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3833" - - name: "R-S-glutathione" - - compartment: "er" - - formula: "C10H16N3O6SR" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:17021" - - kegg.compound: "C02320" - - metanetx.chemical: "MNXM3350" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3834" - - name: "RX" - - compartment: "c" - - formula: "RX" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:17792" - - kegg.compound: "C01322" - - metanetx.chemical: "MNXM6428" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3835" - - name: "HX" - - compartment: "c" - - formula: "X" - - charge: -1 - - smiles: "C1=NC2=C(N1)C(=O)NC=N2" - - annotation: !!omap - - chebi: "CHEBI:16042" - - kegg.compound: "C00462" - - metanetx.chemical: "MNXM55844" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3836" - - name: "R-S-glutathione" - - compartment: "c" - - formula: "C10H16N3O6SR" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:17021" - - kegg.compound: "C02320" - - metanetx.chemical: "MNXM3350" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3837" - name: "L-Methionine S-oxide" @@ -29029,18 +28922,6 @@ - metanetx.chemical: "MNXM4918" - sbo: "SBO:0000247" - deltaG: -151.3 - - !!omap - - id: "s_3842" - - name: "RX" - - compartment: "p" - - formula: "RX" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:17792" - - kegg.compound: "C01322" - - metanetx.chemical: "MNXM6428" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3843" - name: "glutathione" @@ -29055,31 +28936,6 @@ - metanetx.chemical: "MNXM57" - sbo: "SBO:0000247" - deltaG: -70.58 - - !!omap - - id: "s_3844" - - name: "HX" - - compartment: "p" - - formula: "X" - - charge: -1 - - smiles: "C1=NC2=C(N1)C(=O)NC=N2" - - annotation: !!omap - - chebi: "CHEBI:16042" - - kegg.compound: "C00462" - - metanetx.chemical: "MNXM55844" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3845" - - name: "R-S-glutathione" - - compartment: "p" - - formula: "C10H16N3O6SR" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:17021" - - kegg.compound: "C02320" - - metanetx.chemical: "MNXM3350" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3846" - name: "dehydroascorbate" @@ -29176,30 +29032,6 @@ - metanetx.chemical: "MNXM722712" - sbo: "SBO:0000247" - deltaG: -307.29 - - !!omap - - id: "s_3853" - - name: "R-S-Cysteinylglycine" - - compartment: "c" - - formula: "C5H9N2O3SR" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:8744" - - kegg.compound: "C05729" - - metanetx.chemical: "MNXM7734" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3854" - - name: "S-Substituted L-cysteine" - - compartment: "c" - - formula: "C3H6NO2SR" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:47910" - - kegg.compound: "C05726" - - metanetx.chemical: "MNXM96107" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3855" - name: "iron(3+)" @@ -29328,30 +29160,6 @@ - metanetx.chemical: "MNXM396" - sbo: "SBO:0000247" - deltaG: -48.81 - - !!omap - - id: "s_3865" - - name: "sterols" - - compartment: "e" - - formula: "C19H31OR" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:15889" - - kegg.compound: "C00370" - - metanetx.chemical: "MNXM82761" - - sbo: "SBO:0000247" - - deltaG: 201.61 - - !!omap - - id: "s_3866" - - name: "sterols" - - compartment: "c" - - formula: "C19H31OR" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:15889" - - kegg.compound: "C00370" - - metanetx.chemical: "MNXM82761" - - sbo: "SBO:0000247" - - deltaG: 201.61 - !!omap - id: "s_3867" - name: "2-Phenylacetamide" @@ -29449,30 +29257,6 @@ - metanetx.chemical: "MNXM341" - sbo: "SBO:0000247" - deltaG: -161.75 - - !!omap - - id: "s_3876" - - name: "Protein C-terminal S-farnesyl-L-cysteine" - - compartment: "c" - - formula: "C20H32N2O3SR" - - charge: -1 - - annotation: !!omap - - chebi: "CHEBI:17171" - - kegg.compound: "C04506" - - metanetx.chemical: "MNXM5285" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3877" - - name: "Protein C-terminal S-farnesyl-L-cysteine methyl ester" - - compartment: "c" - - formula: "C21H35N2O3SR" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:15818" - - kegg.compound: "C04748" - - metanetx.chemical: "MNXM6400" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3878" - name: "1-phosphatidyl-1D-myo-inositol" @@ -29553,28 +29337,6 @@ - metanetx.chemical: "MNXM7" - sbo: "SBO:0000247" - deltaG: -356.59 - - !!omap - - id: "s_3884" - - name: "generic protein" - - compartment: "c" - - formula: "C2H4NOR" - - charge: 1 - - annotation: !!omap - - kegg.compound: "C00017" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3885" - - name: "L-Arginyl-protein" - - compartment: "c" - - formula: "C8H17N5O2R" - - charge: 2 - - annotation: !!omap - - chebi: "CHEBI:17518" - - kegg.compound: "C16739" - - metanetx.chemical: "MNXM73312" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3887" - name: "G00008" @@ -29723,41 +29485,6 @@ - metanetx.chemical: "MNXM189" - sbo: "SBO:0000247" - deltaG: -117.34 - - !!omap - - id: "s_3900" - - name: "alpha-D-mannoside" - - compartment: "v" - - formula: "C6H11O6R" - - charge: 0 - - smiles: "C(C1C(C(C(C(O1)O)O)O)O)O" - - annotation: !!omap - - chebi: "CHEBI:27535" - - kegg.compound: "C02603" - - metanetx.chemical: "MNXM3535" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3901" - - name: "alpha-D-mannopyranose" - - compartment: "v" - - formula: "C6H12O6" - - charge: 0 - - smiles: "C(C1C(C(C(C(O1)O)O)O)O)O" - - annotation: !!omap - - chebi: "CHEBI:28729" - - kegg.compound: "C00936" - - metanetx.chemical: "MNXM919" - - sbo: "SBO:0000247" - - deltaG: -117.34 - - !!omap - - id: "s_3902" - - name: "non glycosylated sugar acceptor" - - compartment: "v" - - formula: "HOR" - - charge: 0 - - annotation: !!omap - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3903" - name: "L-Threonylcarbamoyladenylate" @@ -29803,7 +29530,7 @@ - name: "hydrogen sulfide" - compartment: "m" - formula: "HS" - - charge: 0 + - charge: -1 - smiles: "S" - annotation: !!omap - bigg.metabolite: "h2s" @@ -29813,43 +29540,6 @@ - metanetx.chemical: "MNXM124865" - sbo: "SBO:0000247" - deltaG: 10000000 - - !!omap - - id: "s_3907" - - name: "phosphatidate" - - compartment: "m" - - formula: "C5H7O8PR2" - - charge: 0 - - annotation: !!omap - - bigg.metabolite: "pa_EC" - - chebi: "CHEBI:16337" - - kegg.compound: "C00416" - - metanetx.chemical: "MNXM96054" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3908" - - name: "CDP-diacylglycerol" - - compartment: "m" - - formula: "C14H19N3O15P2R2" - - charge: 0 - - annotation: !!omap - - bigg.metabolite: "cdpdag_cho" - - chebi: "CHEBI:17962" - - kegg.compound: "C00269" - - metanetx.chemical: "MNXM201" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3909" - - name: "Sulfur donor" - - compartment: "c" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:80867" - - kegg.compound: "C17023" - - metanetx.chemical: "MNXM4111" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3910" - name: "ADP-5-ethyl-4-methylthiazole-2-carboxylate" @@ -29914,58 +29604,6 @@ - metanetx.chemical: "MNXM207" - sbo: "SBO:0000247" - deltaG: -26.8 - - !!omap - - id: "s_3915" - - name: "(R)-Lipoate" - - compartment: "c" - - formula: "C8H13O2S2" - - charge: -1 - - smiles: "C1CSSC1CCCCC(=O)[O-]" - - annotation: !!omap - - bigg.metabolite: "lipoate" - - chebi: "CHEBI:83088" - - kegg.compound: "C16241" - - metanetx.chemical: "MNXM1484" - - sbo: "SBO:0000247" - - deltaG: 62.4 - - !!omap - - id: "s_3916" - - name: "Lipoyl-AMP" - - compartment: "c" - - formula: "C18H25N5O8PS2" - - charge: -1 - - smiles: "C1CSSC1CCCCC(=O)OP(=O)(O)OCC2C(C(C(O2)N3C=NC4=C(N=CN=C43)N)O)O" - - annotation: !!omap - - bigg.metabolite: "lipoamp" - - chebi: "CHEBI:83091" - - kegg.compound: "C16238" - - metanetx.chemical: "MNXM2392" - - sbo: "SBO:0000247" - - deltaG: -33.67 - - !!omap - - id: "s_3917" - - name: "Apoprotein" - - compartment: "c" - - formula: "NH2R" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:13850" - - kegg.compound: "C16240" - - metanetx.chemical: "MNXM91491" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3918" - - name: "Protein N6-(lipoyl)lysine" - - compartment: "c" - - formula: "C8H14NOS2R" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:80399" - - kegg.compound: "C16237" - - metanetx.chemical: "MNXM96070" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3923" - name: "N-(4-oxoglutarate)-L-cysteinylglycine" @@ -30014,30 +29652,6 @@ - metanetx.chemical: "MNXM43" - sbo: "SBO:0000247" - deltaG: -31.38 - - !!omap - - id: "s_3927" - - name: "ribonucleoside 5'-triphosphate" - - compartment: "c" - - formula: "C5H8O13P3R" - - charge: -4 - - annotation: !!omap - - chebi: "CHEBI:61557" - - kegg.compound: "C03802" - - metanetx.chemical: "MNXM96380" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3928" - - name: "ribonucleoside 5'-phosphate" - - compartment: "c" - - formula: "C5H8O7PR" - - charge: -2 - - annotation: !!omap - - chebi: "CHEBI:58043" - - kegg.compound: "C00171" - - metanetx.chemical: "MNXM80910" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3929" - name: "2'-deoxyribonucleoside 5'-triphosphate" @@ -30140,70 +29754,6 @@ - metanetx.chemical: "MNXM196" - sbo: "SBO:0000247" - deltaG: -45.17 - - !!omap - - id: "s_3937" - - name: "Acyl-CoA" - - compartment: "er" - - formula: "C22H31N7O17P3SR" - - charge: -4 - - annotation: !!omap - - bigg.metabolite: "acoa" - - chebi: "CHEBI:58342" - - kegg.compound: "C00040" - - metanetx.chemical: "MNXM44" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3938" - - name: "1-acyl-sn-glycerol 3-phosphate" - - compartment: "er" - - formula: "C4H6O7PR" - - charge: -2 - - annotation: !!omap - - bigg.metabolite: "1ag3p_SC" - - chebi: "CHEBI:57970" - - kegg.compound: "C00681" - - metanetx.chemical: "MNXM145527" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3939" - - name: "1,2-diacyl-sn-glycerol 3-phosphate" - - compartment: "er" - - formula: "C5H5O8PR2" - - charge: -2 - - smiles: "CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])[O-])OC(=O)CCCCCCCCCCCCCCC.[Na+].[Na+]" - - annotation: !!omap - - bigg.metabolite: "pa_EC" - - chebi: "CHEBI:58608" - - kegg.compound: "C00416" - - metanetx.chemical: "MNXM96054" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3940" - - name: "Peptide diphthine" - - compartment: "c" - - formula: "C13H20N4O3R2" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:18054" - - kegg.compound: "C01573" - - metanetx.chemical: "MNXM3980" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3941" - - name: "Peptide diphthamide" - - compartment: "c" - - formula: "C13H22N5O2R2" - - charge: 1 - - annotation: !!omap - - chebi: "CHEBI:82696" - - kegg.compound: "C02872" - - metanetx.chemical: "MNXM51194" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3942" - name: "8-oxo-dGTP" @@ -30228,55 +29778,6 @@ - metanetx.chemical: "MNXM2497" - sbo: "SBO:0000247" - deltaG: -184.19 - - !!omap - - id: "s_3944" - - name: "Apoprotein" - - compartment: "m" - - formula: "NH2R" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:13850" - - kegg.compound: "C16240" - - metanetx.chemical: "MNXM91491" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3945" - - name: "Protein N6-(octanoyl)lysine" - - compartment: "m" - - formula: "C8H16NOR" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:80398" - - kegg.compound: "C16236" - - metanetx.chemical: "MNXM4090" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3946" - - name: "Lipoyl-[acp]" - - compartment: "m" - - formula: "C8H13OS3R" - - charge: 0 - - annotation: !!omap - - bigg.metabolite: "lipACP" - - chebi: "CHEBI:80400" - - kegg.compound: "C16239" - - metanetx.chemical: "MNXM19093" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3947" - - name: "Protein N6-(lipoyl)lysine" - - compartment: "m" - - formula: "C8H14NOS2R" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:80399" - - kegg.compound: "C16237" - - metanetx.chemical: "MNXM96070" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3948" - name: "beta-D-Fructose 6-phosphate" @@ -30741,28 +30242,6 @@ - metanetx.chemical: "MNXM3989" - sbo: "SBO:0000247" - deltaG: 216.48 - - !!omap - - id: "s_3985" - - name: "phospholipid" - - compartment: "erm" - - formula: "C5H6O8PR3" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:16247" - - kegg.compound: "C00865" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_3986" - - name: "phospholipid" - - compartment: "gm" - - formula: "C5H6O8PR3" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:16247" - - kegg.compound: "C00865" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_3987" - name: "ADP" @@ -30962,55 +30441,6 @@ - metanetx.chemical: "MNXM9266" - sbo: "SBO:0000247" - deltaG: 10000000 - - !!omap - - id: "s_4004" - - name: "Sulfur donor" - - compartment: "m" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:80867" - - kegg.compound: "C17023" - - metanetx.chemical: "MNXM4111" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_4005" - - name: "5'-Deoxyadenosine" - - compartment: "m" - - formula: "C10H13N5O3" - - charge: 0 - - smiles: "CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O" - - annotation: !!omap - - bigg.metabolite: "dad_5" - - chebi: "CHEBI:17319" - - kegg.compound: "C05198" - - metanetx.chemical: "MNXM316" - - sbo: "SBO:0000247" - - deltaG: 117.75 - - !!omap - - id: "s_4006" - - name: "S-sulfanyl-[L-cysteine desulfurase]" - - compartment: "m" - - charge: 0 - - annotation: !!omap - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_4007" - - name: "[disordered-form [Fe-S] cluster scaffold protein]" - - compartment: "m" - - charge: 0 - - annotation: !!omap - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_4008" - - name: "S-sulfanyl-[cysteine desulfurase]-[disordered-form scaffold protein] complex" - - compartment: "m" - - charge: 0 - - annotation: !!omap - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_4009" - name: "hydrogen cyanide" @@ -31266,43 +30696,6 @@ - metanetx.chemical: "MNXM149" - sbo: "SBO:0000247" - deltaG: 10000000 - - !!omap - - id: "s_4028" - - name: "RX" - - compartment: "m" - - formula: "RX" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:17792" - - kegg.compound: "C01322" - - metanetx.chemical: "MNXM6428" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_4029" - - name: "HX" - - compartment: "m" - - formula: "X" - - charge: -1 - - smiles: "C1=NC2=C(N1)C(=O)NC=N2" - - annotation: !!omap - - chebi: "CHEBI:16042" - - kegg.compound: "C00462" - - metanetx.chemical: "MNXM55844" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_4030" - - name: "R-S-glutathione" - - compartment: "m" - - formula: "C10H16N3O6SR" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:17021" - - kegg.compound: "C02320" - - metanetx.chemical: "MNXM3350" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_4031" - name: "iron(3+)" @@ -31317,28 +30710,6 @@ - metanetx.chemical: "MNXM196" - sbo: "SBO:0000247" - deltaG: -45.17 - - !!omap - - id: "s_4032" - - name: "[protein]-L-lysine" - - compartment: "c" - - formula: "C6H13N2O" - - charge: 1 - - annotation: !!omap - - bigg.metabolite: "pcollglys" - - chebi: "CHEBI:29969" - - kegg.compound: "C02188" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_4033" - - name: "[protein]-N(6)-acetyl-L-lysine" - - compartment: "c" - - formula: "C8H14N2O2" - - charge: 0 - - annotation: !!omap - - chebi: "CHEBI:61930" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_4034" - name: "Ala-Gln" @@ -33617,6 +32988,7 @@ - id: "s_4205" - name: "cofactor" - compartment: "c" + - charge: 0 - smiles: "C1C2CN(CN2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]" - annotation: !!omap - sbo: "SBO:0000649" @@ -33625,6 +32997,7 @@ - id: "s_4206" - name: "ion" - compartment: "c" + - charge: 0 - annotation: !!omap - sbo: "SBO:0000649" - deltaG: 10000000 @@ -33643,22 +33016,36 @@ - deltaG: -32.21 - !!omap - id: "s_4209" - - name: "Ferrocytochrome b5" + - name: "ferrocytochrome b5" - compartment: "erm" + - formula: "Fe" + - charge: 3 - annotation: !!omap + - bigg.metabolite: "ficytb5" + - chebi: "CHEBI:18097" + - kegg.compound: "C00996" + - metanetx.chemical: "MNXM1083" - sbo: "SBO:0000247" - deltaG: 10000000 - !!omap - id: "s_4210" - - name: "Ferricytochrome b5" + - name: "ferricytochrome b5" - compartment: "erm" + - formula: "Fe" + - charge: 3 - annotation: !!omap + - bigg.metabolite: "ficytb5" + - chebi: "CHEBI:18097" + - kegg.compound: "C00996" + - metanetx.chemical: "MNXM1083" - sbo: "SBO:0000247" - deltaG: 10000000 - !!omap - id: "s_4211" - name: "hexanoyl-CoA" - compartment: "m" + - formula: "C27H46N7O17P3S" + - charge: 0 - smiles: "CCCCCC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O" - annotation: !!omap - sbo: "SBO:0000247" @@ -34200,7 +33587,7 @@ - name: "hydrogen sulfide" - compartment: "e" - formula: "HS" - - charge: 0 + - charge: -1 - smiles: "S" - annotation: !!omap - bigg.metabolite: "h2s" @@ -34225,32 +33612,6 @@ - metanetx.chemical: "MNXM1214" - sbo: "SBO:0000247" - deltaG: -79.97 - - !!omap - - id: "s_4265" - - name: "alkanesulfonate" - - compartment: "c" - - formula: "CH3O3SR" - - charge: 0 - - annotation: !!omap - - biocyc: "Alkanesulfonates" - - chebi: "CHEBI:62081" - - kegg.compound: "C15521" - - metanetx.chemical: "MNXM729199" - - sbo: "SBO:0000247" - - deltaG: 10000000 - - !!omap - - id: "s_4266" - - name: "alkanesulfonate" - - compartment: "e" - - formula: "CH3O3SR" - - charge: 0 - - annotation: !!omap - - biocyc: "Alkanesulfonates" - - chebi: "CHEBI:62081" - - kegg.compound: "C15521" - - metanetx.chemical: "MNXM729199" - - sbo: "SBO:0000247" - - deltaG: 10000000 - !!omap - id: "s_4267" - name: "taurocholate" @@ -34894,40 +34255,6 @@ - sbo: "SBO:0000247" - seed.compound: "cpd00090" - deltaG: -424.2 - - !!omap - - id: "s_4315" - - name: "deamido-NAD(+)" - - compartment: "p" - - formula: "C21H24N6O15P2" - - charge: -2 - - smiles: "C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)O" - - annotation: !!omap - - bigg.metabolite: "dnad" - - biocyc: "DEAMIDO-NAD" - - chebi: "CHEBI:58437" - - kegg.compound: "C00857" - - metanetx.chemical: "MNXM309" - - pubchem.compound: "45266646" - - sbo: "SBO:0000247" - - seed.compound: "cpd00638" - - deltaG: -361.56 - - !!omap - - id: "s_4316" - - name: "nicotinic acid D-ribonucleotide" - - compartment: "p" - - formula: "C11H12NO9P" - - charge: -2 - - smiles: "C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)O)O)O)C(=O)O" - - annotation: !!omap - - bigg.metabolite: "nicrnt" - - biocyc: "NICOTINATE_NUCLEOTIDE" - - chebi: "CHEBI:15763" - - kegg.compound: "C01185" - - metanetx.chemical: "MNXM194" - - pubchem.compound: "46878382" - - sbo: "SBO:0000247" - - seed.compound: "cpd00873" - - deltaG: -266.32 - !!omap - id: "s_4317" - name: "P(1),P(3)-bis(5'-adenosyl) triphosphate" @@ -35137,6 +34464,31 @@ - metanetx.chemical: "MNXM53309" - sbo: "SBO:0000247" - deltaG: 10000000 + - !!omap + - id: "s_4333" + - name: "sulphate" + - compartment: "m" + - formula: "O4S" + - charge: -2 + - smiles: "[O-]S(=O)(=O)[O-]" + - annotation: !!omap + - bigg.metabolite: "so4" + - chebi: "CHEBI:16189" + - kegg.compound: "C00059" + - metanetx.chemical: "MNXM58" + - sbo: "SBO:0000247" + - deltaG: -178.74 + - !!omap + - id: "s_4334" + - name: "trans-but-2-enoyl-CoA" + - compartment: "p" + - formula: "C25H36N7O17P3S" + - charge: -4 + - smiles: "C/C=C/C(=O)SCCNC(=O)CCNC(=O)[C@@H](C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O" + - annotation: !!omap + - chebi: "CHEBI:50998" + - metanetx.chemical: "MNXM1364409" + - sbo: "SBO:0000247" - reactions: - !!omap - id: "r_0001" @@ -35152,8 +34504,7 @@ - eccodes: - "1.1.2.4" - "1.1.99.-" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "D_LACDcm" - kegg.pathway: @@ -35179,8 +34530,7 @@ - eccodes: - "1.1.2.4" - "1.1.99.-" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "D_LACDm" - kegg.pathway: @@ -35205,8 +34555,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAL060W" - eccodes: "1.1.1.4" - - subsystem: - - "Butanoate metabolism" + - subsystem: "Butanoate metabolism" - annotation: !!omap - bigg.reaction: "BTDD_RR" - kegg.pathway: "sce00650" @@ -35227,8 +34576,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YEL039C and YML054C) or (YJR048W and YML054C)" - eccodes: "1.1.2.3" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "L_LACD2cm" - kegg.pathway: @@ -35252,8 +34600,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YPR165W and YLR342W) or (YPR165W and YGR032W) or (YPR165W and YMR306W)" - eccodes: "2.4.1.34" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - kegg.pathway: - "sce00500" @@ -35276,8 +34623,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGR143W or YPR159W" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - pubmed: "8321211" - sbo: "SBO:0000176" @@ -35293,8 +34639,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL020C" - eccodes: "5.3.1.16" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - bigg.reaction: "PRMICI" - kegg.pathway: @@ -35320,8 +34665,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR037W" - eccodes: "1.2.1.88" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "P5CDm" - kegg.pathway: @@ -35341,8 +34685,9 @@ - s_0294: 1 - s_0311: -1 - s_0722: 1 - - s_0794: 6 - - s_0803: -3 + - s_0794: 2 + - s_0803: -1 + - s_1275: -1 - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 @@ -35350,8 +34695,7 @@ - eccodes: - "1.13.11.54" - "3.1.3.77" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - kegg.pathway: "sce00270" - pubmed: "14506228" @@ -35373,8 +34717,7 @@ - eccodes: - "3.5.4.26" - "5.4.99.28" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "DRTPPD" - kegg.pathway: "sce00740" @@ -35398,8 +34741,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR153W" - eccodes: "1.1.1.302" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - kegg.pathway: "sce00740" - kegg.reaction: "R09376" @@ -35421,8 +34763,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YCL009C and YMR108W) or YMR108W" - eccodes: "2.2.1.6" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "ACHBSm" - kegg.pathway: @@ -35456,8 +34797,7 @@ - "2.5.1.15" - "2.7.6.3" - "4.1.2.25" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - kegg.pathway: "sce00790" - kegg.reaction: "R03503" @@ -35480,8 +34820,7 @@ - "2.6.1.39" - "2.6.1.57" - "2.6.1.7" - - subsystem: - - "Lysine metabolism" + - subsystem: "Lysine metabolism" - annotation: !!omap - bigg.reaction: "AATA" - kegg.pathway: @@ -35517,8 +34856,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR063C" - eccodes: "1.1.1.169" - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "DPR" - kegg.pathway: @@ -35542,8 +34880,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR035W or YBR249C" - eccodes: "2.5.1.54" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "DDPAm" - kegg.pathway: @@ -35574,8 +34911,7 @@ - "2.1.1.201" - "2.1.1.64" - "2.7.-.-" - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - bigg.reaction: "2HPMBQMTm" - kegg.pathway: @@ -35604,8 +34940,7 @@ - "2.1.1.201" - "2.1.1.64" - "2.7.-.-" - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - bigg.reaction: "2HP6MPMOm" - kegg.pathway: @@ -35628,8 +34963,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL009C" - eccodes: "4.2.1.33" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "IPPMIb" - kegg.pathway: @@ -35657,8 +34991,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL104C or YOR108W" - eccodes: "2.3.3.13" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "IPPS" - kegg.pathway: @@ -35687,8 +35020,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL104C" - eccodes: "2.3.3.13" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "IPPSm" - kegg.pathway: @@ -35714,8 +35046,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YHR208W or YJR148W or YGL202W or YHR137W" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - kegg.reaction: "R07396" - metanetx.reaction: "MNXR95923" @@ -35734,8 +35065,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR234W" - eccodes: "4.2.1.36" - - subsystem: - - "Lysine metabolism" + - subsystem: "Lysine metabolism" - annotation: !!omap - kegg.pathway: - "sce00300" @@ -35763,8 +35093,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR001W" - eccodes: "2.3.3.1" - - subsystem: - - "Propanoate metabolism" + - subsystem: "Propanoate metabolism" - annotation: !!omap - bigg.reaction: "MCITSm" - kegg.pathway: @@ -35792,8 +35121,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "2.6.1.42" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "OMCDC" - kegg.pathway: @@ -35821,8 +35149,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "2.6.1.42" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "OMCDCm" - kegg.pathway: @@ -35851,8 +35178,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL064C" - eccodes: "3.1.3.7" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - bigg.reaction: "BPNT" - kegg.pathway: @@ -35878,8 +35204,7 @@ - eccodes: - "3.1.4.17" - "3.1.4.53" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PDE1" - kegg.pathway: "sce00230" @@ -35900,8 +35225,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR360C" - eccodes: "3.1.4.53" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PDE2" - kegg.pathway: "sce00230" @@ -35921,8 +35245,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR360C" - eccodes: "3.1.4.53" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PDE3" - kegg.pathway: "sce00230" @@ -35942,8 +35265,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR360C" - eccodes: "3.1.4.53" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PDE4" - kegg.pathway: "sce00230" @@ -35964,8 +35286,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR360C" - eccodes: "3.1.4.53" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PDE5" - kegg.pathway: "sce00230" @@ -35985,8 +35306,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR487C" - eccodes: "4.1.99.12" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "DB4PS" - kegg.pathway: @@ -36014,8 +35334,7 @@ - "2.7.1.71" - "4.2.1.10" - "4.2.3.4" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "DHQTi" - kegg.pathway: @@ -36044,8 +35363,7 @@ - "2.7.1.71" - "4.2.1.10" - "4.2.3.4" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "DHQS" - kegg.pathway: @@ -36072,8 +35390,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR265W" - eccodes: "1.1.1.102" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - kegg.reaction: "R02978" @@ -36098,8 +35415,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR249C or YDR035W" - eccodes: "2.5.1.54" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "DDPA" - kegg.pathway: @@ -36123,8 +35439,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YPL252C or YDR376W" - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - bigg.reaction: "3OPHB5Hm" - kegg.reaction: "R06865" @@ -36144,8 +35459,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR538W and YDR539W" - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - kegg.reaction: "R06866" - metanetx.reaction: "MNXR94901" @@ -36166,8 +35480,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR231C" - eccodes: "3.7.1.3" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "HKYNH" - kegg.pathway: "sce00380" @@ -36192,8 +35505,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HACD6p" - kegg.reaction: "R04739" @@ -36212,8 +35524,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR025C" - eccodes: "1.13.11.6" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "3HAO" - kegg.pathway: "sce00380" @@ -36236,8 +35547,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER175C" - eccodes: "2.1.1.145" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - pubmed: "15147181" - sbo: "SBO:0000176" @@ -36254,8 +35564,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL009C" - eccodes: "4.2.1.33" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "IPPMIa" - kegg.pathway: @@ -36282,8 +35591,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL018W" - eccodes: "1.1.1.85" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "IPMD" - kegg.pathway: @@ -36314,8 +35622,7 @@ - "4.1.1.1" - "4.1.1.43" - "4.1.1.74" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "3MOBDC" - kegg.pathway: @@ -36340,8 +35647,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR176W" - eccodes: "2.1.2.11" - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "MTMOHT" - kegg.pathway: @@ -36368,8 +35674,7 @@ - "4.1.1.1" - "4.1.1.43" - "4.1.1.74" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "3MOPDC" - kegg.pathway: @@ -36399,8 +35704,7 @@ - "2.7.1.71" - "4.2.1.10" - "4.2.3.4" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "PSCVT" - kegg.pathway: @@ -36426,8 +35730,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR033W" - eccodes: "2.6.1.85" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "ADCS" - kegg.pathway: "sce00790" @@ -36448,8 +35751,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR289W" - eccodes: "4.1.3.38" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "ADCL" - kegg.reaction: "R05553" @@ -36469,8 +35771,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR019W" - eccodes: "2.6.1.19" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "ABTA" - kegg.pathway: @@ -36497,8 +35798,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR053W" - eccodes: "4.2.3.1" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "4HTHRS" - kegg.pathway: @@ -36523,8 +35823,7 @@ - s_0807: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - bigg.reaction: "4HBZFm" - kegg.reaction: "R01301" @@ -36545,8 +35844,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL080C" - eccodes: "4.1.1.-" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "4MOPDC" - kegg.pathway: @@ -36576,8 +35874,7 @@ - "2.7.4.24" - "3.6.1.52" - "3.6.1.60" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.reaction: "R05779" - metanetx.reaction: "MNXR103044" @@ -36599,8 +35896,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR017C" - eccodes: "2.7.4.21" - - subsystem: - - "Phosphatidylinositol signaling system" + - subsystem: "Phosphatidylinositol signaling system" - annotation: !!omap - kegg.pathway: - "sce04070" @@ -36622,8 +35918,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR017W" - eccodes: "2.4.2.28" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "MTAP" - kegg.pathway: "sce00270" @@ -36645,8 +35940,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER037W or YGL224C" - eccodes: "3.1.3.-" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NTD4" - kegg.pathway: "sce00760" @@ -36670,8 +35964,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR155C" - eccodes: "3.1.3.99" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTD11" - kegg.pathway: @@ -36695,8 +35988,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER037W or YGL224C" - eccodes: "3.1.3.-" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NTD2" - kegg.pathway: "sce00760" @@ -36725,8 +36017,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR061C" - eccodes: "6.3.5.3" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PRFGS" - kegg.pathway: @@ -36751,8 +36042,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YGL125W and YPL023C) or YGL125W" - eccodes: "1.5.1.20" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "MTHFR3" - kegg.pathway: @@ -36779,8 +36069,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR232W" - eccodes: "2.3.1.37" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "ALASm" - kegg.pathway: @@ -36807,8 +36096,7 @@ - eccodes: - "3.6.1.52" - "3.6.1.60" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.reaction: "R05779" - metanetx.reaction: "MNXR103044" @@ -36829,8 +36117,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR017C" - eccodes: "2.7.4.21" - - subsystem: - - "Phosphatidylinositol signaling system" + - subsystem: "Phosphatidylinositol signaling system" - annotation: !!omap - kegg.pathway: - "sce04070" @@ -36855,8 +36142,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER183C" - eccodes: "6.3.3.2" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "FTHFCL" - kegg.pathway: "sce00670" @@ -36877,8 +36163,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER091C" - eccodes: "2.1.1.14" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "MHPGLUT" - kegg.pathway: @@ -36902,8 +36187,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR024C" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "MDRPD" - kegg.reaction: "R07392" @@ -36922,8 +36206,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YPR118W" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "MTRI" - kegg.reaction: "R04420" @@ -36947,8 +36230,7 @@ - eccodes: - "2.7.4.21" - "2.7.4.24" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "17412958" - sbo: "SBO:0000176" @@ -36969,8 +36251,7 @@ - eccodes: - "2.7.4.21" - "2.7.4.24" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "17412958" - sbo: "SBO:0000176" @@ -36989,8 +36270,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL107C or YOL136C" - eccodes: "2.7.1.105" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - bigg.reaction: "PFK26" - kegg.pathway: "sce00051" @@ -37010,8 +36290,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR248W or YHR163W" - eccodes: "3.1.1.31" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "PGL" - kegg.pathway: @@ -37042,8 +36321,7 @@ - "2.7.4.24" - "3.6.1.52" - "3.6.1.60" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.reaction: "R05779" - metanetx.reaction: "MNXR103044" @@ -37065,8 +36343,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR017C" - eccodes: "2.7.4.21" - - subsystem: - - "Phosphatidylinositol signaling system" + - subsystem: "Phosphatidylinositol signaling system" - annotation: !!omap - kegg.pathway: - "sce04070" @@ -37088,8 +36365,7 @@ - s_1368: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Biotin metabolism" + - subsystem: "Biotin metabolism" - annotation: !!omap - kegg.reaction: "R03210" - metanetx.reaction: "MNXR95854" @@ -37112,8 +36388,7 @@ - "4.1.1.1" - "4.1.1.43" - "4.1.1.74" - - subsystem: - - "Butanoate metabolism" + - subsystem: "Butanoate metabolism" - annotation: !!omap - bigg.reaction: "ACALDCD" - kegg.pathway: @@ -37138,8 +36413,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR355C" - eccodes: "1.1.1.86" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - kegg.pathway: - "sce00290" @@ -37164,8 +36438,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YCL009C and YMR108W) or YMR108W" - eccodes: "2.2.1.6" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - kegg.pathway: - "sce00290" @@ -37193,8 +36466,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKL192C" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "ACOATAm" - kegg.pathway: "sce00190" @@ -37216,8 +36488,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACACT8p" - kegg.pathway: @@ -37244,8 +36515,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACACT9p" - kegg.pathway: @@ -37272,8 +36542,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACACT7p" - kegg.pathway: @@ -37300,8 +36569,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL028W" - eccodes: "2.3.1.9" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACACT1r" - kegg.pathway: @@ -37335,8 +36603,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL028W" - eccodes: "2.3.1.9" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACACT1m" - kegg.pathway: @@ -37371,8 +36638,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACACT6p" - kegg.pathway: @@ -37400,8 +36666,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACACT4p" - kegg.pathway: @@ -37429,8 +36694,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -37462,8 +36726,7 @@ - eccodes: - "6.3.4.14" - "6.4.1.2" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "ACCOACrm" - kegg.pathway: @@ -37493,8 +36756,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL141W and YNR016C" - eccodes: "6.3.4.14" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "ACCOAC" - kegg.pathway: @@ -37522,8 +36784,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL015W" - eccodes: "3.1.2.1" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "ACOAHim" - kegg.pathway: "sce00620" @@ -37546,8 +36807,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAL054C or YLR153C" - eccodes: "6.2.1.1" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "ACS" - kegg.pathway: @@ -37577,8 +36837,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAL054C" - eccodes: "6.2.1.1" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "ACSm" - kegg.pathway: @@ -37607,8 +36866,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR153C" - eccodes: "6.2.1.1" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -37637,8 +36895,7 @@ - eccodes: - "1.2.1.38" - "2.7.2.8" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "ACGKm" - kegg.pathway: @@ -37664,8 +36921,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR093C or YAR071W or YBR092C or YHR215W" - eccodes: "3.1.3.2" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "ACP1e" - kegg.pathway: @@ -37688,8 +36944,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR002W" - eccodes: "4.2.1.79" - - subsystem: - - "Propanoate metabolism" + - subsystem: "Propanoate metabolism" - annotation: !!omap - bigg.reaction: "ACONT3m" - kegg.pathway: "sce00640" @@ -37710,8 +36965,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL140W" - eccodes: "2.6.1.11" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "ACOTAim" - kegg.pathway: @@ -37738,8 +36992,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL148C" - eccodes: "2.7.8.7" - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "ACPSm" - kegg.reaction: "R10747" @@ -37759,8 +37012,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -37784,8 +37036,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACOAO5p" - kegg.pathway: @@ -37810,8 +37061,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACOAO9p" - kegg.pathway: @@ -37836,8 +37086,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACOAO7p" - kegg.pathway: @@ -37862,8 +37111,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACOAO8p" - kegg.pathway: @@ -37888,8 +37136,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACOAO6p" - kegg.pathway: @@ -37914,8 +37161,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR048W" - eccodes: "2.3.1.26" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - pubmed: "10672016" @@ -37934,8 +37180,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR048W or YNR019W" - eccodes: "2.3.1.26" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - metanetx.reaction: "MNXR119161" @@ -37956,8 +37201,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR048W" - eccodes: "2.3.1.26" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - pubmed: "10672016" @@ -37976,8 +37220,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR048W" - eccodes: "2.3.1.26" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - metanetx.reaction: "MNXR119159" @@ -37998,8 +37241,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR048W" - eccodes: "2.3.1.26" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - pubmed: "10672016" @@ -38018,8 +37260,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR048W" - eccodes: "2.3.1.26" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - pubmed: "10672016" @@ -38038,8 +37279,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR048W or YNR019W" - eccodes: "2.3.1.26" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - pubmed: "10672016" @@ -38058,8 +37298,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR048W" - eccodes: "2.3.1.26" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - pubmed: "10672016" @@ -38078,8 +37317,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR048W" - eccodes: "2.3.1.26" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - pubmed: "10672016" @@ -38098,8 +37336,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR048W" - eccodes: "2.3.1.26" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - pubmed: "10672016" @@ -38118,8 +37355,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL091C" - eccodes: "2.3.-.-" - - subsystem: - - "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" + - subsystem: "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" - annotation: !!omap - kegg.pathway: "sce00563" - pubmed: "12714589" @@ -38139,8 +37375,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL141W" - eccodes: "3.5.4.2" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADD" - kegg.pathway: "sce00230" @@ -38161,8 +37396,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR441C or YML022W" - eccodes: "2.4.2.7" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADPT" - kegg.pathway: "sce00230" @@ -38185,8 +37419,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL141W" - eccodes: "3.5.4.2" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADA" - kegg.pathway: "sce00230" @@ -38208,8 +37441,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR105W" - eccodes: "2.7.1.20" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADNK1" - kegg.pathway: "sce00230" @@ -38231,8 +37463,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML035C" - eccodes: "3.5.4.6" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "AMPDA" - kegg.pathway: @@ -38256,8 +37487,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER043C" - eccodes: "3.3.1.1" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "AHCi" - kegg.pathway: "sce00270" @@ -38279,8 +37509,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL052C" - eccodes: "4.1.1.50" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "ADMDC" - kegg.pathway: @@ -38304,8 +37533,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR058W" - eccodes: "2.6.1.62" - - subsystem: - - "Biotin metabolism" + - subsystem: "Biotin metabolism" - annotation: !!omap - bigg.reaction: "AMAOTr" - kegg.pathway: "sce00780" @@ -38325,8 +37553,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL005W" - eccodes: "4.6.1.1" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADNCYC" - kegg.pathway: @@ -38349,8 +37576,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL166C or YDR226W" - eccodes: "2.7.4.3" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADK1" - kegg.pathway: @@ -38374,8 +37600,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER170W" - eccodes: "2.7.4.10" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADK1m" - kegg.pathway: @@ -38400,8 +37625,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER170W" - eccodes: "2.7.4.10" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADK3m" - kegg.pathway: @@ -38424,8 +37648,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR359W" - eccodes: "4.3.2.2" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADSL2r" - kegg.pathway: @@ -38449,8 +37672,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR359W" - eccodes: "4.3.2.2" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADSL1r" - kegg.pathway: @@ -38478,8 +37700,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL220W" - eccodes: "6.3.4.4" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ADSS" - kegg.pathway: @@ -38503,8 +37724,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL001C" - eccodes: "2.7.1.25" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - bigg.reaction: "ADSK" - kegg.pathway: @@ -38528,8 +37748,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR247W" - eccodes: "3.1.4.37" - - subsystem: - - "Cyclic nucleotide metabolism" + - subsystem: "Cyclic nucleotide metabolism" - annotation: !!omap - bigg.reaction: "23CAPPD" - metanetx.reaction: "MNXR117324" @@ -38550,8 +37769,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFL030W" - eccodes: "2.6.1.44" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "AGTi" - kegg.pathway: @@ -38581,8 +37799,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR335C" - eccodes: "6.1.1.7" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "ALATRS" - kegg.pathway: "sce00970" @@ -38604,8 +37821,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR177C or YOR377W" - eccodes: "2.3.1.84" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "OHACT3" - metanetx.reaction: "MNXR102165" @@ -38625,8 +37841,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR177C or YOR377W" - eccodes: "2.3.1.84" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - metanetx.reaction: "MNXR117501" - pubmed: "12957907" @@ -38645,8 +37860,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR177C or YOR377W" - eccodes: "2.3.1.84" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "OHACT2" - metanetx.reaction: "MNXR102164" @@ -38666,8 +37880,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR177C or YOR377W" - eccodes: "2.3.1.84" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "OHACT4" - metanetx.reaction: "MNXR102166" @@ -38687,8 +37900,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR177C or YOR377W" - eccodes: "2.3.1.84" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "OHACT5" - metanetx.reaction: "MNXR102167" @@ -38709,8 +37921,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR303C" - eccodes: "1.1.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "ALCD2x" - kegg.pathway: @@ -38740,8 +37951,7 @@ - eccodes: - "1.1.1.-" - "1.1.1.21" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - bigg.reaction: "ALCD19y" - kegg.pathway: "sce00040" @@ -38764,8 +37974,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL256W or YMR083W" - eccodes: "1.1.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "ALCD2irm" - kegg.pathway: @@ -38796,8 +38005,7 @@ - "1.1.1.-" - "1.1.1.1" - "1.1.1.284" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ALCD22xi" - kegg.pathway: @@ -38825,8 +38033,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL256W or YMR083W" - eccodes: "1.1.1.1" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ALCD22xim" - kegg.pathway: @@ -38855,8 +38062,7 @@ - eccodes: - "1.1.1.-" - "1.1.1.2" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ALCD22yi" - kegg.pathway: @@ -38888,8 +38094,7 @@ - "1.1.1.-" - "1.1.1.1" - "1.1.1.284" - - subsystem: - - "Phenylalanine metabolism" + - subsystem: "Phenylalanine metabolism" - annotation: !!omap - bigg.reaction: "ALCD25xi" - kegg.pathway: @@ -38918,8 +38123,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL256W or YMR083W" - eccodes: "1.1.1.1" - - subsystem: - - "Phenylalanine metabolism" + - subsystem: "Phenylalanine metabolism" - annotation: !!omap - bigg.reaction: "ALCD25xim" - kegg.pathway: @@ -38947,8 +38151,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR105W or YMR318C" - eccodes: "1.1.1.2" - - subsystem: - - "Phenylalanine metabolism" + - subsystem: "Phenylalanine metabolism" - annotation: !!omap - bigg.reaction: "ALCD25yi" - kegg.pathway: @@ -38979,8 +38182,7 @@ - gene_reaction_rule: "YMR170C or YMR169C" - eccodes: "1.2.1.3" - references: "10.1093/genetics/163.1.69" - - subsystem: - - "Beta-alanine metabolism" + - subsystem: "Beta-alanine metabolism" - annotation: !!omap - bigg.reaction: "ALDD22x" - kegg.pathway: @@ -39010,8 +38212,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL061W" - eccodes: "1.2.1.4" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "ALDD2y" - kegg.pathway: @@ -39047,8 +38248,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR374W" - eccodes: "1.2.1.5" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "ALDD2xm" - kegg.pathway: @@ -39084,8 +38284,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER073W or YOR374W" - eccodes: "1.2.1.5" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "ALDD2ym" - kegg.pathway: @@ -39121,8 +38320,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR374W" - eccodes: "1.2.1.5" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "ALDD20xm" - kegg.pathway: @@ -39157,8 +38355,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL061W" - eccodes: "1.2.1.4" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "ALDD20y" - kegg.pathway: @@ -39192,8 +38389,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER073W or YOR374W" - eccodes: "1.2.1.5" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "ALDD20ym" - kegg.pathway: @@ -39230,8 +38426,7 @@ - "1.1.1.-" - "1.1.1.1" - "1.1.1.284" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ALCD24xi" - kegg.pathway: @@ -39261,8 +38456,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL256W or YMR083W" - eccodes: "1.1.1.1" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ALCD24xim" - kegg.pathway: @@ -39291,8 +38485,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR105W or YMR318C" - eccodes: "1.1.1.2" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ALCD24yi" - kegg.pathway: @@ -39326,8 +38519,7 @@ - "1.1.1.-" - "1.1.1.1" - "1.1.1.284" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ALCD23xi" - kegg.pathway: @@ -39355,8 +38547,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL256W or YMR083W" - eccodes: "1.1.1.1" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ALCD23xim" - kegg.pathway: @@ -39383,8 +38574,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR105W or YMR318C" - eccodes: "1.1.1.2" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ALCD23yi" - kegg.pathway: @@ -39414,8 +38604,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR169C or YMR170C" - eccodes: "1.2.1.3" - - subsystem: - - "Phenylalanine metabolism" + - subsystem: "Phenylalanine metabolism" - annotation: !!omap - bigg.reaction: "ALDD19xr" - kegg.pathway: @@ -39447,8 +38636,7 @@ - "1.1.1.-" - "1.1.1.1" - "1.1.1.284" - - subsystem: - - "Tyrosine metabolism" + - subsystem: "Tyrosine metabolism" - annotation: !!omap - bigg.reaction: "ALCD26xi" - kegg.pathway: @@ -39477,8 +38665,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL256W or YMR083W" - eccodes: "1.1.1.1" - - subsystem: - - "Tyrosine metabolism" + - subsystem: "Tyrosine metabolism" - annotation: !!omap - bigg.reaction: "ALCD26xim" - kegg.pathway: @@ -39509,8 +38696,7 @@ - "3.1.3.1" - "3.1.3.54" - "3.1.7.6" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "AKP1" - kegg.pathway: @@ -39534,8 +38720,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIR029W" - eccodes: "3.5.3.4" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ALLTAHr" - kegg.pathway: "sce00230" @@ -39558,8 +38743,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIR027C" - eccodes: "3.5.2.5" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ALLTN" - kegg.pathway: "sce00230" @@ -39584,8 +38768,7 @@ - eccodes: - "3.5.1.54" - "6.3.4.6" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "ALPHNH" - kegg.pathway: @@ -39609,8 +38792,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR199W or YBR205W or YDR483W or YJL139C or YKR061W or YNL029C or YOR099W or YPL053C" - eccodes: "2.4.1.-" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00513" @@ -39637,8 +38819,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR026W or YBR001C" - eccodes: "3.2.1.28" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "TREHv" - kegg.pathway: "sce00500" @@ -39658,8 +38839,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR001C" - eccodes: "3.2.1.28" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "TREH" - kegg.pathway: "sce00500" @@ -39684,8 +38864,7 @@ - eccodes: - "2.4.1.15" - "3.1.3.12" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "TRE6PS" - kegg.pathway: "sce00500" @@ -39709,8 +38888,7 @@ - eccodes: - "3.2.1.10" - "3.2.1.20" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "MALT" - kegg.pathway: @@ -39734,8 +38912,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR242W or YMR293C" - eccodes: "6.3.5.7" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "AMID" - kegg.pathway: "sce00970" @@ -39756,8 +38933,7 @@ - s_1275: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "AACTOOR" - kegg.reaction: "R02529" @@ -39780,8 +38956,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR374W" - eccodes: "1.2.1.5" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "ABUTDm" - kegg.pathway: @@ -39814,8 +38989,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR354W" - eccodes: "2.4.2.18" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "ANPRT" - kegg.pathway: @@ -39842,8 +39016,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER090W and YKL211C" - eccodes: "4.1.3.27" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "ANS" - kegg.pathway: @@ -39869,8 +39042,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR305C" - eccodes: "3.6.1.29" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "AP4AH" - kegg.pathway: "sce00230" @@ -39894,8 +39066,7 @@ - eccodes: - "1.1.1.-" - "1.1.1.21" - - subsystem: - - "Pentose and glucuronate interconversions" + - subsystem: "Pentose and glucuronate interconversions" - annotation: !!omap - bigg.reaction: "ARABR" - kegg.pathway: "sce00040" @@ -39916,8 +39087,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL111W" - eccodes: "3.5.3.1" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "ARGN" - kegg.pathway: @@ -39942,8 +39112,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR018C" - eccodes: "4.3.2.1" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "ARGSL" - kegg.pathway: @@ -39973,8 +39142,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL058W" - eccodes: "6.3.4.5" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "ARGSS" - kegg.pathway: @@ -40004,8 +39172,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR341C" - eccodes: "6.1.1.19" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "ARGTRS" - kegg.pathway: "sce00970" @@ -40028,8 +39195,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR091C" - eccodes: "6.1.1.19" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "ARGTRSm" - kegg.pathway: "sce00970" @@ -40055,8 +39221,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR124W or YPR145W" - eccodes: "6.3.5.4" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "ASNS1" - kegg.pathway: @@ -40082,8 +39247,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR019C" - eccodes: "6.1.1.22" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "ASNTRS" - kegg.pathway: "sce00970" @@ -40107,8 +39271,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR024C" - eccodes: "6.1.1.22" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "ASNTRSm" - kegg.pathway: "sce00970" @@ -40133,8 +39296,7 @@ - eccodes: - "2.1.3.2" - "6.3.5.5" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "ASPCT" - kegg.pathway: @@ -40157,8 +39319,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER052C" - eccodes: "2.7.2.4" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "ASPK" - kegg.pathway: @@ -40188,8 +39349,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR027C" - eccodes: "2.6.1.1" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "ASPTA" - kegg.pathway: @@ -40224,8 +39384,7 @@ - gene_reaction_rule: "YKL106W" - eccodes: "2.6.1.1" - references: "10.1016/j.femsyr.2004.09.008" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "ASPTAm" - kegg.pathway: @@ -40260,8 +39419,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR027C" - eccodes: "2.6.1.1" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "ASPTAp" - kegg.pathway: @@ -40297,8 +39455,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR158W" - eccodes: "1.2.1.11" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "ASAD" - kegg.pathway: @@ -40330,8 +39487,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL018C" - eccodes: "6.1.1.12" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "ASPTRS" - kegg.pathway: "sce00970" @@ -40355,8 +39511,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL104W" - eccodes: "6.1.1.12" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "ASPTRSm" - kegg.pathway: "sce00970" @@ -40381,8 +39536,7 @@ - eccodes: - "2.7.7.5" - "2.7.7.53" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ATPATF1" - kegg.pathway: "sce00230" @@ -40404,8 +39558,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL050C" - eccodes: "2.7.7.53" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ATPATF2" - kegg.pathway: @@ -40428,8 +39581,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL050C" - eccodes: "2.7.7.53" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ATPATF3" - kegg.pathway: @@ -40451,8 +39603,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER055C" - eccodes: "2.4.2.17" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - bigg.reaction: "ATPPRT" - kegg.pathway: @@ -40474,12 +39625,11 @@ - s_0799: 2 - s_0807: 1 - s_1326: -1 - - lower_bound: 0 + - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "Q0080 and Q0085 and Q0130 and YBL099W and YBR039W and YDL004W and YDR298C and YDR377W and YJR121W and YKL016C and YLR295C and YML081C-A and YPL078C and YPL271W and YDR322C-A and YPR020W and YOL077W-A" - eccodes: "3.6.3.14" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - bigg.reaction: "ATPS3m" - kegg.pathway: "sce00190" @@ -40492,7 +39642,7 @@ - confidence_score: 3 - !!omap - id: "r_0227" - - name: "ATPase, cytosolic" + - name: "ATPase, plasma membrane" - metabolites: !!omap - s_0394: 1 - s_0434: -1 @@ -40505,8 +39655,7 @@ - eccodes: - "3.6.1.5" - "3.6.3.6" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ATPS" - kegg.pathway: @@ -40532,8 +39681,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR110W" - eccodes: "2.4.1.142" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00510" @@ -40557,8 +39705,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR286C" - eccodes: "2.8.1.6" - - subsystem: - - "Biotin metabolism" + - subsystem: "Biotin metabolism" - annotation: !!omap - kegg.pathway: "sce00780" - sbo: "SBO:0000176" @@ -40582,8 +39729,7 @@ - "6.3.4.11" - "6.3.4.15" - "6.3.4.9" - - subsystem: - - "Biotin metabolism" + - subsystem: "Biotin metabolism" - annotation: !!omap - bigg.reaction: "BACCL" - kegg.pathway: "sce00780" @@ -40606,8 +39752,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL280C" - eccodes: "1.3.1.70" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "C14STR" - kegg.pathway: @@ -40634,8 +39779,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR015C" - eccodes: "1.14.19.41" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "C22STDS" - kegg.pathway: @@ -40659,8 +39803,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL001C" - eccodes: "1.1.1.170" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -40683,8 +39826,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL001C" - eccodes: "1.1.1.170" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -40707,8 +39849,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR100W" - eccodes: "1.1.1.270" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -40731,8 +39872,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR100W" - eccodes: "1.1.1.270" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "HMR_1509" - kegg.pathway: @@ -40757,8 +39897,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR060W" - eccodes: "1.14.13.72" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -40782,8 +39921,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR060W" - eccodes: "1.14.13.72" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "HMR_1503" - kegg.pathway: @@ -40807,8 +39945,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR060W" - eccodes: "1.14.13.72" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -40833,8 +39970,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR060W" - eccodes: "1.14.13.72" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -40860,8 +39996,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR056W" - eccodes: "1.14.19.20" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "C5STDS" - kegg.pathway: @@ -40882,8 +40017,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR202W" - eccodes: "5.-.-.-" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "C8STI" - kegg.pathway: @@ -40907,8 +40041,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL012W" - eccodes: "1.3.1.71" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "C24STRer" - kegg.pathway: @@ -40931,8 +40064,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL090C and YKL019W" - eccodes: "2.5.1.58" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -40963,8 +40095,7 @@ - eccodes: - "2.1.3.2" - "6.3.5.5" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "CBPS" - kegg.pathway: @@ -40984,11 +40115,10 @@ - s_0529: 1 - s_1235: 1 - lower_bound: 0 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YAR035W or YER024W" - eccodes: "2.3.1.7" - - subsystem: - - "Carnitine metabolism" + - subsystem: "Carnitine metabolism" - annotation: !!omap - bigg.reaction: "CSNATr" - kegg.pathway: "sce04146" @@ -40998,6 +40128,7 @@ - sbo: "SBO:0000176" - deltaG: -3.76 - confidence_score: 3 + - rxnNotes: "Only active if growth medium contains carnitine" - !!omap - id: "r_0253" - name: "carnitine O-acetyltransferase" @@ -41010,8 +40141,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML042W" - eccodes: "2.3.1.7" - - subsystem: - - "Carnitine metabolism" + - subsystem: "Carnitine metabolism" - annotation: !!omap - bigg.reaction: "CSNATp" - kegg.pathway: "sce04146" @@ -41032,8 +40162,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML042W" - eccodes: "2.3.1.7" - - subsystem: - - "Carnitine metabolism" + - subsystem: "Carnitine metabolism" - annotation: !!omap - bigg.reaction: "CSNATm" - kegg.pathway: "sce04146" @@ -41053,8 +40182,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR088W" - eccodes: "1.11.1.6" - - subsystem: - - "Glyoxylate and dicarboxylate metabolism" + - subsystem: "Glyoxylate and dicarboxylate metabolism" - annotation: !!omap - bigg.reaction: "CAT" - kegg.pathway: @@ -41084,8 +40212,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR256C" - eccodes: "1.11.1.6" - - subsystem: - - "Glyoxylate and dicarboxylate metabolism" + - subsystem: "Glyoxylate and dicarboxylate metabolism" - annotation: !!omap - bigg.reaction: "CATp" - kegg.pathway: @@ -41118,8 +40245,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR297W" - eccodes: "1.-.-.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - metanetx.reaction: "MNXR126673" @@ -41144,8 +40270,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR272C" - eccodes: "1.-.-.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - metanetx.reaction: "MNXR126668" - pubmed: @@ -41169,8 +40294,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR297W" - eccodes: "1.-.-.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - metanetx.reaction: "MNXR126661" @@ -41195,8 +40319,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR272C" - eccodes: "1.-.-.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - metanetx.reaction: "MNXR126662" - pubmed: @@ -41218,8 +40341,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL008C and YHL003C and YMR298W" - eccodes: "2.3.1.24" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - bigg.reaction: "CERS124er" - kegg.pathway: "sce00600" @@ -41244,8 +40366,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL008C and YHL003C and YMR298W" - eccodes: "2.3.1.24" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - bigg.reaction: "CERS126er" - kegg.pathway: "sce00600" @@ -41272,8 +40393,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL008C and YHL003C and YMR298W" - eccodes: "2.3.1.24" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - bigg.reaction: "CERS224er" - kegg.pathway: "sce00600" @@ -41298,8 +40418,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL008C and YHL003C and YMR298W" - eccodes: "2.3.1.24" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - bigg.reaction: "CERS226er" - kegg.pathway: "sce00600" @@ -41328,8 +40447,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR272C" - eccodes: "1.-.-.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - metanetx.reaction: "MNXR126670" - pubmed: @@ -41353,8 +40471,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR272C" - eccodes: "1.-.-.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - metanetx.reaction: "MNXR126669" - pubmed: @@ -41378,8 +40495,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR272C" - eccodes: "1.-.-.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - metanetx.reaction: "MNXR126672" - pubmed: @@ -41403,8 +40519,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR272C" - eccodes: "1.-.-.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - metanetx.reaction: "MNXR126671" - pubmed: @@ -41426,8 +40541,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR307W or YLR308W" - eccodes: "3.5.1.41" - - subsystem: - - "Amino sugar and nucleotide sugar metabolism" + - subsystem: "Amino sugar and nucleotide sugar metabolism" - annotation: !!omap - kegg.pathway: "sce00520" - kegg.reaction: "R02333" @@ -41448,8 +40562,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR023C or YBR038W or YNL192W" - eccodes: "2.4.1.16" - - subsystem: - - "Amino sugar and nucleotide sugar metabolism" + - subsystem: "Amino sugar and nucleotide sugar metabolism" - annotation: !!omap - kegg.pathway: "sce00520" - kegg.reaction: "R02335" @@ -41471,8 +40584,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR133W" - eccodes: "2.7.1.32" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - bigg.reaction: "CHOLK" - kegg.pathway: "sce00564" @@ -41495,8 +40607,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR202C" - eccodes: "2.7.7.15" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - bigg.reaction: "CHLPCTD" - kegg.pathway: @@ -41517,8 +40628,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR060C" - eccodes: "5.4.99.5" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "CHORM" - kegg.pathway: @@ -41543,8 +40653,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL148W" - eccodes: "4.2.3.5" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "CHORS" - kegg.pathway: @@ -41569,8 +40678,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR304C" - eccodes: "4.2.1.3" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "ACN_b_m" - kegg.pathway: @@ -41599,8 +40707,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41623,8 +40730,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41647,8 +40753,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41671,8 +40776,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41695,8 +40799,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41719,8 +40822,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41743,8 +40845,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41767,8 +40868,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41790,8 +40890,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41812,8 +40911,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41834,8 +40932,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41856,8 +40953,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41878,8 +40974,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41900,8 +40995,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41922,8 +41016,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41944,8 +41037,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41966,8 +41058,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -41988,8 +41079,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -42010,8 +41100,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR002C or YMR101C" - eccodes: "2.5.1.87" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00900" @@ -42034,8 +41123,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR001C or YPR001W" - eccodes: "2.3.3.1" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "CSm" - kegg.pathway: @@ -42066,8 +41154,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR005C" - eccodes: "2.3.3.16" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "CSp" - kegg.pathway: @@ -42095,8 +41182,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR304C" - eccodes: "4.2.1.3" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "ACN_a_m" - kegg.pathway: @@ -42124,8 +41210,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR304C" - eccodes: "4.2.1.3" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "ACONTa" - kegg.pathway: @@ -42156,8 +41241,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR044W" - eccodes: "1.3.3.3" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "CPPPGO" - kegg.pathway: @@ -42185,8 +41269,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL039C or YJR103W" - eccodes: "6.3.4.2" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "CTPS2" - kegg.pathway: "sce00240" @@ -42210,8 +41293,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL039C or YJR103W" - eccodes: "6.3.4.2" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "CTPS1" - kegg.pathway: "sce00240" @@ -42233,8 +41315,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR055W or YGL184C" - eccodes: "4.4.1.8" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "CYSTL" - kegg.pathway: @@ -42260,8 +41341,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR155W" - eccodes: "4.2.1.22" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "CYSTS" - kegg.pathway: @@ -42288,8 +41368,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAL012W" - eccodes: "4.4.1.1" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "CYSTGL" - kegg.pathway: @@ -42317,8 +41396,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR130C" - eccodes: "2.5.1.48" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "METB1" - kegg.pathway: @@ -42349,8 +41427,7 @@ - "2.5.1.47" - "2.5.1.49" - references: "10.1111/j.1574-6968.2003.tb11531.x" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "CYSS" - kegg.pathway: @@ -42383,8 +41460,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL247W" - eccodes: "6.1.1.16" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "CYSTRS" - kegg.pathway: "sce00970" @@ -42407,8 +41483,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR245C" - eccodes: "3.5.4.5" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "CYTD" - kegg.pathway: "sce00240" @@ -42430,8 +41505,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR012W" - eccodes: "2.7.1.48" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "CYTDK2" - kegg.pathway: "sce00240" @@ -42458,8 +41532,7 @@ - eccodes: - "1.14.13.70" - "1.6.2.4" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "LNS14DM" - kegg.pathway: @@ -42485,8 +41558,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR062W" - eccodes: "3.5.4.1" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "CSND" - kegg.pathway: @@ -42510,8 +41582,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML086C" - eccodes: "1.1.3.37" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - kegg.reaction: "R02715" - metanetx.reaction: "MNXR107687" @@ -42533,8 +41604,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR041C" - eccodes: "1.1.1.116" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - bigg.reaction: "ARAB1D1" - kegg.reaction: "R01574" @@ -42556,8 +41626,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR149W" - eccodes: "1.1.1.117" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - bigg.reaction: "ARAB1D2" - kegg.reaction: "R01575" @@ -42576,8 +41645,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL060C" - eccodes: "4.1.2.13" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "FBA2" - kegg.pathway: @@ -42606,8 +41674,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL246C or YJR159W" - eccodes: "1.1.1.14" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - bigg.reaction: "SBTD_D2" - kegg.pathway: @@ -42631,8 +41698,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR144C" - eccodes: "3.5.4.12" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "DCMPDA" - kegg.pathway: "sce00240" @@ -42654,8 +41720,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR144C" - eccodes: "3.5.4.12" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "DCTPD" - kegg.pathway: "sce00240" @@ -42677,8 +41742,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL141W" - eccodes: "3.5.4.2" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "DADA" - kegg.pathway: "sce00230" @@ -42700,8 +41764,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR245C" - eccodes: "3.5.4.5" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "DCYTD" - kegg.pathway: "sce00240" @@ -42722,8 +41785,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR454C" - eccodes: "2.7.4.8" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "DGK1" - kegg.pathway: "sce00230" @@ -42746,8 +41808,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR068W" - eccodes: "2.5.1.46" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - metanetx.reaction: "MNXR136013" - sbo: "SBO:0000176" @@ -42766,8 +41827,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR036W" - eccodes: "2.7.1.15" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "DRBK" - kegg.pathway: "sce00030" @@ -42789,8 +41849,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR196C" - eccodes: "2.7.1.24" - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "DPCOAKm" - kegg.pathway: "sce00770" @@ -42814,8 +41873,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR057C" - eccodes: "6.3.3.3" - - subsystem: - - "Biotin metabolism" + - subsystem: "Biotin metabolism" - annotation: !!omap - bigg.reaction: "DBTS" - kegg.pathway: "sce00780" @@ -42836,8 +41894,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL087W" - eccodes: "3.5.1.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - metanetx.reaction: "MNXR126695" @@ -42860,8 +41917,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL087W" - eccodes: "3.5.1.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -42883,8 +41939,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL087W" - eccodes: "3.5.1.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - metanetx.reaction: "MNXR126696" @@ -42907,8 +41962,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL087W" - eccodes: "3.5.1.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - metanetx.reaction: "MNXR126694" @@ -42932,8 +41986,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR236W" - eccodes: "1.5.1.3" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "DHFR" - kegg.pathway: @@ -42957,8 +42010,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR236W" - eccodes: "1.5.1.3" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "DHFRim" - kegg.pathway: @@ -42984,8 +42036,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR113W" - eccodes: "6.3.2.12" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "DHFS" - kegg.pathway: "sce00790" @@ -43010,8 +42061,7 @@ - "2.5.1.15" - "2.7.6.3" - "4.1.2.25" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - kegg.pathway: "sce00790" - kegg.reaction: "R03504" @@ -43031,8 +42081,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL100C" - eccodes: "3.6.-.-" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "DNMPPA" - kegg.reaction: "R04621" @@ -43053,8 +42102,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR420W" - eccodes: "3.5.2.3" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "DHORTS" - kegg.pathway: "sce00240" @@ -43079,8 +42127,7 @@ - "2.5.1.15" - "2.7.6.3" - "4.1.2.25" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - kegg.pathway: "sce00790" - kegg.reaction: "R03066" @@ -43104,8 +42151,7 @@ - "2.5.1.15" - "2.7.6.3" - "4.1.2.25" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "FOLD3m" - kegg.pathway: "sce00790" @@ -43126,8 +42172,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR016C" - eccodes: "4.2.1.9" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "DHAD1m" - kegg.pathway: @@ -43154,8 +42199,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR016C" - eccodes: "4.2.1.9" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "DHAD2m" - kegg.pathway: @@ -43186,8 +42230,7 @@ - eccodes: - "2.7.1.28" - "2.7.1.29" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - bigg.reaction: "DHAK" - kegg.pathway: @@ -43213,8 +42256,7 @@ - eccodes: - "2.5.1.1" - "2.5.1.10" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "DMATT" - kegg.pathway: @@ -43237,8 +42279,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL152C" - eccodes: "5.4.2.11" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "DPGM" - kegg.pathway: @@ -43269,8 +42310,7 @@ - eccodes: - "3.6.1.52" - "3.6.1.60" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "10419486" - sbo: "SBO:0000176" @@ -43292,8 +42332,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR017C" - eccodes: "2.7.4.21" - - subsystem: - - "Phosphatidylinositol signaling system" + - subsystem: "Phosphatidylinositol signaling system" - annotation: !!omap - kegg.pathway: - "sce04070" @@ -43316,8 +42355,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR172C" - eccodes: "2.1.1.314" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "DIPS" - kegg.reaction: "R04481" @@ -43339,8 +42377,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR013C" - eccodes: "2.7.1.108" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - bigg.reaction: "DOLK" - kegg.pathway: "sce00510" @@ -43363,8 +42400,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR183W" - eccodes: "2.4.1.83" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - bigg.reaction: "DOLPMTcer" - kegg.pathway: "sce00510" @@ -43385,8 +42421,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YAL023C and YDL095W) or YDL093W or YJR143C or YOR321W" - eccodes: "2.4.1.109" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - bigg.reaction: "DOLPMMer" - kegg.pathway: @@ -43409,8 +42444,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR057W" - eccodes: "2.7.4.9" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "DTMPK" - kegg.pathway: "sce00240" @@ -43432,8 +42466,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR069C or YBR252W" - eccodes: "3.6.1.23" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "DUTPDP" - kegg.pathway: "sce00240" @@ -43453,8 +42486,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR153W" - eccodes: "3.2.1.15" - - subsystem: - - "Pentose and glucuronate interconversions" + - subsystem: "Pentose and glucuronate interconversions" - annotation: !!omap - bigg.reaction: "EPGALURSe" - kegg.pathway: "sce00040" @@ -43473,8 +42505,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL281C or YGR254W or YHR174W or YMR323W or YOR393W" - eccodes: "4.2.1.11" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "ENO" - kegg.pathway: @@ -43505,8 +42536,7 @@ - eccodes: - "2.7.1.32" - "2.7.1.82" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - bigg.reaction: "ETHAK" - kegg.pathway: "sce00564" @@ -43529,8 +42559,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - metanetx.reaction: "MNXR121010" - pubmed: "10855721" @@ -43550,8 +42579,7 @@ - eccodes: - "3.2.1.58" - "3.2.1.6" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "13BGHe" - kegg.pathway: "sce00500" @@ -43577,8 +42605,7 @@ - "2.5.1.1" - "2.5.1.10" - "2.5.1.29" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "FRTT" - kegg.pathway: @@ -43605,8 +42632,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER015W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -43631,8 +42657,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER015W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "FACOAL120p" - kegg.pathway: @@ -43658,8 +42683,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER015W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "FACOAL160p" - kegg.pathway: @@ -43686,8 +42710,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER015W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "FACOAL80p" - kegg.pathway: @@ -43713,8 +42736,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER015W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "FACOAL140p" - kegg.pathway: @@ -43738,8 +42760,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR176W" - eccodes: "4.99.1.1" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "FCLTm" - kegg.pathway: @@ -43762,8 +42783,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YEL039C and YKR066C) or (YJR048W and YKR066C)" - eccodes: "1.11.1.5" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - bigg.reaction: "CCP2m" - kegg.pathway: "sce00920" @@ -43787,8 +42807,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(Q0045 and Q0250 and Q0275 and YDL067C and YEL039C and YGL187C and YGL191W and YHR051W and YIL111W and YLR038C and YLR395C and YMR256C) or (Q0045 and Q0250 and Q0275 and YDL067C and YEL039C and YGL187C and YGL191W and YHR051W and YLR038C and YLR395C and YMR256C and YNL052W) or (Q0045 and Q0250 and Q0275 and YDL067C and YGL187C and YGL191W and YHR051W and YIL111W and YJR048W and YLR038C and YLR395C and YMR256C) or (Q0045 and Q0250 and Q0275 and YDL067C and YGL187C and YGL191W and YHR051W and YJR048W and YLR038C and YLR395C and YMR256C and YNL052W) or (Q0045 and Q0250 and Q0275 and YDL067C and YHR116W and YDR231C and YGR062C and YJL003W and YPL132W and YLL018C-A)" - eccodes: "1.9.3.1" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - kegg.pathway: - "sce00190" @@ -43814,8 +42833,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(Q0105 and YBL045C and YDR529C and YEL024W and YEL039C and YFR033C and YGR183C and YHR001W-A and YJL166W and YOR065W and YPR191W) or (Q0105 and YBL045C and YDR529C and YEL024W and YFR033C and YGR183C and YHR001W-A and YJL166W and YJR048W and YOR065W and YPR191W)" - eccodes: "1.10.2.2" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - kegg.pathway: - "sce00190" @@ -43836,8 +42854,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL045C" - eccodes: "2.7.7.2" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "FMNAT" - kegg.pathway: @@ -43861,8 +42878,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR011W" - eccodes: "1.5.1.39" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "FMNRx" - kegg.reaction: "R05705" @@ -43885,8 +42901,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR011W" - eccodes: "1.5.1.39" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "FMNRx2" - kegg.reaction: "R05706" @@ -43913,8 +42928,7 @@ - "1.1.1.-" - "1.1.1.1" - "1.1.1.284" - - subsystem: - - "Tyrosine metabolism" + - subsystem: "Tyrosine metabolism" - annotation: !!omap - bigg.reaction: "FALDH" - kegg.pathway: @@ -43940,8 +42954,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR388C" - eccodes: "1.2.1.2" - - subsystem: - - "Glyoxylate and dicarboxylate metabolism" + - subsystem: "Glyoxylate and dicarboxylate metabolism" - annotation: !!omap - bigg.reaction: "FDH" - kegg.pathway: @@ -43962,15 +42975,14 @@ - s_0722: -1 - s_1322: 1 - s_1487: -1 - - lower_bound: 0 + - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YGR204W" - eccodes: - "1.5.1.5" - "3.5.4.9" - "6.3.4.3" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "FTHFLi" - kegg.pathway: "sce00670" @@ -44000,8 +43012,7 @@ - "1.5.1.5" - "3.5.4.9" - "6.3.4.3" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "FTHFLmi" - kegg.pathway: "sce00670" @@ -44026,8 +43037,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR345W or YJL155C" - eccodes: "3.1.3.46" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - bigg.reaction: "FBP26" - kegg.pathway: "sce00051" @@ -44048,8 +43058,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR377C" - eccodes: "3.1.3.11" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "FBP" - kegg.pathway: @@ -44076,8 +43085,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL060C" - eccodes: "4.1.2.13" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "FBA" - kegg.pathway: @@ -44104,8 +43112,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL262W" - eccodes: "4.2.1.2" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "FUMm" - kegg.pathway: @@ -44131,8 +43138,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL262W" - eccodes: "4.2.1.2" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "FUM" - kegg.pathway: @@ -44161,8 +43167,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL216W" - eccodes: "1.3.98.1" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "DHORDfum" - kegg.pathway: "sce00240" @@ -44185,8 +43190,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL047C" - eccodes: "1.3.1.6" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "FRDm" - kegg.reaction: "R00408" @@ -44212,8 +43216,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL047C" - eccodes: "1.3.1.6" - - subsystem: - - "Cellular response to anaerobic conditions" + - subsystem: "Cellular response to anaerobic conditions" - annotation: !!omap - bigg.reaction: "FRD" - kegg.reaction: "R00408" @@ -44237,8 +43240,7 @@ - eccodes: - "2.3.2.2" - "3.4.19.13" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "GTMLT" - kegg.pathway: @@ -44261,8 +43263,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR020W" - eccodes: "2.7.1.6" - - subsystem: - - "Galactose metabolism" + - subsystem: "Galactose metabolism" - annotation: !!omap - bigg.reaction: "GALKr" - kegg.pathway: @@ -44286,8 +43287,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR018C" - eccodes: "2.7.7.12" - - subsystem: - - "Galactose metabolism" + - subsystem: "Galactose metabolism" - annotation: !!omap - bigg.reaction: "GALT" - kegg.pathway: @@ -44313,8 +43313,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL101C" - eccodes: "6.3.2.2" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "GLUCYS" - kegg.pathway: @@ -44335,8 +43334,7 @@ - s_1311: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - bigg.reaction: "GGTT" - kegg.reaction: "R07475" @@ -44359,8 +43357,7 @@ - eccodes: - "2.5.1.1" - "2.5.1.10" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "GRTT" - kegg.pathway: @@ -44385,8 +43382,7 @@ - eccodes: - "2.4.1.25" - "3.2.1.33" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "GLCGSD" - kegg.pathway: @@ -44408,8 +43404,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL099W" - eccodes: "3.2.1.3" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "GLCGSDv" - kegg.pathway: "sce00500" @@ -44428,8 +43423,7 @@ - s_0803: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Amino sugar and nucleotide sugar metabolism" + - subsystem: "Amino sugar and nucleotide sugar metabolism" - annotation: !!omap - bigg.reaction: "G6PDA" - metanetx.reaction: "MNXR125024" @@ -44450,8 +43444,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL241C" - eccodes: "1.1.1.49" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "G6PDH2r" - kegg.pathway: @@ -44476,8 +43469,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR196C" - eccodes: "5.3.1.9" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "PGI" - kegg.pathway: @@ -44507,8 +43499,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR300C" - eccodes: "2.7.2.11" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "GLU5K" - kegg.pathway: @@ -44533,8 +43524,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR250W" - eccodes: "4.1.1.15" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "GLUDC" - kegg.pathway: @@ -44564,8 +43554,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL215C" - eccodes: "1.4.1.2" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "GLUDxi" - kegg.pathway: @@ -44594,8 +43583,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAL062W or YOR375C" - eccodes: "1.4.1.4" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "GLUDy" - kegg.pathway: @@ -44618,11 +43606,10 @@ - s_1198: 1 - s_1203: -1 - lower_bound: 0 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YDL171C" - eccodes: "1.4.1.14" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "GLUSx" - kegg.pathway: @@ -44637,6 +43624,7 @@ - sbo: "SBO:0000176" - deltaG: -21.62 - confidence_score: 3 + - rxnNotes: "Only active during nitrogen restriction" - !!omap - id: "r_0473" - name: "glutamate-5-semialdehyde dehydrogenase" @@ -44651,8 +43639,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR323C" - eccodes: "1.2.1.41" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "G5SD" - kegg.pathway: @@ -44677,8 +43664,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YFL060C or YNL334C" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "GLUN" - kegg.reaction: "R00256" @@ -44702,8 +43688,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR035W" - eccodes: "6.3.1.2" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "GLNS" - kegg.pathway: @@ -44730,8 +43715,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL104C" - eccodes: "2.6.1.16" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "GF6PTA" - kegg.pathway: @@ -44759,8 +43743,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR168W" - eccodes: "6.1.1.18" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "GLNTRS" - kegg.pathway: "sce00970" @@ -44784,8 +43767,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL245W" - eccodes: "6.1.1.17" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "GLUTRS" - kegg.pathway: @@ -44811,8 +43793,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL033W" - eccodes: "6.1.1.17" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "GLUTRSm" - kegg.pathway: @@ -44838,8 +43819,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YCL035C and YPL091W) or (YDR098C and YPL091W) or (YDR513W and YPL091W) or (YER174C and YPL091W)" - eccodes: "1.8.1.7" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "GTHOr" - kegg.pathway: "sce00480" @@ -44861,8 +43841,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL059W and YPL091W" - eccodes: "1.8.1.7" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "GTHOm" - kegg.pathway: "sce00480" @@ -44886,8 +43865,7 @@ - eccodes: - "1.11.1.15" - "1.11.1.9" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "GTHPi" - kegg.pathway: "sce00480" @@ -44908,8 +43886,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YPL059W" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "GTHPm" - kegg.reaction: "R00274" @@ -44934,8 +43911,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL049W" - eccodes: "6.3.2.3" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "GTHS" - kegg.pathway: @@ -44960,8 +43936,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR192C or YJL052W or YJR009C" - eccodes: "1.2.1.12" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "GAPD" - kegg.pathway: @@ -44980,17 +43955,16 @@ - id: "r_0487" - name: "glycerol dehydrogenase (NADP-dependent)" - metabolites: !!omap - - s_0765: -1 - - s_0771: 1 - - s_0794: 1 - - s_1207: -1 - - s_1212: 1 + - s_0765: 1 + - s_0771: -1 + - s_0794: -1 + - s_1207: 1 + - s_1212: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOR120W" - eccodes: "1.1.1.156" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - bigg.reaction: "GLYCDy" - kegg.pathway: "sce00561" @@ -45013,8 +43987,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHL032C" - eccodes: "2.7.1.30" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - bigg.reaction: "GLYK" - kegg.pathway: "sce00561" @@ -45035,8 +44008,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER062C or YIL053W" - eccodes: "3.1.3.21" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - bigg.reaction: "G3PT" - kegg.pathway: "sce00561" @@ -45058,8 +44030,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL155C" - eccodes: "1.1.5.3" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - bigg.reaction: "G3PDm" - kegg.pathway: @@ -45084,8 +44055,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL022W or YOL059W" - eccodes: "1.1.1.8" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - bigg.reaction: "G3PD1ir" - kegg.pathway: @@ -45111,8 +44081,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL059W" - eccodes: "1.1.1.8" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - bigg.reaction: "G3PD1irm" - kegg.pathway: @@ -45137,8 +44106,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL110C" - eccodes: "3.1.4.46" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - bigg.reaction: "GPDDA1" - kegg.pathway: "sce00564" @@ -45161,8 +44129,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR408C" - eccodes: "2.1.2.2" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "GARFT" - kegg.pathway: @@ -45185,8 +44152,7 @@ - s_1003: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "GLYAT" - kegg.reaction: "R00371" @@ -45207,14 +44173,13 @@ - s_1205: 1 - s_1488: -1 - lower_bound: 0 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YAL044C and YDR019C and YFL018C and YMR189W" - eccodes: - "1.4.4.2" - "1.8.1.4" - "2.1.2.10" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "GLYCLm" - kegg.pathway: @@ -45232,6 +44197,7 @@ - sbo: "SBO:0000176" - deltaG: 1.69 - confidence_score: 2 + - rxnNotes: "Only active if glycine is nitrogen source, or under nitrogen restriction" - !!omap - id: "r_0502" - name: "glycine hydroxymethyltransferase" @@ -45245,8 +44211,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR058C" - eccodes: "2.1.2.1" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "GHMT2r" - kegg.pathway: @@ -45277,8 +44242,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR263W" - eccodes: "2.1.2.1" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "GHMT2rm" - kegg.pathway: @@ -45314,8 +44278,7 @@ - "1.4.4.2" - "1.8.1.4" - "2.1.2.10" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "GCC2am" - kegg.pathway: @@ -45352,8 +44315,7 @@ - "1.8.1.4" - "2.1.2.10" - "2.3.1.61" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "GCC2cm" - kegg.pathway: @@ -45390,8 +44352,7 @@ - "1.4.4.2" - "1.8.1.4" - "2.1.2.10" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "GCCam" - kegg.pathway: @@ -45423,14 +44384,13 @@ - s_1410: -1 - s_1488: -1 - lower_bound: 0 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YAL044C and YDR019C and YFL018C and YMR189W" - eccodes: - "1.4.4.2" - "1.8.1.4" - "2.1.2.10" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "GCCbim" - kegg.pathway: @@ -45450,7 +44410,7 @@ - sbo: "SBO:0000176" - deltaG: 10000000 - confidence_score: 2 - - rxnNotes: "MetaNetX ID curated (PR #220) | KEGG ID curated (PR #220) | model.S(606,396) curated (PR #222)" + - rxnNotes: "Only active if glycine is nitrogen source, or under nitrogen restriction" - !!omap - id: "r_0508" - name: "glycine-cleavage complex (lipoylprotein)" @@ -45467,8 +44427,7 @@ - "1.4.4.2" - "1.8.1.4" - "2.1.2.10" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "GCCcm" - kegg.pathway: @@ -45498,14 +44457,13 @@ - s_1409: -1 - s_1488: -1 - lower_bound: 0 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YAL044C and YDR019C and YFL018C and YMR189W" - eccodes: - "1.4.4.2" - "1.8.1.4" - "2.1.2.10" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "GCC2bim" - kegg.pathway: @@ -45523,6 +44481,7 @@ - sbo: "SBO:0000176" - deltaG: -3.54 - confidence_score: 2 + - rxnNotes: "Only active if glycine is nitrogen source, or under nitrogen restriction" - !!omap - id: "r_0510" - name: "glycogen (starch) synthase" @@ -45537,8 +44496,7 @@ - eccodes: - "2.4.1.11" - "2.4.1.186" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - kegg.pathway: "sce00500" - metanetx.reaction: "MNXR143136" @@ -45558,8 +44516,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR160W" - eccodes: "2.4.1.1" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "GLCP" - kegg.pathway: @@ -45583,8 +44540,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR121C or YPR081C" - eccodes: "6.1.1.14" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "GLYTRS" - kegg.pathway: "sce00970" @@ -45611,8 +44567,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR217W" - eccodes: "6.3.5.2" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "GMPS2" - kegg.pathway: "sce00230" @@ -45634,8 +44589,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR281W" - eccodes: "3.5.1.89" - - subsystem: - - "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" + - subsystem: "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" - annotation: !!omap - kegg.pathway: "sce00563" - kegg.reaction: "R05917" @@ -45657,8 +44611,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL052C and YJR013W" - eccodes: "2.4.1.-" - - subsystem: - - "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" + - subsystem: "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" - annotation: !!omap - kegg.pathway: "sce00563" - pubmed: "11102867" @@ -45676,8 +44629,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL165C" - eccodes: "2.-.-.-" - - subsystem: - - "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" + - subsystem: "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" - annotation: !!omap - kegg.pathway: "sce00563" - pubmed: "11102867" @@ -45696,8 +44648,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR004C" - eccodes: "2.4.1.-" - - subsystem: - - "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" + - subsystem: "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" - annotation: !!omap - kegg.pathway: "sce00563" - pubmed: "15623507" @@ -45715,8 +44666,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL142C" - eccodes: "2.4.1.-" - - subsystem: - - "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" + - subsystem: "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" - annotation: !!omap - kegg.pathway: "sce00563" - pubmed: "11102867" @@ -45735,8 +44685,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR302W or YLL031C" - eccodes: "2.-.-.-" - - subsystem: - - "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" + - subsystem: "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" - annotation: !!omap - kegg.pathway: "sce00563" - pubmed: "10793139" @@ -45756,8 +44705,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR267C" - eccodes: "3.5.4.16" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "GTPCI" - kegg.pathway: "sce00790" @@ -45780,8 +44728,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL033C" - eccodes: "3.5.4.25" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "GTPCII2" - kegg.pathway: @@ -45806,8 +44753,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL238C" - eccodes: "3.5.4.3" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "GUAD" - kegg.pathway: "sce00230" @@ -45829,8 +44775,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR399W" - eccodes: "2.4.2.8" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "GUAPRT" - kegg.pathway: @@ -45853,8 +44798,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR454C" - eccodes: "2.7.4.8" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "GK1" - kegg.pathway: "sce00230" @@ -45875,8 +44819,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR454C" - eccodes: "2.7.4.8" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "GK2" - kegg.pathway: "sce00230" @@ -45898,8 +44841,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER141W or (YDR376W and YPL252C)" - eccodes: "1.18.1.6" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "HEMEOMOm" - metanetx.reaction: "MNXR100595" @@ -45920,8 +44862,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL172C" - eccodes: "2.5.1.-" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "HEMEOSm" - kegg.pathway: @@ -45952,8 +44893,7 @@ - "2.1.1.201" - "2.1.1.64" - "2.7.-.-" - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00130" @@ -45974,8 +44914,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR446W or YFR053C or YGL253W" - eccodes: "2.7.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "HEX7" - kegg.pathway: @@ -46007,8 +44946,7 @@ - eccodes: - "2.7.1.1" - "2.7.1.2" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "HEX1" - kegg.pathway: @@ -46039,8 +44977,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR446W or YFR053C or YGL253W" - eccodes: "2.7.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "HEX4" - kegg.pathway: @@ -46074,8 +45011,7 @@ - "1.1.1.23" - "3.5.4.19" - "3.6.1.31" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - bigg.reaction: "HISTD" - kegg.pathway: @@ -46099,8 +45035,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR025C" - eccodes: "3.1.3.15" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - bigg.reaction: "HISTP" - kegg.pathway: @@ -46124,8 +45059,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL116W" - eccodes: "2.6.1.9" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - bigg.reaction: "HSTPT" - kegg.pathway: @@ -46155,8 +45089,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR033C" - eccodes: "6.1.1.21" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "HISTRS" - kegg.pathway: "sce00970" @@ -46180,8 +45113,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR033C" - eccodes: "6.1.1.21" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "HISTRSm" - kegg.pathway: "sce00970" @@ -46204,8 +45136,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR034C" - eccodes: "2.1.1.-" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - bigg.reaction: "ARMT" - kegg.reaction: "R01159" @@ -46226,8 +45157,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL200C or YDR234W" - eccodes: "4.2.1.36" - - subsystem: - - "Lysine metabolism" + - subsystem: "Lysine metabolism" - annotation: !!omap - bigg.reaction: "HACNHm" - kegg.pathway: @@ -46255,8 +45185,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL131W or YDL182W" - eccodes: "2.3.3.14" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - kegg.pathway: - "sce00300" @@ -46283,8 +45212,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL062C or YPL273W" - eccodes: "2.1.1.10" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "HCYSMT" - kegg.pathway: @@ -46309,8 +45237,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL094C" - eccodes: "1.1.1.87" - - subsystem: - - "Lysine metabolism" + - subsystem: "Lysine metabolism" - annotation: !!omap - kegg.pathway: - "sce00300" @@ -46337,8 +45264,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR139C" - eccodes: "1.1.1.3" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "HSDxi" - kegg.pathway: @@ -46369,8 +45295,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR139C" - eccodes: "1.1.1.3" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "HSDy" - kegg.pathway: @@ -46399,8 +45324,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR025W" - eccodes: "2.7.1.39" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "HSK" - kegg.pathway: @@ -46425,8 +45349,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL277W" - eccodes: "2.3.1.31" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "HSERTA" - kegg.pathway: @@ -46451,8 +45374,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YDR453C and YGR209C) or (YDR453C and YLR043C)" - eccodes: "1.11.1.15" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "THIORDXi" - metanetx.reaction: "MNXR104815" @@ -46474,8 +45396,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL064C and YCR083W" - eccodes: "1.11.1.15" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "THIORDXm" - metanetx.reaction: "MNXR104815" @@ -46497,8 +45418,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YGR209C and YLR109W) or (YLR043C and YLR109W)" - eccodes: "1.11.1.15" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "THIORDXp" - kegg.pathway: "sce04122" @@ -46521,8 +45441,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR272W" - eccodes: "3.1.2.6" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "GLYOX" - kegg.pathway: "sce00620" @@ -46544,8 +45463,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR040W" - eccodes: "3.1.2.6" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "GLYOXm" - kegg.pathway: "sce00620" @@ -46566,8 +45484,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR041C" - eccodes: "2.5.1.39" - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - bigg.reaction: "HBZOPT6m" - kegg.pathway: @@ -46593,8 +45510,7 @@ - eccodes: - "2.5.1.3" - "2.7.1.50" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "HETZK" - kegg.pathway: "sce00730" @@ -46615,8 +45531,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL205C" - eccodes: "2.5.1.61" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "HMBS" - kegg.pathway: @@ -46641,8 +45556,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR450W or YML075C" - eccodes: "1.1.1.34" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "HMGCOAR" - kegg.pathway: @@ -46669,8 +45583,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML126C" - eccodes: "2.3.3.10" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "HMGCOASm" - kegg.pathway: @@ -46700,8 +45613,7 @@ - eccodes: - "2.7.1.49" - "2.7.4.7" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "HMPK1" - kegg.pathway: "sce00730" @@ -46722,8 +45634,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR399W" - eccodes: "2.4.2.8" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "HXPRT" - kegg.pathway: @@ -46750,8 +45661,7 @@ - eccodes: - "2.4.2.-" - "4.1.3.-" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - bigg.reaction: "IG3PS" - kegg.pathway: @@ -46774,8 +45684,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR202W" - eccodes: "4.2.1.19" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - bigg.reaction: "IGPDH" - kegg.pathway: @@ -46801,8 +45710,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR216W or YLR432W or YML056C" - eccodes: "1.1.1.205" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "IMPD" - kegg.pathway: @@ -46829,8 +45737,7 @@ - eccodes: - "4.1.1.48" - "4.1.3.27" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "IGPS" - kegg.pathway: @@ -46860,8 +45767,7 @@ - "4.1.1.1" - "4.1.1.43" - "4.1.1.74" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "INDPYRD" - kegg.pathway: @@ -46886,8 +45792,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR011C" - eccodes: "3.6.1.1" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - bigg.reaction: "PPA" - kegg.pathway: "sce00190" @@ -46909,8 +45814,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR267W" - eccodes: "3.6.1.1" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - bigg.reaction: "PPAm" - kegg.pathway: "sce00190" @@ -46933,8 +45837,7 @@ - eccodes: - "2.1.2.3" - "3.5.4.10" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "IMPC" - kegg.pathway: @@ -46960,8 +45863,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR315C" - eccodes: "2.7.1.158" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -46986,8 +45888,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR173C" - eccodes: "2.7.1.151" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -47013,8 +45914,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR173C" - eccodes: "2.7.1.151" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -47040,8 +45940,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR173C" - eccodes: "2.7.1.151" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -47067,8 +45966,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR173C" - eccodes: "2.7.1.151" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -47093,8 +45991,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47115,8 +46012,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47137,8 +46033,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47159,8 +46054,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47181,8 +46075,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47203,8 +46096,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47225,8 +46117,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47247,8 +46138,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47269,8 +46159,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47291,8 +46180,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47313,8 +46201,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47335,8 +46222,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47357,8 +46243,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47379,8 +46264,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47401,8 +46285,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47423,8 +46306,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47445,8 +46327,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47467,8 +46348,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47489,8 +46369,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47511,8 +46390,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47534,8 +46412,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47558,8 +46435,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47582,8 +46458,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47606,8 +46481,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47630,8 +46504,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47654,8 +46527,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47678,8 +46550,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47702,8 +46573,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47726,8 +46596,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47750,8 +46619,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47773,8 +46641,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47795,8 +46662,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47817,8 +46683,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47839,8 +46704,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47861,8 +46725,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47883,8 +46746,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47905,8 +46767,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47927,8 +46788,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47949,8 +46809,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47971,8 +46830,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -47993,8 +46851,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48015,8 +46872,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48037,8 +46893,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48059,8 +46914,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48081,8 +46935,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48103,8 +46956,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48125,8 +46977,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48147,8 +46998,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48169,8 +47019,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48191,8 +47040,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48214,8 +47062,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48238,8 +47085,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48262,8 +47108,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48286,8 +47131,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48310,8 +47154,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48334,8 +47177,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48358,8 +47200,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48382,8 +47223,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48406,8 +47246,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48430,8 +47269,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER019W" - eccodes: "3.1.4.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - pubmed: @@ -48454,8 +47292,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ACHLE1" - metanetx.reaction: "MNXR95262" @@ -48476,8 +47313,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - - subsystem: - - "Complex alcohol metabolism" + - subsystem: "Complex alcohol metabolism" - annotation: !!omap - bigg.reaction: "ACHLE2" - metanetx.reaction: "MNXR95263" @@ -48498,8 +47334,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL037C and YOR136W" - eccodes: "1.1.1.41" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "ICDHxm" - kegg.pathway: @@ -48528,8 +47363,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR174W" - eccodes: "1.1.1.42" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "ICDHyr" - kegg.pathway: @@ -48560,8 +47394,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL009W" - eccodes: "1.1.1.42" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "ICDHyp" - kegg.pathway: @@ -48592,8 +47425,7 @@ - eccodes: - "4.1.3.1" - "4.1.3.30" - - subsystem: - - "Glyoxylate and dicarboxylate metabolism" + - subsystem: "Glyoxylate and dicarboxylate metabolism" - annotation: !!omap - bigg.reaction: "ICL" - kegg.pathway: @@ -48617,8 +47449,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR148W" - eccodes: "2.6.1.42" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "ILETA" - kegg.pathway: @@ -48648,8 +47479,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR208W" - eccodes: "2.6.1.42" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "ILETAm" - kegg.pathway: @@ -48681,8 +47511,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL076C" - eccodes: "6.1.1.5" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "ILETRS" - kegg.pathway: "sce00970" @@ -48706,8 +47535,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL040C" - eccodes: "6.1.1.5" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "ILETRSm" - kegg.pathway: "sce00970" @@ -48727,8 +47555,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL117C" - eccodes: "5.3.3.2" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "IPDDI" - kegg.pathway: @@ -48754,8 +47581,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR244C and YOR142W" - eccodes: "6.2.1.5" - - subsystem: - - "C5-branched dibasic acid metabolism" + - subsystem: "C5-branched dibasic acid metabolism" - annotation: !!omap - bigg.reaction: "ITCOALm" - kegg.pathway: @@ -48783,8 +47609,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR355C" - eccodes: "1.1.1.86" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "KARA2im" - kegg.pathway: @@ -48812,8 +47637,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR231C" - eccodes: "3.7.1.3" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "KYN" - kegg.pathway: "sce00380" @@ -48838,8 +47662,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL098W" - eccodes: "1.14.13.9" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "KYN3OX" - kegg.pathway: "sce00380" @@ -48863,8 +47686,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR037W" - eccodes: "1.2.1.88" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "PHCDm" - kegg.pathway: @@ -48889,8 +47711,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR037W" - eccodes: "1.2.1.88" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "4HGLSDm" - kegg.pathway: @@ -48913,8 +47734,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR089C" - eccodes: "2.6.1.2" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "ALATA_Lm" - kegg.pathway: @@ -48939,8 +47759,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL046C" - eccodes: "4.1.2.48" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "THRA2" - kegg.pathway: @@ -48967,8 +47786,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR226C" - eccodes: "1.1.1.381" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "ATHRDHr" - kegg.pathway: @@ -48999,8 +47817,7 @@ - "1.2.1.31" - "1.2.1.95" - "2.7.8.7" - - subsystem: - - "Lysine metabolism" + - subsystem: "Lysine metabolism" - annotation: !!omap - bigg.reaction: "AASAD1" - kegg.pathway: @@ -49026,8 +47843,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR321W" - eccodes: "3.5.1.1" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "ASNN" - kegg.pathway: @@ -49051,8 +47867,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR155C or YLR157C or YLR158C or YLR160C" - eccodes: "3.5.1.1" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "ASNNe" - kegg.reaction: "R00485" @@ -49073,8 +47888,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR027C" - eccodes: "2.6.1.1" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "EHGLAT" - kegg.pathway: @@ -49107,8 +47921,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL106W" - eccodes: "2.6.1.1" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "EHGLATm" - kegg.pathway: @@ -49141,8 +47954,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR027C" - eccodes: "2.6.1.1" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "EHGLATp" - kegg.pathway: @@ -49176,8 +47988,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER023W" - eccodes: "1.5.1.2" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - kegg.reaction: "R03293" - metanetx.reaction: "MNXR100699" @@ -49201,8 +48012,7 @@ - "1.1.1.21" - "1.1.1.265" - "1.1.1.283" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "LALDO3" - kegg.pathway: @@ -49229,8 +48039,7 @@ - eccodes: - "4.3.1.17" - "4.3.1.19" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "SERD_L" - kegg.pathway: @@ -49260,8 +48069,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR226C" - eccodes: "1.1.1.381" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "LSERDHr" - kegg.pathway: @@ -49286,8 +48094,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR159W" - eccodes: "1.1.1.14" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - bigg.reaction: "SBTD_L" - kegg.pathway: @@ -49310,8 +48117,7 @@ - eccodes: - "4.3.1.17" - "4.3.1.19" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "THRD_L" - kegg.pathway: @@ -49339,8 +48145,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER086W" - eccodes: "4.3.1.19" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "THRD_Lm" - kegg.pathway: @@ -49367,8 +48172,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR078W" - eccodes: "1.13.11.52" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "TRPO2" - kegg.pathway: "sce00380" @@ -49390,8 +48194,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR403W" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "TYRNFT" - metanetx.reaction: "MNXR104994" @@ -49412,8 +48215,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOL151W" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "LCADi" - kegg.reaction: "R01446" @@ -49433,8 +48235,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML004C" - eccodes: "4.4.1.5" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "LGTHL" - kegg.pathway: "sce00620" @@ -49453,8 +48254,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR072W" - eccodes: "5.4.99.7" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "LNSTLS" - kegg.pathway: @@ -49478,8 +48278,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR148W" - eccodes: "2.6.1.42" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "LEUTA" - kegg.pathway: @@ -49509,8 +48308,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR208W" - eccodes: "2.6.1.42" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "LEUTAm" - kegg.pathway: @@ -49542,8 +48340,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL160W" - eccodes: "6.1.1.4" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "LEUTRS" - kegg.pathway: "sce00970" @@ -49567,8 +48364,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR382C" - eccodes: "6.1.1.4" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "LEUTRSm" - kegg.pathway: "sce00970" @@ -49589,8 +48385,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL045W" - eccodes: "3.3.2.6" - - subsystem: - - "Arachidonic acid metabolism" + - subsystem: "Arachidonic acid metabolism" - annotation: !!omap - pubmed: "11601994" - sbo: "SBO:0000176" @@ -49607,8 +48402,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL045W" - eccodes: "3.3.2.6" - - subsystem: - - "Arachidonic acid metabolism" + - subsystem: "Arachidonic acid metabolism" - annotation: !!omap - pubmed: "11601994" - sbo: "SBO:0000176" @@ -49625,8 +48419,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL045W" - eccodes: "3.3.2.6" - - subsystem: - - "Arachidonic acid metabolism" + - subsystem: "Arachidonic acid metabolism" - annotation: !!omap - pubmed: "11601994" - sbo: "SBO:0000176" @@ -49643,8 +48436,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL045W" - eccodes: "3.3.2.6" - - subsystem: - - "Arachidonic acid metabolism" + - subsystem: "Arachidonic acid metabolism" - annotation: !!omap - pubmed: "11601994" - sbo: "SBO:0000176" @@ -49661,8 +48453,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL045W" - eccodes: "3.3.2.6" - - subsystem: - - "Arachidonic acid metabolism" + - subsystem: "Arachidonic acid metabolism" - annotation: !!omap - bigg.reaction: "LTA4H" - kegg.reaction: "R03057" @@ -49682,8 +48473,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL045W" - eccodes: "3.3.2.6" - - subsystem: - - "Arachidonic acid metabolism" + - subsystem: "Arachidonic acid metabolism" - annotation: !!omap - kegg.reaction: "R03057" - metanetx.reaction: "MNXR107919" @@ -49705,8 +48495,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR037W" - eccodes: "6.1.1.6" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "LYSTRS" - kegg.pathway: "sce00970" @@ -49730,8 +48519,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL073W" - eccodes: "6.1.1.6" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "LYSTRSm" - kegg.pathway: "sce00970" @@ -49754,8 +48542,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL085W" - eccodes: "1.1.1.37" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "MDHm" - kegg.pathway: @@ -49785,8 +48572,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL126C" - eccodes: "1.1.1.37" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "MDH" - kegg.pathway: @@ -49816,8 +48602,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL078C" - eccodes: "1.1.1.37" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "MDHp" - kegg.pathway: @@ -49848,8 +48633,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIR031C or YNL117W" - eccodes: "2.3.3.9" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "MALS" - kegg.pathway: @@ -49876,8 +48660,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL117W" - eccodes: "2.3.3.9" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "MALSp" - kegg.pathway: @@ -49904,8 +48687,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL029C" - eccodes: "1.1.1.38" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "ME1m" - kegg.pathway: @@ -49933,8 +48715,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL029C" - eccodes: "1.1.1.38" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "ME2m" - kegg.pathway: @@ -49955,14 +48736,14 @@ - metabolites: !!omap - s_0465: 1 - s_0532: 1 + - s_0799: -1 - s_1104: -1 - s_1845: -1 - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKL192C and YOR221C" - eccodes: "2.3.1.39" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "MCOATAm" - kegg.pathway: @@ -49989,8 +48770,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL055C" - eccodes: "2.7.7.13" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - bigg.reaction: "MAN1PT" - kegg.pathway: @@ -50012,8 +48792,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER003C" - eccodes: "5.3.1.8" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - bigg.reaction: "MAN6PI" - kegg.pathway: @@ -50042,8 +48821,7 @@ - "1.5.1.5" - "3.5.4.9" - "6.3.4.3" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "MTHFCm" - kegg.pathway: "sce00670" @@ -50067,8 +48845,7 @@ - "1.5.1.5" - "3.5.4.9" - "6.3.4.3" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "MTHFC" - kegg.pathway: "sce00670" @@ -50091,8 +48868,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR502C or YLR180W" - eccodes: "2.5.1.6" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "METAT" - kegg.pathway: @@ -50117,8 +48893,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER091C" - eccodes: "2.1.1.14" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "METS" - kegg.pathway: @@ -50146,8 +48921,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL013W" - eccodes: "2.1.2.9" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "FMETTRSm" - kegg.pathway: @@ -50173,8 +48947,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR264C" - eccodes: "6.1.1.10" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "METTRS" - kegg.pathway: @@ -50200,8 +48973,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR171C" - eccodes: "6.1.1.10" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "METTRSm" - kegg.pathway: @@ -50225,8 +48997,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR080W" - eccodes: "1.5.1.15" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "MTHFD2i" - kegg.pathway: "sce00670" @@ -50239,19 +49010,18 @@ - id: "r_0732" - name: "methylenetetrahydrofolate dehydrogenase (NADP)" - metabolites: !!omap - - s_0304: 1 - - s_0306: -1 - - s_1207: -1 - - s_1212: 1 - - lower_bound: -1000 + - s_0304: -1 + - s_0306: 1 + - s_1207: 1 + - s_1212: -1 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGR204W" - eccodes: - "1.5.1.5" - "3.5.4.9" - "6.3.4.3" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "MTHFD" - kegg.pathway: "sce00670" @@ -50264,19 +49034,18 @@ - id: "r_0733" - name: "methylenetetrahydrofolate dehydrogenase (NADP)" - metabolites: !!omap - - s_0305: 1 - - s_0307: -1 - - s_1210: -1 - - s_1214: 1 - - lower_bound: -1000 + - s_0305: -1 + - s_0307: 1 + - s_1210: 1 + - s_1214: -1 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR084W" - eccodes: - "1.5.1.5" - "3.5.4.9" - "6.3.4.3" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "MTHFDm" - kegg.pathway: "sce00670" @@ -50300,8 +49069,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR006C" - eccodes: "4.1.3.30" - - subsystem: - - "Propanoate metabolism" + - subsystem: "Propanoate metabolism" - annotation: !!omap - bigg.reaction: "MCITL2m" - kegg.pathway: @@ -50327,8 +49095,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR208W" - eccodes: "2.7.1.36" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "MEVK1" - kegg.pathway: @@ -50354,8 +49121,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR208W" - eccodes: "2.7.1.36" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "MEVK2" - kegg.pathway: @@ -50380,8 +49146,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR208W" - eccodes: "2.7.1.36" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "MEVK3" - kegg.pathway: @@ -50406,8 +49171,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR208W" - eccodes: "2.7.1.36" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "MEVK4" - kegg.pathway: @@ -50433,8 +49197,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR043W" - eccodes: "4.1.1.33" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "DPMVD" - kegg.pathway: @@ -50461,8 +49224,7 @@ - eccodes: - "2.-.-.-" - "2.4.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - metanetx.reaction: "MNXR126697" - pubmed: @@ -50487,8 +49249,7 @@ - eccodes: - "2.-.-.-" - "2.4.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "12954640" @@ -50512,8 +49273,7 @@ - eccodes: - "2.-.-.-" - "2.4.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "12954640" @@ -50537,8 +49297,7 @@ - eccodes: - "2.-.-.-" - "2.4.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "12954640" @@ -50562,8 +49321,7 @@ - eccodes: - "2.-.-.-" - "2.4.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "12954640" @@ -50587,8 +49345,7 @@ - eccodes: - "2.-.-.-" - "2.4.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "12954640" @@ -50612,8 +49369,7 @@ - eccodes: - "2.-.-.-" - "2.4.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "12954640" @@ -50637,8 +49393,7 @@ - eccodes: - "2.-.-.-" - "2.4.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "12954640" @@ -50662,8 +49417,7 @@ - eccodes: - "2.-.-.-" - "2.4.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "12954640" @@ -50687,8 +49441,7 @@ - eccodes: - "2.-.-.-" - "2.4.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "12954640" @@ -50709,8 +49462,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR287W or YHR046C" - eccodes: "3.1.3.25" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - bigg.reaction: "MI1PP" - kegg.pathway: @@ -50732,8 +49484,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL153C" - eccodes: "5.5.1.4" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - bigg.reaction: "MI1PS" - kegg.pathway: @@ -50759,8 +49510,7 @@ - eccodes: - "1.2.1.38" - "2.7.2.8" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "AGPRim" - kegg.pathway: @@ -50787,8 +49537,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFL017C" - eccodes: "2.3.1.4" - - subsystem: - - "Amino sugar and nucleotide sugar metabolism" + - subsystem: "Amino sugar and nucleotide sugar metabolism" - annotation: !!omap - bigg.reaction: "ACGAM6PS" - kegg.pathway: "sce00520" @@ -50814,8 +49563,7 @@ - eccodes: - "2.3.1.1" - "2.3.1.35" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "ACGSm" - kegg.pathway: @@ -50842,8 +49590,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR428C" - eccodes: "3.5.1.9" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "FKYNH" - kegg.pathway: @@ -50868,8 +49615,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR402C and YDR403W" - eccodes: "1.14.14.-" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -50893,8 +49639,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL067W" - eccodes: "3.6.1.22" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NADDPp" - kegg.pathway: @@ -50920,8 +49665,7 @@ - eccodes: - "2.7.1.23" - "2.7.1.86" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NADK" - kegg.pathway: "sce00760" @@ -50946,8 +49690,7 @@ - eccodes: - "2.7.1.23" - "2.7.1.86" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NADKm" - kegg.pathway: "sce00760" @@ -50970,8 +49713,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL042C or YDR191W or YOL068C or YOR025W or YPL015C" - eccodes: "3.5.1.-" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - kegg.pathway: - "sce00760" @@ -50999,8 +49741,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR074W" - eccodes: "6.3.5.1" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NADS2" - kegg.pathway: "sce00760" @@ -51027,8 +49768,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR074W" - eccodes: "6.3.5.1" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - kegg.pathway: "sce00760" - kegg.reaction: "R00257" @@ -51050,8 +49790,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL085W or YMR145C" - eccodes: "1.6.5.9" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - bigg.reaction: "NADH2_u6cm" - metanetx.reaction: "MNXR101868" @@ -51074,8 +49813,7 @@ - eccodes: - "2.7.1.23" - "2.7.1.86" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - kegg.pathway: "sce00760" - kegg.reaction: "R00105" @@ -51099,8 +49837,7 @@ - eccodes: - "2.7.1.23" - "2.7.1.86" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - kegg.pathway: "sce00760" - kegg.reaction: "R00105" @@ -51122,8 +49859,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML120C" - eccodes: "1.6.5.9" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - bigg.reaction: "NADH2_u6m" - metanetx.reaction: "MNXR101869" @@ -51137,7 +49873,7 @@ - s_0394: 1 - s_0434: -1 - s_0633: 1 - - s_0794: -1 + - s_0803: -1 - s_1219: -1 - s_1222: 1 - s_1322: 1 @@ -51146,8 +49882,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR209C" - eccodes: "6.3.4.21" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NAPRT" - kegg.pathway: "sce00760" @@ -51163,7 +49898,7 @@ - s_0397: 1 - s_0437: -1 - s_0636: 1 - - s_0799: -1 + - s_0807: -1 - s_1221: -1 - s_1223: 1 - s_1326: 1 @@ -51172,8 +49907,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR209C" - eccodes: "6.3.4.21" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NAPRTm" - kegg.pathway: "sce00760" @@ -51194,8 +49928,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL037C" - eccodes: "3.5.1.19" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NNAM" - kegg.pathway: @@ -51218,8 +49951,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR285W" - eccodes: "2.1.1.-" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NNMT" - kegg.reaction: "R01269" @@ -51243,8 +49975,7 @@ - eccodes: - "2.7.7.1" - "2.7.7.18" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NMNAT" - kegg.pathway: "sce00760" @@ -51269,8 +50000,7 @@ - eccodes: - "2.7.7.1" - "2.7.7.18" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NMNATn" - kegg.pathway: "sce00760" @@ -51295,8 +50025,7 @@ - eccodes: - "2.7.7.1" - "2.7.7.18" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NNATr" - kegg.pathway: "sce00760" @@ -51320,8 +50049,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR047C" - eccodes: "2.4.2.19" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NNDPR" - kegg.pathway: "sce00760" @@ -51344,8 +50072,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR047C" - eccodes: "2.4.2.19" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "NNDPRm" - kegg.pathway: "sce00760" @@ -51367,8 +50094,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER005W" - eccodes: "3.6.1.5" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NDP1" - kegg.pathway: @@ -51393,8 +50119,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER005W" - eccodes: "3.6.1.5" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NDP3" - kegg.pathway: @@ -51419,8 +50144,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER005W" - eccodes: "3.6.1.5" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NDP7" - kegg.pathway: @@ -51445,8 +50169,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL042W" - eccodes: "3.6.1.42" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NDP7g" - kegg.reaction: "R00155" @@ -51467,8 +50190,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER005W" - eccodes: "3.6.1.5" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "CDPPH" - kegg.pathway: @@ -51492,8 +50214,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER005W" - eccodes: "3.6.1.5" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "IDPA" - kegg.pathway: @@ -51516,8 +50237,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NDPK3" - kegg.pathway: @@ -51542,8 +50262,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NDPK8" - kegg.pathway: @@ -51568,8 +50287,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NDPK7" - kegg.pathway: @@ -51594,8 +50312,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NDPK5" - kegg.pathway: @@ -51620,8 +50337,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NDPK4" - kegg.pathway: @@ -51646,8 +50362,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NDPK1" - kegg.pathway: @@ -51672,8 +50387,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NDPK9" - kegg.pathway: @@ -51698,8 +50412,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NDPK10" - kegg.pathway: @@ -51724,8 +50437,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NDPK6" - kegg.pathway: @@ -51751,8 +50463,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAL035W or YLL001W or YER005W" - eccodes: "3.6.1.5" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTP3" - kegg.pathway: @@ -51777,8 +50488,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER005W" - eccodes: "3.6.1.5" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NTP7" - kegg.pathway: @@ -51803,8 +50513,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER005W" - eccodes: "3.6.1.5" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NTP5" - kegg.pathway: @@ -51826,10 +50535,9 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "YER005W" + - gene_reaction_rule: "YJR069C" - eccodes: "3.6.1.5" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTP10" - kegg.pathway: @@ -51853,8 +50561,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL042W" - eccodes: "3.6.1.42" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NDP3g" - kegg.reaction: "R00328" @@ -51874,8 +50581,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NDPK2" - kegg.pathway: @@ -51903,8 +50609,7 @@ - eccodes: - "2.5.1.47" - "2.5.1.49" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "AHSERL" - kegg.pathway: @@ -51934,8 +50639,7 @@ - eccodes: - "2.5.1.47" - "2.5.1.49" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "AHSERL2" - kegg.pathway: @@ -51965,8 +50669,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL058W or YML082W or YAL012W" - eccodes: "4.4.1.1" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "SHSL1" - kegg.pathway: @@ -51994,8 +50697,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL088W" - eccodes: "2.1.3.3" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "OCBT" - kegg.pathway: @@ -52020,8 +50722,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL184W" - eccodes: "4.1.1.17" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "ORNDC" - kegg.pathway: @@ -52048,8 +50749,7 @@ - eccodes: - "2.3.1.1" - "2.3.1.35" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "ORNTACim" - kegg.pathway: @@ -52075,8 +50775,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR438W" - eccodes: "2.6.1.13" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "ORNTA" - kegg.pathway: @@ -52100,8 +50799,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML106W or YMR271C" - eccodes: "2.4.2.10" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "ORPT" - kegg.pathway: "sce00240" @@ -52122,8 +50820,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL021W" - eccodes: "4.1.1.23" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "OMPDC" - kegg.pathway: "sce00240" @@ -52147,8 +50844,7 @@ - "1.2.4.2" - "1.8.1.4" - "2.3.1.61" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "AKGDbm" - kegg.pathway: @@ -52186,8 +50882,7 @@ - "1.2.4.2" - "1.8.1.4" - "2.3.1.61" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "AKGDam" - kegg.pathway: @@ -52222,8 +50917,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR277C" - eccodes: "2.7.7.3" - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "PTPATi" - kegg.pathway: "sce00770" @@ -52246,8 +50940,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR531W" - eccodes: "2.7.1.33" - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "PNTK" - kegg.pathway: "sce00770" @@ -52271,8 +50964,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL145C" - eccodes: "6.3.2.1" - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "PANTS" - kegg.pathway: @@ -52297,8 +50989,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR019C" - eccodes: "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -52322,8 +51013,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR019C" - eccodes: "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - bigg.reaction: "PTE11x" - kegg.pathway: @@ -52348,8 +51038,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR019C" - eccodes: "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - bigg.reaction: "PTE2x" - kegg.pathway: @@ -52375,8 +51064,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR019C" - eccodes: "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - bigg.reaction: "PTE7x" - kegg.pathway: @@ -52401,8 +51089,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR019C" - eccodes: "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - bigg.reaction: "PTE8x" - kegg.pathway: @@ -52428,8 +51115,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR019C" - eccodes: "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - bigg.reaction: "PTE9x" - kegg.pathway: @@ -52455,8 +51141,7 @@ - eccodes: - "2.6.1.39" - "2.6.1.57" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "PHETA1" - kegg.pathway: @@ -52494,8 +51179,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFL022C and YLR060W" - eccodes: "6.1.1.20" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "PHETRS" - kegg.pathway: "sce00970" @@ -52519,8 +51203,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR047W" - eccodes: "6.1.1.20" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "PHETRSm" - kegg.pathway: "sce00970" @@ -52542,8 +51225,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR380W" - eccodes: "4.1.1.43" - - subsystem: - - "Phenylalanine metabolism" + - subsystem: "Phenylalanine metabolism" - annotation: !!omap - bigg.reaction: "PPYRDC" - kegg.pathway: "sce00360" @@ -52570,8 +51252,7 @@ - eccodes: - "6.3.3.1" - "6.3.4.13" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PRAIS" - kegg.pathway: @@ -52594,8 +51275,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL058W" - eccodes: "5.4.2.3" - - subsystem: - - "Amino sugar and nucleotide sugar metabolism" + - subsystem: "Amino sugar and nucleotide sugar metabolism" - annotation: !!omap - kegg.pathway: - "sce00520" @@ -52620,8 +51300,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YGR209C and YPR167C) or (YLR043C and YPR167C)" - eccodes: "1.8.4.8" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - bigg.reaction: "PAPSR" - kegg.pathway: "sce00920" @@ -52644,8 +51323,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR097W" - eccodes: "4.1.1.49" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "PPCK" - kegg.pathway: @@ -52673,8 +51351,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR007W" - eccodes: "2.7.7.14" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - bigg.reaction: "PETHCT" - kegg.pathway: @@ -52698,8 +51375,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR240C and YMR205C" - eccodes: "2.7.1.11" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "PFK" - kegg.pathway: @@ -52718,38 +51394,6 @@ - sbo: "SBO:0000176" - deltaG: -16.73 - confidence_score: 3 - - !!omap - - id: "r_0887" - - name: "phosphofructokinase (s7p)" - - metabolites: !!omap - - s_0394: 1 - - s_0434: -1 - - s_0794: 1 - - s_1426: 1 - - s_1427: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "YGR240C and YMR205C" - - eccodes: "2.7.1.11" - - subsystem: - - "Glycolysis / gluconeogenesis" - - annotation: !!omap - - bigg.reaction: "PFK_3" - - kegg.pathway: - - "sce00010" - - "sce00030" - - "sce00051" - - "sce00052" - - "sce01110" - - "sce01130" - - "sce01200" - - "sce01230" - - "sce03018" - - kegg.reaction: "R01843" - - metanetx.reaction: "MNXR102510" - - sbo: "SBO:0000176" - - deltaG: -16.72 - - confidence_score: 2 - !!omap - id: "r_0888" - name: "phosphoglucomutase" @@ -52760,8 +51404,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR105C or YKL127W" - eccodes: "5.4.2.2" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "PGMT" - kegg.pathway: @@ -52794,8 +51437,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR256W or YHR183W" - eccodes: "1.1.1.44" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "GND" - kegg.pathway: @@ -52820,8 +51462,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL058W" - eccodes: "5.4.2.3" - - subsystem: - - "Amino sugar and nucleotide sugar metabolism" + - subsystem: "Amino sugar and nucleotide sugar metabolism" - annotation: !!omap - bigg.reaction: "PGAMT" - kegg.pathway: @@ -52848,8 +51489,7 @@ - eccodes: - "1.1.1.399" - "1.1.1.95" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "PGCD" - kegg.pathway: @@ -52875,8 +51515,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR012W" - eccodes: "2.7.2.3" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "PGK" - kegg.pathway: @@ -52901,8 +51540,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR283W or YKL152C" - eccodes: "5.4.2.11" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "PGM" - kegg.pathway: @@ -52928,8 +51566,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFL045C" - eccodes: "5.4.2.8" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - bigg.reaction: "PMANM" - kegg.pathway: @@ -52956,8 +51593,7 @@ - eccodes: - "2.7.1.49" - "2.7.4.7" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "PMPK" - kegg.pathway: "sce00730" @@ -52979,8 +51615,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR220W" - eccodes: "2.7.4.2" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "PMEVK" - kegg.pathway: @@ -53007,8 +51642,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL083C" - eccodes: "6.3.2.5" - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "PPNCL2" - kegg.pathway: "sce00770" @@ -53029,8 +51663,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL088W and YKR072C and YOR054C" - eccodes: "4.1.1.36" - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "PPCDC" - kegg.pathway: "sce00770" @@ -53051,8 +51684,7 @@ - eccodes: - "5.4.2.2" - "5.4.2.7" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "PPM" - kegg.pathway: @@ -53083,8 +51715,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAR015W" - eccodes: "6.3.2.6" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PRASCSi" - kegg.pathway: @@ -53111,8 +51742,7 @@ - "1.1.1.23" - "3.5.4.19" - "3.6.1.31" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - bigg.reaction: "PRAMPC" - kegg.pathway: @@ -53141,8 +51771,7 @@ - "1.1.1.23" - "3.5.4.19" - "3.6.1.31" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - bigg.reaction: "PRATPP" - kegg.pathway: @@ -53166,8 +51795,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR128C" - eccodes: "4.1.1.21" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - kegg.pathway: - "sce00230" @@ -53192,8 +51820,7 @@ - eccodes: - "2.1.2.3" - "3.5.4.10" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "AICART" - kegg.pathway: @@ -53216,8 +51843,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR007W" - eccodes: "5.3.1.24" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "PRAIi" - kegg.pathway: @@ -53248,8 +51874,7 @@ - eccodes: - "6.3.3.1" - "6.3.4.13" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PRAGSr" - kegg.pathway: @@ -53275,8 +51900,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR300C" - eccodes: "2.4.2.14" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "GLUPRT" - kegg.pathway: @@ -53302,8 +51926,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YKL181W and YER099C) or (YKL181W and YHL011C) or (YKL181W and YBL068W) or (YER099C and YOL061W) or (YBL068W and YOL061W)" - eccodes: "2.7.6.1" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "PRPPS" - kegg.pathway: @@ -53330,8 +51953,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR208W" - eccodes: "3.1.3.3" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "PSP_L" - kegg.pathway: @@ -53357,8 +51979,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR184W" - eccodes: "2.6.1.52" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "PSERT" - kegg.pathway: @@ -53385,8 +52006,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR183W" - eccodes: "3.5.1.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - metanetx.reaction: "MNXR126696" @@ -53409,8 +52029,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR402C" - eccodes: "1.14.14.-" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -53432,8 +52051,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR294C" - eccodes: "4.1.2.27" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - metanetx.reaction: "MNXR103262" @@ -53458,8 +52076,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR297W" - eccodes: "1.-.-.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - kegg.reaction: "R06525" @@ -53485,8 +52102,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR020W" - eccodes: "1.5.3.17" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "POLYAO" - kegg.pathway: @@ -53509,8 +52125,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL040C" - eccodes: "4.2.1.24" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "PPBNGS" - kegg.pathway: @@ -53535,8 +52150,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR020W" - eccodes: "1.5.3.17" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "POLYAO2" - kegg.pathway: @@ -53562,8 +52176,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR020W" - eccodes: "1.5.3.17" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "POLYAO3" - kegg.pathway: @@ -53588,8 +52201,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL316C" - eccodes: "4.2.1.51" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "PPNDH" - kegg.pathway: @@ -53610,15 +52222,14 @@ - metabolites: !!omap - s_0204: 1 - s_0456: 1 - - s_1207: -1 - - s_1212: 1 + - s_1198: -1 + - s_1203: 1 - s_1377: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR166C" - eccodes: "1.3.1.13" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "PPND2" - kegg.pathway: @@ -53643,8 +52254,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR142W" - eccodes: "1.5.5.2" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - kegg.pathway: - "sce00330" @@ -53669,8 +52279,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR020W" - eccodes: "6.1.1.15" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "PROTRS_1" - kegg.pathway: "sce00970" @@ -53692,8 +52301,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER014W" - eccodes: "1.3.3.4" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "PPPGOm" - kegg.pathway: @@ -53720,8 +52328,7 @@ - "2.4.2.1" - "2.4.2.28" - "3.2.2.3" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "PNP" - kegg.pathway: @@ -53748,8 +52355,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR209C" - eccodes: "2.4.2.1" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PUNP3" - kegg.pathway: @@ -53775,8 +52381,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR209C" - eccodes: "2.4.2.1" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PUNP3m" - kegg.pathway: @@ -53802,8 +52407,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR209C" - eccodes: "2.4.2.1" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "PUNP5" - kegg.pathway: @@ -53831,8 +52435,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR035C" - eccodes: "1.4.3.5" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "PYDXO" - kegg.pathway: "sce00750" @@ -53854,8 +52457,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR035C" - eccodes: "1.4.3.5" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "PYAM5PO" - kegg.pathway: "sce00750" @@ -53876,8 +52478,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR035C" - eccodes: "1.4.3.5" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "PDX5POi" - kegg.pathway: "sce00750" @@ -53899,8 +52500,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR035C" - eccodes: "1.4.3.5" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "PYDXNO" - kegg.pathway: "sce00750" @@ -53922,8 +52522,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER023W" - eccodes: "1.5.1.2" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "P5CR" - kegg.pathway: @@ -53951,8 +52550,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR218C or YGL062W" - eccodes: "6.4.1.1" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "PC" - kegg.pathway: @@ -53981,8 +52579,7 @@ - "4.1.1.1" - "4.1.1.43" - "4.1.1.74" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "PYRDC" - kegg.pathway: @@ -54011,8 +52608,7 @@ - "4.1.1.1" - "4.1.1.43" - "4.1.1.74" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "PYRDC2" - kegg.pathway: @@ -54041,8 +52637,7 @@ - "1.2.4.1" - "1.8.1.4" - "2.3.1.12" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "PDHm" - kegg.pathway: @@ -54075,8 +52670,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAL038W or YOR347C" - eccodes: "2.7.1.40" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "PYK" - kegg.pathway: @@ -54113,8 +52707,7 @@ - "2.1.1.201" - "2.1.1.64" - "2.7.-.-" - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00130" @@ -54136,8 +52729,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR135C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR100447" - pubmed: "9729482" @@ -54157,8 +52749,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR236C" - eccodes: "2.7.1.26" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "RBFK" - kegg.pathway: @@ -54182,8 +52773,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR236C" - eccodes: "2.7.1.26" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "RBFKm" - kegg.pathway: @@ -54208,8 +52798,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL143C" - eccodes: "2.5.1.78" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "RBFSa" - kegg.pathway: @@ -54233,8 +52822,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR256C" - eccodes: "2.5.1.9" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "RBFSb" - kegg.pathway: @@ -54259,8 +52847,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR036W" - eccodes: "2.7.1.15" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "RBK" - kegg.pathway: "sce00030" @@ -54284,8 +52871,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGR209C" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "RNTR1" - kegg.reaction: "R02014" @@ -54307,8 +52893,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGR209C" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "RNTR3" - kegg.reaction: "R02022" @@ -54330,8 +52915,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGR209C" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "RNTR2" - kegg.reaction: "R02020" @@ -54353,8 +52937,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGR209C" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "RNTR4" - kegg.reaction: "R02023" @@ -54377,8 +52960,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER070W or YGR180C or YIL066C or YJL026W" - eccodes: "1.17.4.1" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "RNDR1" - kegg.pathway: @@ -54405,8 +52987,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER070W or YGR180C or YIL066C or YJL026W" - eccodes: "1.17.4.1" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "RNDR1n" - kegg.pathway: @@ -54433,8 +53014,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER070W or YGR180C or YIL066C or YJL026W" - eccodes: "1.17.4.1" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "RNDR3" - kegg.pathway: @@ -54461,8 +53041,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER070W or YGR180C or YIL066C or YJL026W" - eccodes: "1.17.4.1" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "RNDR3n" - kegg.pathway: @@ -54489,8 +53068,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER070W or YGR180C or YIL066C or YJL026W" - eccodes: "1.17.4.1" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "RNDR2" - kegg.pathway: @@ -54517,8 +53095,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER070W or YGR180C or YIL066C or YJL026W" - eccodes: "1.17.4.1" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "RNDR2n" - kegg.pathway: @@ -54541,8 +53118,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR095C" - eccodes: "5.3.1.6" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "RPI" - kegg.pathway: @@ -54571,8 +53147,7 @@ - eccodes: - "2.7.1.173" - "2.7.1.22" - - subsystem: - - "Nicotinate and nicotinamide metabolism" + - subsystem: "Nicotinate and nicotinamide metabolism" - annotation: !!omap - bigg.reaction: "RNMK" - kegg.pathway: "sce00760" @@ -54592,8 +53167,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL121C" - eccodes: "5.1.3.1" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "RPE" - kegg.pathway: @@ -54627,8 +53201,7 @@ - "2.1.1.201" - "2.1.1.64" - "2.7.-.-" - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - bigg.reaction: "3DH5HPBMTm" - kegg.pathway: @@ -54653,8 +53226,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML008C" - eccodes: "2.1.1.41" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "SAM24MT" - kegg.pathway: @@ -54679,8 +53251,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL068C" - eccodes: "3.1.2.12" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - bigg.reaction: "SFGTHi" - kegg.pathway: "sce01200" @@ -54705,8 +53276,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIR034C" - eccodes: "1.5.1.7" - - subsystem: - - "Lysine metabolism" + - subsystem: "Lysine metabolism" - annotation: !!omap - bigg.reaction: "SACCD2" - kegg.pathway: @@ -54736,8 +53306,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR050C" - eccodes: "1.5.1.10" - - subsystem: - - "Lysine metabolism" + - subsystem: "Lysine metabolism" - annotation: !!omap - bigg.reaction: "SACCD1" - kegg.pathway: @@ -54763,8 +53332,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL060C" - eccodes: "4.1.2.13" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "FBA3" - kegg.pathway: @@ -54791,8 +53359,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YHR013C and YDL040C and YOR253W" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "SERAT" - kegg.reaction: "R00586" @@ -54815,8 +53382,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR296C and YKL212W and YDR062W and YGR038W and YLR350W and YBR058C-A" - eccodes: "2.3.1.50" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00600" @@ -54846,8 +53412,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR023W or YHR011W" - eccodes: "6.1.1.11" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "SERTRS" - kegg.pathway: "sce00970" @@ -54875,8 +53440,7 @@ - "2.7.1.71" - "4.2.1.10" - "4.2.3.4" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "SHK3Dr" - kegg.pathway: @@ -54908,8 +53472,7 @@ - "2.7.1.71" - "4.2.1.10" - "4.2.3.4" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "SHKK" - kegg.pathway: @@ -54938,8 +53501,7 @@ - eccodes: - "1.3.1.76" - "4.99.1.4" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "SHCHD2" - kegg.pathway: @@ -54966,8 +53528,7 @@ - eccodes: - "1.3.1.76" - "4.99.1.4" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "SHCHF" - kegg.pathway: @@ -54993,8 +53554,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL047C" - eccodes: "1.3.1.6" - - subsystem: - - "Cellular response to anaerobic conditions" + - subsystem: "Cellular response to anaerobic conditions" - annotation: !!omap - kegg.reaction: "R00408" - metanetx.reaction: "MNXR129857" @@ -55018,8 +53578,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR069C" - eccodes: "2.5.1.16" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "SPMS" - kegg.pathway: @@ -55045,8 +53604,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR146C" - eccodes: "2.5.1.22" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "SPRMS" - kegg.pathway: @@ -55070,8 +53628,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR294C" - eccodes: "4.1.2.27" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - bigg.reaction: "SGPL11r" - kegg.pathway: "sce00600" @@ -55095,8 +53652,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL134W or YKR053C" - eccodes: "3.1.3.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - bigg.reaction: "SBPP2er" - kegg.pathway: "sce00600" @@ -55120,8 +53676,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL134W or YKR053C" - eccodes: "3.1.3.-" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - bigg.reaction: "SBPP1er" - kegg.pathway: "sce00600" @@ -55147,8 +53702,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR260W or YOR171C" - eccodes: "2.7.1.91" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - metanetx.reaction: "MNXR104440" @@ -55171,8 +53725,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR260W or YOR171C" - eccodes: "2.7.1.91" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00600" - kegg.reaction: "R02976" @@ -55191,8 +53744,7 @@ - s_1504: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "C5-branched dibasic acid metabolism" + - subsystem: "C5-branched dibasic acid metabolism" - annotation: !!omap - kegg.reaction: "R02244" - metanetx.reaction: "MNXR95382" @@ -55208,8 +53760,7 @@ - s_1503: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "C5-branched dibasic acid metabolism" + - subsystem: "C5-branched dibasic acid metabolism" - annotation: !!omap - bigg.reaction: "ACONIs" - kegg.reaction: "R02244" @@ -55233,8 +53784,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR175C" - eccodes: "1.14.14.17" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "SQLErx" - kegg.pathway: @@ -55262,8 +53812,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR175C" - eccodes: "1.14.14.17" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "SQLEr" - kegg.pathway: @@ -55291,8 +53840,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR190W" - eccodes: "2.5.1.21" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "SQLS" - kegg.pathway: @@ -55317,8 +53865,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YDR178W and YJL045W and YKL141W and YLL041C) or (YDR178W and YKL141W and YKL148C and YLL041C) or (YLR164W and YJL045W and YKL141W and YLL041C)" - eccodes: "1.3.5.1" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "SUCD2_u6m" - kegg.pathway: @@ -55346,8 +53893,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR244C and YOR142W" - eccodes: "6.2.1.5" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "SUCOASm" - kegg.pathway: @@ -55376,8 +53922,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR006W" - eccodes: "1.2.1.16" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "SSALy" - kegg.pathway: @@ -55404,8 +53949,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL162W" - eccodes: "3.2.1.26" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "SUCRe" - kegg.pathway: @@ -55429,8 +53973,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR010W" - eccodes: "2.7.7.4" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - bigg.reaction: "SADT" - kegg.pathway: @@ -55458,8 +54001,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL050C" - eccodes: "2.7.7.5" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - bigg.reaction: "SLFAT" - kegg.pathway: @@ -55485,8 +54027,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR030W and YJR137C" - eccodes: "1.8.1.2" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - bigg.reaction: "SULR" - kegg.pathway: "sce00920" @@ -55510,8 +54051,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YLL048C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR104744" - pubmed: "9182565" @@ -55534,8 +54074,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL057C" - eccodes: "1.14.11.-" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - bigg.reaction: "TAUDO" - kegg.reaction: "R05320" @@ -55559,8 +54098,7 @@ - "1.4.4.2" - "1.8.1.4" - "2.1.2.10" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "THFATm" - kegg.pathway: @@ -55595,8 +54133,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL132C or YOR241W" - eccodes: "6.3.2.17" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "THFGLUS" - kegg.pathway: "sce00790" @@ -55622,8 +54159,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR092C" - eccodes: "3.1.3.2" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "THMDPe" - kegg.pathway: @@ -55646,8 +54182,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR092C" - eccodes: "3.1.3.2" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "THMPe" - kegg.pathway: @@ -55671,8 +54206,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR143C" - eccodes: "2.7.6.2" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "TMDPK" - kegg.pathway: "sce00730" @@ -55693,8 +54227,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR143C" - eccodes: "2.7.6.2" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "TMDPPK" - kegg.pathway: "sce00730" @@ -55718,8 +54251,7 @@ - eccodes: - "2.5.1.3" - "2.7.1.50" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "TMPPP" - kegg.pathway: "sce00730" @@ -55741,8 +54273,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YGR209C and YIL010W) or (YIL010W and YLR043C)" - eccodes: "1.11.1.15" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "THIORDXni" - metanetx.reaction: "MNXR104815" @@ -55763,8 +54294,7 @@ - upper_bound: 1000 - gene_reaction_rule: "(YDR353W and YGR209C) or (YDR353W and YLR043C) or YDR353W" - eccodes: "1.8.1.9" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "TRDR" - kegg.pathway: "sce00450" @@ -55788,8 +54318,7 @@ - eccodes: - "1.8.1.7" - "1.8.1.9" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "TRDRm" - kegg.pathway: @@ -55813,8 +54342,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL046C" - eccodes: "4.1.2.48" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "THRA" - kegg.pathway: @@ -55840,8 +54368,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR053W" - eccodes: "4.2.3.1" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "THRS" - kegg.pathway: @@ -55869,8 +54396,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL078W" - eccodes: "6.1.1.3" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "THRTRS" - kegg.pathway: "sce00970" @@ -55894,8 +54420,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL194C" - eccodes: "6.1.1.3" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "THRTRSm" - kegg.pathway: "sce00970" @@ -55917,8 +54442,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR074C" - eccodes: "2.1.1.45" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "TMDS" - kegg.pathway: @@ -55941,8 +54465,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER175C" - eccodes: "2.1.1.145" - - subsystem: - - "C5-branched dibasic acid metabolism" + - subsystem: "C5-branched dibasic acid metabolism" - annotation: !!omap - bigg.reaction: "ACONMT" - kegg.reaction: "R05763" @@ -55963,8 +54486,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR003W" - eccodes: "2.5.1.-" - - subsystem: - - "Terpenoid backbone biosynthesis" + - subsystem: "Terpenoid backbone biosynthesis" - annotation: !!omap - bigg.reaction: "PPTTm" - kegg.pathway: @@ -55988,8 +54510,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR043C or YLR354C" - eccodes: "2.2.1.2" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "TALA" - kegg.pathway: @@ -56015,8 +54536,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR117C or YPR074C" - eccodes: "2.2.1.1" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "TKT1" - kegg.pathway: @@ -56042,8 +54562,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR117C or YPR074C" - eccodes: "2.2.1.1" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "TKT2" - kegg.pathway: @@ -56070,8 +54589,7 @@ - eccodes: - "2.4.1.15" - "3.1.3.12" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "TRE6PP" - kegg.pathway: "sce00500" @@ -56091,8 +54609,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR050C" - eccodes: "5.3.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "TPI" - kegg.pathway: @@ -56122,8 +54639,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL026C" - eccodes: "4.2.1.20" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "TRPS1" - kegg.pathway: @@ -56151,8 +54667,7 @@ - eccodes: - "2.6.1.39" - "2.6.1.57" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "TRPTA" - kegg.pathway: @@ -56189,8 +54704,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL097C" - eccodes: "6.1.1.2" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "TRPTRS" - kegg.pathway: "sce00970" @@ -56214,8 +54728,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR268W" - eccodes: "6.1.1.2" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "TRPTRSm" - kegg.pathway: "sce00970" @@ -56239,8 +54752,7 @@ - eccodes: - "2.6.1.39" - "2.6.1.57" - - subsystem: - - "Tyrosine metabolism" + - subsystem: "Tyrosine metabolism" - annotation: !!omap - bigg.reaction: "TYRTA" - kegg.pathway: @@ -56275,8 +54787,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR027C" - eccodes: "2.6.1.1" - - subsystem: - - "Tyrosine metabolism" + - subsystem: "Tyrosine metabolism" - annotation: !!omap - bigg.reaction: "TYRTAip" - kegg.pathway: @@ -56311,8 +54822,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR185C" - eccodes: "6.1.1.1" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "TYRTRS" - kegg.pathway: "sce00970" @@ -56336,8 +54846,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL097W" - eccodes: "6.1.1.1" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "TYRTRSm" - kegg.pathway: "sce00970" @@ -56360,8 +54869,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR189C" - eccodes: "2.4.1.173" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "ERGSTGLCT" - pubmed: "10224056" @@ -56381,8 +54889,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL103C" - eccodes: "2.7.7.23" - - subsystem: - - "Amino sugar and nucleotide sugar metabolism" + - subsystem: "Amino sugar and nucleotide sugar metabolism" - annotation: !!omap - kegg.pathway: - "sce00520" @@ -56405,8 +54912,7 @@ - eccodes: - "5.1.3.2" - "5.1.3.3" - - subsystem: - - "Galactose metabolism" + - subsystem: "Galactose metabolism" - annotation: !!omap - bigg.reaction: "UDPG4E" - kegg.pathway: @@ -56433,8 +54939,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR018C" - eccodes: "2.7.7.12" - - subsystem: - - "Galactose metabolism" + - subsystem: "Galactose metabolism" - annotation: !!omap - bigg.reaction: "UGLT" - kegg.pathway: @@ -56458,8 +54963,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL024C" - eccodes: "2.7.4.14" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "UMPK" - kegg.pathway: "sce00240" @@ -56480,8 +54984,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL024C" - eccodes: "2.7.4.14" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "UMPKn" - kegg.pathway: "sce00240" @@ -56502,8 +55005,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR128W" - eccodes: "2.4.2.9" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "UPPRT" - kegg.pathway: "sce00240" @@ -56529,8 +55031,7 @@ - eccodes: - "3.5.1.54" - "6.3.4.6" - - subsystem: - - "Arginine biosynthesis" + - subsystem: "Arginine biosynthesis" - annotation: !!omap - bigg.reaction: "UREASE" - kegg.pathway: @@ -56555,8 +55056,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIR032C" - eccodes: "4.3.2.3" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "UGLYCH" - kegg.pathway: "sce00230" @@ -56579,8 +55079,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR020C or YNR012W" - eccodes: "2.7.1.48" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "URIK1" - kegg.pathway: "sce00240" @@ -56602,8 +55101,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR020C or YNR012W" - eccodes: "2.7.1.48" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "URIK2" - kegg.pathway: "sce00240" @@ -56624,8 +55122,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL024C" - eccodes: "2.7.4.14" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "URIDK2r" - kegg.pathway: "sce00240" @@ -56646,8 +55143,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL024C" - eccodes: "2.7.4.14" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "URIDK2rn" - kegg.pathway: "sce00240" @@ -56668,8 +55164,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR047W" - eccodes: "4.1.1.37" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "UPPDC1" - kegg.pathway: @@ -56693,8 +55188,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR069W" - eccodes: "2.1.1.107" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "UPP3MT" - kegg.pathway: @@ -56716,8 +55210,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR278W" - eccodes: "4.2.1.75" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "UPP3S" - kegg.pathway: @@ -56741,8 +55234,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHL012W or YKL035W" - eccodes: "2.7.7.9" - - subsystem: - - "Galactose metabolism" + - subsystem: "Galactose metabolism" - annotation: !!omap - bigg.reaction: "GALUi" - kegg.pathway: @@ -56774,8 +55266,7 @@ - eccodes: - "3.1.-.-" - "3.6.3.14" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - kegg.pathway: - "sce00190" @@ -56803,8 +55294,7 @@ - eccodes: - "3.1.-.-" - "3.6.3.14" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - kegg.pathway: - "sce00190" @@ -56828,8 +55318,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR148W" - eccodes: "2.6.1.42" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "VALTA" - kegg.pathway: @@ -56859,8 +55348,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR208W" - eccodes: "2.6.1.42" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "VALTAim" - kegg.pathway: @@ -56892,8 +55380,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR094W" - eccodes: "6.1.1.9" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "VALTRS" - kegg.pathway: "sce00970" @@ -56917,8 +55404,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR094W" - eccodes: "6.1.1.9" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - bigg.reaction: "VALTRSm" - kegg.pathway: "sce00970" @@ -56940,8 +55426,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR133W" - eccodes: "2.4.2.-" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "XPPT" - kegg.reaction: "R02142" @@ -56962,8 +55447,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR070C" - eccodes: "1.1.1.9" - - subsystem: - - "Pentose and glucuronate interconversions" + - subsystem: "Pentose and glucuronate interconversions" - annotation: !!omap - bigg.reaction: "XYLTD_D" - kegg.pathway: "sce00040" @@ -56987,8 +55471,7 @@ - eccodes: - "1.1.1.-" - "1.1.1.21" - - subsystem: - - "Pentose and glucuronate interconversions" + - subsystem: "Pentose and glucuronate interconversions" - annotation: !!omap - bigg.reaction: "XYLR" - kegg.pathway: "sce00040" @@ -57010,8 +55493,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR194C" - eccodes: "2.7.1.17" - - subsystem: - - "Pentose and glucuronate interconversions" + - subsystem: "Pentose and glucuronate interconversions" - annotation: !!omap - bigg.reaction: "XYLK" - kegg.pathway: "sce00040" @@ -57036,8 +55518,7 @@ - "5.4.99.25" - "5.4.99.44" - "5.4.99.45" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -11.95 @@ -57051,8 +55532,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNL065W or YKL217W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "MEV_Rt" - metanetx.reaction: "MNXR105406" @@ -57068,8 +55548,7 @@ - s_0036: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "BTDt_RR" - metanetx.reaction: "MNXR136615" @@ -57085,8 +55564,7 @@ - s_0173: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "2MBACt" - metanetx.reaction: "MNXR94808" @@ -57105,8 +55583,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YOR222W or YPL134C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "2OXOADPTm" - metanetx.reaction: "MNXR94819" @@ -57124,8 +55601,7 @@ - s_0213: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "3DH5HPBtm" - metanetx.reaction: "MNXR94863" @@ -57144,8 +55620,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDL210W or YOR348C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ABUTt2r" - metanetx.reaction: "MNXR94994" @@ -57163,8 +55638,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDL210W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "5AOPt2" - metanetx.reaction: "MNXR95061" @@ -57179,8 +55653,7 @@ - s_0320: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR95074" - pubmed: "8573145" @@ -57195,11 +55668,10 @@ - s_0354: -1 - s_0794: 1 - s_0796: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YNR056C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "8AONNt2" - metanetx.reaction: "MNXR95113" @@ -57216,8 +55688,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCR010C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ACtr" - metanetx.reaction: "MNXR95431" @@ -57233,8 +55704,7 @@ - s_0686: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - pubmed: "10653746" - sbo: "SBO:0000655" @@ -57251,8 +55721,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER056C or YER060W or YER060W-A" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ADEt2" - metanetx.reaction: "MNXR95446" @@ -57270,8 +55739,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YAL022C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ADNt2" - metanetx.reaction: "MNXR95461" @@ -57290,8 +55758,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBL030C or YBR085W or YMR056C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ATPtm" - kegg.reaction: "R00124" @@ -57316,8 +55783,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YPR128C" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "ATPtp_H" - metanetx.reaction: "MNXR96139" @@ -57335,8 +55801,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YMR241W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "AKGCITtm" - metanetx.reaction: "MNXR95654" @@ -57353,8 +55818,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ALLTTti" - metanetx.reaction: "MNXR95773" @@ -57370,8 +55834,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YIR028W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ALLTNti" - metanetx.reaction: "MNXR95771" @@ -57387,8 +55850,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDR384C or YGR121C or YNL142W or YPR138C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "NH4t" - metanetx.reaction: "MNXR101950" @@ -57409,8 +55871,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YPR128C" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "ATP2tp_H" - metanetx.reaction: "MNXR96125" @@ -57428,8 +55889,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YPR021C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ASPGLU2m" - metanetx.reaction: "MNXR96083" @@ -57448,8 +55908,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGR065C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "BTNt2i" - metanetx.reaction: "MNXR96334" @@ -57467,8 +55926,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOR100C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "CRNCARtm" - metanetx.reaction: "MNXR96898" @@ -57483,8 +55941,7 @@ - s_0488: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - pubmed: "12484746" - sbo: "SBO:0000655" @@ -57498,8 +55955,7 @@ - s_0491: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - pubmed: "12484746" - sbo: "SBO:0000655" @@ -57513,8 +55969,7 @@ - s_0494: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - pubmed: "12484746" - sbo: "SBO:0000655" @@ -57528,8 +55983,7 @@ - s_0497: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - pubmed: "12484746" - sbo: "SBO:0000655" @@ -57546,8 +56000,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGL077C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CHLt2" - metanetx.reaction: "MNXR96692" @@ -57565,8 +56018,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR291C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "CITtam" - metanetx.reaction: "MNXR96753" @@ -57584,8 +56036,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR291C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "CITtbm" - metanetx.reaction: "MNXR96754" @@ -57603,8 +56054,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR291C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "CITtcm" - metanetx.reaction: "MNXR96755" @@ -57620,8 +56070,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YHR002W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "COAtim" - metanetx.reaction: "MNXR96815" @@ -57642,8 +56091,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR192W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - pubmed: "16844075" - sbo: "SBO:0000655" @@ -57662,8 +56110,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR192W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "CTPtm" - metanetx.reaction: "MNXR96947" @@ -57682,8 +56129,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YAL022C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CYTDt2" - metanetx.reaction: "MNXR97044" @@ -57702,8 +56148,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER056C or YER060W or YER060W-A or YGL186C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CSNt2" - metanetx.reaction: "MNXR96929" @@ -57719,8 +56164,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDL245C or YDR342C or YDR343C or YDR345C or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YMR011W or YNR072W or YOL156W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "FRUt2" - kegg.pathway: "sce04113" @@ -57740,8 +56184,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YFL011W or YJL219W or YLR081W or YNL318C or YOL156W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GALt2" - kegg.pathway: "sce04113" @@ -57757,11 +56200,10 @@ - s_0026: -1 - s_0794: 1 - s_0796: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL217W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "D_LACt2" - metanetx.reaction: "MNXR97838" @@ -57778,8 +56220,7 @@ - s_0799: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "D_LACtm" - metanetx.reaction: "MNXR97838" @@ -57797,8 +56238,7 @@ - s_1401: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "D_LACt2m" - metanetx.reaction: "MNXR97839" @@ -57817,8 +56257,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDL245C or YDR342C or YHR094C or YDR343C or YDR345C or YEL069C or YFL011W or YHR096C or YJL214W or YJL219W or YJR158W or YNR072W or YOL156W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "MANt2" - kegg.pathway: "sce04113" @@ -57835,8 +56274,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL013C or YOR011W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "EPISTt" - metanetx.reaction: "MNXR97944" @@ -57853,8 +56291,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL013C or YOR011W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ERGSTt" - metanetx.reaction: "MNXR97950" @@ -57871,8 +56308,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL013C or YOR011W" - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR97950" - pubmed: "17434796" @@ -57888,8 +56324,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YGL077C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ETHAt" - metanetx.reaction: "MNXR97974" @@ -57906,8 +56341,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YIL134W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "FADH2tm" - metanetx.reaction: "MNXR99212" @@ -57924,8 +56358,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL013C or YOR011W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "FECOSTt" - metanetx.reaction: "MNXR99529" @@ -57942,8 +56375,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL013C or YOR011W" - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR99529" - pubmed: "17434796" @@ -57958,8 +56390,7 @@ - s_0720: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "r0963" - metanetx.reaction: "MNXR105408" @@ -57978,8 +56409,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGL225W" - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - bigg.reaction: "GDPMANNtg" - metanetx.reaction: "MNXR100090" @@ -57996,8 +56426,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDL245C or YDL247W or YDR342C or YDR343C or YDR345C or YDR536W or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YJR160C or YLR081W or YMR011W or YNR072W or YOL156W or YDR387C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GLCt1" - kegg.pathway: "sce04113" @@ -58015,8 +56444,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJL212C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GTHRDt2" - metanetx.reaction: "MNXR100449" @@ -58033,8 +56461,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDR135C or YLL015W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR100449" - pubmed: "10790694" @@ -58050,8 +56477,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCR098C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "G3PIt" - metanetx.reaction: "MNXR99888" @@ -58068,8 +56494,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCR098C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "G3PCt" - metanetx.reaction: "MNXR99874" @@ -58088,8 +56513,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR536W or YGL084C or YPL189W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GLYCt2" - metanetx.reaction: "MNXR100344" @@ -58108,8 +56532,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YFL054C or YLL043W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GLYCt" - metanetx.reaction: "MNXR100343" @@ -58127,8 +56550,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCL025C or YKR039W or YOL020W or YOR348C or YPL265W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GLYt2r" - metanetx.reaction: "MNXR100368" @@ -58144,8 +56566,7 @@ - s_0774: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "GLCNtv" - metanetx.reaction: "MNXR100211" @@ -58166,8 +56587,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDL198C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "GTPt2m" - metanetx.reaction: "MNXR100461" @@ -58183,11 +56603,10 @@ - s_0788: -1 - s_0794: 1 - s_0796: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER056C or YER060W or YER060W-A" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GUAt2r" - metanetx.reaction: "MNXR100466" @@ -58205,8 +56624,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR497C or YOL103W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "INSTt2" - metanetx.reaction: "MNXR100841" @@ -58222,8 +56640,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YMR319C or YMR058W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "FE2t" - metanetx.reaction: "MNXR99505" @@ -58240,8 +56657,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJL133W or YKR052C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "FE2utm" - metanetx.reaction: "MNXR99505" @@ -58257,8 +56673,7 @@ - s_0928: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "IAMACt" - metanetx.reaction: "MNXR100774" @@ -58274,8 +56689,7 @@ - s_0936: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "IBUTACt" - metanetx.reaction: "MNXR100779" @@ -58291,8 +56705,7 @@ - s_0945: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "IPDPtm" - metanetx.reaction: "MNXR100876" @@ -58308,11 +56721,10 @@ - s_0796: -1 - s_0955: 1 - s_0956: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YCL025C or YKR039W or YOR348C or YPL265W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ALAt2r" - metanetx.reaction: "MNXR95704" @@ -58330,11 +56742,10 @@ - s_0796: -1 - s_0965: 1 - s_0966: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YEL063C or YKR039W or YNL270C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ARGt2r" - metanetx.reaction: "MNXR95953" @@ -58352,8 +56763,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOL092W or YBR293W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "ARGt6" - metanetx.reaction: "MNXR95954" @@ -58369,11 +56779,10 @@ - s_0796: -1 - s_0969: 1 - s_0970: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YCL025C or YDR508C or YKR039W or YPL265W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ASNt2r" - metanetx.reaction: "MNXR96066" @@ -58392,8 +56801,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR001W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "ASNt6" - metanetx.reaction: "MNXR96067" @@ -58412,8 +56820,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL146W or YNL101W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "ASNt7" - kegg.pathway: "sce04138" @@ -58433,8 +56840,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER119C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "ASPt7" - metanetx.reaction: "MNXR96106" @@ -58450,11 +56856,10 @@ - s_0796: -1 - s_0973: 1 - s_0974: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YFL055W or YKR039W or YPL265W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ASPt2r" - metanetx.reaction: "MNXR96106" @@ -58470,8 +56875,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR132C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CRNt" - metanetx.reaction: "MNXR96906" @@ -58486,11 +56890,10 @@ - s_0796: -1 - s_0981: 1 - s_0982: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W or YOL020W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CYSt2r" - metanetx.reaction: "MNXR97027" @@ -58509,8 +56912,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YCR075C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "LCYSTintv" - metanetx.reaction: "MNXR101034" @@ -58527,8 +56929,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YPR021C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "GLUt7m" - metanetx.reaction: "MNXR100301" @@ -58547,8 +56948,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER119C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "GLUt7" - metanetx.reaction: "MNXR100300" @@ -58564,11 +56964,10 @@ - s_0796: -1 - s_0991: 1 - s_0992: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YCL025C or YFL055W or YKR039W or YPL265W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GLUt2r" - metanetx.reaction: "MNXR100300" @@ -58586,8 +56985,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR001W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "GLNt6" - metanetx.reaction: "MNXR100262" @@ -58606,8 +57004,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL146W or YNL101W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "GLNt7" - kegg.pathway: "sce04138" @@ -58624,11 +57021,10 @@ - s_0796: -1 - s_0999: 1 - s_1000: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YCL025C or YDR508C or YKR039W or YPL265W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GLNt2r" - metanetx.reaction: "MNXR100260" @@ -58646,8 +57042,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOL092W or YBR293W or YCL069W or YMR088C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "HISt6" - metanetx.reaction: "MNXR100647" @@ -58663,11 +57058,10 @@ - s_0796: -1 - s_1006: 1 - s_1007: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR069C or YGR191W or YKR039W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "HISt2r" - metanetx.reaction: "MNXR100645" @@ -58683,8 +57077,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCL038C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - kegg.pathway: "sce04138" - metanetx.reaction: "MNXR100824" @@ -58703,8 +57096,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR001W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "ILEt6" - metanetx.reaction: "MNXR100825" @@ -58723,8 +57115,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL146W or YNL101W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "ILEt7" - kegg.pathway: "sce04138" @@ -58741,11 +57132,10 @@ - s_0796: -1 - s_1016: 1 - s_1017: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR068C or YBR069C or YCL025C or YDR046C or YKR039W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ILEt2r" - metanetx.reaction: "MNXR100822" @@ -58761,8 +57151,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKL217W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "L_LACtcm" - metanetx.reaction: "MNXR100999" @@ -58781,8 +57170,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL217W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "L_LACt2r" - metanetx.reaction: "MNXR101277" @@ -58799,8 +57187,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCL038C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - kegg.pathway: "sce04138" - metanetx.reaction: "MNXR101057" @@ -58819,8 +57206,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR001W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "LEUt6" - metanetx.reaction: "MNXR101058" @@ -58839,8 +57225,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL146W or YNL101W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "LEUt7" - kegg.pathway: "sce04138" @@ -58857,11 +57242,10 @@ - s_0796: -1 - s_1021: 1 - s_1022: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "LEUt2r" - metanetx.reaction: "MNXR101055" @@ -58879,8 +57263,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOL092W or YBR293W or YCL069W or YMR088C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "LYSt6" - metanetx.reaction: "MNXR101267" @@ -58896,11 +57279,10 @@ - s_0796: -1 - s_1025: 1 - s_1026: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKR039W or YNL268W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "LYSt2r" - metanetx.reaction: "MNXR101266" @@ -58915,11 +57297,10 @@ - s_0796: -1 - s_1029: 1 - s_1030: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR068C or YCL025C or YDR046C or YDR508C or YGR055W or YHL036W or YKR039W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "METt2r" - metanetx.reaction: "MNXR101490" @@ -58934,11 +57315,10 @@ - s_0796: -1 - s_1032: 1 - s_1033: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR068C or YCL025C or YDR046C or YKR039W or YOL020W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PHEt2r" - metanetx.reaction: "MNXR102635" @@ -58953,11 +57333,10 @@ - s_0796: -1 - s_1035: 1 - s_1036: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKR039W or YOR348C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PROt2r" - metanetx.reaction: "MNXR103211" @@ -58972,11 +57351,10 @@ - s_0796: -1 - s_1039: 1 - s_1041: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YCL025C or YDR508C or YFL055W or YKR039W or YPL265W or YDR105C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "SERt2r" - metanetx.reaction: "MNXR104352" @@ -58991,11 +57369,10 @@ - s_0796: -1 - s_1045: 1 - s_1046: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YCL025C or YDR508C or YKR039W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "THRt2r" - metanetx.reaction: "MNXR104850" @@ -59011,11 +57388,10 @@ - s_0796: -1 - s_1048: 1 - s_1049: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR068C or YBR069C or YDR046C or YKR039W or YOL020W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "TRPt2r" - metanetx.reaction: "MNXR104950" @@ -59032,8 +57408,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCL038C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - kegg.pathway: "sce04138" - metanetx.reaction: "MNXR105002" @@ -59052,8 +57427,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR293W or YJR001W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "TYRt6" - metanetx.reaction: "MNXR105005" @@ -59072,8 +57446,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL146W or YNL101W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "TYRt7" - kegg.pathway: "sce04138" @@ -59090,11 +57463,10 @@ - s_0796: -1 - s_1051: 1 - s_1052: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR068C or YBR069C or YCL025C or YDR046C or YKR039W or YOL020W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "TYRt2r" - metanetx.reaction: "MNXR105003" @@ -59109,11 +57481,10 @@ - s_0796: -1 - s_1056: 1 - s_1057: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR068C or YBR069C or YCL025C or YDR046C or YKR039W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "VALt2r" - metanetx.reaction: "MNXR105188" @@ -59129,8 +57500,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL013C or YOR011W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "LANOSTt" - metanetx.reaction: "MNXR101014" @@ -59149,8 +57519,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YLR348C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "MALtm" - metanetx.reaction: "MNXR101374" @@ -59168,8 +57537,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR298C or YDL247W or YGR289C or YJR160C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "MALTt2" - metanetx.reaction: "MNXR101365" @@ -59186,8 +57554,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR180W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - pubmed: "12455697" - sbo: "SBO:0000655" @@ -59202,8 +57569,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YEL006W or YIL006W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "NADtm" - metanetx.reaction: "MNXR101900" @@ -59224,8 +57590,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YIL006W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - pubmed: "16291748" - sbo: "SBO:0000655" @@ -59242,8 +57607,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YIL006W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - pubmed: "16291748" - sbo: "SBO:0000655" @@ -59260,8 +57624,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YIL006W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - pubmed: "16291748" - sbo: "SBO:0000655" @@ -59276,8 +57639,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YGR260W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "NACt" - metanetx.reaction: "MNXR101808" @@ -59294,8 +57656,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - metanetx.reaction: "MNXR99109" - pubmed: "8993619" @@ -59313,8 +57674,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOR130C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ORNt3m" - metanetx.reaction: "MNXR102225" @@ -59330,11 +57690,10 @@ - s_0796: -1 - s_1266: 1 - s_1267: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKR039W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ORNt2r" - metanetx.reaction: "MNXR102224" @@ -59352,8 +57711,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL120W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "OAAt2m" - metanetx.reaction: "MNXR102102" @@ -59368,11 +57726,10 @@ - s_0032: -1 - s_0794: 1 - s_0796: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YCR028C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PNTOt2" - metanetx.reaction: "MNXR103053" @@ -59387,8 +57744,7 @@ - s_1313: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "PENDPtm" - metanetx.reaction: "MNXR102483" @@ -59404,8 +57760,7 @@ - s_1317: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PHEACt" - metanetx.reaction: "MNXR102622" @@ -59421,11 +57776,10 @@ - s_0796: -1 - s_1322: 1 - s_1324: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR296C or YCR037C or YJL198W or YML123C or YNR013C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PIt2r" - metanetx.reaction: "MNXR102872" @@ -59443,8 +57797,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER053C or YJR077C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "PIt2m" - metanetx.reaction: "MNXR102872" @@ -59459,11 +57812,10 @@ - s_0796: -1 - s_1373: 1 - s_1374: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR456W or YJL129C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "Kt2r" - pubmed: "3043197" @@ -59479,8 +57831,7 @@ - lower_bound: 0 - upper_bound: 0 - gene_reaction_rule: "YKL174C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PTRCtex2" - metanetx.reaction: "MNXR103339" @@ -59497,10 +57848,9 @@ - s_1389: 1 - s_1390: -1 - lower_bound: -1000 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YLL028W or YOR273C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PTRCt3i" - metanetx.reaction: "MNXR103341" @@ -59519,8 +57869,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YLL028W or YOR273C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR103341" - pubmed: "11171066" @@ -59535,11 +57884,10 @@ - s_0796: -1 - s_1396: 1 - s_1397: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGL186C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - pubmed: "12649274" - sbo: "SBO:0000655" @@ -59553,11 +57901,10 @@ - s_0796: -1 - s_1399: 1 - s_1400: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL217W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PYRt2" - metanetx.reaction: "MNXR103385" @@ -59575,8 +57922,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YPL274W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "AMETt2" - metanetx.reaction: "MNXR95810" @@ -59592,8 +57938,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNL003C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "AMETtm" - metanetx.reaction: "MNXR95809" @@ -59612,8 +57957,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YLL061W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "MMETt2" - metanetx.reaction: "MNXR101658" @@ -59631,8 +57975,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDR456W or YLR138W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "NAt3_1" - sbo: "SBO:0000655" @@ -59647,8 +57990,7 @@ - lower_bound: 0 - upper_bound: 0 - gene_reaction_rule: "YKL174C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "SPMDtex2" - metanetx.reaction: "MNXR104495" @@ -59665,10 +58007,9 @@ - s_1439: 1 - s_1440: -1 - lower_bound: -1000 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YBR132C or YHL016C or YKR039W or YLL028W or YOR273C or YPL274W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "SPMDt3i" - metanetx.reaction: "MNXR104497" @@ -59689,8 +58030,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YLL028W or YOR273C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR104497" - pubmed: "11171066" @@ -59706,10 +58046,9 @@ - s_1442: 1 - s_1443: -1 - lower_bound: -1000 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YGR138C or YLL028W or YOR273C or YPR156C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "SPRMt2i" - metanetx.reaction: "MNXR104501" @@ -59728,8 +58067,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YGR138C or YLL028W or YOR273C or YPR156C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR104501" - pubmed: "11171066" @@ -59747,8 +58085,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YLR348C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "SUCCtm" - metanetx.reaction: "MNXR104626" @@ -59766,8 +58103,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR095W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "SUCFUMtm" - metanetx.reaction: "MNXR104633" @@ -59784,8 +58120,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR294W or YLR092W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "SO4ti" - metanetx.reaction: "MNXR104469" @@ -59801,8 +58136,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YPL092W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "SO3ti" - metanetx.reaction: "MNXR104460" @@ -59818,8 +58152,7 @@ - s_1472: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "TAURt" - metanetx.reaction: "MNXR104733" @@ -59836,8 +58169,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGR096W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "THMPPt2m" - metanetx.reaction: "MNXR104824" @@ -59856,8 +58188,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YLR237W or YOR071C or YOR192C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "THMt2" - metanetx.reaction: "MNXR138863" @@ -59874,8 +58205,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YPL244C" - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - bigg.reaction: "UDPGALt2g" - metanetx.reaction: "MNXR105061" @@ -59894,8 +58224,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR021W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "URAt2" - metanetx.reaction: "MNXR105148" @@ -59910,11 +58239,10 @@ - s_0796: -2 - s_1552: 1 - s_1553: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YHL016C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "UREA2t2" - metanetx.reaction: "MNXR105154" @@ -59932,8 +58260,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBL042C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "URIt2" - metanetx.reaction: "MNXR105166" @@ -59956,8 +58283,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR192W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - pubmed: "16844075" - sbo: "SBO:0000655" @@ -59976,8 +58302,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR192W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "UTPtm" - metanetx.reaction: "MNXR105175" @@ -59994,8 +58319,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YLL052C or YPR192W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "H2Ot" - metanetx.reaction: "MNXR98641" @@ -60012,8 +58336,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL013C or YOR011W" - - subsystem: - - "Transport [e, ce]" + - subsystem: "Transport [e, ce]" - annotation: !!omap - metanetx.reaction: "MNXR105285" - pubmed: "12077145" @@ -60030,8 +58353,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60047,8 +58369,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60064,8 +58385,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60081,8 +58401,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60098,8 +58417,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60115,8 +58433,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60132,8 +58449,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60149,8 +58465,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60166,8 +58481,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60183,8 +58497,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60200,8 +58513,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60217,8 +58529,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60234,8 +58545,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60251,8 +58561,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60268,8 +58577,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60285,8 +58593,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60302,8 +58609,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60319,8 +58625,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60336,8 +58641,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60353,8 +58657,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60370,8 +58673,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60387,8 +58689,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60404,8 +58705,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60421,8 +58721,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60438,8 +58737,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60455,8 +58753,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60472,8 +58769,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60489,8 +58785,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60506,8 +58801,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60523,8 +58817,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -60537,8 +58830,7 @@ - s_0003: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_13BDglcn_e" - sbo: "SBO:0000627" @@ -60551,8 +58843,7 @@ - s_0002: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -60564,8 +58855,7 @@ - s_0022: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_crn_e" - sbo: "SBO:0000627" @@ -60577,8 +58867,7 @@ - s_0026: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_lac__D_e" - sbo: "SBO:0000627" @@ -60590,8 +58879,7 @@ - s_0029: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_mev__R_e" - sbo: "SBO:0000627" @@ -60603,8 +58891,7 @@ - s_0032: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pnto__R_e" - sbo: "SBO:0000627" @@ -60616,8 +58903,7 @@ - s_0036: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_btd_RR_e" - sbo: "SBO:0000627" @@ -60629,8 +58915,7 @@ - s_0058: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_3mop_e" - sbo: "SBO:0000627" @@ -60642,8 +58927,7 @@ - s_0064: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_lac__L_e" - sbo: "SBO:0000627" @@ -60656,8 +58940,7 @@ - s_0067: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_mal__L_e" - sbo: "SBO:0000627" @@ -60670,8 +58953,7 @@ - s_0080: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_g3pi_e" - sbo: "SBO:0000627" @@ -60683,8 +58965,7 @@ - s_0084: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pchol_cho_e" - sbo: "SBO:0000627" @@ -60697,8 +58978,7 @@ - s_1157: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - metanetx.reaction: "MNXR125284" - sbo: "SBO:0000655" @@ -60712,8 +58992,7 @@ - s_0127: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR101573" - sbo: "SBO:0000655" @@ -60726,8 +59005,7 @@ - s_0133: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_dad_2_e" - sbo: "SBO:0000627" @@ -60739,8 +59017,7 @@ - s_0135: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_dgsn_e" - sbo: "SBO:0000627" @@ -60752,8 +59029,7 @@ - s_0137: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_din_e" - sbo: "SBO:0000627" @@ -60765,8 +59041,7 @@ - s_0139: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_duri_e" - sbo: "SBO:0000627" @@ -60779,8 +59054,7 @@ - s_0350: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "2DDA7Ptm" - metanetx.reaction: "MNXR94782" @@ -60795,8 +59069,7 @@ - s_0150: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "2DHPtm" - metanetx.reaction: "MNXR94793" @@ -60810,8 +59083,7 @@ - s_0163: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_3c3hmp_e" - sbo: "SBO:0000627" @@ -60824,8 +59096,7 @@ - s_0163: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "3C3HMPt" - sbo: "SBO:0000655" @@ -60840,8 +59111,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKL120W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "3C3HMPtm" - sbo: "SBO:0000655" @@ -60855,8 +59125,7 @@ - s_0170: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "2MBTOHt" - metanetx.reaction: "MNXR94810" @@ -60871,8 +59140,7 @@ - s_0171: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "2MBTOHtm" - metanetx.reaction: "MNXR94810" @@ -60886,8 +59154,7 @@ - s_0167: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_2mbald_e" - sbo: "SBO:0000627" @@ -60900,8 +59167,7 @@ - s_0167: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "2MBALDt" - metanetx.reaction: "MNXR94809" @@ -60916,8 +59182,7 @@ - s_0168: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "2MBALDtm" - metanetx.reaction: "MNXR94809" @@ -60931,8 +59196,7 @@ - s_0170: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_2mbtoh_e" - sbo: "SBO:0000627" @@ -60944,8 +59208,7 @@ - s_0173: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_2mbac_e" - sbo: "SBO:0000627" @@ -60958,8 +59221,7 @@ - s_0938: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "2MPPALt" - metanetx.reaction: "MNXR94812" @@ -60974,8 +59236,7 @@ - s_0939: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "2MPPALtm" - metanetx.reaction: "MNXR94812" @@ -60991,8 +59252,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNL065W or YKL217W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "2OBUTtm" - metanetx.reaction: "MNXR94814" @@ -61006,8 +59266,7 @@ - s_0181: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_akg_e" - sbo: "SBO:0000627" @@ -61021,8 +59280,7 @@ - s_0183: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - metanetx.reaction: "MNXR95663" - sbo: "SBO:0000655" @@ -61036,8 +59294,7 @@ - s_0181: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR95663" - sbo: "SBO:0000655" @@ -61050,8 +59307,7 @@ - s_0186: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_2phetoh_e" - sbo: "SBO:0000627" @@ -61064,8 +59320,7 @@ - s_0186: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "2PHETOHt" - metanetx.reaction: "MNXR94828" @@ -61080,8 +59335,7 @@ - s_0187: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "2PHETOHtm" - metanetx.reaction: "MNXR94828" @@ -61096,8 +59350,7 @@ - s_0011: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "3C4MOPtm" - metanetx.reaction: "MNXR94859" @@ -61112,8 +59365,7 @@ - s_0060: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "3MOPtm" - metanetx.reaction: "MNXR94926" @@ -61128,8 +59380,7 @@ - s_0058: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "3MOPt" - metanetx.reaction: "MNXR94926" @@ -61143,8 +59394,7 @@ - s_0235: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_3mbald_e" - sbo: "SBO:0000627" @@ -61157,8 +59407,7 @@ - s_0235: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "3MBALDt" - metanetx.reaction: "MNXR137944" @@ -61174,8 +59423,7 @@ - s_0236: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "3MBALDtm" - metanetx.reaction: "MNXR137944" @@ -61191,8 +59439,7 @@ - s_0216: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "3OPHB_5tm" - metanetx.reaction: "MNXR94966" @@ -61206,13 +59453,12 @@ - s_0270: 1 - s_0300: -1 - s_0775: 1 - - s_0794: 1 + - s_0794: -1 - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YFL058W" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "AHMMPS" - metanetx.reaction: "MNXR95632" @@ -61227,8 +59473,7 @@ - s_0272: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_4abz_e" - sbo: "SBO:0000627" @@ -61241,8 +59486,7 @@ - s_0272: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "4ABZt" - metanetx.reaction: "MNXR94995" @@ -61257,8 +59501,7 @@ - s_0273: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "4ABZtm" - metanetx.reaction: "MNXR94995" @@ -61273,8 +59516,7 @@ - s_0275: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "4ABUTNtm" - metanetx.reaction: "MNXR94992" @@ -61289,8 +59531,7 @@ - s_0738: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "4ABUTtm" - metanetx.reaction: "MNXR94993" @@ -61305,8 +59546,7 @@ - s_0283: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "4H2OGLTtm" - metanetx.reaction: "MNXR95001" @@ -61321,8 +59561,7 @@ - s_0284: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "4H2OGLTtp" - metanetx.reaction: "MNXR95001" @@ -61337,8 +59576,7 @@ - s_0287: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "4HBZtm" - metanetx.reaction: "MNXR95013" @@ -61355,8 +59593,7 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTD7" - kegg.reaction: "R00183" @@ -61375,8 +59612,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGL101W or YBR242W" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTD6" - kegg.reaction: "R02088" @@ -61395,8 +59631,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGL101W or YBR242W" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NTD3" - kegg.reaction: "R01664" @@ -61415,8 +59650,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGL101W or YBR242W" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTD8" - kegg.reaction: "R01968" @@ -61435,8 +59669,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGL101W or YBR242W" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NTD5" - kegg.reaction: "R01569" @@ -61454,8 +59687,7 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "NTD1" - kegg.reaction: "R02102" @@ -61474,8 +59706,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER037W" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTD9" - kegg.reaction: "R01227" @@ -61494,8 +59725,7 @@ - s_1565: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTD10" - kegg.reaction: "R02719" @@ -61510,8 +59740,7 @@ - s_0316: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_5aop_e" - sbo: "SBO:0000627" @@ -61524,8 +59753,7 @@ - s_0317: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "5AOPtm" - metanetx.reaction: "MNXR95062" @@ -61544,8 +59772,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER183C" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "FTHFCLm" - kegg.reaction: "R02301" @@ -61567,8 +59794,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER183C" - - subsystem: - - "One carbon pool by folate" + - subsystem: "One carbon pool by folate" - annotation: !!omap - bigg.reaction: "FTHFI" - metanetx.reaction: "MNXR99671" @@ -61582,8 +59808,7 @@ - s_0320: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_5fthf_e" - sbo: "SBO:0000627" @@ -61595,8 +59820,7 @@ - s_0342: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_dann_e" - sbo: "SBO:0000627" @@ -61609,8 +59833,7 @@ - s_0342: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -3.1 @@ -61622,8 +59845,7 @@ - s_0354: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_8aonn_e" - sbo: "SBO:0000627" @@ -61635,8 +59857,7 @@ - s_0358: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_xan_e" - sbo: "SBO:0000627" @@ -61648,8 +59869,7 @@ - s_0360: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_acald_e" - sbo: "SBO:0000627" @@ -61662,8 +59882,7 @@ - s_0361: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ACALDtm" - metanetx.reaction: "MNXR95212" @@ -61678,8 +59897,7 @@ - s_0360: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ACALDt" - metanetx.reaction: "MNXR95212" @@ -61693,8 +59911,7 @@ - s_0364: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ac_e" - sbo: "SBO:0000627" @@ -61708,8 +59925,7 @@ - s_0366: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - metanetx.reaction: "MNXR95431" - sbo: "SBO:0000655" @@ -61723,8 +59939,7 @@ - s_0377: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "ACCOAtn" - metanetx.reaction: "MNXR95223" @@ -61739,8 +59954,7 @@ - s_1237: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "ACRNtp" - metanetx.reaction: "MNXR95412" @@ -61754,8 +59968,7 @@ - s_0384: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ade_e" - sbo: "SBO:0000627" @@ -61769,8 +59982,7 @@ - s_0385: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ADEtm" - metanetx.reaction: "MNXR95445" @@ -61784,8 +59996,7 @@ - s_0391: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pap_e" - sbo: "SBO:0000627" @@ -61799,8 +60010,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YPR011C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "PAPtm" - metanetx.reaction: "MNXR102382" @@ -61814,8 +60024,7 @@ - s_0387: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_adn_e" - sbo: "SBO:0000627" @@ -61829,8 +60038,7 @@ - s_0398: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - metanetx.reaction: "MNXR95484" - sbo: "SBO:0000655" @@ -61844,8 +60052,7 @@ - s_0395: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR95484" - sbo: "SBO:0000655" @@ -61859,8 +60066,7 @@ - s_0184: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "AKGtp" - metanetx.reaction: "MNXR95663" @@ -61874,8 +60080,7 @@ - s_0406: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_alltt_e" - sbo: "SBO:0000627" @@ -61887,8 +60092,7 @@ - s_0408: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_alltn_e" - sbo: "SBO:0000627" @@ -61901,8 +60105,7 @@ - s_1521: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_tre_e" - sbo: "SBO:0000627" @@ -61915,8 +60118,7 @@ - s_0413: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gam6p_e" - sbo: "SBO:0000627" @@ -61932,8 +60134,7 @@ - s_0181: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "AKGMAL" - metanetx.reaction: "MNXR95659" @@ -61947,8 +60148,7 @@ - s_0420: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_nh4_e" - metanetx.reaction: "MNXR101948" @@ -61963,8 +60163,7 @@ - s_0425: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "AMPtn" - metanetx.reaction: "MNXR95830" @@ -61982,8 +60181,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR147W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ARGt2m" - metanetx.reaction: "MNXR95953" @@ -62000,8 +60198,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR508C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ASNtm" - metanetx.reaction: "MNXR96069" @@ -62018,8 +60215,7 @@ - s_0995: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "ASPGLUtp" - metanetx.reaction: "MNXR96083" @@ -62034,8 +60230,7 @@ - s_0438: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "ATPtn" - metanetx.reaction: "MNXR96140" @@ -62050,8 +60245,7 @@ - s_0435: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR96140" - sbo: "SBO:0000655" @@ -62064,8 +60258,7 @@ - s_0446: -1 - lower_bound: 0 - upper_bound: 0 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_hco3_e" - metanetx.reaction: "MNXR100483" @@ -62081,8 +60274,7 @@ - s_0807: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Nitrogen metabolism" + - subsystem: "Nitrogen metabolism" - annotation: !!omap - bigg.reaction: "HCO3Em" - kegg.reaction: "R00132" @@ -62100,8 +60292,7 @@ - s_0808: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Nitrogen metabolism" + - subsystem: "Nitrogen metabolism" - annotation: !!omap - bigg.reaction: "HCO3En" - kegg.reaction: "R00132" @@ -62120,8 +60311,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNL036W" - - subsystem: - - "Nitrogen metabolism" + - subsystem: "Nitrogen metabolism" - annotation: !!omap - bigg.reaction: "HCO3E" - kegg.reaction: "R00132" @@ -62139,8 +60329,7 @@ - s_0805: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Nitrogen metabolism" + - subsystem: "Nitrogen metabolism" - annotation: !!omap - bigg.reaction: "HCO3Ee" - kegg.reaction: "R00132" @@ -62156,8 +60345,7 @@ - s_0448: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "HCO3tn" - metanetx.reaction: "MNXR100484" @@ -62171,8 +60359,7 @@ - s_0452: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_btn_e" - sbo: "SBO:0000627" @@ -62184,8 +60371,7 @@ - s_0458: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_co2_e" - sbo: "SBO:0000627" @@ -62198,8 +60384,7 @@ - s_0024: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "CRNtp" - metanetx.reaction: "MNXR96906" @@ -62216,8 +60401,7 @@ - s_1237: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "CRNCARtp" - metanetx.reaction: "MNXR96898" @@ -62232,8 +60416,7 @@ - s_0468: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "CDPtn" - metanetx.reaction: "MNXR96562" @@ -62248,8 +60431,7 @@ - s_0476: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - metanetx.reaction: "MNXR137412" - sbo: "SBO:0000655" @@ -62263,8 +60445,7 @@ - s_0482: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - metanetx.reaction: "MNXR137414" - sbo: "SBO:0000655" @@ -62278,8 +60459,7 @@ - s_0500: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 98.5 @@ -62292,8 +60472,7 @@ - s_0479: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - metanetx.reaction: "MNXR137413" - sbo: "SBO:0000655" @@ -62307,8 +60486,7 @@ - s_0485: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - metanetx.reaction: "MNXR137415" - sbo: "SBO:0000655" @@ -62322,8 +60500,7 @@ - s_0503: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 103.14 @@ -62341,8 +60518,7 @@ - s_1569: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - bigg.reaction: "CHLSTI" - metanetx.reaction: "MNXR96688" @@ -62356,8 +60532,7 @@ - s_0513: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_chol_e" - sbo: "SBO:0000627" @@ -62371,8 +60546,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YGL077C or YOR161C" - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR96693" - sbo: "SBO:0000655" @@ -62387,8 +60561,7 @@ - s_1399: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - bigg.reaction: "CHRPL" - kegg.reaction: "R01302" @@ -62404,8 +60577,7 @@ - s_0523: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR96756" - sbo: "SBO:0000655" @@ -62418,8 +60590,7 @@ - s_0523: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_cit_e" - sbo: "SBO:0000627" @@ -62435,8 +60606,7 @@ - s_0942: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "CITtcp" - metanetx.reaction: "MNXR96755" @@ -62453,8 +60623,7 @@ - s_0525: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "CITtap" - metanetx.reaction: "MNXR96753" @@ -62471,8 +60640,7 @@ - s_1408: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "CMPN" - metanetx.reaction: "MNXR96804" @@ -62487,8 +60655,7 @@ - s_0457: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "CO2ter" - metanetx.reaction: "MNXR96810" @@ -62503,8 +60670,7 @@ - s_0461: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "CO2tn" - metanetx.reaction: "MNXR96810" @@ -62519,8 +60685,7 @@ - s_0462: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "CO2tp" - metanetx.reaction: "MNXR96810" @@ -62535,8 +60700,7 @@ - s_0460: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "CO2tm" - metanetx.reaction: "MNXR96810" @@ -62551,8 +60715,7 @@ - s_0458: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CO2t" - metanetx.reaction: "MNXR96810" @@ -62567,8 +60730,7 @@ - s_0530: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "COAtr" - metanetx.reaction: "MNXR96815" @@ -62583,8 +60745,7 @@ - s_0533: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "COAtn" - metanetx.reaction: "MNXR96815" @@ -62599,8 +60760,7 @@ - s_0534: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "COAtp" - metanetx.reaction: "MNXR96815" @@ -62614,8 +60774,7 @@ - s_0544: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_cytd_e" - sbo: "SBO:0000627" @@ -62632,8 +60791,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL024C" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "CYTK1" - kegg.reaction: "R00512" @@ -62652,8 +60810,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKL024C" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "CYTK2" - kegg.reaction: "R01665" @@ -62668,8 +60825,7 @@ - s_0546: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_csn_e" - sbo: "SBO:0000627" @@ -62682,8 +60838,7 @@ - s_0549: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_arab__D_e" - sbo: "SBO:0000627" @@ -62698,8 +60853,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDR342C or YHR092C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ARAB_Dt" - sbo: "SBO:0000655" @@ -62713,8 +60867,7 @@ - s_0552: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "E4Ptm" - metanetx.reaction: "MNXR97843" @@ -62728,8 +60881,7 @@ - s_0554: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_fru_e" - sbo: "SBO:0000627" @@ -62742,8 +60894,7 @@ - s_0559: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gal_e" - kegg.reaction: "R10619" @@ -62758,8 +60909,7 @@ - s_0560: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_galur_e" - sbo: "SBO:0000627" @@ -62771,8 +60921,7 @@ - s_0562: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_sbt__D_e" - sbo: "SBO:0000627" @@ -62786,8 +60935,7 @@ - s_0413: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GAM6Pt" - sbo: "SBO:0000655" @@ -62800,8 +60948,7 @@ - s_0565: -1 - lower_bound: -1 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_glc__D_e" - metanetx.reaction: "MNXR138465" @@ -62815,8 +60962,7 @@ - s_0572: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_man_e" - sbo: "SBO:0000627" @@ -62829,8 +60975,7 @@ - s_0576: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_rib__D_e" - sbo: "SBO:0000627" @@ -62845,8 +60990,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDL245C or YEL069C or YJR158W or YNR072W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "SBT_Dt" - metanetx.reaction: "MNXR104288" @@ -62860,8 +61004,7 @@ - s_0579: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_xyl__D_e" - sbo: "SBO:0000627" @@ -62876,8 +61019,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YHR092C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "XYLt" - sbo: "SBO:0000655" @@ -62891,8 +61033,7 @@ - s_0583: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "DADPtn" - metanetx.reaction: "MNXR97082" @@ -62907,8 +61048,7 @@ - s_0588: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "DCDPtn" - metanetx.reaction: "MNXR97182" @@ -62926,8 +61066,7 @@ - s_0950: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "ATPHs" - kegg.reaction: "R00088" @@ -62946,8 +61085,7 @@ - s_0803: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "DATPHs" - metanetx.reaction: "MNXR97174" @@ -62965,8 +61103,7 @@ - s_0846: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - kegg.reaction: "R00123" - metanetx.reaction: "MNXR106399" @@ -62984,8 +61121,7 @@ - s_0803: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 3.94 @@ -62998,8 +61134,7 @@ - s_0593: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "DNADtn" - metanetx.reaction: "MNXR97625" @@ -63013,8 +61148,7 @@ - s_0597: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_dca_e" - sbo: "SBO:0000627" @@ -63028,8 +61162,7 @@ - s_0133: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "DADNt4" - metanetx.reaction: "MNXR97081" @@ -63047,8 +61180,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDL166C" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "DADK" - kegg.reaction: "R01547" @@ -63063,8 +61195,7 @@ - s_0611: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_dcyt_e" - sbo: "SBO:0000627" @@ -63077,8 +61208,7 @@ - s_0611: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "DCYTt" - metanetx.reaction: "MNXR97208" @@ -63093,8 +61223,7 @@ - s_0135: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "DGSNt" - metanetx.reaction: "MNXR97324" @@ -63109,8 +61238,7 @@ - s_0137: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "DINt" - metanetx.reaction: "MNXR97466" @@ -63128,8 +61256,7 @@ - s_0794: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "DURIK1" - kegg.reaction: "R02099" @@ -63146,8 +61273,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBL042C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "DURIt" - metanetx.reaction: "MNXR97819" @@ -63166,8 +61292,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR196C" - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "DPCOAK" - kegg.reaction: "R00130" @@ -63183,8 +61308,7 @@ - s_0614: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "DGDPtn" - metanetx.reaction: "MNXR97314" @@ -63199,8 +61323,7 @@ - s_0344: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "DHNPTtm" - sbo: "SBO:0000655" @@ -63218,8 +61341,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR071C" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "DIAT" - metanetx.reaction: "MNXR97455" @@ -63234,8 +61356,7 @@ - s_0626: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "DHFtm" - metanetx.reaction: "MNXR97404" @@ -63253,8 +61374,7 @@ - s_0803: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - bigg.reaction: "DNTPPA" - kegg.reaction: "R04638" @@ -63270,8 +61390,7 @@ - s_0348: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "DHPTtm" - metanetx.reaction: "MNXR142733" @@ -63287,8 +61406,7 @@ - s_0632: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "DHAPtm" - metanetx.reaction: "MNXR97366" @@ -63304,8 +61422,7 @@ - s_0638: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "PPItx" - metanetx.reaction: "MNXR103112" @@ -63320,8 +61437,7 @@ - s_0646: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "DOLP_ter" - sbo: "SBO:0000655" @@ -63334,8 +61450,7 @@ - s_0651: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_dttp_e" - sbo: "SBO:0000627" @@ -63348,8 +61463,7 @@ - s_0651: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "DTTPt" - metanetx.reaction: "MNXR97810" @@ -63364,8 +61478,7 @@ - s_0653: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "DUDPtn" - metanetx.reaction: "MNXR97812" @@ -63380,8 +61493,7 @@ - s_0655: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "DUMPtn" - metanetx.reaction: "MNXR97813" @@ -63395,8 +61507,7 @@ - s_0659: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_epist_e" - sbo: "SBO:0000627" @@ -63409,8 +61520,7 @@ - s_0663: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "ERGTETROLter" - metanetx.reaction: "MNXR97951" @@ -63424,8 +61534,7 @@ - s_0668: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ergst_e" - sbo: "SBO:0000627" @@ -63438,8 +61547,7 @@ - s_0667: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "ERGSTter" - metanetx.reaction: "MNXR97950" @@ -63454,8 +61562,7 @@ - s_0669: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR97950" - sbo: "SBO:0000655" @@ -63468,8 +61575,7 @@ - s_0681: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_etoh_e" - sbo: "SBO:0000627" @@ -63483,8 +61589,7 @@ - s_0681: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ETOHt" - metanetx.reaction: "MNXR97980" @@ -63499,8 +61604,7 @@ - s_0682: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ETOHtm" - metanetx.reaction: "MNXR97980" @@ -63514,8 +61618,7 @@ - s_0684: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_etha_e" - sbo: "SBO:0000627" @@ -63527,8 +61630,7 @@ - s_0686: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -63540,8 +61642,7 @@ - s_0191: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "FRDPtm" - metanetx.reaction: "MNXR99646" @@ -63557,8 +61658,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "FA100tp" - metanetx.reaction: "MNXR135772" @@ -63574,8 +61674,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "FA120tp" - metanetx.reaction: "MNXR135773" @@ -63591,8 +61690,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "FA140tp" - metanetx.reaction: "MNXR128297" @@ -63608,8 +61706,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "FA160tp" - metanetx.reaction: "MNXR99101" @@ -63625,8 +61722,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "FA161tp" - sbo: "SBO:0000655" @@ -63640,8 +61736,7 @@ - s_1253: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "FA80tp" - metanetx.reaction: "MNXR99126" @@ -63656,8 +61751,7 @@ - s_1163: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "TTDCAtr" - metanetx.reaction: "MNXR128297" @@ -63671,8 +61765,7 @@ - s_0702: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_fecost_e" - sbo: "SBO:0000627" @@ -63689,8 +61782,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDL045C" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "FMNATm" - kegg.reaction: "R00161" @@ -63705,8 +61797,7 @@ - s_0715: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_fmn_e" - sbo: "SBO:0000627" @@ -63718,8 +61809,7 @@ - s_0720: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_fol_e" - sbo: "SBO:0000627" @@ -63731,8 +61821,7 @@ - s_0723: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_for_e" - sbo: "SBO:0000627" @@ -63746,8 +61835,7 @@ - s_0724: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "FORtm" - metanetx.reaction: "MNXR99620" @@ -63763,8 +61851,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNL065W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "FORt" - metanetx.reaction: "MNXR99620" @@ -63779,8 +61866,7 @@ - s_0726: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "FUMtr" - metanetx.reaction: "MNXR99715" @@ -63798,8 +61884,7 @@ - s_0794: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - bigg.reaction: "FRUK" - sbo: "SBO:0000176" @@ -63812,8 +61897,7 @@ - s_0726: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_fum_e" - sbo: "SBO:0000627" @@ -63826,8 +61910,7 @@ - s_0736: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_4abut_e" - sbo: "SBO:0000627" @@ -63841,8 +61924,7 @@ - s_0740: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - bigg.reaction: "GDPtg" - metanetx.reaction: "MNXR100096" @@ -63857,8 +61939,7 @@ - s_0742: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "GDPtn" - metanetx.reaction: "MNXR100096" @@ -63874,8 +61955,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YGL225W" - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - metanetx.reaction: "MNXR131177" - sbo: "SBO:0000655" @@ -63890,8 +61970,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR241C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "GLCtv" - metanetx.reaction: "MNXR100188" @@ -63905,8 +61984,7 @@ - s_0755: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gthox_e" - sbo: "SBO:0000627" @@ -63918,8 +61996,7 @@ - s_0751: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gthrd_e" - sbo: "SBO:0000627" @@ -63932,8 +62009,7 @@ - s_0766: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_glyc_e" - sbo: "SBO:0000627" @@ -63947,8 +62023,7 @@ - s_0770: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "GLYC3Ptm" - metanetx.reaction: "MNXR100308" @@ -63963,8 +62038,7 @@ - s_1004: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gly_e" - sbo: "SBO:0000627" @@ -63979,8 +62053,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YPR058W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "GLYtm" - metanetx.reaction: "MNXR100371" @@ -63995,8 +62068,7 @@ - s_0777: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "GCALDtm" - metanetx.reaction: "MNXR100061" @@ -64011,8 +62083,7 @@ - s_0776: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GCALDt" - metanetx.reaction: "MNXR100061" @@ -64026,8 +62097,7 @@ - s_0776: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gcald_e" - sbo: "SBO:0000627" @@ -64039,8 +62109,7 @@ - s_0780: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_glx_e" - sbo: "SBO:0000627" @@ -64055,8 +62124,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNL065W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GLXt" - metanetx.reaction: "MNXR100306" @@ -64071,8 +62139,7 @@ - s_0781: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "GLXtp" - metanetx.reaction: "MNXR100306" @@ -64086,8 +62153,7 @@ - s_0788: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gua_e" - sbo: "SBO:0000627" @@ -64101,8 +62167,7 @@ - s_0789: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "GUAtm" - metanetx.reaction: "MNXR100465" @@ -64116,8 +62181,7 @@ - s_0791: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gsn_e" - sbo: "SBO:0000627" @@ -64134,8 +62198,7 @@ - s_0794: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "GSNK" - kegg.reaction: "R01228" @@ -64151,8 +62214,7 @@ - s_0792: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "GSNtm" - metanetx.reaction: "MNXR100433" @@ -64167,8 +62229,7 @@ - s_0791: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GSNt" - metanetx.reaction: "MNXR100433" @@ -64183,8 +62244,7 @@ - s_0796: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "Ht" - metanetx.reaction: "MNXR100765" @@ -64199,8 +62259,7 @@ - s_0795: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "Htr" - metanetx.reaction: "MNXR100765" @@ -64215,8 +62274,7 @@ - s_0797: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - bigg.reaction: "Htg" - metanetx.reaction: "MNXR100765" @@ -64231,8 +62289,7 @@ - s_0798: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR100765" - sbo: "SBO:0000655" @@ -64246,8 +62303,7 @@ - s_0800: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "HMR_1095" - metanetx.reaction: "MNXR100765" @@ -64262,8 +62318,7 @@ - s_0801: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "Htx" - metanetx.reaction: "MNXR100765" @@ -64278,8 +62333,7 @@ - s_0802: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR100765" - sbo: "SBO:0000655" @@ -64292,8 +62346,7 @@ - s_0796: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_h_e" - sbo: "SBO:0000627" @@ -64306,8 +62359,7 @@ - s_0817: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR124347" - sbo: "SBO:0000655" @@ -64320,8 +62372,7 @@ - s_0826: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -64334,8 +62385,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "HDCAt" - metanetx.reaction: "MNXR99101" @@ -64351,8 +62401,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "HDCEAt" - sbo: "SBO:0000655" @@ -64367,8 +62416,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR147W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - metanetx.reaction: "MNXR100649" - sbo: "SBO:0000655" @@ -64388,8 +62436,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL131W or YDL182W" - eccodes: "2.3.3.14" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - kegg.pathway: - "sce00300" @@ -64411,8 +62458,7 @@ - s_0839: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "H2O2tn" - metanetx.reaction: "MNXR98640" @@ -64427,8 +62473,7 @@ - s_0221: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "HMGCOAtm" - metanetx.reaction: "MNXR100661" @@ -64442,8 +62487,7 @@ - s_0844: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_hxan_e" - sbo: "SBO:0000627" @@ -64456,8 +62500,7 @@ - s_0844: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "HYXNt" - metanetx.reaction: "MNXR100749" @@ -64471,8 +62514,7 @@ - s_0851: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_id3acald_e" - sbo: "SBO:0000627" @@ -64485,8 +62527,7 @@ - s_0852: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ID3ACALDtm" - metanetx.reaction: "MNXR100791" @@ -64501,8 +62542,7 @@ - s_0851: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ID3ACALDt" - metanetx.reaction: "MNXR100791" @@ -64517,8 +62557,7 @@ - s_0854: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "IND3ACtm" - metanetx.reaction: "MNXR100833" @@ -64532,8 +62571,7 @@ - s_0857: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ins_e" - sbo: "SBO:0000627" @@ -64547,8 +62585,7 @@ - s_0857: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "INSt" - metanetx.reaction: "MNXR100849" @@ -64563,8 +62600,7 @@ - s_1159: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "MINOHPtn" - metanetx.reaction: "MNXR101585" @@ -64582,8 +62618,7 @@ - s_0856: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "INSK" - kegg.reaction: "R01131" @@ -64599,8 +62634,7 @@ - s_0895: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 110.09 @@ -64613,8 +62647,7 @@ - s_0901: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 110.09 @@ -64627,8 +62660,7 @@ - s_0907: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 110.09 @@ -64641,8 +62673,7 @@ - s_0913: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 110.09 @@ -64655,8 +62686,7 @@ - s_0919: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 110.09 @@ -64669,8 +62699,7 @@ - s_0898: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 114.72 @@ -64683,8 +62712,7 @@ - s_0904: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 114.72 @@ -64697,8 +62725,7 @@ - s_0910: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 114.72 @@ -64711,8 +62738,7 @@ - s_0916: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 114.72 @@ -64725,8 +62751,7 @@ - s_0922: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 114.72 @@ -64738,8 +62763,7 @@ - s_0925: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_fe2_e" - sbo: "SBO:0000627" @@ -64751,8 +62775,7 @@ - s_0928: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_iamac_e" - sbo: "SBO:0000627" @@ -64765,8 +62788,7 @@ - s_0930: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "IAMOHt" - metanetx.reaction: "MNXR100775" @@ -64781,8 +62803,7 @@ - s_0931: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "IAMOHtm" - metanetx.reaction: "MNXR100775" @@ -64796,8 +62817,7 @@ - s_0930: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_iamoh_e" - sbo: "SBO:0000627" @@ -64809,8 +62829,7 @@ - s_0933: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ibutoh_e" - sbo: "SBO:0000627" @@ -64822,8 +62841,7 @@ - s_0936: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ibutac_e" - sbo: "SBO:0000627" @@ -64836,8 +62854,7 @@ - s_0933: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "IBUTOHt" - metanetx.reaction: "MNXR100780" @@ -64852,8 +62869,7 @@ - s_0934: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "IBUTOHtm" - metanetx.reaction: "MNXR100780" @@ -64867,8 +62883,7 @@ - s_0938: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_2mppal_e" - sbo: "SBO:0000627" @@ -64883,8 +62898,7 @@ - s_0954: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "PHCHGSm" - sbo: "SBO:0000176" @@ -64900,8 +62914,7 @@ - s_0952: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "AOBUTDs" - kegg.reaction: "R03758" @@ -64916,8 +62929,7 @@ - s_0956: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ala__L_e" - sbo: "SBO:0000627" @@ -64931,8 +62943,7 @@ - s_0957: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ALAtmi" - metanetx.reaction: "MNXR95706" @@ -64946,8 +62957,7 @@ - s_0962: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_abt_e" - sbo: "SBO:0000627" @@ -64961,8 +62971,7 @@ - s_0962: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ABTt" - metanetx.reaction: "MNXR95190" @@ -64978,8 +62987,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDR342C or YHR092C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ARAB_Lt" - metanetx.reaction: "MNXR135734" @@ -64993,8 +63001,7 @@ - s_0964: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_arab__L_e" - sbo: "SBO:0000627" @@ -65007,8 +63014,7 @@ - s_0966: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_arg__L_e" - sbo: "SBO:0000627" @@ -65021,8 +63027,7 @@ - s_0970: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_asn__L_e" - sbo: "SBO:0000627" @@ -65035,8 +63040,7 @@ - s_0974: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_asp__L_e" - sbo: "SBO:0000627" @@ -65051,8 +63055,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOR100C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "CRNtim" - metanetx.reaction: "MNXR96906" @@ -65066,8 +63069,7 @@ - s_0982: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_cys__L_e" - sbo: "SBO:0000627" @@ -65081,8 +63083,7 @@ - s_0678: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "E4HGLUtm" - metanetx.reaction: "MNXR97841" @@ -65097,8 +63098,7 @@ - s_0679: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "E4HGLUtp" - metanetx.reaction: "MNXR97841" @@ -65112,8 +63112,7 @@ - s_0990: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_sbt__L_e" - sbo: "SBO:0000627" @@ -65128,8 +63127,7 @@ - s_0997: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "G5SADs" - kegg.reaction: "R03314" @@ -65144,8 +63142,7 @@ - s_0992: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_glu__L_e" - sbo: "SBO:0000627" @@ -65159,8 +63156,7 @@ - s_0994: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - metanetx.reaction: "MNXR100301" - sbo: "SBO:0000655" @@ -65173,8 +63169,7 @@ - s_1000: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gln__L_e" - sbo: "SBO:0000627" @@ -65188,8 +63183,7 @@ - s_1001: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - metanetx.reaction: "MNXR100259" - sbo: "SBO:0000655" @@ -65202,8 +63196,7 @@ - s_1007: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_his__L_e" - sbo: "SBO:0000627" @@ -65216,8 +63209,7 @@ - s_1015: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "r2535" - metanetx.reaction: "MNXR100678" @@ -65231,8 +63223,7 @@ - s_1015: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_hom__L_e" - sbo: "SBO:0000627" @@ -65245,8 +63236,7 @@ - s_1017: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ile__L_e" - sbo: "SBO:0000627" @@ -65260,8 +63250,7 @@ - s_1018: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ILEtmi" - metanetx.reaction: "MNXR100824" @@ -65275,8 +63264,7 @@ - s_1022: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_leu__L_e" - sbo: "SBO:0000627" @@ -65289,8 +63277,7 @@ - s_1026: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_lys__L_e" - sbo: "SBO:0000627" @@ -65303,8 +63290,7 @@ - s_0067: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "MALt" - metanetx.reaction: "MNXR101367" @@ -65318,8 +63304,7 @@ - s_1030: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_met__L_e" - sbo: "SBO:0000627" @@ -65332,8 +63317,7 @@ - s_1033: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_phe__L_e" - sbo: "SBO:0000627" @@ -65346,8 +63330,7 @@ - s_1036: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pro__L_e" - sbo: "SBO:0000627" @@ -65361,8 +63344,7 @@ - s_1037: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "PROtm" - metanetx.reaction: "MNXR103213" @@ -65376,8 +63358,7 @@ - s_1041: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ser__L_e" - sbo: "SBO:0000627" @@ -65392,8 +63373,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKR039W" - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR104354" - sbo: "SBO:0000655" @@ -65408,8 +63388,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDL245C or YEL069C or YJR158W or YNR072W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "SBT_Lt" - metanetx.reaction: "MNXR104289" @@ -65423,8 +63402,7 @@ - s_1044: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_srb__L_e" - sbo: "SBO:0000627" @@ -65438,8 +63416,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDL245C or YDR342C or YDR343C or YDR345C or YEL069C or YFL011W or YHR092C or YHR096C or YJL214W or YJL219W or YJR158W or YNR072W or YOL156W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "SRB_Lt" - metanetx.reaction: "MNXR104533" @@ -65453,8 +63430,7 @@ - s_1046: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_thr__L_e" - sbo: "SBO:0000627" @@ -65467,8 +63443,7 @@ - s_1049: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_trp__L_e" - sbo: "SBO:0000627" @@ -65481,8 +63456,7 @@ - s_1052: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_tyr__L_e" - sbo: "SBO:0000627" @@ -65495,8 +63469,7 @@ - s_1057: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_val__L_e" - sbo: "SBO:0000627" @@ -65509,8 +63482,7 @@ - s_1061: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_lanost_e" - sbo: "SBO:0000627" @@ -65522,8 +63494,7 @@ - s_1067: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ddca_e" - sbo: "SBO:0000627" @@ -65537,8 +63508,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YBR147W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - metanetx.reaction: "MNXR101269" - sbo: "SBO:0000655" @@ -65552,8 +63522,7 @@ - s_0862: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 133.27 @@ -65566,8 +63535,7 @@ - s_0868: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 133.27 @@ -65580,8 +63548,7 @@ - s_0874: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 133.27 @@ -65594,8 +63561,7 @@ - s_0880: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 133.27 @@ -65608,8 +63574,7 @@ - s_0886: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 133.27 @@ -65622,8 +63587,7 @@ - s_0865: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 137.9 @@ -65636,8 +63600,7 @@ - s_0871: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 137.9 @@ -65650,8 +63613,7 @@ - s_0877: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 137.9 @@ -65664,8 +63626,7 @@ - s_0883: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 137.9 @@ -65678,8 +63639,7 @@ - s_0889: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 137.9 @@ -65694,8 +63654,7 @@ - s_1274: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "MALOAAtp" - metanetx.reaction: "MNXR101346" @@ -65709,8 +63668,7 @@ - s_1106: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_malt_e" - metanetx.reaction: "MNXR123950" @@ -65725,8 +63683,7 @@ - s_1108: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "MANNANter" - metanetx.reaction: "MNXR101396" @@ -65742,8 +63699,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR508C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "METtm" - metanetx.reaction: "MNXR101493" @@ -65759,8 +63715,7 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Propanoate metabolism" + - subsystem: "Propanoate metabolism" - annotation: !!omap - bigg.reaction: "MGSA" - kegg.reaction: "R01016" @@ -65776,8 +63731,7 @@ - s_1117: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 121.68 @@ -65790,8 +63744,7 @@ - s_1123: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 121.68 @@ -65804,8 +63757,7 @@ - s_1129: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 121.68 @@ -65818,8 +63770,7 @@ - s_1135: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 121.68 @@ -65832,8 +63783,7 @@ - s_1141: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 121.68 @@ -65846,8 +63796,7 @@ - s_1120: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 126.31 @@ -65860,8 +63809,7 @@ - s_1126: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 126.31 @@ -65874,8 +63822,7 @@ - s_1132: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 126.31 @@ -65888,8 +63835,7 @@ - s_1138: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 126.31 @@ -65902,8 +63848,7 @@ - s_1144: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 126.31 @@ -65915,8 +63860,7 @@ - s_1154: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_inost_e" - sbo: "SBO:0000627" @@ -65928,8 +63872,7 @@ - s_1186: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -65941,8 +63884,7 @@ - s_1208: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "NADPtru" - metanetx.reaction: "MNXR101896" @@ -65957,8 +63899,7 @@ - s_1213: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "NADPHtru" - metanetx.reaction: "MNXR101894" @@ -65973,8 +63914,7 @@ - s_0421: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "NH4tm" - metanetx.reaction: "MNXR101950" @@ -65989,8 +63929,7 @@ - s_1217: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - metanetx.reaction: "MNXR101918" - sbo: "SBO:0000655" @@ -66003,8 +63942,7 @@ - s_1220: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_nac_e" - sbo: "SBO:0000627" @@ -66016,8 +63954,7 @@ - s_1225: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_nmn_e" - sbo: "SBO:0000627" @@ -66030,8 +63967,7 @@ - s_1227: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "NMNtn" - metanetx.reaction: "MNXR101972" @@ -66046,8 +63982,7 @@ - s_1228: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - metanetx.reaction: "MNXR101972" - sbo: "SBO:0000655" @@ -66061,8 +63996,7 @@ - s_1225: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "NMNP" - metanetx.reaction: "MNXR101972" @@ -66080,8 +64014,7 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NDP4" - metanetx.reaction: "MNXR101929" @@ -66099,8 +64032,7 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTP4" - metanetx.reaction: "MNXR102044" @@ -66116,8 +64048,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOR100C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ACRNtm" - metanetx.reaction: "MNXR95412" @@ -66132,8 +64063,7 @@ - s_1276: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "O2ter" - metanetx.reaction: "MNXR102090" @@ -66148,8 +64078,7 @@ - s_1278: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "O2tm" - metanetx.reaction: "MNXR102090" @@ -66164,8 +64093,7 @@ - s_1277: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "O2t" - metanetx.reaction: "MNXR102090" @@ -66180,8 +64108,7 @@ - s_1279: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "O2tp" - metanetx.reaction: "MNXR102090" @@ -66197,8 +64124,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "OCDCAt" - metanetx.reaction: "MNXR99109" @@ -66212,8 +64138,7 @@ - s_1250: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_octa_e" - sbo: "SBO:0000627" @@ -66225,8 +64150,7 @@ - s_1267: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_orn_e" - sbo: "SBO:0000627" @@ -66240,8 +64164,7 @@ - s_1272: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "OAAt" - metanetx.reaction: "MNXR102100" @@ -66255,8 +64178,7 @@ - s_1272: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_oaa_e" - kegg.reaction: "R00363" @@ -66273,8 +64195,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJL212C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GTHOXti" - metanetx.reaction: "MNXR100443" @@ -66289,8 +64210,7 @@ - s_1623: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "TRDOXtp" - metanetx.reaction: "MNXR104921" @@ -66304,8 +64224,7 @@ - s_1277: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_o2_e" - sbo: "SBO:0000627" @@ -66317,8 +64236,7 @@ - s_1288: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_hdca_e" - sbo: "SBO:0000627" @@ -66330,8 +64248,7 @@ - s_1295: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_hdcea_e" - sbo: "SBO:0000627" @@ -66344,8 +64261,7 @@ - s_1303: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "PMTCOAFABP1tc" - metanetx.reaction: "MNXR103046" @@ -66360,8 +64276,7 @@ - s_1308: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "PAN4Ptm" - metanetx.reaction: "MNXR102344" @@ -66379,8 +64294,7 @@ - s_1308: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Pantothenate and coa biosynthesis" + - subsystem: "Pantothenate and coa biosynthesis" - annotation: !!omap - bigg.reaction: "PTPATim" - kegg.reaction: "R03035" @@ -66396,8 +64310,7 @@ - s_0391: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PAPt" - metanetx.reaction: "MNXR102382" @@ -66411,8 +64324,7 @@ - s_1309: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pectin_e" - sbo: "SBO:0000627" @@ -66424,8 +64336,7 @@ - s_1317: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pheac_e" - sbo: "SBO:0000627" @@ -66437,8 +64348,7 @@ - s_1319: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pacald_e" - sbo: "SBO:0000627" @@ -66451,8 +64361,7 @@ - s_1319: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PACALDt" - metanetx.reaction: "MNXR102312" @@ -66467,8 +64376,7 @@ - s_1320: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "PACALDtm" - metanetx.reaction: "MNXR102312" @@ -66483,8 +64391,7 @@ - s_1034: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - metanetx.reaction: "MNXR102637" - sbo: "SBO:0000655" @@ -66497,8 +64404,7 @@ - s_1324: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pi_e" - sbo: "SBO:0000627" @@ -66513,8 +64419,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNR013C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR102871" - sbo: "SBO:0000655" @@ -66527,8 +64432,7 @@ - s_1374: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_k_e" - sbo: "SBO:0000627" @@ -66541,8 +64445,7 @@ - s_1385: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "PPPG9tm" - metanetx.reaction: "MNXR103127" @@ -66557,8 +64460,7 @@ - s_1387: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "PRPPtm" - metanetx.reaction: "MNXR103216" @@ -66572,8 +64474,7 @@ - s_1390: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ptrc_e" - sbo: "SBO:0000627" @@ -66590,8 +64491,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YNR027W" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "PYDXK" - kegg.reaction: "R00174" @@ -66611,8 +64511,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YNR027W" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "PYDAMK" - kegg.reaction: "R02493" @@ -66630,8 +64529,7 @@ - s_1395: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "HYPOE" - kegg.reaction: "R02494" @@ -66646,8 +64544,7 @@ - s_1397: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pydxn_e" - sbo: "SBO:0000627" @@ -66665,8 +64562,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL029C" - eccodes: "2.7.1.35" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "PYDXNK" - kegg.pathway: "sce00750" @@ -66685,8 +64581,7 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "PMDPHT" - kegg.reaction: "R07280" @@ -66704,8 +64599,7 @@ - s_1556: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "PYNP2r" - kegg.reaction: "R01876" @@ -66721,8 +64615,7 @@ - s_0636: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "PPItm" - metanetx.reaction: "MNXR103112" @@ -66736,8 +64629,7 @@ - s_1400: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pyr_e" - sbo: "SBO:0000627" @@ -66754,8 +64646,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "(YGL080W and YGR243W) or (YGL080W and YHR162W)" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "PYRt2m" - metanetx.reaction: "MNXR103385" @@ -66771,8 +64662,7 @@ - s_1404: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "QULNtm" - metanetx.reaction: "MNXR103401" @@ -66787,8 +64677,7 @@ - s_1619: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "TRDRDtp" - sbo: "SBO:0000655" @@ -66801,8 +64690,7 @@ - s_1406: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ribflv_e" - sbo: "SBO:0000627" @@ -66815,8 +64703,7 @@ - s_1407: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "RIBFLVtm" - metanetx.reaction: "MNXR104033" @@ -66832,8 +64719,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOR306C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "r1106" - metanetx.reaction: "MNXR104033" @@ -66849,8 +64735,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR342C or YHR092C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "RIBt" - metanetx.reaction: "MNXR104036" @@ -66865,8 +64750,7 @@ - s_1415: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "AHCYStm" - metanetx.reaction: "MNXR95626" @@ -66880,8 +64764,7 @@ - s_1418: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_amet_e" - sbo: "SBO:0000627" @@ -66893,8 +64776,7 @@ - s_1425: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_mmet_e" - sbo: "SBO:0000627" @@ -66908,8 +64790,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDR508C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "r1435" - metanetx.reaction: "MNXR104354" @@ -66923,8 +64804,7 @@ - s_1435: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_g3pc_e" - sbo: "SBO:0000627" @@ -66936,8 +64816,7 @@ - s_1438: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_na1_e" - sbo: "SBO:0000627" @@ -66953,8 +64832,7 @@ - s_1439: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "SPMDAT1" - metanetx.reaction: "MNXR104491" @@ -66968,8 +64846,7 @@ - s_1440: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_spmd_e" - sbo: "SBO:0000627" @@ -66981,8 +64858,7 @@ - s_1443: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_sprm_e" - sbo: "SBO:0000627" @@ -66995,8 +64871,7 @@ - s_1448: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "SQLter" - metanetx.reaction: "MNXR104530" @@ -67011,8 +64886,7 @@ - s_0038: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "SQ23EPXter" - metanetx.reaction: "MNXR104505" @@ -67026,8 +64900,7 @@ - s_1450: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ocdca_e" - sbo: "SBO:0000627" @@ -67039,8 +64912,7 @@ - s_1459: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_succ_e" - sbo: "SBO:0000627" @@ -67054,8 +64926,7 @@ - s_1459: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "SUCCt" - metanetx.reaction: "MNXR104619" @@ -67069,8 +64940,7 @@ - s_1466: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_sucr_e" - sbo: "SBO:0000627" @@ -67083,8 +64953,7 @@ - s_1468: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_so4_e" - sbo: "SBO:0000627" @@ -67097,8 +64966,7 @@ - s_1470: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_so3_e" - metanetx.reaction: "MNXR122251" @@ -67111,8 +64979,7 @@ - s_1472: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_taur_e" - sbo: "SBO:0000627" @@ -67125,8 +64992,7 @@ - s_1480: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR137463" - sbo: "SBO:0000655" @@ -67143,8 +65009,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDL024C" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "THMP" - kegg.reaction: "R02135" @@ -67163,8 +65028,7 @@ - s_1489: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "TMN" - kegg.reaction: "R02133" @@ -67179,8 +65043,7 @@ - s_1476: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_thmpp_e" - sbo: "SBO:0000627" @@ -67192,8 +65055,7 @@ - s_1490: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_thm_e" - sbo: "SBO:0000627" @@ -67205,8 +65067,7 @@ - s_1498: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_thmmp_e" - sbo: "SBO:0000627" @@ -67221,8 +65082,7 @@ - s_1497: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - bigg.reaction: "TMPK" - kegg.reaction: "R00617" @@ -67239,8 +65099,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR508C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "thr_mt" - metanetx.reaction: "MNXR104852" @@ -67254,8 +65113,7 @@ - s_1494: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_thymd_e" - sbo: "SBO:0000627" @@ -67271,8 +65129,7 @@ - s_1493: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "TMDK1" - kegg.reaction: "R01567" @@ -67288,8 +65145,7 @@ - s_1494: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "THYMDt1" - metanetx.reaction: "MNXR104821" @@ -67305,10 +65161,9 @@ - s_1520: -1 - s_1521: 1 - lower_bound: -1000 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YGR289C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "TREt2" - metanetx.reaction: "MNXR104932" @@ -67324,8 +65179,7 @@ - s_1522: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR104933" - sbo: "SBO:0000655" @@ -67339,8 +65193,7 @@ - s_1050: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - metanetx.reaction: "MNXR104949" - sbo: "SBO:0000655" @@ -67353,8 +65206,7 @@ - s_1530: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ind3eth_e" - sbo: "SBO:0000627" @@ -67367,8 +65219,7 @@ - s_1530: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "IND3ETHt" - metanetx.reaction: "MNXR100834" @@ -67383,8 +65234,7 @@ - s_1531: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "IND3ETHtm" - metanetx.reaction: "MNXR100834" @@ -67399,8 +65249,7 @@ - s_1053: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "r1078" - metanetx.reaction: "MNXR105002" @@ -67415,8 +65264,7 @@ - s_1054: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - metanetx.reaction: "MNXR105002" - sbo: "SBO:0000655" @@ -67430,8 +65278,7 @@ - s_1548: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "UMPtn" - metanetx.reaction: "MNXR105127" @@ -67445,8 +65292,7 @@ - s_1551: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ura_e" - sbo: "SBO:0000627" @@ -67458,8 +65304,7 @@ - s_1553: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_urea_e" - sbo: "SBO:0000627" @@ -67472,8 +65317,7 @@ - s_1557: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_uri_e" - sbo: "SBO:0000627" @@ -67486,8 +65330,7 @@ - s_1058: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "VALt5m" - metanetx.reaction: "MNXR105190" @@ -67503,8 +65346,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YLL052C or YPR192W" - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "H2Oter" - metanetx.reaction: "MNXR98641" @@ -67519,8 +65361,7 @@ - s_0806: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - bigg.reaction: "H2Otg" - metanetx.reaction: "MNXR98641" @@ -67535,8 +65376,7 @@ - s_0807: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "H2Otm" - metanetx.reaction: "MNXR98641" @@ -67551,8 +65391,7 @@ - s_0808: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "H2Otn" - metanetx.reaction: "MNXR98641" @@ -67567,8 +65406,7 @@ - s_0809: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "H2Otp" - metanetx.reaction: "MNXR98641" @@ -67583,8 +65421,7 @@ - s_0810: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - bigg.reaction: "H2Otv" - metanetx.reaction: "MNXR98641" @@ -67598,8 +65435,7 @@ - s_0805: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_h2o_e" - sbo: "SBO:0000627" @@ -67612,8 +65448,7 @@ - s_0358: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "XANt" - metanetx.reaction: "MNXR105226" @@ -67627,8 +65462,7 @@ - s_1564: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_xtsn_e" - sbo: "SBO:0000627" @@ -67641,8 +65475,7 @@ - s_1564: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "XTSNtr" - metanetx.reaction: "MNXR105247" @@ -67656,8 +65489,7 @@ - s_1567: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_xylt_e" - sbo: "SBO:0000627" @@ -67672,8 +65504,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDL245C or YLL043W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "XYLTt" - metanetx.reaction: "MNXR105264" @@ -67687,8 +65518,7 @@ - s_1571: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_zymst_e" - sbo: "SBO:0000627" @@ -67702,8 +65532,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL013C or YOR011W" - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR105285" - sbo: "SBO:0000655" @@ -67718,8 +65547,7 @@ - s_3747: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Growth" + - subsystem: "Growth" - annotation: !!omap - pubmed: "18687109" - sbo: "SBO:0000395" @@ -67734,8 +65562,7 @@ - lower_bound: 0 - upper_bound: 1000 - objective_coefficient: 1 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - metanetx.reaction: "MNXR137261" - sbo: "SBO:0000632" @@ -67754,8 +65581,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL060W" - eccodes: "2.6.1.7" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - kegg.pathway: "sce00380" - kegg.reaction: "R01959" @@ -67777,8 +65603,7 @@ - s_2764: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - kegg.reaction: "R03687" - metanetx.reaction: "MNXR108341" @@ -67797,8 +65622,7 @@ - s_1403: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - kegg.reaction: "R04293" - metanetx.reaction: "MNXR103396" @@ -67820,8 +65644,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR145W or YOL086C" - eccodes: "1.1.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "ALCD2ir" - kegg.pathway: @@ -67850,8 +65673,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C or YMR170C or YER073W or YOR374W" - eccodes: "1.2.1.3" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -67880,8 +65702,7 @@ - eccodes: - "2.6.1.58" - "2.6.1.7" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00350" @@ -67912,8 +65733,7 @@ - eccodes: - "2.6.1.57" - "2.6.1.7" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - bigg.reaction: "araphe3" - kegg.pathway: @@ -67944,8 +65764,7 @@ - eccodes: - "2.6.1.57" - "2.6.1.7" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" + - subsystem: "Phenylalanine, tyrosine and tryptophan biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00350" @@ -67969,8 +65788,7 @@ - s_0531: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - kegg.reaction: "R00197" - metanetx.reaction: "MNXR138960" @@ -67991,8 +65809,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR043C" - eccodes: "3.1.3.37" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -68018,8 +65835,7 @@ - s_0799: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "Htm" - metanetx.reaction: "MNXR100765" @@ -68040,8 +65856,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL066W" - eccodes: "1.1.1.42" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "ICDHym" - kegg.pathway: @@ -68072,8 +65887,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOR222W or YPL134C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "AKGMALtm" - metanetx.reaction: "MNXR95659" @@ -68088,8 +65902,7 @@ - s_2766: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -68101,8 +65914,7 @@ - s_2766: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137169" - sbo: "SBO:0000655" @@ -68115,8 +65927,7 @@ - s_2768: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -68128,8 +65939,7 @@ - s_2768: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR97951" - sbo: "SBO:0000655" @@ -68152,8 +65962,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL182W and YPL231W" - eccodes: "2.3.1.86" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -68179,8 +65988,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL182W and YPL231W" - eccodes: "2.3.1.86" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -68196,15 +66004,13 @@ - s_0372: -1 - s_0460: 1 - s_0465: -1 - - s_0799: -1 - s_1845: 1 - s_2770: 1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER061C and YKL192C" - eccodes: "2.3.1.41" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "3OAS40_m" - kegg.pathway: @@ -68222,7 +66028,6 @@ - metabolites: !!omap - s_0460: 1 - s_0465: -1 - - s_0799: -1 - s_1845: 1 - s_2771: -1 - s_2772: 1 @@ -68230,8 +66035,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER061C and YKL192C" - eccodes: "2.3.1.41" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -68248,7 +66052,6 @@ - metabolites: !!omap - s_0460: 1 - s_0465: -1 - - s_0799: -1 - s_1845: 1 - s_2773: -1 - s_2774: 1 @@ -68256,8 +66059,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER061C and YKL192C" - eccodes: "2.3.1.41" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -68281,8 +66083,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL055C" - eccodes: "1.1.1.100" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "3OAR40_m" - kegg.pathway: @@ -68308,8 +66109,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL055C" - eccodes: "1.1.1.100" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "3OAR60_m" - kegg.pathway: @@ -68335,8 +66135,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL055C" - eccodes: "1.1.1.100" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -68361,8 +66160,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR067W" - eccodes: "4.2.1.-" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - pubmed: "15387819" - sbo: "SBO:0000176" @@ -68379,8 +66177,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR067W" - eccodes: "4.2.1.-" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "3HAD61_m" - pubmed: "15387819" @@ -68398,8 +66195,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR067W" - eccodes: "4.2.1.-" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - metanetx.reaction: "MNXR137214" - pubmed: "15387819" @@ -68420,8 +66216,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR026C" - eccodes: "1.3.1.104" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68443,8 +66238,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR026C" - eccodes: "1.3.1.104" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68466,8 +66260,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR026C" - eccodes: "1.3.1.104" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68490,8 +66283,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL196C" - eccodes: "2.3.1.199" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68517,8 +66309,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL196C" - eccodes: "2.3.1.199" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68544,8 +66335,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR034W" - eccodes: "2.3.1.199" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68572,8 +66362,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR034W or YLR372W" - eccodes: "2.3.1.199" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68599,8 +66388,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR034W or YLR372W" - eccodes: "2.3.1.199" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68625,8 +66413,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR034W or YLR372W" - eccodes: "2.3.1.199" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68651,8 +66438,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR372W" - eccodes: "2.3.1.199" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68677,8 +66463,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR159W" - eccodes: "1.1.1.330" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68702,8 +66487,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR159W" - eccodes: "1.1.1.330" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68727,8 +66511,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR159W" - eccodes: "1.1.1.330" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68754,8 +66537,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR159W" - eccodes: "1.1.1.330" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68780,8 +66562,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR159W" - eccodes: "1.1.1.330" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68806,8 +66587,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR159W" - eccodes: "1.1.1.330" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68833,8 +66613,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR159W" - eccodes: "1.1.1.330" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68856,8 +66635,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL097W" - eccodes: "4.2.1.134" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68881,8 +66659,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL097W" - eccodes: "4.2.1.134" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68904,8 +66681,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL097W" - eccodes: "4.2.1.134" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68929,8 +66705,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL097W" - eccodes: "4.2.1.134" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68952,8 +66727,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL097W" - eccodes: "4.2.1.134" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -68975,8 +66749,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL097W" - eccodes: "4.2.1.134" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -69000,8 +66773,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL097W" - eccodes: "4.2.1.134" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -69025,8 +66797,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL015C" - eccodes: "1.3.1.93" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -69052,8 +66823,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL015C" - eccodes: "1.3.1.93" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -69077,8 +66847,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL015C" - eccodes: "1.3.1.93" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -69104,8 +66873,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL015C" - eccodes: "1.3.1.93" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -69129,8 +66897,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL015C" - eccodes: "1.3.1.93" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -69154,8 +66921,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL015C" - eccodes: "1.3.1.93" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -69179,8 +66945,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL015C" - eccodes: "1.3.1.93" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -69207,8 +66972,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL055W" - eccodes: "1.14.19.1" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce01040" @@ -69232,8 +66996,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL055W" - eccodes: "1.14.19.1" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce01040" @@ -69250,8 +67013,7 @@ - s_1250: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "OCTAt" - metanetx.reaction: "MNXR99126" @@ -69266,8 +67028,7 @@ - s_0597: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "DCATDc" - metanetx.reaction: "MNXR135772" @@ -69283,8 +67044,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "r2444" - metanetx.reaction: "MNXR135773" @@ -69298,8 +67058,7 @@ - s_2822: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_but_e" - sbo: "SBO:0000627" @@ -69311,8 +67070,7 @@ - s_2824: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_hxa_e" - sbo: "SBO:0000627" @@ -69324,8 +67082,7 @@ - s_2826: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ocdcea_e" - sbo: "SBO:0000627" @@ -69339,8 +67096,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNL065W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "BUTt" - sbo: "SBO:0000655" @@ -69355,8 +67111,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNL065W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "HXAt3" - metanetx.reaction: "MNXR100750" @@ -69372,8 +67127,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "OCDCEAt" - metanetx.reaction: "MNXR99110" @@ -69387,8 +67141,7 @@ - s_1163: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ttdca_e" - sbo: "SBO:0000627" @@ -69407,8 +67160,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69434,8 +67186,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR246W or YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69461,8 +67212,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR246W or YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69489,8 +67239,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR246W or YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69516,8 +67265,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR246W or YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69543,8 +67291,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR246W or YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69570,8 +67317,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69597,8 +67343,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR246W or YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69624,8 +67369,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR246W or YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69652,8 +67396,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR246W or YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69679,8 +67422,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR246W or YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69706,8 +67448,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR246W or YOR317W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69733,8 +67474,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER015W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "FACOAL161p" - kegg.pathway: @@ -69761,8 +67501,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER015W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69788,8 +67527,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER015W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69815,8 +67553,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL009W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69841,8 +67578,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL009W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69867,8 +67603,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL009W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69894,8 +67629,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL009W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -69920,8 +67654,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -69940,8 +67673,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - metanetx.reaction: "MNXR126665" - pubmed: "22345606" @@ -69961,8 +67693,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - metanetx.reaction: "MNXR128076" - pubmed: "22345606" @@ -69982,8 +67713,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -70002,8 +67732,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - metanetx.reaction: "MNXR126665" - pubmed: "22345606" @@ -70023,8 +67752,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR041W" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - metanetx.reaction: "MNXR128076" - pubmed: "22345606" @@ -70045,8 +67773,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - kegg.pathway: - "sce02010" @@ -70069,8 +67796,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - kegg.pathway: - "sce02010" @@ -70093,8 +67819,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "FA160COAabcp_1" - kegg.pathway: @@ -70119,8 +67844,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - kegg.pathway: - "sce02010" @@ -70143,8 +67867,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "STCOATxc" - kegg.pathway: @@ -70169,8 +67892,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - kegg.pathway: - "sce02010" @@ -70193,8 +67915,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - kegg.pathway: - "sce02010" @@ -70217,8 +67938,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "DOCOSCOAtxc" - kegg.pathway: @@ -70242,8 +67962,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "LGNCCOAtcx_1" - kegg.pathway: @@ -70267,8 +67986,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - kegg.pathway: - "sce02010" @@ -70285,8 +68003,7 @@ - s_2882: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -1.16 @@ -70299,8 +68016,7 @@ - s_2883: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - bigg.reaction: "HXAt2" - metanetx.reaction: "MNXR100750" @@ -70316,8 +68032,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKL188C and YPL147W" - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - metanetx.reaction: "MNXR99110" - sbo: "SBO:0000655" @@ -70328,7 +68043,7 @@ - name: "peroxisomal acyl-CoA thioesterase (4:0)" - metabolites: !!omap - s_0534: 1 - - s_0801: 5 + - s_0801: 1 - s_0809: -1 - s_2882: 1 - s_2884: -1 @@ -70336,8 +68051,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR019C" - eccodes: "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -70361,8 +68075,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR019C" - eccodes: "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - bigg.reaction: "HXCOAx" - kegg.pathway: @@ -70388,8 +68101,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR019C" - eccodes: "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -70413,8 +68125,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR019C" - eccodes: "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - kegg.pathway: - "sce00062" @@ -70433,13 +68144,12 @@ - s_0840: 1 - s_1279: -1 - s_2884: -1 - - s_2886: 1 + - s_4334: 1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HMR_3102" - kegg.pathway: @@ -70466,8 +68176,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HMR_3098" - kegg.pathway: @@ -70494,8 +68203,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -70519,8 +68227,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -70544,8 +68251,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -70569,8 +68275,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HMR_3062" - kegg.pathway: @@ -70598,8 +68303,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -70624,8 +68328,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -70649,8 +68352,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -70674,8 +68376,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -70699,8 +68400,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -70724,8 +68424,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL205W" - eccodes: "1.3.3.6" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -70750,8 +68449,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ECOAH4p" - kegg.reaction: "R04744" @@ -70773,8 +68471,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ECOAH5p" - kegg.reaction: "R04170" @@ -70796,8 +68493,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ECOAH6p" - kegg.reaction: "R04740" @@ -70819,8 +68515,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ECOAH7p" - kegg.reaction: "R04738" @@ -70842,8 +68537,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HMR_3075" - kegg.reaction: "R07760" @@ -70865,8 +68559,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -70876,18 +68569,16 @@ - id: "r_2254" - name: "2-enoyl-CoA hydratase (3-hydroxybutanoyl-CoA)" - metabolites: !!omap - - s_0801: 4 - s_0809: -1 - - s_2886: -1 - s_2902: 1 + - s_4334: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKR009C" - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -70907,8 +68598,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -70928,8 +68618,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - metanetx.reaction: "MNXR118594" - pubmed: "12697341" @@ -70950,8 +68639,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -70970,8 +68658,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -70990,8 +68677,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - metanetx.reaction: "MNXR118009" - pubmed: "12697341" @@ -71012,8 +68698,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71032,8 +68717,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71052,8 +68736,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71073,8 +68756,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71094,8 +68776,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71114,8 +68795,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71136,8 +68816,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HACD4p" - kegg.reaction: "R04743" @@ -71161,8 +68840,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HACD5p" - kegg.reaction: "R04741" @@ -71186,8 +68864,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HACD7p" - kegg.reaction: "R04737" @@ -71211,8 +68888,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HMR_3076" - metanetx.reaction: "MNXR126787" @@ -71235,8 +68911,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71257,8 +68932,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71279,8 +68953,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71301,8 +68974,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71323,8 +68995,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71345,8 +69016,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71367,8 +69037,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71389,8 +69058,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71411,8 +69079,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71433,8 +69100,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71455,8 +69121,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71477,8 +69142,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71499,8 +69163,7 @@ - eccodes: - "1.1.1.n12" - "4.2.1.119" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71517,8 +69180,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACACT1x" - kegg.pathway: @@ -71541,14 +69203,14 @@ - metabolites: !!omap - s_0378: 1 - s_0534: -1 + - s_0801: 4 - s_2884: 1 - s_2915: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACACT2" - kegg.pathway: @@ -71575,8 +69237,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "ACACT3" - kegg.pathway: @@ -71603,8 +69264,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HMR_3073" - kegg.pathway: @@ -71631,8 +69291,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HMR_3069" - kegg.pathway: @@ -71659,8 +69318,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "HMR_3065" - kegg.pathway: @@ -71687,8 +69345,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71714,8 +69371,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71741,8 +69397,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71768,8 +69423,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71795,8 +69449,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71822,8 +69475,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL160C" - eccodes: "2.3.1.16" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71848,8 +69500,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR284C" - eccodes: "5.3.3.8" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71869,8 +69520,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR284C" - eccodes: "5.3.3.8" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71890,8 +69540,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR284C" - eccodes: "5.3.3.8" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - bigg.reaction: "FAOXC121x" - kegg.pathway: @@ -71913,8 +69562,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR284C" - eccodes: "5.3.3.8" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71934,8 +69582,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR284C" - eccodes: "5.3.3.8" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71955,8 +69602,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR284C" - eccodes: "5.3.3.8" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - kegg.pathway: - "sce00071" @@ -71976,8 +69622,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR180C" - eccodes: "5.3.3.-" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -71993,8 +69638,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR180C" - eccodes: "5.3.3.-" - - subsystem: - - "Fatty acid degradation" + - subsystem: "Fatty acid degradation" - annotation: !!omap - pubmed: "12697341" - sbo: "SBO:0000176" @@ -72013,8 +69657,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL202W" - eccodes: "1.3.1.34" - - subsystem: - - "Ascospore biosynthesis" + - subsystem: "Ascospore biosynthesis" - annotation: !!omap - kegg.pathway: "sce04146" - pubmed: "12697341" @@ -72034,8 +69677,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL202W" - eccodes: "1.3.1.34" - - subsystem: - - "Ascospore biosynthesis" + - subsystem: "Ascospore biosynthesis" - annotation: !!omap - kegg.pathway: "sce04146" - pubmed: "12697341" @@ -72053,8 +69695,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR304C" - eccodes: "4.2.1.3" - - subsystem: - - "Citrate cycle (TCA cycle)" + - subsystem: "Citrate cycle (TCA cycle)" - annotation: !!omap - bigg.reaction: "ACONTb" - kegg.pathway: @@ -72086,8 +69727,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72113,8 +69753,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72140,8 +69779,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72167,8 +69805,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72194,8 +69831,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72221,8 +69857,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72248,8 +69883,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72275,8 +69909,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72302,8 +69935,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72329,8 +69961,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72356,8 +69987,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72383,8 +70013,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72410,8 +70039,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72437,8 +70065,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72464,8 +70091,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72491,8 +70117,7 @@ - eccodes: - "2.3.1.15" - "2.3.1.42" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72516,8 +70141,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL124W" - eccodes: "1.1.1.101" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -72537,8 +70161,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL124W" - eccodes: "1.1.1.101" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -72558,8 +70181,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL124W" - eccodes: "1.1.1.101" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -72579,8 +70201,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL124W" - eccodes: "1.1.1.101" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -72600,8 +70221,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL124W" - eccodes: "1.1.1.101" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -72621,8 +70241,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL124W" - eccodes: "1.1.1.101" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -72642,8 +70261,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL124W" - eccodes: "1.1.1.101" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -72663,8 +70281,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL124W" - eccodes: "1.1.1.101" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -72685,8 +70302,7 @@ - eccodes: - "2.3.1.23" - "2.3.1.51" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72706,12 +70322,11 @@ - s_2955: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "YDL052C or YOR175C" + - gene_reaction_rule: "YOR175C or YPR139C" - eccodes: - "2.3.1.23" - "2.3.1.51" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72735,8 +70350,7 @@ - eccodes: - "2.3.1.23" - "2.3.1.51" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72756,12 +70370,11 @@ - s_2957: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "YDL052C or YOR175C" + - gene_reaction_rule: "YOR175C or YPR139C" - eccodes: - "2.3.1.23" - "2.3.1.51" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72785,8 +70398,7 @@ - eccodes: - "2.3.1.23" - "2.3.1.51" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72806,12 +70418,11 @@ - s_2959: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "YDL052C or YOR175C" + - gene_reaction_rule: "YOR175C or YPR139C" - eccodes: - "2.3.1.23" - "2.3.1.51" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72835,8 +70446,7 @@ - eccodes: - "2.3.1.23" - "2.3.1.51" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72860,8 +70470,7 @@ - eccodes: - "2.3.1.23" - "2.3.1.51" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -72885,8 +70494,7 @@ - eccodes: - "2.3.1.51" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -72911,8 +70519,7 @@ - eccodes: - "2.3.1.51" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -72937,8 +70544,7 @@ - eccodes: - "2.3.1.51" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -72963,8 +70569,7 @@ - eccodes: - "2.3.1.51" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -72988,8 +70593,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR165C" - eccodes: "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73013,8 +70617,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR165C" - eccodes: "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73038,8 +70641,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR165C" - eccodes: "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73063,8 +70665,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR165C" - eccodes: "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73088,8 +70689,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR165C" - eccodes: "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73113,8 +70713,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR165C" - eccodes: "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73138,8 +70737,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR165C" - eccodes: "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73163,8 +70761,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR165C" - eccodes: "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73190,8 +70787,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73217,8 +70813,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73244,8 +70839,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73271,8 +70865,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73298,8 +70891,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73325,8 +70917,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73352,8 +70943,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73379,8 +70969,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -73406,8 +70995,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -73429,8 +71017,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -73452,8 +71039,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -73475,8 +71061,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -73498,8 +71083,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -73521,8 +71105,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -73544,8 +71127,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -73567,8 +71149,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -73590,8 +71171,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73615,8 +71195,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73640,8 +71219,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73665,8 +71243,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73690,8 +71267,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73715,8 +71291,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73740,8 +71315,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73765,8 +71339,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73790,8 +71363,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73815,8 +71387,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73840,8 +71411,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73865,8 +71435,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73890,8 +71459,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73915,8 +71483,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73940,8 +71507,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73965,8 +71531,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -73990,8 +71555,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74015,8 +71579,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74040,8 +71603,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74065,8 +71627,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74090,8 +71651,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74115,8 +71675,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74140,8 +71699,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74165,8 +71723,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74190,8 +71747,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74215,8 +71771,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74240,8 +71795,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74265,8 +71819,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74290,8 +71843,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74315,8 +71867,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74340,8 +71891,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74365,8 +71915,7 @@ - "2.3.1.20" - "2.3.1.22" - "2.3.1.26" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -74389,8 +71938,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74411,8 +71959,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74433,8 +71980,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74455,8 +72001,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74477,8 +72022,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74499,8 +72043,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74521,8 +72064,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74543,8 +72085,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74565,8 +72106,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74587,8 +72127,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74609,8 +72148,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74631,8 +72169,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74653,8 +72190,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74675,8 +72211,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74697,8 +72232,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74719,8 +72253,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74741,8 +72274,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74763,8 +72295,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74785,8 +72316,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74807,8 +72337,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74829,8 +72358,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74851,8 +72379,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74873,8 +72400,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74895,8 +72421,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74917,8 +72442,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74939,8 +72463,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74961,8 +72484,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -74983,8 +72505,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -75005,8 +72526,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -75027,8 +72547,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -75049,8 +72568,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -75071,8 +72589,7 @@ - eccodes: - "2.3.1.20" - "2.3.1.22" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -75092,8 +72609,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR029C" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75116,8 +72632,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR029C" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75140,8 +72655,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR029C" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75164,8 +72678,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR029C" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75188,8 +72701,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR029C" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75212,8 +72724,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR029C" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75236,8 +72747,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR029C" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75260,8 +72770,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR029C" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75284,8 +72793,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR029C" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75306,10 +72814,9 @@ - s_3098: 1 - lower_bound: -1000 - upper_bound: 1000 - - gene_reaction_rule: "YBR029C" + - gene_reaction_rule: "YGR046W" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75330,10 +72837,9 @@ - s_3100: 1 - lower_bound: -1000 - upper_bound: 1000 - - gene_reaction_rule: "YBR029C" + - gene_reaction_rule: "YGR046W" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75354,10 +72860,9 @@ - s_3102: 1 - lower_bound: -1000 - upper_bound: 1000 - - gene_reaction_rule: "YBR029C" + - gene_reaction_rule: "YGR046W" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75378,10 +72883,9 @@ - s_3104: 1 - lower_bound: -1000 - upper_bound: 1000 - - gene_reaction_rule: "YBR029C" + - gene_reaction_rule: "YGR046W" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75402,10 +72906,9 @@ - s_3106: 1 - lower_bound: -1000 - upper_bound: 1000 - - gene_reaction_rule: "YBR029C" + - gene_reaction_rule: "YGR046W" - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75428,8 +72931,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER026C" - eccodes: "2.7.8.8" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00260" @@ -75453,8 +72955,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER026C" - eccodes: "2.7.8.8" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00260" @@ -75478,8 +72979,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER026C" - eccodes: "2.7.8.8" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00260" @@ -75503,8 +73003,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER026C" - eccodes: "2.7.8.8" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00260" @@ -75528,8 +73027,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER026C" - eccodes: "2.7.8.8" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00260" @@ -75553,8 +73051,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER026C" - eccodes: "2.7.8.8" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00260" @@ -75578,8 +73075,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER026C" - eccodes: "2.7.8.8" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00260" @@ -75603,8 +73099,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER026C" - eccodes: "2.7.8.8" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00260" @@ -75628,8 +73123,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR113W" - eccodes: "2.7.8.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -75653,8 +73147,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR113W" - eccodes: "2.7.8.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -75678,8 +73171,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR113W" - eccodes: "2.7.8.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -75703,8 +73195,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR113W" - eccodes: "2.7.8.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -75728,8 +73219,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR113W" - eccodes: "2.7.8.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -75753,8 +73243,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR113W" - eccodes: "2.7.8.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -75778,8 +73267,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR113W" - eccodes: "2.7.8.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -75803,8 +73291,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR113W" - eccodes: "2.7.8.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -75827,8 +73314,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR042C" - eccodes: "2.3.-.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -75846,8 +73332,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR042C" - eccodes: "2.3.-.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -75864,8 +73349,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL169C" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75886,8 +73370,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL169C" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75908,8 +73391,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL169C" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75930,8 +73412,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL169C" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75952,8 +73433,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL169C" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75974,8 +73454,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL169C" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -75996,8 +73475,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL169C" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76018,8 +73496,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL169C" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76040,8 +73517,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76062,8 +73538,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76084,8 +73559,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76106,8 +73580,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76128,8 +73601,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76150,8 +73622,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76172,8 +73643,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76194,8 +73664,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76216,8 +73685,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76238,8 +73706,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76260,8 +73727,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76282,8 +73748,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76304,8 +73769,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76326,8 +73790,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76348,8 +73811,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76370,8 +73832,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR170W" - eccodes: "4.1.1.65" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76397,8 +73858,7 @@ - "2.1.1.17" - "2.1.1.71" - references: "10.1016/0005-2760(90)90145-N" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76423,8 +73883,7 @@ - "2.1.1.17" - "2.1.1.71" - references: "10.1016/0005-2760(90)90145-N" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76449,8 +73908,7 @@ - "2.1.1.17" - "2.1.1.71" - references: "10.1016/0005-2760(90)90145-N" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76475,8 +73933,7 @@ - "2.1.1.17" - "2.1.1.71" - references: "10.1016/0005-2760(90)90145-N" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76501,8 +73958,7 @@ - "2.1.1.17" - "2.1.1.71" - references: "10.1016/0005-2760(90)90145-N" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76527,8 +73983,7 @@ - "2.1.1.17" - "2.1.1.71" - references: "10.1016/0005-2760(90)90145-N" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76553,8 +74008,7 @@ - "2.1.1.17" - "2.1.1.71" - references: "10.1016/0005-2760(90)90145-N" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76579,8 +74033,7 @@ - "2.1.1.17" - "2.1.1.71" - references: "10.1016/0005-2760(90)90145-N" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76604,8 +74057,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76629,8 +74081,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76654,8 +74105,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76679,8 +74129,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76704,8 +74153,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76729,8 +74177,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76754,8 +74201,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76779,8 +74225,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76804,8 +74249,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76829,8 +74273,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76854,8 +74297,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76879,8 +74321,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76904,8 +74345,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76929,8 +74369,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76954,8 +74393,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -76979,8 +74417,7 @@ - eccodes: - "2.1.1.17" - "2.1.1.71" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -77002,8 +74439,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR311C" - eccodes: "2.7.1.174" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -77026,8 +74462,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR311C" - eccodes: "2.7.1.174" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -77050,8 +74485,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR311C" - eccodes: "2.7.1.174" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -77074,8 +74508,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR311C" - eccodes: "2.7.1.174" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -77098,8 +74531,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR311C" - eccodes: "2.7.1.174" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -77122,8 +74554,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR311C" - eccodes: "2.7.1.174" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -77146,8 +74577,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR311C" - eccodes: "2.7.1.174" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -77170,8 +74600,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR311C" - eccodes: "2.7.1.174" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -77196,8 +74625,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77222,8 +74650,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77248,8 +74675,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77274,8 +74700,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77300,8 +74725,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77326,8 +74750,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77352,8 +74775,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77378,8 +74800,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77404,8 +74825,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77430,8 +74850,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77456,8 +74875,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77482,8 +74900,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77508,8 +74925,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77534,8 +74950,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77560,8 +74975,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77586,8 +75000,7 @@ - eccodes: - "2.7.8.1" - "2.7.8.2" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00440" @@ -77609,8 +75022,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL004W" - eccodes: "2.7.8.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77630,8 +75042,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL004W" - eccodes: "2.7.8.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77651,8 +75062,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL004W" - eccodes: "2.7.8.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77672,8 +75082,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL004W" - eccodes: "2.7.8.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77693,8 +75102,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL004W" - eccodes: "2.7.8.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77714,8 +75122,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCL004W" - eccodes: "2.7.8.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77736,8 +75143,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR100C" - eccodes: "3.1.3.27" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77758,8 +75164,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR100C" - eccodes: "3.1.3.27" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77780,8 +75185,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR100C" - eccodes: "3.1.3.27" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77802,8 +75206,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR100C" - eccodes: "3.1.3.27" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77824,8 +75227,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR100C" - eccodes: "3.1.3.27" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77846,8 +75248,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR100C" - eccodes: "3.1.3.27" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77868,8 +75269,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77890,8 +75290,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77912,8 +75311,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77934,8 +75332,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77956,8 +75353,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -77978,8 +75374,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78000,8 +75395,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78022,8 +75416,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78044,8 +75437,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78066,8 +75458,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78088,8 +75479,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78110,8 +75500,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78132,8 +75521,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78154,8 +75542,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78176,8 +75563,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78198,8 +75584,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78220,8 +75605,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78242,8 +75626,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78264,8 +75647,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78286,8 +75668,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78308,8 +75689,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78330,8 +75710,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78352,8 +75731,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78374,8 +75752,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78396,8 +75773,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78418,8 +75794,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78440,8 +75815,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78462,8 +75836,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78484,8 +75857,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78506,8 +75878,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78528,8 +75899,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78550,8 +75920,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78572,8 +75941,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78594,8 +75962,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78616,8 +75983,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78638,8 +76004,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL142C" - eccodes: "2.7.8.41" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78660,8 +76025,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78681,8 +76045,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78702,8 +76065,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78723,8 +76085,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78744,8 +76105,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78765,8 +76125,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78786,8 +76145,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78807,8 +76165,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78828,8 +76185,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78849,8 +76205,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78870,8 +76225,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78891,8 +76245,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78912,8 +76265,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78933,8 +76285,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78954,8 +76305,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78975,8 +76325,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -78996,8 +76345,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79017,8 +76365,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79038,8 +76385,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79059,8 +76405,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79080,8 +76425,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79101,8 +76445,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79122,8 +76465,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79143,8 +76485,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79164,8 +76505,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79185,8 +76525,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79206,8 +76545,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79227,8 +76565,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79248,8 +76585,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79269,8 +76605,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79290,8 +76625,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79311,8 +76645,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79332,8 +76665,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79353,8 +76685,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79374,8 +76705,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79395,8 +76725,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR110W" - eccodes: "3.5.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79415,8 +76744,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79435,8 +76763,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79455,8 +76782,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79475,8 +76801,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79495,8 +76820,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79515,8 +76839,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79535,8 +76858,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79555,8 +76877,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79575,8 +76896,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79595,8 +76915,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79615,8 +76934,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79635,8 +76953,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79655,8 +76972,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79675,8 +76991,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79695,8 +77010,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79715,8 +77029,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79735,8 +77048,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79755,8 +77067,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79775,8 +77086,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79795,8 +77105,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79815,8 +77124,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79835,8 +77143,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79855,8 +77162,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79875,8 +77181,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79895,8 +77200,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79915,8 +77219,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79935,8 +77238,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79955,8 +77257,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79975,8 +77276,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -79995,8 +77295,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80015,8 +77314,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80035,8 +77333,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80055,8 +77352,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80075,8 +77371,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80095,8 +77390,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80115,8 +77409,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80135,8 +77428,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80155,8 +77447,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80175,8 +77466,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80195,8 +77485,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80215,8 +77504,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80235,8 +77523,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80255,8 +77542,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80275,8 +77561,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80295,8 +77580,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80315,8 +77599,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80335,8 +77618,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80355,8 +77637,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80375,8 +77656,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80395,8 +77675,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80415,8 +77694,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80435,8 +77713,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80455,8 +77732,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80475,8 +77751,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80495,8 +77770,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80515,8 +77789,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80535,8 +77808,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80555,8 +77827,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80575,8 +77846,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80595,8 +77865,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80615,8 +77884,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80635,8 +77903,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80655,8 +77922,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80675,8 +77941,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80695,8 +77960,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80715,8 +77979,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80735,8 +77998,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80755,8 +78017,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80775,8 +78036,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80795,8 +78055,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80815,8 +78074,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80835,8 +78093,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80855,8 +78112,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80875,8 +78131,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80895,8 +78150,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80915,8 +78169,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80935,8 +78188,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80955,8 +78207,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80975,8 +78226,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -80995,8 +78245,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81015,8 +78264,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81035,8 +78283,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81055,8 +78302,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81075,8 +78321,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81095,8 +78340,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81115,8 +78359,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81135,8 +78378,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81155,8 +78397,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81175,8 +78416,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81195,8 +78435,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81215,8 +78454,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81235,8 +78473,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81255,8 +78492,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81275,8 +78511,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81295,8 +78530,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81315,8 +78549,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81335,8 +78568,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81355,8 +78587,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81375,8 +78606,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81395,8 +78625,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81415,8 +78644,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81435,8 +78663,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81455,8 +78682,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81475,8 +78701,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81495,8 +78720,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81515,8 +78739,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81535,8 +78758,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81555,8 +78777,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81575,8 +78796,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81595,8 +78815,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81615,8 +78834,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81635,8 +78853,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81655,8 +78872,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81675,8 +78891,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81695,8 +78910,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81715,8 +78929,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81735,8 +78948,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81755,8 +78967,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81775,8 +78986,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81795,8 +79005,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81815,8 +79024,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81835,8 +79043,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81855,8 +79062,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81875,8 +79081,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81895,8 +79100,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81915,8 +79119,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81935,8 +79138,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81955,8 +79157,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81975,8 +79176,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -81995,8 +79195,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82015,8 +79214,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82035,8 +79233,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82055,8 +79252,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82075,8 +79271,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82095,8 +79290,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82115,8 +79309,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82135,8 +79328,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82155,8 +79347,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82175,8 +79366,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82195,8 +79385,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82215,8 +79404,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82235,8 +79423,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82255,8 +79442,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82275,8 +79461,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82295,8 +79480,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82315,8 +79499,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82335,8 +79518,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82355,8 +79537,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82375,8 +79556,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82395,8 +79575,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82415,8 +79594,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82435,8 +79613,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82455,8 +79632,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82475,8 +79651,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82495,8 +79670,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82515,8 +79689,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82535,8 +79708,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82555,8 +79727,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82575,8 +79746,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82595,8 +79765,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82615,8 +79784,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82635,8 +79803,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82655,8 +79822,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82675,8 +79841,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82695,8 +79860,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82715,8 +79879,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82735,8 +79898,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82755,8 +79917,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82775,8 +79936,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82795,8 +79955,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82815,8 +79974,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82835,8 +79993,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82855,8 +80012,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82875,8 +80031,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82895,8 +80050,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82915,8 +80069,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82935,8 +80088,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82955,8 +80107,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82975,8 +80126,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -82995,8 +80145,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83015,8 +80164,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83035,8 +80183,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83055,8 +80202,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83075,8 +80221,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83095,8 +80240,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83115,8 +80259,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83135,8 +80278,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83155,8 +80297,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83175,8 +80316,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83195,8 +80335,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83215,8 +80354,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83235,8 +80373,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR140W" - eccodes: "2.3.1.23" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -83253,8 +80390,7 @@ - s_3321: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -3.61 @@ -83269,8 +80405,7 @@ - s_3322: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -3.61 @@ -83285,8 +80420,7 @@ - s_3321: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -3.61 @@ -83301,8 +80435,7 @@ - s_3322: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -3.61 @@ -83317,8 +80450,7 @@ - s_3321: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -3.61 @@ -83333,8 +80465,7 @@ - s_3322: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -3.61 @@ -83349,8 +80480,7 @@ - s_3321: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -3.61 @@ -83365,8 +80495,7 @@ - s_3322: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -3.61 @@ -83384,8 +80513,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W or YLR305C" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83409,8 +80537,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W or YLR305C" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83434,8 +80561,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W or YLR305C" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83459,8 +80585,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W or YLR305C" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83484,8 +80609,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W or YLR305C" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83509,8 +80633,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W or YLR305C" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83534,8 +80657,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W or YLR305C" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83559,8 +80681,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W or YLR305C" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83584,8 +80705,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83608,8 +80728,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83632,8 +80751,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83656,8 +80774,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83680,8 +80797,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83704,8 +80820,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83728,8 +80843,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83752,8 +80866,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL100W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83776,8 +80889,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR373W and YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83800,8 +80912,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR373W and YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83824,8 +80935,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR373W and YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83848,8 +80958,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR373W and YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83872,8 +80981,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR373W and YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83896,8 +81004,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR373W and YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83920,8 +81027,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR373W and YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83944,8 +81050,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR373W and YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83968,8 +81073,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -83992,8 +81096,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84016,8 +81119,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84040,8 +81142,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84064,8 +81165,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84088,8 +81188,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84112,8 +81211,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84136,8 +81234,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL267W" - eccodes: "2.7.1.67" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84162,8 +81259,7 @@ - eccodes: - "2.7.1.137" - "2.7.11.1" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84191,8 +81287,7 @@ - eccodes: - "2.7.1.137" - "2.7.11.1" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84220,8 +81315,7 @@ - eccodes: - "2.7.1.137" - "2.7.11.1" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84249,8 +81343,7 @@ - eccodes: - "2.7.1.137" - "2.7.11.1" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84278,8 +81371,7 @@ - eccodes: - "2.7.1.137" - "2.7.11.1" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84307,8 +81399,7 @@ - eccodes: - "2.7.1.137" - "2.7.11.1" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84336,8 +81427,7 @@ - eccodes: - "2.7.1.137" - "2.7.11.1" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84365,8 +81455,7 @@ - eccodes: - "2.7.1.137" - "2.7.11.1" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84392,8 +81481,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84419,8 +81507,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84446,8 +81533,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84473,8 +81559,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84500,8 +81585,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84527,8 +81611,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84554,8 +81637,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84581,8 +81663,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84608,8 +81689,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84635,8 +81715,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84662,8 +81741,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84689,8 +81767,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84716,8 +81793,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84743,8 +81819,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84770,8 +81845,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84797,8 +81871,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR208W" - eccodes: "2.7.1.68" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84824,8 +81897,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W" - eccodes: "2.7.1.150" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84849,8 +81921,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W" - eccodes: "2.7.1.150" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84874,8 +81945,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W" - eccodes: "2.7.1.150" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84899,8 +81969,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W" - eccodes: "2.7.1.150" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84924,8 +81993,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W" - eccodes: "2.7.1.150" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84949,8 +82017,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W" - eccodes: "2.7.1.150" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84974,8 +82041,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W" - eccodes: "2.7.1.150" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -84999,8 +82065,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W" - eccodes: "2.7.1.150" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -85023,8 +82088,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85043,8 +82107,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85063,8 +82126,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85083,8 +82145,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85103,8 +82164,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85123,8 +82183,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85143,8 +82202,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85163,8 +82221,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85183,8 +82240,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85203,8 +82259,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85223,8 +82278,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85243,8 +82297,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85263,8 +82316,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85283,8 +82335,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85303,8 +82354,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85323,8 +82373,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85343,8 +82392,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85363,8 +82411,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85383,8 +82430,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85403,8 +82449,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85423,8 +82468,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85443,8 +82487,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85463,8 +82506,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85483,8 +82525,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85503,8 +82544,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85523,8 +82563,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85543,8 +82582,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85563,8 +82601,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85583,8 +82620,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85603,8 +82639,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85623,8 +82658,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85643,8 +82677,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85663,8 +82696,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85683,8 +82715,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85703,8 +82734,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85723,8 +82753,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85743,8 +82772,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85763,8 +82791,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85783,8 +82810,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85803,8 +82829,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85823,8 +82848,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85843,8 +82867,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85863,8 +82886,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85883,8 +82905,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85903,8 +82924,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85923,8 +82943,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85943,8 +82962,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85963,8 +82981,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -85983,8 +83000,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86003,8 +83019,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86023,8 +83038,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86043,8 +83057,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86063,8 +83076,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86083,8 +83095,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86103,8 +83114,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86123,8 +83133,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86143,8 +83152,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86163,8 +83171,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86183,8 +83190,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86203,8 +83209,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86223,8 +83228,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86243,8 +83247,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86263,8 +83266,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86283,8 +83285,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86303,8 +83304,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86323,8 +83323,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86343,8 +83342,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86363,8 +83361,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86383,8 +83380,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86403,8 +83399,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86423,8 +83418,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86443,8 +83437,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86463,8 +83456,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86483,8 +83475,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86503,8 +83494,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86523,8 +83513,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86543,8 +83532,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86563,8 +83551,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86583,8 +83570,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86603,8 +83589,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86623,8 +83608,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86643,8 +83627,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86663,8 +83646,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86683,8 +83665,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86703,8 +83684,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86723,8 +83703,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86743,8 +83722,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86763,8 +83741,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86783,8 +83760,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86803,8 +83779,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86823,8 +83798,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86843,8 +83817,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86863,8 +83836,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86883,8 +83855,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86903,8 +83874,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86923,8 +83893,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86943,8 +83912,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86963,8 +83931,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -86983,8 +83950,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87003,8 +83969,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87023,8 +83988,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87043,8 +84007,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87063,8 +84026,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87083,8 +84045,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87103,8 +84064,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87123,8 +84083,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87143,8 +84102,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87163,8 +84121,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87183,8 +84140,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87203,8 +84159,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87223,8 +84178,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87243,8 +84197,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87263,8 +84216,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87283,8 +84235,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87303,8 +84254,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87323,8 +84273,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87343,8 +84292,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87363,8 +84311,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87383,8 +84330,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87403,8 +84349,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87423,8 +84368,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87443,8 +84387,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87463,8 +84406,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87483,8 +84425,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87503,8 +84444,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87523,8 +84463,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87543,8 +84482,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87563,8 +84501,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR008W" - eccodes: "2.3.1.158" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -87584,8 +84521,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87605,8 +84541,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87626,8 +84561,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87647,8 +84581,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87668,8 +84601,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87689,8 +84621,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87710,8 +84641,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87731,8 +84661,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87752,8 +84681,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87773,8 +84701,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87794,8 +84721,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87815,8 +84741,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML059C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87836,8 +84761,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87857,8 +84781,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87878,8 +84801,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87899,8 +84821,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87920,8 +84841,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87941,8 +84861,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87962,8 +84881,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -87983,8 +84901,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88004,8 +84921,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88025,8 +84941,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88046,8 +84961,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88067,8 +84981,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88088,8 +85001,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88109,8 +85021,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88130,8 +85041,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88151,8 +85061,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88172,8 +85081,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88193,8 +85101,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88214,8 +85121,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88235,8 +85141,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88256,8 +85161,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88277,8 +85181,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88298,8 +85201,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88319,8 +85221,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YMR008C" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88340,8 +85241,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88361,8 +85261,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88382,8 +85281,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88403,8 +85301,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88424,8 +85321,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88445,8 +85341,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88466,8 +85361,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88487,8 +85381,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88508,8 +85401,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88529,8 +85421,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88550,8 +85441,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88571,8 +85461,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR006C or YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88592,8 +85481,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88613,8 +85501,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88634,8 +85521,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88655,8 +85541,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88676,8 +85561,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88697,8 +85581,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88718,8 +85601,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88739,8 +85621,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88760,8 +85641,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88782,8 +85662,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88804,8 +85683,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88826,8 +85704,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL011W" - eccodes: "3.1.1.5" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -88848,8 +85725,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -88873,8 +85749,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -88898,8 +85773,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -88923,8 +85797,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -88948,8 +85821,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -88973,8 +85845,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -88998,8 +85869,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89023,8 +85893,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89048,8 +85917,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89073,8 +85941,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89098,8 +85965,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89123,8 +85989,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89148,8 +86013,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89173,8 +86037,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89198,8 +86061,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89223,8 +86085,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL268W" - eccodes: "3.1.4.11" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89248,8 +86109,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL206C" - eccodes: "3.1.4.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -89270,8 +86130,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL206C" - eccodes: "3.1.4.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -89292,8 +86151,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL206C" - eccodes: "3.1.4.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -89314,8 +86172,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL206C" - eccodes: "3.1.4.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -89336,8 +86193,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL206C" - eccodes: "3.1.4.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -89358,8 +86214,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL206C" - eccodes: "3.1.4.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: "sce00564" - pubmed: "22345606" @@ -89380,8 +86235,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR031C" - eccodes: "3.1.4.4" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -89405,8 +86259,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR031C" - eccodes: "3.1.4.4" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -89430,8 +86283,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR031C" - eccodes: "3.1.4.4" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -89455,8 +86307,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR031C" - eccodes: "3.1.4.4" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -89480,8 +86331,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR031C" - eccodes: "3.1.4.4" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -89505,8 +86355,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR031C" - eccodes: "3.1.4.4" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -89530,8 +86379,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR031C" - eccodes: "3.1.4.4" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -89555,8 +86403,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR031C" - eccodes: "3.1.4.4" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00564" @@ -89582,8 +86429,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89608,8 +86454,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89634,8 +86479,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89660,8 +86504,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89686,8 +86529,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89712,8 +86554,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89738,8 +86579,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89764,8 +86604,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89791,8 +86630,7 @@ - "3.1.3.-" - "3.1.3.36" - "3.1.3.64" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89819,8 +86657,7 @@ - "3.1.3.-" - "3.1.3.36" - "3.1.3.64" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - bigg.reaction: "PIP3P_HDE_HDE_c" - kegg.pathway: @@ -89848,8 +86685,7 @@ - "3.1.3.-" - "3.1.3.36" - "3.1.3.64" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89876,8 +86712,7 @@ - "3.1.3.-" - "3.1.3.36" - "3.1.3.64" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89904,8 +86739,7 @@ - "3.1.3.-" - "3.1.3.36" - "3.1.3.64" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89932,8 +86766,7 @@ - "3.1.3.-" - "3.1.3.36" - "3.1.3.64" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89960,8 +86793,7 @@ - "3.1.3.-" - "3.1.3.36" - "3.1.3.64" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -89988,8 +86820,7 @@ - "3.1.3.-" - "3.1.3.36" - "3.1.3.64" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90013,8 +86844,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90037,8 +86867,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90061,8 +86890,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90085,8 +86913,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90109,8 +86936,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90133,8 +86959,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90157,8 +86982,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90181,8 +87005,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90205,8 +87028,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90229,8 +87051,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90253,8 +87074,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90277,8 +87097,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90301,8 +87120,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90325,8 +87143,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90349,8 +87166,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90373,8 +87189,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90399,8 +87214,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90425,8 +87239,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90451,8 +87264,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90477,8 +87289,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90503,8 +87314,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90529,8 +87339,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90555,8 +87364,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90581,8 +87389,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90607,8 +87414,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90633,8 +87439,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90659,8 +87464,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90685,8 +87489,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90711,8 +87514,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90737,8 +87539,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90763,8 +87564,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90789,8 +87589,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90813,8 +87612,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90837,8 +87635,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90861,8 +87658,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90885,8 +87681,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90909,8 +87704,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90933,8 +87727,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90957,8 +87750,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -90981,8 +87773,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91005,8 +87796,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91029,8 +87819,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91053,8 +87842,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91077,8 +87865,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91101,8 +87888,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91125,8 +87911,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91149,8 +87934,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91173,8 +87957,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL212W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91199,8 +87982,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91225,8 +88007,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91251,8 +88032,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91277,8 +88057,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91303,8 +88082,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91329,8 +88107,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91355,8 +88132,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91381,8 +88157,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91407,8 +88182,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91433,8 +88207,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91459,8 +88232,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91485,8 +88257,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91511,8 +88282,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91537,8 +88307,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91563,8 +88332,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91589,8 +88357,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91615,8 +88382,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91641,8 +88407,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91667,8 +88432,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91693,8 +88457,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91719,8 +88482,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91745,8 +88507,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91771,8 +88532,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91797,8 +88557,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91823,8 +88582,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91849,8 +88607,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91875,8 +88632,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91901,8 +88657,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91927,8 +88682,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91953,8 +88707,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -91979,8 +88732,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -92005,8 +88757,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -92029,8 +88780,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL065C" - eccodes: "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -92053,8 +88803,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL065C" - eccodes: "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -92077,8 +88826,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL065C" - eccodes: "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -92101,8 +88849,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL065C" - eccodes: "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -92125,8 +88872,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL065C" - eccodes: "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -92149,8 +88895,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL065C" - eccodes: "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -92173,8 +88918,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL065C" - eccodes: "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -92197,8 +88941,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL065C" - eccodes: "3.1.3.36" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - kegg.pathway: - "sce00562" @@ -92221,8 +88964,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W and YNL325C and YFR021W and YNL054W and YLR386W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92242,8 +88984,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W and YNL325C and YFR021W and YNL054W and YLR386W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92263,8 +89004,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W and YNL325C and YFR021W and YNL054W and YLR386W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92284,8 +89024,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W and YNL325C and YFR021W and YNL054W and YLR386W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92305,8 +89044,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W and YNL325C and YFR021W and YNL054W and YLR386W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92326,8 +89064,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W and YNL325C and YFR021W and YNL054W and YLR386W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92347,8 +89084,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W and YNL325C and YFR021W and YNL054W and YLR386W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92368,8 +89104,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR019W and YNL325C and YFR021W and YNL054W and YLR386W" - eccodes: "3.1.3.-" - - subsystem: - - "Inositol phosphate metabolism" + - subsystem: "Inositol phosphate metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92391,8 +89126,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92418,8 +89152,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92445,8 +89178,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92472,8 +89204,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92499,8 +89230,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92526,8 +89256,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92553,8 +89282,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92580,8 +89308,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92607,8 +89334,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92630,8 +89356,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92653,8 +89378,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92676,8 +89400,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92699,8 +89422,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92722,8 +89444,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92745,8 +89466,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92768,8 +89488,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92788,8 +89507,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER037W" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92808,8 +89526,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER037W" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92828,8 +89545,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER037W" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92848,8 +89564,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YER037W" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -92871,8 +89586,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92898,8 +89612,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92925,8 +89638,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92952,8 +89664,7 @@ - eccodes: - "3.1.3.4" - "3.1.3.81" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00561" @@ -92979,8 +89690,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -93002,8 +89712,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -93025,8 +89734,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -93048,8 +89756,7 @@ - eccodes: - "3.1.3.-" - "3.1.3.4" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - pubmed: "22345606" - sbo: "SBO:0000176" @@ -93069,8 +89776,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL140W or YLL012W" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - pubmed: @@ -93092,8 +89798,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL140W or YLL012W" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - kegg.pathway: "sce00100" - metanetx.reaction: "MNXR119162" @@ -93116,8 +89821,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL012W" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - pubmed: "16835446" - sbo: "SBO:0000176" @@ -93136,8 +89840,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL012W" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - pubmed: "16835446" - sbo: "SBO:0000176" @@ -93156,8 +89859,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL012W" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - pubmed: "16835446" - sbo: "SBO:0000176" @@ -93176,8 +89878,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL012W" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - pubmed: "16835446" - sbo: "SBO:0000176" @@ -93196,8 +89897,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL012W" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - pubmed: "16835446" - sbo: "SBO:0000176" @@ -93216,8 +89916,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL012W" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - metanetx.reaction: "MNXR119160" - pubmed: "16835446" @@ -93237,8 +89936,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL012W" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - pubmed: "16835446" - sbo: "SBO:0000176" @@ -93257,8 +89955,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL012W" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - pubmed: "16835446" - sbo: "SBO:0000176" @@ -93277,8 +89974,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR020C" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - pubmed: "15632184" - sbo: "SBO:0000176" @@ -93297,8 +89993,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR020C" - eccodes: "3.1.1.13" - - subsystem: - - "Steroid biosynthesis" + - subsystem: "Steroid biosynthesis" - annotation: !!omap - pubmed: "15632184" - sbo: "SBO:0000176" @@ -93319,8 +90014,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93346,8 +90040,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93373,8 +90066,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93400,8 +90092,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93427,8 +90118,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93454,8 +90144,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93481,8 +90170,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93508,8 +90196,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93535,8 +90222,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93562,8 +90248,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93589,8 +90274,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93616,8 +90300,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93643,8 +90326,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93670,8 +90352,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93697,8 +90378,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93724,8 +90404,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93751,8 +90430,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93778,8 +90456,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93805,8 +90482,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93832,8 +90508,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93859,8 +90534,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93886,8 +90560,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93913,8 +90586,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93940,8 +90612,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93967,8 +90638,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -93994,8 +90664,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94021,8 +90690,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94048,8 +90716,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94075,8 +90742,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94102,8 +90768,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94129,8 +90794,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94156,8 +90820,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94181,8 +90844,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94202,8 +90864,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR068W or YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94223,8 +90884,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94244,8 +90904,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94265,8 +90924,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94286,8 +90944,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94307,8 +90964,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94328,8 +90984,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94349,8 +91004,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR058C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94370,8 +91024,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR058C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94391,8 +91044,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR058C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94412,8 +91064,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR058C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94433,8 +91084,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL094W" - eccodes: "3.1.1.23" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94454,8 +91104,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL094W" - eccodes: "3.1.1.23" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94475,8 +91124,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL094W" - eccodes: "3.1.1.23" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94496,8 +91144,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL094W" - eccodes: "3.1.1.23" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "22345606" @@ -94516,8 +91163,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "20016004" @@ -94536,8 +91182,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "20016004" @@ -94556,8 +91201,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "20016004" @@ -94576,8 +91220,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR313C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: "sce00561" - pubmed: "20016004" @@ -94597,8 +91240,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94622,8 +91264,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94647,8 +91288,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94672,8 +91312,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94697,8 +91336,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94722,8 +91360,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94747,8 +91384,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94772,8 +91408,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94797,8 +91432,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94822,8 +91456,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94847,8 +91480,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94872,8 +91504,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94897,8 +91528,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94922,8 +91552,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94947,8 +91576,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94972,8 +91600,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKR089C" - eccodes: "3.1.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.pathway: - "sce00100" @@ -94995,8 +91622,7 @@ - s_3624: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.55 @@ -95013,8 +91639,7 @@ - s_3625: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.55 @@ -95031,8 +91656,7 @@ - s_3626: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.55 @@ -95049,8 +91673,7 @@ - s_3627: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.55 @@ -95067,8 +91690,7 @@ - s_3628: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.55 @@ -95085,8 +91707,7 @@ - s_3629: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.55 @@ -95103,8 +91724,7 @@ - s_3630: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.55 @@ -95121,8 +91741,7 @@ - s_3631: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.55 @@ -95139,8 +91758,7 @@ - s_3616: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.46 @@ -95157,8 +91775,7 @@ - s_3617: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.46 @@ -95175,8 +91792,7 @@ - s_3618: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.46 @@ -95193,8 +91809,7 @@ - s_3619: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.46 @@ -95211,8 +91826,7 @@ - s_3620: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.46 @@ -95229,8 +91843,7 @@ - s_3621: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.46 @@ -95247,8 +91860,7 @@ - s_3622: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.46 @@ -95265,8 +91877,7 @@ - s_3623: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.46 @@ -95284,8 +91895,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95305,8 +91915,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95326,8 +91935,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95347,8 +91955,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95368,8 +91975,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95389,8 +91995,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95410,8 +92015,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95431,8 +92035,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95452,8 +92055,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95473,8 +92075,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95494,8 +92095,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95515,8 +92115,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95536,8 +92135,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95557,8 +92155,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95578,8 +92175,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95599,8 +92195,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95620,8 +92215,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95641,8 +92235,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95662,8 +92255,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95683,8 +92275,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95704,8 +92295,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95725,8 +92315,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95746,8 +92335,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95767,8 +92355,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95788,8 +92375,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95809,8 +92395,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95830,8 +92415,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95851,8 +92435,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95872,8 +92455,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95893,8 +92475,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95914,8 +92495,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95935,8 +92515,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95956,8 +92535,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95977,8 +92555,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -95998,8 +92575,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96019,8 +92595,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96040,8 +92615,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96061,8 +92635,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96082,8 +92655,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96103,8 +92675,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96124,8 +92695,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96145,8 +92715,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96166,8 +92735,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96187,8 +92755,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96208,8 +92775,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96229,8 +92795,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96250,8 +92815,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96271,8 +92835,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96292,8 +92855,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96313,8 +92875,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96334,8 +92895,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96355,8 +92915,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96376,8 +92935,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96397,8 +92955,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96418,8 +92975,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96439,8 +92995,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96460,8 +93015,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96481,8 +93035,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96502,8 +93055,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96523,8 +93075,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96544,8 +93095,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96565,8 +93115,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96586,8 +93135,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96607,8 +93155,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96628,8 +93175,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96649,8 +93195,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96670,8 +93215,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96691,8 +93235,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96712,8 +93255,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96733,8 +93275,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96754,8 +93295,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96775,8 +93315,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96796,8 +93335,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96817,8 +93355,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96838,8 +93375,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96859,8 +93395,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96880,8 +93415,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96901,8 +93435,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96922,8 +93455,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96943,8 +93475,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR072C" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96964,8 +93495,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -96985,8 +93515,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97006,8 +93535,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97027,8 +93555,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97048,8 +93575,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97069,8 +93595,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97090,8 +93615,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97111,8 +93635,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97132,8 +93655,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97153,8 +93675,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97174,8 +93695,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97195,8 +93715,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97216,8 +93735,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97237,8 +93755,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97258,8 +93775,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97279,8 +93795,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97300,8 +93815,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97321,8 +93835,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97342,8 +93855,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97363,8 +93875,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97384,8 +93895,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97405,8 +93915,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97426,8 +93935,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97447,8 +93955,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97468,8 +93975,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97489,8 +93995,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97510,8 +94015,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97531,8 +94035,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97552,8 +94055,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97573,8 +94075,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97594,8 +94095,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97615,8 +94115,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97636,8 +94135,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97657,8 +94155,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97678,8 +94175,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97699,8 +94195,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97720,8 +94215,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97741,8 +94235,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97762,8 +94255,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97783,8 +94275,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97804,8 +94295,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97825,8 +94315,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97846,8 +94335,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97867,8 +94355,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97888,8 +94375,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97909,8 +94395,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97930,8 +94415,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97951,8 +94435,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97972,8 +94455,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -97993,8 +94475,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98014,8 +94495,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98035,8 +94515,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98056,8 +94535,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98077,8 +94555,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98098,8 +94575,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98119,8 +94595,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98140,8 +94615,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98161,8 +94635,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98182,8 +94655,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98203,8 +94675,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98224,8 +94695,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98245,8 +94715,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98266,8 +94735,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98287,8 +94755,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98308,8 +94775,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98329,8 +94795,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98350,8 +94815,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98371,8 +94835,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98392,8 +94855,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98413,8 +94875,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98434,8 +94895,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98455,8 +94915,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98476,8 +94935,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98497,8 +94955,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98518,8 +94975,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98539,8 +94995,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98560,8 +95015,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98581,8 +95035,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98602,8 +95055,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98623,8 +95075,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR367W and YKL004W" - eccodes: "2.-.-.-" - - subsystem: - - "Sphingoglycolipid metabolism" + - subsystem: "Sphingoglycolipid metabolism" - annotation: !!omap - pubmed: - "18296751" @@ -98640,8 +95091,7 @@ - s_2832: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR135773" - sbo: "SBO:0000655" @@ -98655,8 +95105,7 @@ - s_2835: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR128297" - sbo: "SBO:0000655" @@ -98670,8 +95119,7 @@ - s_2836: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR99101" - sbo: "SBO:0000655" @@ -98685,8 +95133,7 @@ - s_2837: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 2.49 @@ -98699,8 +95146,7 @@ - s_2838: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR99109" - sbo: "SBO:0000655" @@ -98714,8 +95160,7 @@ - s_2839: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR99110" - sbo: "SBO:0000655" @@ -98729,8 +95174,7 @@ - s_2782: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 7.42 @@ -98743,8 +95187,7 @@ - s_2781: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 7.34 @@ -98757,8 +95200,7 @@ - s_2787: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 7.66 @@ -98771,8 +95213,7 @@ - s_2789: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR103046" - sbo: "SBO:0000655" @@ -98786,8 +95227,7 @@ - s_2877: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 7.82 @@ -98800,8 +95240,7 @@ - s_2791: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR104598" - sbo: "SBO:0000655" @@ -98815,8 +95254,7 @@ - s_2821: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR128426" - sbo: "SBO:0000655" @@ -98830,8 +95268,7 @@ - s_2878: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 8.61 @@ -98844,8 +95281,7 @@ - s_2880: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 8.93 @@ -98858,8 +95294,7 @@ - s_2797: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR137463" - sbo: "SBO:0000655" @@ -98873,8 +95308,7 @@ - s_2816: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR124347" - sbo: "SBO:0000655" @@ -98888,8 +95322,7 @@ - s_2783: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR100765" - sbo: "SBO:0000655" @@ -98904,8 +95337,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YLL052C or YPR192W" - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR98641" - sbo: "SBO:0000655" @@ -98919,8 +95351,7 @@ - s_2784: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR96810" - sbo: "SBO:0000655" @@ -98934,8 +95365,7 @@ - s_2785: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR96815" - sbo: "SBO:0000655" @@ -98949,8 +95379,7 @@ - s_2799: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR101894" - sbo: "SBO:0000655" @@ -98964,8 +95393,7 @@ - s_2800: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR101896" - sbo: "SBO:0000655" @@ -98979,8 +95407,7 @@ - s_2817: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR102090" - sbo: "SBO:0000655" @@ -98994,8 +95421,7 @@ - s_2818: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR101881" - sbo: "SBO:0000655" @@ -99009,8 +95435,7 @@ - s_2820: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR101900" - sbo: "SBO:0000655" @@ -99024,8 +95449,7 @@ - s_2934: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR100308" - sbo: "SBO:0000655" @@ -99039,8 +95463,7 @@ - s_2939: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR97366" - sbo: "SBO:0000655" @@ -99054,8 +95477,7 @@ - s_2834: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR103112" - sbo: "SBO:0000655" @@ -99069,8 +95491,7 @@ - s_2966: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR102871" - sbo: "SBO:0000655" @@ -99084,8 +95505,7 @@ - s_3083: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR96946" - sbo: "SBO:0000655" @@ -99099,8 +95519,7 @@ - s_3215: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR96562" - sbo: "SBO:0000655" @@ -99114,8 +95533,7 @@ - s_3108: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR96806" - sbo: "SBO:0000655" @@ -99129,8 +95547,7 @@ - s_3216: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 2.2 @@ -99143,8 +95560,7 @@ - s_3217: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR105436" - sbo: "SBO:0000655" @@ -99158,8 +95574,7 @@ - s_2831: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR96140" - sbo: "SBO:0000655" @@ -99173,8 +95588,7 @@ - s_2833: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR95830" - sbo: "SBO:0000655" @@ -99189,8 +95603,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YKR039W" - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR104354" - sbo: "SBO:0000655" @@ -99204,8 +95617,7 @@ - s_3117: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR100848" - sbo: "SBO:0000655" @@ -99219,8 +95631,7 @@ - s_3182: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR95809" - sbo: "SBO:0000655" @@ -99234,8 +95645,7 @@ - s_3183: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR95626" - sbo: "SBO:0000655" @@ -99249,8 +95659,7 @@ - s_3432: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR97944" - sbo: "SBO:0000655" @@ -99264,8 +95673,7 @@ - s_3435: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR99529" - sbo: "SBO:0000655" @@ -99279,8 +95687,7 @@ - s_3438: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR101014" - sbo: "SBO:0000655" @@ -99294,8 +95701,7 @@ - s_3441: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR97950" - sbo: "SBO:0000655" @@ -99309,8 +95715,7 @@ - s_3444: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR105285" - sbo: "SBO:0000655" @@ -99324,8 +95729,7 @@ - s_3497: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 5.22 @@ -99338,8 +95742,7 @@ - s_3500: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 5.07 @@ -99352,8 +95755,7 @@ - s_3502: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 5.54 @@ -99366,8 +95768,7 @@ - s_3504: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 5.38 @@ -99380,8 +95781,7 @@ - s_3506: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 5.54 @@ -99394,8 +95794,7 @@ - s_3508: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 5.38 @@ -99408,8 +95807,7 @@ - s_3510: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 5.86 @@ -99422,8 +95820,7 @@ - s_3512: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 5.7 @@ -99436,8 +95833,7 @@ - s_3545: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.21 @@ -99450,8 +95846,7 @@ - s_3547: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.05 @@ -99464,8 +95859,7 @@ - s_3549: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.53 @@ -99478,8 +95872,7 @@ - s_3551: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.37 @@ -99492,8 +95885,7 @@ - s_3553: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.53 @@ -99506,8 +95898,7 @@ - s_3555: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.37 @@ -99520,8 +95911,7 @@ - s_3557: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.84 @@ -99534,8 +95924,7 @@ - s_3559: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.68 @@ -99548,8 +95937,7 @@ - s_3447: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR99874" - sbo: "SBO:0000655" @@ -99563,8 +95951,7 @@ - s_2846: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR99101" - sbo: "SBO:0000655" @@ -99578,8 +95965,7 @@ - s_2848: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99592,8 +95978,7 @@ - s_2850: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR99109" - sbo: "SBO:0000655" @@ -99607,8 +95992,7 @@ - s_2852: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR99110" - sbo: "SBO:0000655" @@ -99622,8 +96006,7 @@ - s_2843: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99636,8 +96019,7 @@ - s_2845: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99650,8 +96032,7 @@ - s_2847: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR103046" - sbo: "SBO:0000655" @@ -99665,8 +96046,7 @@ - s_2877: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99679,8 +96059,7 @@ - s_2851: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR104598" - sbo: "SBO:0000655" @@ -99694,8 +96073,7 @@ - s_2853: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR128426" - sbo: "SBO:0000655" @@ -99709,8 +96087,7 @@ - s_0769: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR100308" - sbo: "SBO:0000655" @@ -99724,8 +96101,7 @@ - s_0631: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR97366" - sbo: "SBO:0000655" @@ -99739,8 +96115,7 @@ - s_2952: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR101894" - sbo: "SBO:0000655" @@ -99754,8 +96129,7 @@ - s_2953: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR101896" - sbo: "SBO:0000655" @@ -99769,8 +96143,7 @@ - s_2840: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR96140" - sbo: "SBO:0000655" @@ -99784,8 +96157,7 @@ - s_2842: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR95830" - sbo: "SBO:0000655" @@ -99799,8 +96171,7 @@ - s_0635: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR103112" - sbo: "SBO:0000655" @@ -99814,8 +96185,7 @@ - s_3497: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99828,8 +96198,7 @@ - s_3500: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99842,8 +96211,7 @@ - s_3502: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99856,8 +96224,7 @@ - s_3504: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99870,8 +96237,7 @@ - s_3506: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99884,8 +96250,7 @@ - s_3508: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99898,8 +96263,7 @@ - s_3510: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99912,8 +96276,7 @@ - s_3512: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99926,8 +96289,7 @@ - s_3657: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR98641" - sbo: "SBO:0000655" @@ -99941,8 +96303,7 @@ - s_3684: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR100343" - sbo: "SBO:0000655" @@ -99956,8 +96317,7 @@ - s_2880: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -99970,8 +96330,7 @@ - s_2874: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR137463" - sbo: "SBO:0000655" @@ -99985,8 +96344,7 @@ - s_2876: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR124347" - sbo: "SBO:0000655" @@ -100000,8 +96358,7 @@ - s_2856: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR96140" - sbo: "SBO:0000655" @@ -100015,8 +96372,7 @@ - s_3324: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR95484" - sbo: "SBO:0000655" @@ -100030,8 +96386,7 @@ - s_0794: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR100765" - sbo: "SBO:0000655" @@ -100046,8 +96401,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YLL052C or YLL053C or YPR192W" - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR98641" - sbo: "SBO:0000655" @@ -100062,8 +96416,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCR037C or YJL198W or YML123C" - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR102871" - sbo: "SBO:0000655" @@ -100078,8 +96431,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCR098C" - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR99874" - sbo: "SBO:0000655" @@ -100094,8 +96446,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCR098C" - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR99888" - sbo: "SBO:0000655" @@ -100109,8 +96460,7 @@ - s_3463: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR99101" - sbo: "SBO:0000655" @@ -100124,8 +96474,7 @@ - s_3451: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 5.42 @@ -100138,8 +96487,7 @@ - s_3464: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR99109" - sbo: "SBO:0000655" @@ -100153,8 +96501,7 @@ - s_3459: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR99110" - sbo: "SBO:0000655" @@ -100168,8 +96515,7 @@ - s_2878: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10.5 @@ -100182,8 +96528,7 @@ - s_2880: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 11.27 @@ -100196,8 +96541,7 @@ - s_2865: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR137463" - sbo: "SBO:0000655" @@ -100211,8 +96555,7 @@ - s_2867: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - metanetx.reaction: "MNXR124347" - sbo: "SBO:0000655" @@ -100226,8 +96569,7 @@ - s_3496: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 9.6 @@ -100240,8 +96582,7 @@ - s_3499: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 9.21 @@ -100254,8 +96595,7 @@ - s_3501: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10.37 @@ -100268,8 +96608,7 @@ - s_3503: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 9.99 @@ -100282,8 +96621,7 @@ - s_3505: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10.37 @@ -100296,8 +96634,7 @@ - s_3507: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 9.99 @@ -100310,8 +96647,7 @@ - s_3509: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 11.15 @@ -100324,8 +96660,7 @@ - s_3511: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10.76 @@ -100338,8 +96673,7 @@ - s_3576: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 12.84 @@ -100352,8 +96686,7 @@ - s_3577: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 12.46 @@ -100366,8 +96699,7 @@ - s_3578: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 13.62 @@ -100380,8 +96712,7 @@ - s_3579: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 13.23 @@ -100394,8 +96725,7 @@ - s_3580: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 13.62 @@ -100408,8 +96738,7 @@ - s_3581: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 13.23 @@ -100422,8 +96751,7 @@ - s_3582: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 14.39 @@ -100436,8 +96764,7 @@ - s_3583: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, ce]" + - subsystem: "Transport [c, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 14.01 @@ -100450,8 +96777,7 @@ - s_3496: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 7.87 @@ -100464,8 +96790,7 @@ - s_3499: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 7.48 @@ -100478,8 +96803,7 @@ - s_3501: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 8.64 @@ -100492,8 +96816,7 @@ - s_3503: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 8.26 @@ -100506,8 +96829,7 @@ - s_3505: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 8.64 @@ -100520,8 +96842,7 @@ - s_3507: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 8.26 @@ -100534,8 +96855,7 @@ - s_3509: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 9.42 @@ -100548,8 +96868,7 @@ - s_3511: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 9.03 @@ -100562,8 +96881,7 @@ - s_3513: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 12.77 @@ -100576,8 +96894,7 @@ - s_3514: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 12.39 @@ -100590,8 +96907,7 @@ - s_3515: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 13.55 @@ -100604,8 +96920,7 @@ - s_3516: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 13.16 @@ -100618,8 +96933,7 @@ - s_3517: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 13.55 @@ -100632,8 +96946,7 @@ - s_3518: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 13.16 @@ -100646,8 +96959,7 @@ - s_3519: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 14.32 @@ -100660,8 +96972,7 @@ - s_3520: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 13.93 @@ -100674,8 +96985,7 @@ - s_2976: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - metanetx.reaction: "MNXR98641" - sbo: "SBO:0000655" @@ -100690,8 +97000,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNR013C" - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - metanetx.reaction: "MNXR102871" - sbo: "SBO:0000655" @@ -100705,8 +97014,7 @@ - s_3164: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - metanetx.reaction: "MNXR100765" - sbo: "SBO:0000655" @@ -100720,8 +97028,7 @@ - s_3341: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - metanetx.reaction: "MNXR96140" - sbo: "SBO:0000655" @@ -100735,8 +97042,7 @@ - s_3342: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - metanetx.reaction: "MNXR95484" - sbo: "SBO:0000655" @@ -100750,8 +97056,7 @@ - s_3165: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - metanetx.reaction: "MNXR96810" - sbo: "SBO:0000655" @@ -100765,8 +97070,7 @@ - s_3600: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 94.06 @@ -100779,8 +97083,7 @@ - s_3601: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 91.41 @@ -100793,8 +97096,7 @@ - s_3602: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 99.36 @@ -100807,8 +97109,7 @@ - s_3603: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 96.71 @@ -100821,8 +97122,7 @@ - s_3604: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 99.36 @@ -100835,8 +97135,7 @@ - s_3605: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 96.71 @@ -100849,8 +97148,7 @@ - s_3606: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 104.66 @@ -100863,8 +97161,7 @@ - s_3607: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, vm]" + - subsystem: "Transport [c, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 102.01 @@ -100877,8 +97174,7 @@ - s_2994: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, gm]" + - subsystem: "Transport [c, gm]" - annotation: !!omap - metanetx.reaction: "MNXR98641" - sbo: "SBO:0000655" @@ -100892,8 +97188,7 @@ - s_2995: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, gm]" + - subsystem: "Transport [c, gm]" - annotation: !!omap - metanetx.reaction: "MNXR102871" - sbo: "SBO:0000655" @@ -100907,8 +97202,7 @@ - s_3146: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, gm]" + - subsystem: "Transport [c, gm]" - annotation: !!omap - metanetx.reaction: "MNXR100765" - sbo: "SBO:0000655" @@ -100922,8 +97216,7 @@ - s_3147: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, gm]" + - subsystem: "Transport [c, gm]" - annotation: !!omap - metanetx.reaction: "MNXR96810" - sbo: "SBO:0000655" @@ -100937,8 +97230,7 @@ - s_3359: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, gm]" + - subsystem: "Transport [c, gm]" - annotation: !!omap - metanetx.reaction: "MNXR96140" - sbo: "SBO:0000655" @@ -100952,8 +97244,7 @@ - s_3360: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, gm]" + - subsystem: "Transport [c, gm]" - annotation: !!omap - metanetx.reaction: "MNXR95484" - sbo: "SBO:0000655" @@ -100967,8 +97258,7 @@ - s_3226: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - metanetx.reaction: "MNXR98641" - sbo: "SBO:0000655" @@ -100982,8 +97272,7 @@ - s_3129: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - metanetx.reaction: "MNXR96810" - sbo: "SBO:0000655" @@ -100997,8 +97286,7 @@ - s_3320: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 40.9 @@ -101011,8 +97299,7 @@ - s_3322: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - metanetx.reaction: "MNXR128426" - sbo: "SBO:0000655" @@ -101026,8 +97313,7 @@ - s_3521: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -44.99 @@ -101040,8 +97326,7 @@ - s_3522: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -43.63 @@ -101054,8 +97339,7 @@ - s_3523: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -47.72 @@ -101068,8 +97352,7 @@ - s_3524: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -46.35 @@ -101082,8 +97365,7 @@ - s_3525: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -47.72 @@ -101096,8 +97378,7 @@ - s_3526: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -46.35 @@ -101110,8 +97391,7 @@ - s_3271: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - metanetx.reaction: "MNXR99101" - sbo: "SBO:0000655" @@ -101125,8 +97405,7 @@ - s_3277: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - metanetx.reaction: "MNXR99109" - sbo: "SBO:0000655" @@ -101141,8 +97420,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YHR002W" - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - metanetx.reaction: "MNXR96815" - sbo: "SBO:0000655" @@ -101156,8 +97434,7 @@ - s_2841: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - metanetx.reaction: "MNXR135773" - sbo: "SBO:0000655" @@ -101171,8 +97448,7 @@ - s_2844: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - metanetx.reaction: "MNXR128297" - sbo: "SBO:0000655" @@ -101186,8 +97462,7 @@ - s_2873: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - metanetx.reaction: "MNXR128298" - sbo: "SBO:0000655" @@ -101201,8 +97476,7 @@ - s_2875: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - metanetx.reaction: "MNXR136128" - sbo: "SBO:0000655" @@ -101216,8 +97490,7 @@ - s_3044: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.6 @@ -101230,8 +97503,7 @@ - s_3059: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.44 @@ -101244,8 +97516,7 @@ - s_3067: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.92 @@ -101258,8 +97529,7 @@ - s_3075: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.76 @@ -101272,8 +97542,7 @@ - s_3048: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.44 @@ -101286,8 +97555,7 @@ - s_3061: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.28 @@ -101300,8 +97568,7 @@ - s_3069: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.76 @@ -101314,8 +97581,7 @@ - s_3077: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.6 @@ -101328,8 +97594,7 @@ - s_3052: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.92 @@ -101342,8 +97607,7 @@ - s_3063: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.76 @@ -101356,8 +97620,7 @@ - s_3071: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.23 @@ -101370,8 +97633,7 @@ - s_3079: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.07 @@ -101384,8 +97646,7 @@ - s_3056: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.76 @@ -101398,8 +97659,7 @@ - s_3065: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.6 @@ -101412,8 +97672,7 @@ - s_3073: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.07 @@ -101426,8 +97685,7 @@ - s_3081: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.92 @@ -101440,8 +97698,7 @@ - s_3046: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.92 @@ -101454,8 +97711,7 @@ - s_3060: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.76 @@ -101468,8 +97724,7 @@ - s_3068: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.23 @@ -101482,8 +97737,7 @@ - s_3076: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.07 @@ -101496,8 +97750,7 @@ - s_3050: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.76 @@ -101510,8 +97763,7 @@ - s_3062: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.6 @@ -101524,8 +97776,7 @@ - s_3070: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.07 @@ -101538,8 +97789,7 @@ - s_3078: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.92 @@ -101552,8 +97802,7 @@ - s_3054: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.23 @@ -101566,8 +97815,7 @@ - s_3064: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.07 @@ -101580,8 +97828,7 @@ - s_3072: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.55 @@ -101594,8 +97841,7 @@ - s_3080: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.39 @@ -101608,8 +97854,7 @@ - s_3058: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.07 @@ -101622,8 +97867,7 @@ - s_3066: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -7.92 @@ -101636,8 +97880,7 @@ - s_3074: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.39 @@ -101650,8 +97893,7 @@ - s_3082: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -8.23 @@ -101664,8 +97906,7 @@ - s_3660: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - metanetx.reaction: "MNXR97944" - sbo: "SBO:0000655" @@ -101679,8 +97920,7 @@ - s_3435: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - metanetx.reaction: "MNXR99529" - sbo: "SBO:0000655" @@ -101694,8 +97934,7 @@ - s_3665: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - metanetx.reaction: "MNXR101014" - sbo: "SBO:0000655" @@ -101709,8 +97948,7 @@ - s_3444: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - metanetx.reaction: "MNXR105285" - sbo: "SBO:0000655" @@ -101724,8 +97962,7 @@ - s_3656: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -5.7 @@ -101738,8 +97975,7 @@ - s_3658: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.02 @@ -101752,8 +97988,7 @@ - s_3659: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -5.86 @@ -101766,8 +98001,7 @@ - s_3661: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.17 @@ -101780,8 +98014,7 @@ - s_3662: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -5.86 @@ -101794,8 +98027,7 @@ - s_3663: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.17 @@ -101808,8 +98040,7 @@ - s_3664: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.17 @@ -101822,8 +98053,7 @@ - s_3666: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.49 @@ -101836,8 +98066,7 @@ - s_3667: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -5.7 @@ -101850,8 +98079,7 @@ - s_3668: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.02 @@ -101864,8 +98092,7 @@ - s_3693: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.17 @@ -101878,8 +98105,7 @@ - s_3695: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.02 @@ -101892,8 +98118,7 @@ - s_3697: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.49 @@ -101906,8 +98131,7 @@ - s_3699: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.33 @@ -101920,8 +98144,7 @@ - s_3701: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.49 @@ -101934,8 +98157,7 @@ - s_3702: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.33 @@ -101948,8 +98170,7 @@ - s_3703: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.81 @@ -101962,8 +98183,7 @@ - s_3704: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.65 @@ -101976,8 +98196,7 @@ - s_3705: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -5.7 @@ -101990,8 +98209,7 @@ - s_3706: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -5.54 @@ -102004,8 +98222,7 @@ - s_3707: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.02 @@ -102018,8 +98235,7 @@ - s_3708: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -5.86 @@ -102032,8 +98248,7 @@ - s_3686: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.02 @@ -102046,8 +98261,7 @@ - s_3688: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -5.86 @@ -102060,8 +98274,7 @@ - s_3690: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.33 @@ -102074,8 +98287,7 @@ - s_3692: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -6.17 @@ -102088,8 +98300,7 @@ - s_3694: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -3.96 @@ -102102,8 +98313,7 @@ - s_3696: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -3.8 @@ -102116,8 +98326,7 @@ - s_3698: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -4.27 @@ -102130,8 +98339,7 @@ - s_3700: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -4.12 @@ -102144,8 +98352,7 @@ - s_3685: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -3.48 @@ -102158,8 +98365,7 @@ - s_3687: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -3.32 @@ -102172,8 +98378,7 @@ - s_3689: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -3.8 @@ -102186,8 +98391,7 @@ - s_3691: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -3.64 @@ -102200,8 +98404,7 @@ - s_2962: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.19 @@ -102214,8 +98417,7 @@ - s_2963: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.03 @@ -102228,8 +98430,7 @@ - s_2964: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.51 @@ -102242,8 +98443,7 @@ - s_2965: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, lp]" + - subsystem: "Transport [erm, lp]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.35 @@ -102256,8 +98456,7 @@ - s_3092: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 38.46 @@ -102270,8 +98469,7 @@ - s_3097: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 37.25 @@ -102284,8 +98482,7 @@ - s_3099: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 40.87 @@ -102298,8 +98495,7 @@ - s_3101: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 39.66 @@ -102312,8 +98508,7 @@ - s_3103: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 40.87 @@ -102326,8 +98521,7 @@ - s_3105: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 39.66 @@ -102340,8 +98534,7 @@ - s_3128: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 42.59 @@ -102354,8 +98547,7 @@ - s_3131: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 41.38 @@ -102368,8 +98560,7 @@ - s_3133: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 45 @@ -102382,8 +98573,7 @@ - s_3135: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 43.79 @@ -102396,8 +98586,7 @@ - s_3137: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 45 @@ -102410,8 +98599,7 @@ - s_3139: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 43.79 @@ -102424,8 +98612,7 @@ - s_3141: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 47.41 @@ -102438,8 +98625,7 @@ - s_3143: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 46.2 @@ -102452,8 +98638,7 @@ - s_3181: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -43.38 @@ -102466,8 +98651,7 @@ - s_3185: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -42.18 @@ -102480,8 +98664,7 @@ - s_3187: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -45.79 @@ -102494,8 +98677,7 @@ - s_3189: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -44.59 @@ -102508,8 +98690,7 @@ - s_3191: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -45.79 @@ -102522,8 +98703,7 @@ - s_3193: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -44.59 @@ -102536,8 +98716,7 @@ - s_3195: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -48.2 @@ -102550,8 +98729,7 @@ - s_3197: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -47 @@ -102564,8 +98742,7 @@ - s_3296: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 47 @@ -102578,8 +98755,7 @@ - s_3298: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 45.79 @@ -102592,8 +98768,7 @@ - s_3300: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 49.41 @@ -102606,8 +98781,7 @@ - s_3302: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 48.2 @@ -102620,8 +98794,7 @@ - s_3304: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 49.41 @@ -102634,8 +98807,7 @@ - s_3305: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 48.2 @@ -102648,8 +98820,7 @@ - s_3306: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 51.82 @@ -102662,8 +98833,7 @@ - s_3307: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, mm]" + - subsystem: "Transport [erm, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 50.61 @@ -102676,8 +98846,7 @@ - s_2996: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -76.48 @@ -102690,8 +98859,7 @@ - s_3000: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -74.17 @@ -102704,8 +98872,7 @@ - s_3004: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -81.12 @@ -102718,8 +98885,7 @@ - s_3008: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -78.8 @@ -102732,8 +98898,7 @@ - s_2998: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -81.12 @@ -102746,8 +98911,7 @@ - s_3002: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -78.8 @@ -102760,8 +98924,7 @@ - s_3006: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -85.75 @@ -102774,8 +98937,7 @@ - s_3010: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -83.44 @@ -102788,8 +98950,7 @@ - s_2993: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -75.65 @@ -102802,8 +98963,7 @@ - s_2999: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -73.33 @@ -102816,8 +98976,7 @@ - s_3003: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -80.29 @@ -102830,8 +98989,7 @@ - s_3007: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -77.97 @@ -102844,8 +99002,7 @@ - s_2997: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -80.29 @@ -102858,8 +99015,7 @@ - s_3001: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -77.97 @@ -102872,8 +99028,7 @@ - s_3005: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -84.92 @@ -102886,8 +99041,7 @@ - s_3009: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -82.6 @@ -102900,8 +99054,7 @@ - s_3358: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -88.07 @@ -102914,8 +99067,7 @@ - s_3362: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -85.75 @@ -102928,8 +99080,7 @@ - s_3364: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -92.71 @@ -102942,8 +99093,7 @@ - s_3366: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -90.39 @@ -102956,8 +99106,7 @@ - s_3368: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -92.71 @@ -102970,8 +99119,7 @@ - s_3370: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -90.39 @@ -102984,8 +99132,7 @@ - s_3372: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -97.34 @@ -102998,8 +99145,7 @@ - s_3374: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -95.02 @@ -103013,8 +99159,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W or YMR162C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -82.28 @@ -103028,8 +99173,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W or YMR162C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -79.96 @@ -103043,8 +99187,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W or YMR162C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -86.91 @@ -103058,8 +99201,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W or YMR162C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -84.6 @@ -103073,8 +99215,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W or YMR162C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -86.91 @@ -103088,8 +99229,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W or YMR162C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -84.6 @@ -103103,8 +99243,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W or YMR162C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -91.55 @@ -103118,8 +99257,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W or YMR162C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -89.23 @@ -103133,8 +99271,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 83.44 @@ -103148,8 +99285,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 81.12 @@ -103163,8 +99299,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 88.07 @@ -103178,8 +99313,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 85.75 @@ -103193,8 +99327,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 88.07 @@ -103208,8 +99341,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 85.75 @@ -103223,8 +99355,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 92.71 @@ -103238,8 +99369,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [erm, gm]" + - subsystem: "Transport [erm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 90.39 @@ -103252,8 +99382,7 @@ - s_2975: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -91.74 @@ -103266,8 +99395,7 @@ - s_2981: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -88.93 @@ -103280,8 +99408,7 @@ - s_2985: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -97.35 @@ -103294,8 +99421,7 @@ - s_2989: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -94.54 @@ -103308,8 +99434,7 @@ - s_2979: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -97.35 @@ -103322,8 +99447,7 @@ - s_2983: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -94.54 @@ -103336,8 +99460,7 @@ - s_2987: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -102.97 @@ -103350,8 +99473,7 @@ - s_2991: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -100.16 @@ -103364,8 +99486,7 @@ - s_3340: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -106.72 @@ -103378,8 +99499,7 @@ - s_3344: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -103.91 @@ -103392,8 +99512,7 @@ - s_3346: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -112.34 @@ -103406,8 +99525,7 @@ - s_3348: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -109.53 @@ -103420,8 +99538,7 @@ - s_3350: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -112.34 @@ -103434,8 +99551,7 @@ - s_3352: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -109.53 @@ -103448,8 +99564,7 @@ - s_3354: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -117.96 @@ -103462,8 +99577,7 @@ - s_3356: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -115.15 @@ -103476,8 +99590,7 @@ - s_3163: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -99.7 @@ -103490,8 +99603,7 @@ - s_3167: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -96.89 @@ -103504,8 +99616,7 @@ - s_3169: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -105.32 @@ -103518,8 +99629,7 @@ - s_3171: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -102.51 @@ -103532,8 +99642,7 @@ - s_3173: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -105.32 @@ -103546,8 +99655,7 @@ - s_3175: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -102.51 @@ -103560,8 +99668,7 @@ - s_3177: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -110.93 @@ -103574,8 +99681,7 @@ - s_3179: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -108.13 @@ -103588,8 +99694,7 @@ - s_3181: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 101.11 @@ -103602,8 +99707,7 @@ - s_3185: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 98.3 @@ -103616,8 +99720,7 @@ - s_3187: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 106.72 @@ -103630,8 +99733,7 @@ - s_3189: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 103.91 @@ -103644,8 +99746,7 @@ - s_3191: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 106.72 @@ -103658,8 +99759,7 @@ - s_3193: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 103.91 @@ -103672,8 +99772,7 @@ - s_3195: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 112.34 @@ -103686,8 +99785,7 @@ - s_3197: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 109.53 @@ -103700,8 +99798,7 @@ - s_3560: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 105.69 @@ -103714,8 +99811,7 @@ - s_3561: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 102.88 @@ -103728,8 +99824,7 @@ - s_3562: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 111.3 @@ -103742,8 +99837,7 @@ - s_3563: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 108.5 @@ -103756,8 +99850,7 @@ - s_3564: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 111.3 @@ -103770,8 +99863,7 @@ - s_3565: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 108.5 @@ -103784,8 +99876,7 @@ - s_3566: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 116.92 @@ -103798,8 +99889,7 @@ - s_3567: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, vm]" + - subsystem: "Transport [erm, vm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 114.11 @@ -103812,8 +99902,7 @@ - s_3323: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.72 @@ -103826,8 +99915,7 @@ - s_3326: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.18 @@ -103840,8 +99928,7 @@ - s_3328: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.81 @@ -103854,8 +99941,7 @@ - s_3330: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.27 @@ -103868,8 +99954,7 @@ - s_3332: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.81 @@ -103882,8 +99967,7 @@ - s_3334: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.27 @@ -103896,8 +99980,7 @@ - s_3336: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -22.9 @@ -103910,8 +99993,7 @@ - s_3338: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -22.36 @@ -103924,8 +100006,7 @@ - s_3448: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.27 @@ -103938,8 +100019,7 @@ - s_3452: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.72 @@ -103952,8 +100032,7 @@ - s_3454: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -22.36 @@ -103966,8 +100045,7 @@ - s_3456: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.81 @@ -103980,8 +100058,7 @@ - s_3458: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -22.36 @@ -103994,8 +100071,7 @@ - s_3460: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.81 @@ -104008,8 +100084,7 @@ - s_3461: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -23.45 @@ -104022,8 +100097,7 @@ - s_3462: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -22.9 @@ -104037,8 +100111,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -19.63 @@ -104052,8 +100125,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -19.09 @@ -104067,8 +100139,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.72 @@ -104082,8 +100153,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.18 @@ -104097,8 +100167,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.72 @@ -104112,8 +100181,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.18 @@ -104127,8 +100195,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.81 @@ -104142,8 +100209,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YAL026C" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.27 @@ -104157,8 +100223,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -19.36 @@ -104172,8 +100237,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -18.81 @@ -104187,8 +100251,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.45 @@ -104202,8 +100265,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -19.9 @@ -104217,8 +100279,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.45 @@ -104232,8 +100293,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -19.9 @@ -104247,8 +100307,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.54 @@ -104262,8 +100321,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL048W" - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21 @@ -104276,8 +100334,7 @@ - s_2869: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - metanetx.reaction: "MNXR128298" - sbo: "SBO:0000655" @@ -104291,8 +100348,7 @@ - s_2870: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - metanetx.reaction: "MNXR136128" - sbo: "SBO:0000655" @@ -104306,8 +100362,7 @@ - s_3527: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 17.76 @@ -104320,8 +100375,7 @@ - s_3528: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 17.22 @@ -104334,8 +100388,7 @@ - s_3529: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 18.85 @@ -104348,8 +100401,7 @@ - s_3530: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 18.31 @@ -104362,8 +100414,7 @@ - s_3531: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 18.85 @@ -104376,8 +100427,7 @@ - s_3532: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 18.31 @@ -104390,8 +100440,7 @@ - s_3533: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 19.95 @@ -104404,8 +100453,7 @@ - s_3534: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 19.4 @@ -104418,8 +100466,7 @@ - s_3584: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 20.48 @@ -104432,8 +100479,7 @@ - s_3585: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 19.93 @@ -104446,8 +100492,7 @@ - s_3586: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 21.57 @@ -104460,8 +100505,7 @@ - s_3587: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 21.03 @@ -104474,8 +100518,7 @@ - s_3588: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 21.57 @@ -104488,8 +100531,7 @@ - s_3589: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 21.03 @@ -104502,8 +100544,7 @@ - s_3590: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 22.66 @@ -104516,8 +100557,7 @@ - s_3591: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 22.12 @@ -104530,8 +100570,7 @@ - s_3608: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 20.22 @@ -104544,8 +100583,7 @@ - s_3609: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 19.68 @@ -104558,8 +100596,7 @@ - s_3610: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 21.31 @@ -104572,8 +100609,7 @@ - s_3611: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 20.77 @@ -104586,8 +100622,7 @@ - s_3612: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 21.31 @@ -104600,8 +100635,7 @@ - s_3613: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 20.77 @@ -104614,8 +100648,7 @@ - s_3614: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 22.4 @@ -104628,8 +100661,7 @@ - s_3615: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 21.86 @@ -104642,8 +100674,7 @@ - s_3669: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -19.63 @@ -104656,8 +100687,7 @@ - s_3670: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [ce, erm]" + - subsystem: "Transport [ce, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.72 @@ -104670,8 +100700,7 @@ - s_3376: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, n]" + - subsystem: "Transport [erm, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.72 @@ -104684,8 +100713,7 @@ - s_3378: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, n]" + - subsystem: "Transport [erm, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -20.18 @@ -104698,8 +100726,7 @@ - s_3380: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, n]" + - subsystem: "Transport [erm, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.81 @@ -104712,8 +100739,7 @@ - s_3382: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, n]" + - subsystem: "Transport [erm, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.27 @@ -104726,8 +100752,7 @@ - s_3384: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, n]" + - subsystem: "Transport [erm, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.81 @@ -104740,8 +100765,7 @@ - s_3386: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, n]" + - subsystem: "Transport [erm, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -21.27 @@ -104754,8 +100778,7 @@ - s_3388: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, n]" + - subsystem: "Transport [erm, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -22.9 @@ -104768,8 +100791,7 @@ - s_3390: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, n]" + - subsystem: "Transport [erm, n]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -22.36 @@ -104782,8 +100804,7 @@ - s_2869: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, er]" + - subsystem: "Transport [erm, er]" - annotation: !!omap - metanetx.reaction: "MNXR128298" - sbo: "SBO:0000655" @@ -104797,8 +100818,7 @@ - s_2870: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, er]" + - subsystem: "Transport [erm, er]" - annotation: !!omap - metanetx.reaction: "MNXR136128" - sbo: "SBO:0000655" @@ -104812,8 +100832,7 @@ - s_3441: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [erm, er]" + - subsystem: "Transport [erm, er]" - annotation: !!omap - metanetx.reaction: "MNXR97950" - sbo: "SBO:0000655" @@ -104827,8 +100846,7 @@ - s_2966: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [erm, er]" + - subsystem: "Transport [erm, er]" - annotation: !!omap - metanetx.reaction: "MNXR102871" - sbo: "SBO:0000655" @@ -104842,8 +100860,7 @@ - s_3568: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, gm]" + - subsystem: "Transport [vm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.11 @@ -104856,8 +100873,7 @@ - s_3569: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, gm]" + - subsystem: "Transport [vm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.11 @@ -104870,8 +100886,7 @@ - s_3570: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, gm]" + - subsystem: "Transport [vm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.11 @@ -104884,8 +100899,7 @@ - s_3571: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, gm]" + - subsystem: "Transport [vm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.11 @@ -104898,8 +100912,7 @@ - s_3572: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, gm]" + - subsystem: "Transport [vm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.11 @@ -104912,8 +100925,7 @@ - s_3573: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, gm]" + - subsystem: "Transport [vm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.11 @@ -104926,8 +100938,7 @@ - s_3574: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, gm]" + - subsystem: "Transport [vm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.11 @@ -104940,8 +100951,7 @@ - s_3575: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, gm]" + - subsystem: "Transport [vm, gm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.11 @@ -104954,8 +100964,7 @@ - s_3592: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, ce]" + - subsystem: "Transport [vm, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.68 @@ -104968,8 +100977,7 @@ - s_3593: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, ce]" + - subsystem: "Transport [vm, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.68 @@ -104982,8 +100990,7 @@ - s_3594: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, ce]" + - subsystem: "Transport [vm, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.68 @@ -104996,8 +101003,7 @@ - s_3595: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, ce]" + - subsystem: "Transport [vm, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.68 @@ -105010,8 +101016,7 @@ - s_3596: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, ce]" + - subsystem: "Transport [vm, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.68 @@ -105024,8 +101029,7 @@ - s_3597: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, ce]" + - subsystem: "Transport [vm, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.68 @@ -105038,8 +101042,7 @@ - s_3598: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, ce]" + - subsystem: "Transport [vm, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.68 @@ -105052,8 +101055,7 @@ - s_3599: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [vm, ce]" + - subsystem: "Transport [vm, ce]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.68 @@ -105066,8 +101068,7 @@ - s_3094: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [m, mm]" + - subsystem: "Transport [m, mm]" - annotation: !!omap - metanetx.reaction: "MNXR100765" - sbo: "SBO:0000655" @@ -105081,8 +101082,7 @@ - s_3218: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [m, mm]" + - subsystem: "Transport [m, mm]" - annotation: !!omap - metanetx.reaction: "MNXR100308" - sbo: "SBO:0000655" @@ -105097,8 +101097,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR192W" - - subsystem: - - "Transport [m, mm]" + - subsystem: "Transport [m, mm]" - annotation: !!omap - metanetx.reaction: "MNXR96806" - sbo: "SBO:0000655" @@ -105113,8 +101112,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR192W" - - subsystem: - - "Transport [m, mm]" + - subsystem: "Transport [m, mm]" - annotation: !!omap - metanetx.reaction: "MNXR96946" - sbo: "SBO:0000655" @@ -105129,8 +101127,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YER053C or YJR077C" - - subsystem: - - "Transport [m, mm]" + - subsystem: "Transport [m, mm]" - annotation: !!omap - metanetx.reaction: "MNXR102871" - sbo: "SBO:0000655" @@ -105144,8 +101141,7 @@ - s_3095: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [m, mm]" + - subsystem: "Transport [m, mm]" - annotation: !!omap - metanetx.reaction: "MNXR103112" - sbo: "SBO:0000655" @@ -105161,8 +101157,7 @@ - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105177,8 +101172,7 @@ - s_3741: 0.508826 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105194,8 +101188,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105211,8 +101204,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105228,8 +101220,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105245,8 +101236,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105262,8 +101252,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105278,8 +101267,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105294,8 +101282,7 @@ - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105310,8 +101297,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105325,8 +101311,7 @@ - s_3709: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -105337,12 +101322,12 @@ - name: "palmitate [cytoplasm] SLIME rxn" - metabolites: !!omap - s_0694: 0.25542094 + - s_0794: -1 - s_1286: -1 - s_3740: 0.25642888 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105353,12 +101338,12 @@ - name: "palmitoleate [cytoplasm] SLIME rxn" - metabolites: !!omap - s_0694: 0.25340506 + - s_0794: -1 - s_1293: -1 - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105369,12 +101354,12 @@ - name: "stearate [cytoplasm] SLIME rxn" - metabolites: !!omap - s_0694: 0.2834747 + - s_0794: -1 - s_1449: -1 - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105385,12 +101370,12 @@ - name: "oleate [cytoplasm] SLIME rxn" - metabolites: !!omap - s_0694: 0.28145882 + - s_0794: -1 - s_1260: -1 - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105406,8 +101391,7 @@ - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105422,8 +101406,7 @@ - s_3741: 0.508826 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105439,8 +101422,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105456,8 +101438,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105473,8 +101454,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105490,8 +101470,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105507,8 +101486,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105523,8 +101501,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105538,8 +101515,7 @@ - s_3710: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR103315" - sbo: "SBO:0000655" @@ -105556,8 +101532,7 @@ - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105572,8 +101547,7 @@ - s_3741: 0.508826 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105589,8 +101563,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105606,8 +101579,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105623,8 +101595,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105640,8 +101611,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105657,8 +101627,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105673,8 +101642,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105688,8 +101656,7 @@ - s_3711: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR102406" - sbo: "SBO:0000655" @@ -105706,8 +101673,7 @@ - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105722,8 +101688,7 @@ - s_3741: 0.508826 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105739,8 +101704,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105756,8 +101720,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105773,8 +101736,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105790,8 +101752,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105807,8 +101768,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105823,8 +101783,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105838,8 +101797,7 @@ - s_3712: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR102505" - sbo: "SBO:0000655" @@ -105856,8 +101814,7 @@ - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105873,8 +101830,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105890,8 +101846,7 @@ - s_3741: 0.508826 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105908,8 +101863,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105926,8 +101880,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105944,8 +101897,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105962,8 +101914,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105979,8 +101930,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -105996,8 +101946,7 @@ - s_3741: 0.508826 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106014,8 +101963,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106030,8 +101978,7 @@ - s_3741: 0.763239 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106047,8 +101994,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106064,8 +102010,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106082,8 +102027,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106099,8 +102043,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106116,8 +102059,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106134,8 +102076,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106152,8 +102093,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106169,8 +102109,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106187,8 +102126,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106204,8 +102142,7 @@ - s_3742: 0.56896528 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106221,8 +102158,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106239,8 +102175,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106256,8 +102191,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106274,8 +102208,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106291,8 +102224,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106308,8 +102240,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106325,8 +102256,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106343,8 +102273,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106360,8 +102289,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106377,8 +102305,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106393,8 +102320,7 @@ - s_3743: 0.84740028 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106408,8 +102334,7 @@ - s_3713: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR104713" - sbo: "SBO:0000655" @@ -106428,8 +102353,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL015W" - eccodes: "3.1.2.1" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - kegg.pathway: "sce00620" - kegg.reaction: "R10343" @@ -106446,8 +102370,7 @@ - s_3714: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106459,9 +102382,11 @@ - s_0394: 55.3 - s_0434: -55.3 - s_0450: 1 - - s_0794: 55.3 + - s_0794: 52.3 - s_0803: -55.3 - s_1096: -1 + - s_1207: 3 + - s_1212: -3 - s_1322: 55.3 - s_3717: -1 - s_3718: -1 @@ -106471,8 +102396,7 @@ - s_4206: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Growth" + - subsystem: "Growth" - annotation: !!omap - sbo: "SBO:0000629" - deltaG: 10000000 @@ -106487,8 +102411,7 @@ - s_3716: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - kegg.reaction: "R02410" - metanetx.reaction: "MNXR103420" @@ -106504,8 +102427,7 @@ - s_3715: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_raffin_e" - sbo: "SBO:0000627" @@ -106518,8 +102440,7 @@ - s_3716: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_melib_e" - sbo: "SBO:0000627" @@ -106536,8 +102457,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR400W" - eccodes: "3.2.2.3" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "URIH" - kegg.pathway: @@ -106560,8 +102480,7 @@ - s_1322: 1 - lower_bound: 0.7 - upper_bound: 0.7 - - subsystem: - - "Growth" + - subsystem: "Growth" - annotation: !!omap - bigg.reaction: "ATPM" - sbo: "SBO:0000630" @@ -106571,51 +102490,51 @@ - id: "r_4047" - name: "protein pseudoreaction" - metabolites: !!omap - - s_0404: -0.527012401964609 - - s_0428: -0.184592178971158 - - s_0430: -0.116820320233205 - - s_0432: -0.341731040134025 - - s_0542: -0.00758125964441183 - - s_0747: -0.121070423838014 - - s_0748: -0.346670343714861 - - s_0757: -0.33357542435412 - - s_0832: -0.0761571964321321 - - s_0847: -0.221349807713738 - - s_1077: -0.340467492580805 - - s_1099: -0.328750973172121 - - s_1148: -0.0582378601225956 - - s_1314: -0.15380767944836 - - s_1379: -0.189186891122282 - - s_1428: -0.212964470019559 - - s_1491: -0.219856538246244 - - s_1527: -0.0326223903740585 - - s_1533: -0.117164920221219 - - s_1561: -0.303939602869103 - - s_1582: 0.527012401964609 - - s_1583: 0.184592178971158 - - s_1585: 0.116820320233205 - - s_1587: 0.341731040134025 - - s_1589: 0.00758125964441183 - - s_1590: 0.121070423838014 - - s_1591: 0.346670343714861 - - s_1593: 0.33357542435412 - - s_1594: 0.0761571964321321 - - s_1596: 0.221349807713738 - - s_1598: 0.340467492580805 - - s_1600: 0.328750973172121 - - s_1602: 0.0582378601225956 - - s_1604: 0.15380767944836 - - s_1606: 0.189186891122282 - - s_1607: 0.212964470019559 - - s_1608: 0.219856538246244 - - s_1610: 0.0326223903740585 - - s_1612: 0.117164920221219 - - s_1614: 0.303939602869103 + - s_0404: -0.347736630768556 + - s_0428: -0.194296205196944 + - s_0430: -0.191468067207859 + - s_0432: -0.240359946744132 + - s_0542: -0.0375594996568427 + - s_0747: -0.141160332291015 + - s_0748: -0.296487312016288 + - s_0757: -0.283748983111195 + - s_0794: 4.17785919150305 + - s_0832: -0.08356708763266 + - s_0847: -0.265490320174191 + - s_1077: -0.362523293945085 + - s_1099: -0.32939964005654 + - s_1148: -0.0814974664727417 + - s_1314: -0.166795958026717 + - s_1379: -0.179821149401597 + - s_1428: -0.277725658983052 + - s_1491: -0.235173028298401 + - s_1527: -0.0385698144584582 + - s_1533: -0.123025660792855 + - s_1561: -0.31460454977486 + - s_1582: 0.347736630768556 + - s_1583: 0.194296205196944 + - s_1585: 0.191468067207859 + - s_1587: 0.240359946744132 + - s_1589: 0.0375594996568427 + - s_1590: 0.141160332291015 + - s_1591: 0.296487312016288 + - s_1593: 0.283748983111195 + - s_1594: 0.08356708763266 + - s_1596: 0.265490320174191 + - s_1598: 0.362523293945085 + - s_1600: 0.32939964005654 + - s_1602: 0.0814974664727417 + - s_1604: 0.166795958026717 + - s_1606: 0.179821149401597 + - s_1607: 0.277725658983052 + - s_1608: 0.235173028298401 + - s_1610: 0.0385698144584582 + - s_1612: 0.123025660792855 + - s_1614: 0.31460454977486 - s_3717: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Growth" + - subsystem: "Growth" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106633,8 +102552,7 @@ - s_3718: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Growth" + - subsystem: "Growth" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106646,12 +102564,12 @@ - s_0423: -0.0445348319234424 - s_0526: -0.043276239184487 - s_0782: -0.0445348319234424 + - s_0794: -0.380675999881061 - s_1545: -0.0579920969091588 - s_3719: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Growth" + - subsystem: "Growth" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106664,11 +102582,11 @@ - s_0589: -0.00240000011399388 - s_0615: -0.00240000011399388 - s_0649: -0.00359999993816018 + - s_0794: -0.0240000002086162 - s_3720: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Growth" + - subsystem: "Growth" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106681,8 +102599,7 @@ - s_3722: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106696,8 +102613,7 @@ - s_3723: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106711,8 +102627,7 @@ - s_3724: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106726,8 +102641,7 @@ - s_3725: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106741,8 +102655,7 @@ - s_3727: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106756,8 +102669,7 @@ - s_3729: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106771,8 +102683,7 @@ - s_3731: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106786,8 +102697,7 @@ - s_3733: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106801,8 +102711,7 @@ - s_3735: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106816,8 +102725,7 @@ - s_3737: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106831,8 +102739,7 @@ - s_3739: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, mm]" + - subsystem: "Transport [c, mm]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -106845,8 +102752,7 @@ - s_3746: -1 - lower_bound: 0 - upper_bound: 0 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000632" - deltaG: 10000000 @@ -106866,8 +102772,7 @@ - s_3746: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106880,8 +102785,7 @@ - s_3747: -1 - lower_bound: 0 - upper_bound: 0 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000632" - deltaG: 10000000 @@ -106897,8 +102801,7 @@ - s_3747: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106914,8 +102817,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106931,8 +102833,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106948,8 +102849,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106965,8 +102865,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106982,8 +102881,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -106999,8 +102897,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107016,8 +102913,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107033,8 +102929,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107050,8 +102945,7 @@ - s_3744: 0.36864392 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107067,8 +102961,7 @@ - s_3745: 0.39669768 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107078,13 +102971,13 @@ - id: "r_4076" - name: "phytosphingosine [endoplasmic reticulum] SLIME rxn" - metabolites: !!omap + - s_0794: 1 - s_1366: -1 - s_3726: 0.3175126 - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107094,13 +102987,13 @@ - id: "r_4077" - name: "phytosphingosine 1-phosphate [endoplasmic reticulum] SLIME rxn" - metabolites: !!omap + - s_0794: -1 - s_1367: -1 - s_3728: 0.397492502 - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107110,13 +103003,13 @@ - id: "r_4078" - name: "sphinganine [endoplasmic reticulum] SLIME rxn" - metabolites: !!omap + - s_0794: 1 - s_1445: -1 - s_3726: 0.30252114 - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107126,13 +103019,13 @@ - id: "r_4079" - name: "sphinganine 1-phosphate [endoplasmic reticulum] SLIME rxn" - metabolites: !!omap + - s_0794: -1 - s_1446: -1 - s_3728: 0.380485162 - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107148,8 +103041,7 @@ - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107165,8 +103057,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107181,8 +103072,7 @@ - s_3741: 0.508826 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107198,8 +103088,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107215,8 +103104,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107232,8 +103120,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107249,8 +103136,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107265,8 +103151,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107282,8 +103167,7 @@ - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107299,8 +103183,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107315,8 +103198,7 @@ - s_3741: 0.508826 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107332,8 +103214,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107349,8 +103230,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107366,8 +103246,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107383,8 +103262,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107399,8 +103277,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107415,8 +103292,7 @@ - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107431,8 +103307,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107448,8 +103323,7 @@ - s_3741: 0.254413 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107464,8 +103338,7 @@ - s_3741: 0.508826 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107481,8 +103354,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107498,8 +103370,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107515,8 +103386,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107532,8 +103402,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107549,8 +103418,7 @@ - s_3741: 0.508826 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107566,8 +103434,7 @@ - s_3741: 0.763239 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107584,8 +103451,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107602,8 +103468,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107620,8 +103485,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107638,8 +103502,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107655,8 +103518,7 @@ - s_3741: 0.763239 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107671,8 +103533,7 @@ - s_3741: 1.017652 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107688,8 +103549,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107705,8 +103565,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107723,8 +103582,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107740,8 +103598,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107758,8 +103615,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107775,8 +103631,7 @@ - s_3742: 0.28448264 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107792,8 +103647,7 @@ - s_3742: 0.56896528 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107810,8 +103664,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107829,8 +103682,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107847,8 +103699,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107865,8 +103716,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107882,8 +103732,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107900,8 +103749,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107917,8 +103765,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107935,8 +103782,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107952,8 +103798,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107970,8 +103815,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -107988,8 +103832,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108007,8 +103850,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108025,8 +103867,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108042,8 +103883,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108060,8 +103900,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108078,8 +103917,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108095,8 +103933,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108113,8 +103950,7 @@ - s_3743: 0.28246676 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108130,8 +103966,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108148,8 +103983,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108165,8 +103999,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108183,8 +104016,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108200,8 +104032,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108218,8 +104049,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108235,8 +104065,7 @@ - s_3743: 0.84740028 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108252,8 +104081,7 @@ - s_3743: 0.84740028 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108269,8 +104097,7 @@ - s_3743: 0.84740028 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108287,8 +104114,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108304,8 +104130,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108322,8 +104147,7 @@ - s_3743: 0.56493352 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108339,8 +104163,7 @@ - s_3743: 0.84740028 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108356,8 +104179,7 @@ - s_3743: 0.84740028 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108373,8 +104195,7 @@ - s_3743: 0.84740028 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "SLIME reaction" + - subsystem: "SLIME reaction" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -108393,8 +104214,7 @@ - eccodes: - "4.4.1.17" - "4.4.1.-" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - bigg.reaction: "HEMELm" - kegg.reaction: "R02480" @@ -108416,8 +104236,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAL061W" - eccodes: "1.1.1.303" - - subsystem: - - "Butanoate metabolism" + - subsystem: "Butanoate metabolism" - annotation: !!omap - bigg.reaction: "ACTD" - kegg.reaction: "R02855" @@ -108439,8 +104258,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAL061W" - eccodes: "1.1.1.303" - - subsystem: - - "Butanoate metabolism" + - subsystem: "Butanoate metabolism" - annotation: !!omap - kegg.reaction: "R02855" - metanetx.reaction: "MNXR95419" @@ -108465,8 +104283,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL080C" - eccodes: "6.3.5.-" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 10000000 @@ -108484,8 +104301,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBL091C or YLR244C" - eccodes: "3.4.11.18" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 2.76 @@ -108505,8 +104321,7 @@ - eccodes: - "3.1.3.84" - "3.2.2.-" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 10.45 @@ -108525,8 +104340,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR046C" - eccodes: "1.6.5.5" - - subsystem: - - "Ubiquinone and other terpenoid-quinone biosynthesis" + - subsystem: "Ubiquinone and other terpenoid-quinone biosynthesis" - annotation: !!omap - kegg.reaction: "R02364" - metanetx.reaction: "MNXR107466" @@ -108547,8 +104361,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR070C and YGL047W" - eccodes: "2.4.1.141" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R05970" - metanetx.reaction: "MNXR100208" @@ -108569,8 +104382,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR111C" - eccodes: "3.6.1.13" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -31.39 @@ -108585,8 +104397,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR147W or YDR352W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 2.71 @@ -108601,8 +104412,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR147W or YDR352W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 1.74 @@ -108617,8 +104427,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR147W or YDR352W" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 2.71 @@ -108638,8 +104447,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR222C" - eccodes: "6.-.-.-" - - subsystem: - - "Glyoxylate and dicarboxylate metabolism" + - subsystem: "Glyoxylate and dicarboxylate metabolism" - annotation: !!omap - kegg.reaction: "R01558" - metanetx.reaction: "MNXR102232" @@ -108659,8 +104467,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR229C" - eccodes: "3.2.1.84" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R05980" - metanetx.reaction: "MNXR109971" @@ -108680,8 +104487,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR229C" - eccodes: "3.2.1.84" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R05981" - metanetx.reaction: "MNXR109972" @@ -108703,8 +104509,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR235W" - eccodes: "3.6.3.7" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -108719,8 +104524,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR241C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -2.32 @@ -108735,8 +104539,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR241C" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -2.32 @@ -108754,8 +104557,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR243C" - eccodes: "2.7.8.15" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R01007" - metanetx.reaction: "MNXR106786" @@ -108775,8 +104577,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR281C and YNL191W" - eccodes: "3.4.-.-" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "GTHRDH_syn" - kegg.reaction: "R03916" @@ -108800,35 +104601,13 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR295W" - eccodes: "3.6.3.3" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CD2abc1" - sbo: "SBO:0000655" - deltaG: 10000000 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4173" - - name: "L-cysteine:sulfur-acceptor sulfurtransferase" - - metabolites: !!omap - - s_0957: 1 - - s_3784: -1 - - s_3785: -1 - - s_3786: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YCL017C" - - eccodes: "2.8.1.7" - - subsystem: - - "Thiamine metabolism" - - annotation: !!omap - - kegg.reaction: "R11528" - - metanetx.reaction: "MNXR114822" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4174" - name: "Probable ATP-dependent permease" @@ -108838,8 +104617,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YCR011C" - - subsystem: - - "Transport [erm, er]" + - subsystem: "Transport [erm, er]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -108858,8 +104636,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR107W or YDL243C or YJR155W or YNL331C or YOL165C or YPL088W" - eccodes: "1.1.1.-" - - subsystem: - - "Methylglyoxal metabolism" + - subsystem: "Methylglyoxal metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 3.27 @@ -108878,8 +104655,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR107W or YDL243C or YJR155W or YNL331C or YOL165C or YPL088W" - eccodes: "1.1.1.-" - - subsystem: - - "Methylglyoxal metabolism" + - subsystem: "Methylglyoxal metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 3.26 @@ -108898,8 +104674,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR107W or YDL243C or YJR155W or YNL331C or YOL165C or YPL088W" - eccodes: "1.1.1.-" - - subsystem: - - "Methylglyoxal metabolism" + - subsystem: "Methylglyoxal metabolism" - annotation: !!omap - bigg.reaction: "3MBZALDH" - kegg.reaction: "R05347" @@ -108921,8 +104696,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR107W or YDL243C or YJR155W or YNL331C or YOL165C or YPL088W" - eccodes: "1.1.1.-" - - subsystem: - - "Methylglyoxal metabolism" + - subsystem: "Methylglyoxal metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 3.27 @@ -108941,8 +104715,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR107W or YDL243C or YJR155W or YNL331C or YOL165C or YPL088W" - eccodes: "1.1.1.-" - - subsystem: - - "Methylglyoxal metabolism" + - subsystem: "Methylglyoxal metabolism" - annotation: !!omap - bigg.reaction: "4MBZALDH" - sbo: "SBO:0000176" @@ -108962,8 +104735,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YCR107W or YDL243C or YJR155W or YNL331C or YOL165C or YPL088W" - eccodes: "1.1.1.-" - - subsystem: - - "Methylglyoxal metabolism" + - subsystem: "Methylglyoxal metabolism" - annotation: !!omap - bigg.reaction: "BZALDH" - kegg.reaction: "R01763" @@ -108987,8 +104759,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL031W" - eccodes: "3.6.3.-" - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -109007,8 +104778,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YEL070W or YNR073C" - eccodes: "1.1.1.-" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - bigg.reaction: "MNLDH2" - kegg.reaction: "R00868" @@ -109029,8 +104799,7 @@ - eccodes: - "4.1.3.17" - "4.1.1.3" - - subsystem: - - "C5-branched dibasic acid metabolism" + - subsystem: "C5-branched dibasic acid metabolism" - annotation: !!omap - kegg.reaction: "R00008" - metanetx.reaction: "MNXR106336" @@ -109052,8 +104821,7 @@ - eccodes: - "4.1.3.17" - "4.1.1.3" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "OAADC" - kegg.reaction: "R00217" @@ -109076,8 +104844,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER042W" - eccodes: "1.8.4.11" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - kegg.reaction: "R07606" - metanetx.reaction: "MNXR101484" @@ -109099,8 +104866,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER087W" - eccodes: "6.1.1.15" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - kegg.reaction: "R03661" - metanetx.reaction: "MNXR103208" @@ -109119,8 +104885,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER163C" - eccodes: "4.3.2.-" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "GGCLUT2" - kegg.reaction: "R11861" @@ -109139,8 +104904,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHL018W" - eccodes: "4.2.1.96" - - subsystem: - - "Folate biosynthesis" + - subsystem: "Folate biosynthesis" - annotation: !!omap - kegg.reaction: "R04734" - metanetx.reaction: "MNXR143540" @@ -109160,8 +104924,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR008C" - eccodes: "1.15.1.1" - - subsystem: - - "Superoxide metabolism" + - subsystem: "Superoxide metabolism" - annotation: !!omap - bigg.reaction: "SPODMm" - kegg.reaction: "R00275" @@ -109182,8 +104945,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR043C or YHR044C" - eccodes: "3.1.3.68" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - bigg.reaction: "2DOXG6PP" - kegg.reaction: "R02587" @@ -109205,8 +104967,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR109W" - eccodes: "2.1.1.59" - - subsystem: - - "Lysine metabolism" + - subsystem: "Lysine metabolism" - annotation: !!omap - kegg.reaction: "R03875" - metanetx.reaction: "MNXR108494" @@ -109214,28 +104975,6 @@ - deltaG: 10000000 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4193" - - name: "S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase" - - metabolites: !!omap - - s_0800: 1 - - s_3818: -1 - - s_3819: -1 - - s_3820: 1 - - s_3821: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YHR119W or YDR440W or YJL168C" - - eccodes: "2.1.1.43" - - subsystem: - - "Lysine metabolism" - - annotation: !!omap - - kegg.reaction: "R03938" - - metanetx.reaction: "MNXR108541" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4194" - name: "Zinc transporter YKE4" @@ -109245,8 +104984,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YIL023C" - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -109261,8 +104999,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YMR243C or YOR316C" - - subsystem: - - "Transport [m, v]" + - subsystem: "Transport [m, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -109281,8 +105018,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL043C or YML125C" - eccodes: "1.6.2.2" - - subsystem: - - "Amino sugar and nucleotide sugar metabolism" + - subsystem: "Amino sugar and nucleotide sugar metabolism" - annotation: !!omap - kegg.reaction: "R00100" - metanetx.reaction: "MNXR106388" @@ -109303,8 +105039,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL043C or YKL150W or YML125C" - eccodes: "1.6.2.2" - - subsystem: - - "Amino sugar and nucleotide sugar metabolism" + - subsystem: "Amino sugar and nucleotide sugar metabolism" - annotation: !!omap - bigg.reaction: "FCYTOB5OXR_m" - kegg.reaction: "R00100" @@ -109326,76 +105061,12 @@ - upper_bound: 1000 - gene_reaction_rule: "YIR036C" - eccodes: "1.1.1.320" - - subsystem: - - "Other" + - subsystem: "Other" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 9.76 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4199" - - name: "Glutathione S-transferase 1 (EC 2.5.1.18) (GST-I)" - - metabolites: !!omap - - s_3830: -1 - - s_3831: -1 - - s_3832: 1 - - s_3833: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YIR038C" - - eccodes: "2.5.1.18" - - subsystem: - - "Glutathione metabolism" - - annotation: !!omap - - kegg.reaction: "R03522" - - metanetx.reaction: "MNXR125877" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142) | MetaNetX ID curated (PR #220)" - - !!omap - - id: "r_4200" - - name: "Glutathione S-transferase 1 (EC 2.5.1.18) (GST-I)" - - metabolites: !!omap - - s_0750: -1 - - s_3834: -1 - - s_3835: 1 - - s_3836: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YMR251W or YKR076W" - - eccodes: "2.5.1.18" - - subsystem: - - "Glutathione metabolism" - - annotation: !!omap - - kegg.reaction: "R03522" - - metanetx.reaction: "MNXR125877" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142) | MetaNetX ID curated (PR #220)" - - !!omap - - id: "r_4201" - - name: "Glutathione S-transferase 1 (EC 2.5.1.18) (GST-I)" - - metabolites: !!omap - - s_0752: -1 - - s_4028: -1 - - s_4029: 1 - - s_4030: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YLL060C" - - eccodes: "2.5.1.18" - - subsystem: - - "Glutathione metabolism" - - annotation: !!omap - - kegg.reaction: "R03522" - - metanetx.reaction: "MNXR125877" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142) | MetaNetX ID curated (PR #220)" - !!omap - id: "r_4202" - name: "L-methionine:oxidized-thioredoxin S-oxidoreductase" @@ -109410,8 +105081,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL069W" - eccodes: "1.8.4.14" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "METSOXR1" - kegg.reaction: "R02025" @@ -109432,8 +105102,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL103C" - eccodes: "3.4.11.22" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 2.99 @@ -109451,8 +105120,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL103C" - eccodes: "3.4.11.22" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -1.2 @@ -109473,8 +105141,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL215C" - eccodes: "3.5.2.9" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "OPAH" - kegg.reaction: "R00251" @@ -109494,8 +105161,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YKL218C" - eccodes: "4.3.1.16" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - kegg.reaction: "R05758" - metanetx.reaction: "MNXR109814" @@ -109503,27 +105169,6 @@ - deltaG: -0.74 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4207" - - name: "Glutathione S-transferase omega-like 2 (EC 2.5.1.18) (Extracellular mutant protein 4) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1)" - - metabolites: !!omap - - s_3842: -1 - - s_3843: -1 - - s_3844: 1 - - s_3845: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YGR154C" - - eccodes: "2.5.1.18" - - subsystem: - - "Glutathione metabolism" - - annotation: !!omap - - kegg.reaction: "R03522" - - metanetx.reaction: "MNXR125877" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142) | MetaNetX ID curated (PR #220)" - !!omap - id: "r_4208" - name: "glutathione:dehydroascorbate oxidoreductase" @@ -109538,8 +105183,7 @@ - eccodes: - "2.5.1.18" - "1.8.5.1" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "GTHDH" - kegg.reaction: "R01108" @@ -109562,8 +105206,7 @@ - eccodes: - "2.5.1.18" - "1.8.5.1" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - kegg.reaction: "R01108" - metanetx.reaction: "MNXR138490" @@ -109582,8 +105225,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFL061W or YNL335W" - eccodes: "4.2.1.69" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - kegg.reaction: "R00778" - metanetx.reaction: "MNXR106683" @@ -109609,8 +105251,7 @@ - eccodes: - "4.3.3.6" - "3.5.1.2" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - kegg.reaction: "R10089" - metanetx.reaction: "MNXR140225" @@ -109636,8 +105277,7 @@ - eccodes: - "4.3.3.6" - "3.5.1.2" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "PYDXS" - kegg.reaction: "R07456" @@ -109658,8 +105298,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YFR044C" - eccodes: "3.4.13.-" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - bigg.reaction: "AMPTASECG" - kegg.reaction: "R00899" @@ -109668,27 +105307,6 @@ - deltaG: 4.56 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4215" - - name: "Cys-Gly metallodipeptidase DUG1 (EC 3.4.13.-) (Deficient in utilization of glutathione protein 1) (GSH degradosomal complex subunit DUG1)" - - metabolites: !!omap - - s_0803: -1 - - s_1003: 1 - - s_3853: -1 - - s_3854: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YFR044C" - - eccodes: "3.4.13.-" - - subsystem: - - "Glutathione metabolism" - - annotation: !!omap - - kegg.reaction: "R04951" - - metanetx.reaction: "MNXR109244" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4216" - name: "riboflavin-5-phosphate phosphohydrolase" @@ -109701,8 +105319,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL024C" - eccodes: "3.1.3.2" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - bigg.reaction: "ACP1_FMN" - kegg.reaction: "R00548" @@ -109724,8 +105341,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL120W" - eccodes: "1.16.3.1" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - kegg.reaction: "R00078" - metanetx.reaction: "MNXR99561" @@ -109748,8 +105364,7 @@ - eccodes: - "3.1.1.96" - "3.1.1.-" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 10000000 @@ -109770,8 +105385,7 @@ - eccodes: - "3.1.1.96" - "3.1.1.-" - - subsystem: - - "tRNA metabolism" + - subsystem: "tRNA metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 10000000 @@ -109790,8 +105404,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL236W" - eccodes: "3.1.3.41" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - kegg.reaction: "R03024" - metanetx.reaction: "MNXR107896" @@ -109812,8 +105425,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDL246C" - eccodes: "1.1.1.14" - - subsystem: - - "Pentose and glucuronate interconversions" + - subsystem: "Pentose and glucuronate interconversions" - annotation: !!omap - bigg.reaction: "RE1317C" - kegg.reaction: "R02896" @@ -109834,8 +105446,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR009W" - - subsystem: - - "Galactose metabolism" + - subsystem: "Galactose metabolism" - annotation: !!omap - bigg.reaction: "GALK2" - kegg.reaction: "R01092" @@ -109857,8 +105468,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR036C" - eccodes: "3.1.2.4" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - kegg.reaction: "R03352" - metanetx.reaction: "MNXR108112" @@ -109881,36 +105491,13 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR038C or YDR039C or YDR040C" - eccodes: "3.6.3.7" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "NAabcO" - sbo: "SBO:0000655" - deltaG: 10000000 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4225" - - name: "Broad-range acid phosphatase DET1 (EC 3.1.3.-) (Decreased ergosterol transport protein 1)" - - metabolites: !!omap - - s_0394: 1 - - s_0434: -1 - - s_0794: 1 - - s_0803: -1 - - s_1322: 1 - - s_3865: -1 - - s_3866: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YDR051C or YOL075C" - - eccodes: "3.1.3.-" - - subsystem: - - "Transport [c, e]" - - annotation: !!omap - - sbo: "SBO:0000655" - - deltaG: -2.69 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4226" - name: "L-Alanine:2-oxoglutarate aminotransferase" @@ -109923,8 +105510,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR111C" - eccodes: "2.6.1.2" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "ALATA_L" - kegg.reaction: "R00258" @@ -109945,8 +105531,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR242W" - eccodes: "3.5.1.4" - - subsystem: - - "Phenylalanine metabolism" + - subsystem: "Phenylalanine metabolism" - annotation: !!omap - bigg.reaction: "AMID2" - kegg.reaction: "R02540" @@ -109967,8 +105552,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR242W" - eccodes: "3.5.1.4" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "AMID3" - kegg.reaction: "R03096" @@ -109989,8 +105573,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR242W" - eccodes: "3.5.1.4" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - bigg.reaction: "AMID5" - kegg.reaction: "R05551" @@ -110011,8 +105594,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR242W" - eccodes: "3.5.1.4" - - subsystem: - - "Other" + - subsystem: "Other" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -5.11 @@ -110031,8 +105613,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR248C" - eccodes: "2.7.1.12" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "GNK" - kegg.reaction: "R01737" @@ -110041,27 +105622,6 @@ - deltaG: -16 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4233" - - name: "S-Adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase" - - metabolites: !!omap - - s_1413: 1 - - s_1416: -1 - - s_3876: -1 - - s_3877: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YDR410C" - - eccodes: "2.1.1.100" - - subsystem: - - "Terpenoid backbone biosynthesis" - - annotation: !!omap - - kegg.reaction: "R04496" - - metanetx.reaction: "MNXR108926" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4234" - name: "Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19 (GPI-GlcNAc transferase complex subunit GPI19) (GPI-GnT subunit GPI19) (EC 2.4.1.198)" @@ -110075,8 +105635,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR437W and YGR216C and YNL038W and YPL076W and YPL175W and YPL096C-A" - eccodes: "2.4.1.198" - - subsystem: - - "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" + - subsystem: "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" - annotation: !!omap - kegg.reaction: "R05916" - metanetx.reaction: "MNXR109940" @@ -110096,8 +105655,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR533C or YMR322C or YOR391C or YPL280W" - eccodes: "4.2.1.130" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - bigg.reaction: "GLYOX3" - kegg.reaction: "R09796" @@ -110121,8 +105679,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL006W" - eccodes: "3.6.3.8" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -110143,35 +105700,12 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL167C" - eccodes: "3.6.3.8" - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4239" - - name: "L-arginyl-tRNA(Arg):protein arginyltransferase" - - metabolites: !!omap - - s_0428: -1 - - s_0794: 1 - - s_1583: 1 - - s_3884: -1 - - s_3885: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YGL017W" - - eccodes: "2.3.2.8" - - subsystem: - - "tRNA metabolism" - - annotation: !!omap - - kegg.reaction: "R03862" - - metanetx.reaction: "MNXR108483" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4241" - name: "Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A-glucosidase I) (Glucosidase I)" @@ -110184,8 +105718,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL027C" - eccodes: "3.2.1.106" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R05979" - metanetx.reaction: "MNXR109970" @@ -110206,8 +105739,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL038C" - eccodes: "2.4.1.232" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R08599" - metanetx.reaction: "MNXR112120" @@ -110230,8 +105762,7 @@ - eccodes: - "2.4.1.132" - "2.4.1.257" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R05973" - metanetx.reaction: "MNXR109280" @@ -110254,8 +105785,7 @@ - eccodes: - "2.4.1.132" - "2.4.1.257" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R06238" - metanetx.reaction: "MNXR110084" @@ -110275,8 +105805,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL156W" - eccodes: "3.2.1.24" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - kegg.reaction: "R09645" - metanetx.reaction: "MNXR101397" @@ -110284,25 +105813,6 @@ - deltaG: -3.02 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142) | KEGG ID curated (PR #220)" - - !!omap - - id: "r_4246" - - name: "Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase)" - - metabolites: !!omap - - s_0810: -1 - - s_3900: -1 - - s_3901: 1 - - s_3902: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "YGL156W" - - eccodes: "3.2.1.24" - - subsystem: - - "Fructose and mannose metabolism" - - annotation: !!omap - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4247" - name: "ATP:L-threonyl,bicarbonate adenylyltransferase" @@ -110317,8 +105827,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL169W" - eccodes: "2.7.7.87" - - subsystem: - - "Threonylcarbamoyladenosine metabolism" + - subsystem: "Threonylcarbamoyladenosine metabolism" - annotation: !!omap - kegg.reaction: "R10463" - metanetx.reaction: "MNXR113802" @@ -110337,8 +105846,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL196W" - eccodes: "4.3.1.18" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "SERD_D" - kegg.reaction: "R00221" @@ -110359,8 +105867,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR012W" - eccodes: "2.5.1.47" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "CYSS_m" - kegg.reaction: "R00897" @@ -110382,8 +105889,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR036C" - eccodes: "3.6.1.43" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R01004" - metanetx.reaction: "MNXR106783" @@ -110391,50 +105897,6 @@ - deltaG: 10000000 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142) | model.S(602,3615) curated (PR #222)" - - !!omap - - id: "r_4251" - - name: "CTP:phosphatidate cytidyltransferase" - - metabolites: !!omap - - s_0541: -1 - - s_0636: 1 - - s_0799: -1 - - s_3907: -1 - - s_3908: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YGR046W" - - eccodes: "2.7.7.41" - - subsystem: - - "Glycerophospholipid metabolism" - - annotation: !!omap - - kegg.reaction: "R01799" - - metanetx.reaction: "MNXR107177" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142) | model.S(606,3616) curated (PR #222)" - - !!omap - - id: "r_4252" - - name: "Thiamine thiazole synthase (Thiazole biosynthetic enzyme)" - - metabolites: !!omap - - s_0803: 3 - - s_1003: -1 - - s_1198: -1 - - s_1216: 1 - - s_3909: -1 - - s_3910: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YGR144W" - - subsystem: - - "Thiamine metabolism" - - annotation: !!omap - - kegg.reaction: "R10685" - - metanetx.reaction: "MNXR139808" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142) | MetaNetX ID curated (PR #220)" - !!omap - id: "r_4253" - name: "dolichyl beta-D-glucosyl phosphate:D-Glc-alpha-(1->3)-D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-glucosyltransferase" @@ -110448,8 +105910,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR227W" - eccodes: "2.4.1.256" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R06264" - metanetx.reaction: "MNXR110098" @@ -110471,8 +105932,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR234W" - eccodes: "1.14.12.17" - - subsystem: - - "Nitrogen metabolism" + - subsystem: "Nitrogen metabolism" - annotation: !!omap - bigg.reaction: "NODOx" - kegg.reaction: "R05724" @@ -110495,8 +105955,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR234W" - eccodes: "1.14.12.17" - - subsystem: - - "Nitrogen metabolism" + - subsystem: "Nitrogen metabolism" - annotation: !!omap - bigg.reaction: "NODOy" - kegg.reaction: "R05725" @@ -110505,51 +105964,6 @@ - deltaG: 10000000 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4256" - - name: "Putative lipoate-protein ligase A (EC 6.3.1.20) (Altered inheritance rate of mitochondria protein 22)" - - metabolites: !!omap - - s_0434: -1 - - s_0633: 1 - - s_0794: -1 - - s_3915: -1 - - s_3916: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "YJL046W" - - eccodes: "6.3.1.20" - - subsystem: - - "Lipoic acid metabolism" - - annotation: !!omap - - kegg.reaction: "R07770" - - metanetx.reaction: "MNXR101081" - - sbo: "SBO:0000176" - - deltaG: -5.03 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4258" - - name: "[lipoyl-carrier protein]-L-lysine:lipoate ligase (AMP-forming)" - - metabolites: !!omap - - s_0423: 1 - - s_0434: -1 - - s_0633: 1 - - s_3915: -1 - - s_3917: -1 - - s_3918: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "YJL046W" - - eccodes: "6.3.1.20" - - subsystem: - - "Lipoic acid metabolism" - - annotation: !!omap - - kegg.reaction: "R11143" - - metanetx.reaction: "MNXR114442" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4260" - name: "Deaminated glutathione amidase (dGSH amidase) (EC 3.5.1.-) (Nitrilase homolog 1)" @@ -110562,8 +105976,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL126W" - eccodes: "3.5.1.-" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - kegg.reaction: "R12024" - sbo: "SBO:0000176" @@ -110582,8 +105995,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL126W" - eccodes: "3.5.1.-" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - kegg.reaction: "R12024" - sbo: "SBO:0000176" @@ -110600,8 +106012,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL200C" - eccodes: "4.2.1.-" - - subsystem: - - "Lysine metabolism" + - subsystem: "Lysine metabolism" - annotation: !!omap - bigg.reaction: "ACONTm" - kegg.reaction: "R01324" @@ -110619,8 +106030,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YJR040W" - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -0.19 @@ -110639,8 +106049,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR051W" - eccodes: "1.3.1.6" - - subsystem: - - "Cellular response to anaerobic conditions" + - subsystem: "Cellular response to anaerobic conditions" - annotation: !!omap - kegg.reaction: "R00402" - metanetx.reaction: "MNXR106516" @@ -110648,28 +106057,6 @@ - deltaG: 13.92 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142) | rxnDirection curated (PR #227)" - - !!omap - - id: "r_4265" - - name: "nucleoside-triphosphate diphosphohydrolase" - - metabolites: !!omap - - s_0633: 1 - - s_0794: 1 - - s_0803: -1 - - s_3927: -1 - - s_3928: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "YJR069C" - - eccodes: "3.6.1.9" - - subsystem: - - "Purine metabolism" - - annotation: !!omap - - kegg.reaction: "R01532" - - metanetx.reaction: "MNXR107043" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4266" - name: "Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.9) (Hydroxylaminopurine sensitivity protein 1) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase)" @@ -110683,8 +106070,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR069C" - eccodes: "3.6.1.9" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTPP5" - sbo: "SBO:0000176" @@ -110704,8 +106090,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR069C" - eccodes: "3.6.1.9" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTPP1" - kegg.reaction: "R01855" @@ -110727,8 +106112,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR069C" - eccodes: "3.6.1.9" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTPP7" - kegg.reaction: "R11323" @@ -110750,8 +106134,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR069C" - eccodes: "3.6.1.9" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 10000000 @@ -110769,8 +106152,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR104C" - eccodes: "1.15.1.1" - - subsystem: - - "Superoxide metabolism" + - subsystem: "Superoxide metabolism" - annotation: !!omap - bigg.reaction: "SPODM" - kegg.reaction: "R00275" @@ -110793,8 +106175,7 @@ - eccodes: - "3.2.1.113" - "3.2.1.-" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R05982" - metanetx.reaction: "MNXR109973" @@ -110816,8 +106197,7 @@ - eccodes: - "3.2.1.113" - "3.2.1.-" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R06722" - metanetx.reaction: "MNXR110483" @@ -110841,8 +106221,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJR149W" - eccodes: "1.13.12.16" - - subsystem: - - "Nitrogen metabolism" + - subsystem: "Nitrogen metabolism" - annotation: !!omap - kegg.reaction: "R00025" - metanetx.reaction: "MNXR106342" @@ -110864,8 +106243,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL058W or YML082W" - eccodes: "2.5.1.48" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "SHSL4r" - kegg.reaction: "R00999" @@ -110887,8 +106265,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR047C or YKL220C or YLR214W or YNR060W or YOL152W or YOR381W or YOR384W" - eccodes: "1.16.1.7" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - kegg.reaction: "R09541" - metanetx.reaction: "MNXR112960" @@ -110909,8 +106286,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLL051C" - eccodes: "1.16.1.7" - - subsystem: - - "Porphyrin and chlorophyll metabolism" + - subsystem: "Porphyrin and chlorophyll metabolism" - annotation: !!omap - kegg.reaction: "R09541" - metanetx.reaction: "MNXR112960" @@ -110918,51 +106294,6 @@ - deltaG: -56.75 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4277" - - name: "acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase" - - metabolites: !!omap - - s_0530: 1 - - s_3937: -1 - - s_3938: -1 - - s_3939: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YLR099C or YPR139C" - - eccodes: "2.3.1.51" - - subsystem: - - "Glycerolipid metabolism" - - annotation: !!omap - - kegg.reaction: "R00851" - - metanetx.reaction: "MNXR106715" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4278" - - name: "diphthine:ammonia ligase (AMP-forming)" - - metabolites: !!omap - - s_0419: -1 - - s_0423: 1 - - s_0434: -1 - - s_0633: 1 - - s_0794: 1 - - s_3940: -1 - - s_3941: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "YLR143W" - - eccodes: "6.3.1.14" - - subsystem: - - "Peptidyl-diphthamide biosynthetic process" - - annotation: !!omap - - kegg.reaction: "R03613" - - metanetx.reaction: "MNXR108295" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4279" - name: "8-oxo-dGTP diphosphohydrolase" @@ -110976,8 +106307,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR151C" - eccodes: "3.6.1.55" - - subsystem: - - "DNA repair" + - subsystem: "DNA repair" - annotation: !!omap - kegg.reaction: "R09832" - metanetx.reaction: "MNXR113234" @@ -110985,48 +106315,6 @@ - deltaG: -5.68 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142) | model.S(608,3642) curated (PR #222) | rxnDirection curated (PR #227)" - - !!omap - - id: "r_4280" - - name: "octanoyl-[acp]:protein N6-octanoyltransferase" - - metabolites: !!omap - - s_1254: -1 - - s_1845: 1 - - s_3944: -1 - - s_3945: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YLR239C" - - eccodes: "2.3.1.181" - - subsystem: - - "Lipoic acid metabolism" - - annotation: !!omap - - kegg.reaction: "R07766" - - metanetx.reaction: "MNXR111354" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4281" - - name: "lipoyl-[acp]:protein N6-lipoyltransferase" - - metabolites: !!omap - - s_1845: 1 - - s_3944: -1 - - s_3946: -1 - - s_3947: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YLR239C" - - eccodes: "2.3.1.181" - - subsystem: - - "Lipoic acid metabolism" - - annotation: !!omap - - kegg.reaction: "R07769" - - metanetx.reaction: "MNXR111357" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4282" - name: "ATP:D-fructose-6-phosphate 2-phosphotransferase" @@ -111042,8 +106330,7 @@ - eccodes: - "2.7.1.105" - "3.1.3.46" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - bigg.reaction: "PFK26_1" - kegg.reaction: "R02732" @@ -111065,8 +106352,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR446W" - eccodes: "2.7.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - kegg.reaction: "R00867" - metanetx.reaction: "MNXR100614" @@ -111087,8 +106373,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR446W" - eccodes: "2.7.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "GLUK_syn" - kegg.reaction: "R01600" @@ -111110,8 +106395,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR446W" - eccodes: "2.7.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "GLUKA" - kegg.reaction: "R01786" @@ -111133,8 +106417,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR446W" - eccodes: "2.7.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "HEX10" - kegg.reaction: "R01961" @@ -111156,8 +106439,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR446W" - eccodes: "2.7.1.1" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "ABFPT" - kegg.reaction: "R03920" @@ -111176,8 +106458,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR099C" - eccodes: "5.1.3.15" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - bigg.reaction: "G6PI_1" - kegg.reaction: "R02739" @@ -111200,8 +106481,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - bigg.reaction: "GLYALDDr" - kegg.reaction: "R01752" @@ -111224,8 +106504,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "4ABUTD" - kegg.reaction: "R01986" @@ -111248,8 +106527,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "ABUTD" - kegg.reaction: "R02549" @@ -111272,8 +106550,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - bigg.reaction: "ALDD20x" - kegg.reaction: "R02678" @@ -111296,8 +106573,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - kegg.reaction: "R02940" - metanetx.reaction: "MNXR107839" @@ -111319,8 +106595,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Ascorbate and aldarate metabolism" + - subsystem: "Ascorbate and aldarate metabolism" - annotation: !!omap - bigg.reaction: "ALDD32" - kegg.reaction: "R02957" @@ -111343,8 +106618,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Ascorbate and aldarate metabolism" + - subsystem: "Ascorbate and aldarate metabolism" - annotation: !!omap - kegg.reaction: "R03283" - metanetx.reaction: "MNXR108074" @@ -111366,8 +106640,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - kegg.reaction: "R03869" - metanetx.reaction: "MNXR95762" @@ -111389,8 +106662,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - kegg.reaction: "R04065" - metanetx.reaction: "MNXR95745" @@ -111412,8 +106684,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Sphingolipid metabolism" + - subsystem: "Sphingolipid metabolism" - annotation: !!omap - bigg.reaction: "r0688" - kegg.reaction: "R04506" @@ -111436,8 +106707,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - kegg.reaction: "R04903" - metanetx.reaction: "MNXR109205" @@ -111459,8 +106729,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "NABTNO" - kegg.reaction: "R05050" @@ -111483,8 +106752,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - kegg.reaction: "R05237" - metanetx.reaction: "MNXR109413" @@ -111506,8 +106774,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - kegg.reaction: "R05238" - metanetx.reaction: "MNXR109414" @@ -111529,8 +106796,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - kegg.reaction: "R05286" - metanetx.reaction: "MNXR109457" @@ -111552,8 +106818,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - kegg.reaction: "R06366" - metanetx.reaction: "MNXR110183" @@ -111575,8 +106840,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR110C" - eccodes: "1.2.1.3" - - subsystem: - - "Insect hormone biosynthesis" + - subsystem: "Insect hormone biosynthesis" - annotation: !!omap - kegg.reaction: "R08146" - metanetx.reaction: "MNXR111724" @@ -111584,28 +106848,6 @@ - deltaG: -10.61 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142) | model.S(601,3668) curated (PR #222)" - - !!omap - - id: "r_4308" - - name: "Probable phospholipid-transporting ATPase DNF3 (EC 3.6.3.1) (Aminophospholipid translocase) (APT) (Phospholipid translocase) (PLT)" - - metabolites: !!omap - - s_2783: 1 - - s_2808: -1 - - s_2831: -1 - - s_2966: 1 - - s_3985: -1 - - s_3986: 1 - - s_3987: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "YMR162C" - - eccodes: "3.6.3.1" - - subsystem: - - "Transport [erm, gm]" - - annotation: !!omap - - sbo: "SBO:0000655" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4309" - name: "Putative esterase YMR210W (EC 3.1.1.-)" @@ -111619,8 +106861,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR210W" - eccodes: "3.1.1.-" - - subsystem: - - "Glycerophospholipid metabolism" + - subsystem: "Glycerophospholipid metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -2.55 @@ -111639,8 +106880,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL048W" - eccodes: "2.4.1.131" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R06127" - metanetx.reaction: "MNXR110030" @@ -111661,8 +106901,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL048W" - eccodes: "2.4.1.131" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R06128" - metanetx.reaction: "MNXR110031" @@ -111683,8 +106922,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL092W" - eccodes: "2.1.1.22" - - subsystem: - - "Histidine metabolism" + - subsystem: "Histidine metabolism" - annotation: !!omap - kegg.reaction: "R02144" - metanetx.reaction: "MNXR107333" @@ -111706,8 +106944,7 @@ - eccodes: - "2.4.1.259" - "2.4.1.261" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R06259" - metanetx.reaction: "MNXR110093" @@ -111729,8 +106966,7 @@ - eccodes: - "2.4.1.259" - "2.4.1.261" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R06261" - metanetx.reaction: "MNXR110095" @@ -111751,8 +106987,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNL274C" - eccodes: "1.1.1.26" - - subsystem: - - "Glyoxylate and dicarboxylate metabolism" + - subsystem: "Glyoxylate and dicarboxylate metabolism" - annotation: !!omap - bigg.reaction: "GLYCLTDx" - kegg.reaction: "R00717" @@ -111773,8 +107008,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YNR030W" - eccodes: "2.4.1.260" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R06260" - metanetx.reaction: "MNXR110094" @@ -111794,8 +107028,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL157C" - eccodes: "3.2.1.10" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "SUCR" - kegg.reaction: "R00801" @@ -111816,8 +107049,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL157C" - eccodes: "3.2.1.10" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - kegg.reaction: "R01718" - metanetx.reaction: "MNXR107140" @@ -111836,8 +107068,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL157C" - eccodes: "3.2.1.10" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - kegg.reaction: "R01791" - metanetx.reaction: "MNXR107171" @@ -111858,8 +107089,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR002W" - eccodes: "2.4.1.267" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R06262" - metanetx.reaction: "MNXR110096" @@ -111880,8 +107110,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR067C" - eccodes: "2.4.1.265" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R06263" - metanetx.reaction: "MNXR110097" @@ -111895,15 +107124,13 @@ - metabolites: !!omap - s_0644: -1 - s_0646: 1 - - s_0795: 1 - s_4002: -1 - s_4003: 1 - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YOR149C" - eccodes: "2.4.1.-" - - subsystem: - - "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" + - subsystem: "Glycosylphosphatidylinositol (gpi)-anchor biosynthesis" - annotation: !!omap - kegg.reaction: "R07129" - metanetx.reaction: "MNXR110833" @@ -111911,69 +107138,6 @@ - deltaG: 10000000 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4323" - - name: "protein N6-(octanoyl)lysine:sulfur sulfurtransferase" - - metabolites: !!omap - - s_1031: 2 - - s_1419: -2 - - s_3945: -1 - - s_3947: 1 - - s_4004: -2 - - s_4005: 2 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YOR196C" - - eccodes: "2.8.1.8" - - subsystem: - - "Lipoic acid metabolism" - - annotation: !!omap - - kegg.reaction: "R07767" - - metanetx.reaction: "MNXR111355" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4324" - - name: "octanoyl-[acp]:sulfur sulfurtransferase" - - metabolites: !!omap - - s_1031: 2 - - s_1254: -1 - - s_1419: -2 - - s_3946: 1 - - s_4004: -2 - - s_4005: 2 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YOR196C" - - eccodes: "2.8.1.8" - - subsystem: - - "Lipoic acid metabolism" - - annotation: !!omap - - kegg.reaction: "R07768" - - metanetx.reaction: "MNXR111356" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4325" - - name: "Iron sulfur cluster assembly protein 2, mitochondrial (Iron sulfur cluster scaffold protein 2)" - - metabolites: !!omap - - s_4006: -1 - - s_4007: -1 - - s_4008: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "YOR226C or YPL135W" - - subsystem: - - "Cysteine and methionine metabolism" - - annotation: !!omap - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4326" - name: "thiosulfate:cyanide sulfurtranserase" @@ -111989,8 +107153,7 @@ - eccodes: - "2.8.1.1" - "2.8.1.-" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - bigg.reaction: "CYANSTm" - kegg.reaction: "R01931" @@ -112008,8 +107171,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YOR334W or YPL060W" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -112028,8 +107190,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPL227C" - eccodes: "2.4.1.117" - - subsystem: - - "N-glycan biosynthesis" + - subsystem: "N-glycan biosynthesis" - annotation: !!omap - kegg.reaction: "R01005" - metanetx.reaction: "MNXR143462" @@ -112046,8 +107207,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YPR003C" - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - bigg.reaction: "HMR_9626" - sbo: "SBO:0000655" @@ -112067,8 +107227,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR127W" - eccodes: "1.1.1.65" - - subsystem: - - "Vitamin b6 metabolism" + - subsystem: "Vitamin b6 metabolism" - annotation: !!omap - bigg.reaction: "PYDXOR" - kegg.reaction: "R01708" @@ -112088,8 +107247,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR371W or YLR286C" - eccodes: "3.2.1.14" - - subsystem: - - "Amino sugar and nucleotide sugar metabolism" + - subsystem: "Amino sugar and nucleotide sugar metabolism" - annotation: !!omap - kegg.reaction: "R01206" - metanetx.reaction: "MNXR106866" @@ -112106,8 +107264,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YOR161C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CHOLtu" - sbo: "SBO:0000655" @@ -112129,8 +107286,7 @@ - "3.6.1.10" - "3.6.1.-" - "3.6.1.11" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - kegg.reaction: "R03042" - metanetx.reaction: "MNXR107906" @@ -112153,8 +107309,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YDR270W" - eccodes: "3.6.3.54" - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -112176,8 +107331,7 @@ - "3.6.1.10" - "3.6.1.-" - "3.6.1.11" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "NTP2" - sbo: "SBO:0000176" @@ -112196,8 +107350,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR351C" - eccodes: "3.5.1.3" - - subsystem: - - "Alanine, aspartate and glutamate metabolism" + - subsystem: "Alanine, aspartate and glutamate metabolism" - annotation: !!omap - bigg.reaction: "r0085" - kegg.reaction: "R03804" @@ -112220,8 +107373,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YMR301C" - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -112238,8 +107390,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOL157C" - eccodes: "3.2.1.10" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - kegg.reaction: "R06199" - metanetx.reaction: "MNXR110064" @@ -112256,35 +107407,12 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YEL004W" - - subsystem: - - "Transport [er, g]" + - subsystem: "Transport [er, g]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 - confidence_score: 2 - rxnNotes: "added after new annotation (PR #142)" - - !!omap - - id: "r_4340" - - name: "D-amino-acid N-acetyltransferase HPA3 (DNT) (EC 2.3.1.36) (EC 2.3.1.48) (Histone and other protein acetyltransferase 3)" - - metabolites: !!omap - - s_0373: -1 - - s_0529: 1 - - s_0794: 1 - - s_4032: -1 - - s_4033: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YEL066W" - - eccodes: - - "2.3.1.36" - - "2.3.1.48" - - subsystem: - - "Phenylalanine metabolism" - - annotation: !!omap - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 2 - - rxnNotes: "added after new annotation (PR #142)" - !!omap - id: "r_4341" - name: "glycerol 2-phosphate(2-) transport" @@ -112293,8 +107421,7 @@ - s_4063: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR100319" - sbo: "SBO:0000655" @@ -112312,8 +107439,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.19" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - bigg.reaction: "G2PP" - kegg.reaction: "R01043" @@ -112330,10 +107456,9 @@ - s_0796: -1 - s_4064: 1 - s_4065: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR136678" - sbo: "SBO:0000655" @@ -112351,8 +107476,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.-" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - metanetx.reaction: "MNXR103332" - sbo: "SBO:0000176" @@ -112370,8 +107494,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.-" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - metanetx.reaction: "MNXR118732" - sbo: "SBO:0000176" @@ -112386,10 +107509,9 @@ - s_0796: -1 - s_4066: 1 - s_4067: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 1.28 @@ -112406,8 +107528,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.6" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "3NUCLE4" - kegg.reaction: "R02148" @@ -112424,10 +107545,9 @@ - s_0796: -1 - s_4068: 1 - s_4069: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "3GMPt6" - sbo: "SBO:0000655" @@ -112442,10 +107562,9 @@ - s_0796: -1 - s_4070: -1 - s_4071: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "2PGLYCt6" - metanetx.reaction: "MNXR94822" @@ -112464,8 +107583,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.18" - - subsystem: - - "Glyoxylate and dicarboxylate metabolism" + - subsystem: "Glyoxylate and dicarboxylate metabolism" - annotation: !!omap - bigg.reaction: "PGLYCP" - kegg.reaction: "R01334" @@ -112485,8 +107603,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.-" - - subsystem: - - "Taurine and hypotaurine metabolism" + - subsystem: "Taurine and hypotaurine metabolism" - annotation: !!omap - metanetx.reaction: "MNXR118734" - sbo: "SBO:0000176" @@ -112501,8 +107618,7 @@ - s_4075: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 1.46 @@ -112519,8 +107635,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "1.13.11.19" - - subsystem: - - "Taurine and hypotaurine metabolism" + - subsystem: "Taurine and hypotaurine metabolism" - annotation: !!omap - kegg.reaction: "R02467" - metanetx.reaction: "MNXR107528" @@ -112541,8 +107656,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "1.8.1.3" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - kegg.reaction: "R01681" - metanetx.reaction: "MNXR107116" @@ -112561,8 +107675,7 @@ - lower_bound: -1000 - upper_bound: 1000 - eccodes: "2.6.1.42" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "RE2034C" - kegg.reaction: "R10991" @@ -112579,10 +107692,9 @@ - s_0796: -1 - s_4079: 1 - s_4080: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -2.37 @@ -112599,8 +107711,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.-" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - metanetx.reaction: "MNXR118730" - sbo: "SBO:0000176" @@ -112615,10 +107726,9 @@ - s_0796: -1 - s_4081: 1 - s_4082: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR136675" - sbo: "SBO:0000655" @@ -112636,8 +107746,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.6" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - bigg.reaction: "3NUCLE2" - kegg.reaction: "R01877" @@ -112654,10 +107763,9 @@ - s_0796: -1 - s_4083: 1 - s_4084: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "3UMPt6" - metanetx.reaction: "MNXR94982" @@ -112673,11 +107781,10 @@ - s_0796: -1 - s_4085: -1 - s_4086: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137072" - sbo: "SBO:0000655" @@ -112695,8 +107802,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.4.13.18" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - metanetx.reaction: "MNXR123343" - sbo: "SBO:0000176" @@ -112712,8 +107818,7 @@ - s_4089: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - kegg.reaction: "R07420" - metanetx.reaction: "MNXR111061" @@ -112729,10 +107834,9 @@ - s_0796: -1 - s_4088: 1 - s_4090: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 10000000 @@ -112746,10 +107850,9 @@ - s_0796: -1 - s_4089: 1 - s_4091: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -2.76 @@ -112767,8 +107870,7 @@ - lower_bound: -1000 - upper_bound: 1000 - eccodes: "2.7.3.3" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - bigg.reaction: "ARGKr" - kegg.reaction: "R00554" @@ -112785,10 +107887,9 @@ - s_0796: -1 - s_4092: 1 - s_4093: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ARGPt6" - metanetx.reaction: "MNXR95947" @@ -112806,8 +107907,7 @@ - s_4096: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Tyrosine metabolism" + - subsystem: "Tyrosine metabolism" - annotation: !!omap - metanetx.reaction: "MNXR104998" - sbo: "SBO:0000176" @@ -112822,10 +107922,9 @@ - s_0796: -1 - s_4098: 1 - s_4099: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR135003" - sbo: "SBO:0000655" @@ -112843,8 +107942,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.-" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - metanetx.reaction: "MNXR118731" - sbo: "SBO:0000176" @@ -112859,10 +107957,9 @@ - s_0796: -1 - s_4100: 1 - s_4101: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR135010" - sbo: "SBO:0000655" @@ -112881,8 +107978,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR247W" - eccodes: "3.1.4.37" - - subsystem: - - "Cyclic nucleotide metabolism" + - subsystem: "Cyclic nucleotide metabolism" - annotation: !!omap - metanetx.reaction: "MNXR117327" - sbo: "SBO:0000176" @@ -112897,10 +107993,9 @@ - s_0796: -1 - s_4102: 1 - s_4103: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR136674" - sbo: "SBO:0000655" @@ -112919,8 +108014,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.13.1.-" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - kegg.reaction: "R00863" - metanetx.reaction: "MNXR123155" @@ -112936,10 +108030,9 @@ - s_0796: -1 - s_4104: 1 - s_4105: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137086" - sbo: "SBO:0000655" @@ -112957,8 +108050,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.6" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - bigg.reaction: "3NUCLE1" - kegg.reaction: "R01562" @@ -112975,8 +108067,7 @@ - s_4107: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR94857" - sbo: "SBO:0000655" @@ -112994,8 +108085,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.2.1.20" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - metanetx.reaction: "MNXR130717" - sbo: "SBO:0000176" @@ -113010,10 +108100,9 @@ - s_0796: -1 - s_4108: 1 - s_4109: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PALAt2" - metanetx.reaction: "MNXR102339" @@ -113032,8 +108121,7 @@ - s_4110: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - metanetx.reaction: "MNXR103637" - sbo: "SBO:0000176" @@ -113048,10 +108136,9 @@ - s_0796: -1 - s_4110: 1 - s_4111: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137052" - sbo: "SBO:0000655" @@ -113069,8 +108156,7 @@ - lower_bound: -1000 - upper_bound: 1000 - eccodes: "1.8.2.2" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - kegg.reaction: "R00029" - metanetx.reaction: "MNXR138952" @@ -113086,8 +108172,7 @@ - s_4114: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR104796" - sbo: "SBO:0000655" @@ -113108,8 +108193,7 @@ - eccodes: - "1.1.1.-" - "1.1.1.69" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - bigg.reaction: "5DGLCNR" - kegg.reaction: "R01740" @@ -113126,10 +108210,9 @@ - s_0796: -1 - s_4117: 1 - s_4118: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR95066" - sbo: "SBO:0000655" @@ -113147,8 +108230,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.4.13.18" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - metanetx.reaction: "MNXR123344" - sbo: "SBO:0000176" @@ -113163,11 +108245,10 @@ - s_0796: -1 - s_4119: -1 - s_4120: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137135" - sbo: "SBO:0000655" @@ -113186,8 +108267,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR247W" - eccodes: "3.1.4.37" - - subsystem: - - "Cyclic nucleotide metabolism" + - subsystem: "Cyclic nucleotide metabolism" - annotation: !!omap - metanetx.reaction: "MNXR117326" - sbo: "SBO:0000176" @@ -113202,10 +108282,9 @@ - s_0796: -1 - s_4126: 1 - s_4127: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR136673" - sbo: "SBO:0000655" @@ -113223,8 +108302,7 @@ - lower_bound: -1000 - upper_bound: 1000 - eccodes: "3.2.1.21" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - metanetx.reaction: "MNXR142673" - sbo: "SBO:0000176" @@ -113239,8 +108317,7 @@ - s_4124: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "MEOHt2" - metanetx.reaction: "MNXR101464" @@ -113256,10 +108333,9 @@ - s_0796: -1 - s_4122: 1 - s_4125: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR144815" - sbo: "SBO:0000655" @@ -113278,8 +108354,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "2.7.1.101" - - subsystem: - - "Galactose metabolism" + - subsystem: "Galactose metabolism" - annotation: !!omap - kegg.reaction: "R02927" - metanetx.reaction: "MNXR107830" @@ -113295,8 +108370,7 @@ - s_4129: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Galactose metabolism" + - subsystem: "Galactose metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 0 @@ -113311,8 +108385,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDL245C or YDR342C or YDR343C or YDR345C or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YMR011W or YNR072W or YOL156W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "TAGAT_Dt" - metanetx.reaction: "MNXR104707" @@ -113333,8 +108406,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "6.2.1.16" - - subsystem: - - "Butanoate metabolism" + - subsystem: "Butanoate metabolism" - annotation: !!omap - bigg.reaction: "AACOAT" - kegg.reaction: "R01357" @@ -113354,8 +108426,7 @@ - lower_bound: -1000 - upper_bound: 1000 - eccodes: "3.5.1.14" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "RE2640C" - metanetx.reaction: "MNXR103709" @@ -113371,11 +108442,10 @@ - s_0796: -1 - s_4034: -1 - s_4035: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137087" - sbo: "SBO:0000655" @@ -113392,8 +108462,7 @@ - s_4039: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR101006" - sbo: "SBO:0000655" @@ -113412,8 +108481,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR299W or YGR292W" - eccodes: "3.2.1.20" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - bigg.reaction: "MLTG1e" - kegg.reaction: "R05196" @@ -113432,8 +108500,7 @@ - s_4042: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -0.06 @@ -113447,11 +108514,10 @@ - s_0796: -1 - s_4040: -1 - s_4041: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -4.49 @@ -113469,8 +108535,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR201C or YDR452W" - eccodes: "3.6.1.25" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - kegg.reaction: "R00138" - metanetx.reaction: "MNXR103069" @@ -113486,11 +108551,10 @@ - s_0796: -1 - s_4053: -1 - s_4054: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -5.08 @@ -113504,8 +108568,7 @@ - s_4049: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 5.4 @@ -113519,10 +108582,9 @@ - s_0796: -1 - s_4077: 1 - s_4078: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PSER_Dt6" - metanetx.reaction: "MNXR103244" @@ -113541,8 +108603,7 @@ - lower_bound: -1000 - upper_bound: 1000 - eccodes: "3.1.3.3" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - bigg.reaction: "PSP_D" - kegg.reaction: "R02853" @@ -113559,11 +108620,10 @@ - s_0796: -1 - s_4037: -1 - s_4038: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR101006" - sbo: "SBO:0000655" @@ -113581,8 +108641,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.4.13.18" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - metanetx.reaction: "MNXR101011" - sbo: "SBO:0000176" @@ -113599,8 +108658,7 @@ - lower_bound: -1000 - upper_bound: 1000 - eccodes: "4.1.3.13" - - subsystem: - - "Glyoxylate and dicarboxylate metabolism" + - subsystem: "Glyoxylate and dicarboxylate metabolism" - annotation: !!omap - kegg.reaction: "R00477" - metanetx.reaction: "MNXR106549" @@ -113621,8 +108679,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "4.4.1.25" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - kegg.reaction: "R07634" - metanetx.reaction: "MNXR111236" @@ -113642,8 +108699,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR247W" - eccodes: "3.1.4.37" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - metanetx.reaction: "MNXR117325" - sbo: "SBO:0000176" @@ -113661,8 +108717,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.34" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - metanetx.reaction: "MNXR118741" - sbo: "SBO:0000176" @@ -113680,8 +108735,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.4.13.18" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - metanetx.reaction: "MNXR123345" - sbo: "SBO:0000176" @@ -113699,8 +108753,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.4.13.18" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - metanetx.reaction: "MNXR123347" - sbo: "SBO:0000176" @@ -113718,8 +108771,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.4.13.18" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - metanetx.reaction: "MNXR123349" - sbo: "SBO:0000176" @@ -113737,8 +108789,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.4.13.18" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - metanetx.reaction: "MNXR123350" - sbo: "SBO:0000176" @@ -113756,8 +108807,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.4.13.18" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - metanetx.reaction: "MNXR123351" - sbo: "SBO:0000176" @@ -113772,10 +108822,9 @@ - s_0796: -1 - s_4138: 1 - s_4139: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR124424" - sbo: "SBO:0000655" @@ -113794,8 +108843,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR299W or YGR292W" - eccodes: "3.2.1.20" - - subsystem: - - "Starch and sucrose metabolism" + - subsystem: "Starch and sucrose metabolism" - annotation: !!omap - metanetx.reaction: "MNXR130716" - sbo: "SBO:0000176" @@ -113810,10 +108858,9 @@ - s_0796: -1 - s_4115: 1 - s_4116: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137058" - sbo: "SBO:0000655" @@ -113828,10 +108875,9 @@ - s_0796: -1 - s_4136: 1 - s_4137: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137067" - sbo: "SBO:0000655" @@ -113848,8 +108894,7 @@ - s_4087: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR137072" - sbo: "SBO:0000655" @@ -113864,11 +108909,10 @@ - s_0796: -1 - s_4056: -1 - s_4057: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137074" - sbo: "SBO:0000655" @@ -113885,8 +108929,7 @@ - s_4058: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR137074" - sbo: "SBO:0000655" @@ -113903,8 +108946,7 @@ - s_4036: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR137087" - sbo: "SBO:0000655" @@ -113919,10 +108961,9 @@ - s_0796: -1 - s_4134: 1 - s_4135: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137089" - sbo: "SBO:0000655" @@ -113937,10 +108978,9 @@ - s_0796: -1 - s_4096: 1 - s_4097: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137095" - sbo: "SBO:0000655" @@ -113955,11 +108995,10 @@ - s_0796: -1 - s_4050: -1 - s_4051: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137107" - sbo: "SBO:0000655" @@ -113976,8 +109015,7 @@ - s_4052: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR137107" - sbo: "SBO:0000655" @@ -113994,8 +109032,7 @@ - s_4121: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR137135" - sbo: "SBO:0000655" @@ -114017,8 +109054,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "1.14.14.5" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - bigg.reaction: "FDMO" - metanetx.reaction: "MNXR99485" @@ -114034,8 +109070,7 @@ - s_4045: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.06 @@ -114049,8 +109084,7 @@ - s_4047: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 6.23 @@ -114067,8 +109101,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YIL053W or YER062C" - - subsystem: - - "Glycerolipid metabolism" + - subsystem: "Glycerolipid metabolism" - annotation: !!omap - kegg.reaction: "R08658" - metanetx.reaction: "MNXR112173" @@ -114086,8 +109119,7 @@ - s_4046: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 7.11 @@ -114101,11 +109133,10 @@ - s_0796: -1 - s_4059: -1 - s_4060: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -4.22 @@ -114121,8 +109152,7 @@ - s_4061: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 1.1 @@ -114139,8 +109169,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.4.13.18" - - subsystem: - - "Dipeptidases" + - subsystem: "Dipeptidases" - annotation: !!omap - metanetx.reaction: "MNXR123352" - sbo: "SBO:0000176" @@ -114155,8 +109184,7 @@ - s_3758: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -2.13 @@ -114170,8 +109198,7 @@ - s_4043: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -1.74 @@ -114184,8 +109211,7 @@ - s_4074: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_cysam_e" - sbo: "SBO:0000627" @@ -114199,8 +109225,7 @@ - s_4095: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR94721" - sbo: "SBO:0000655" @@ -114215,10 +109240,9 @@ - s_0794: 1 - s_0796: -1 - s_4141: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "2PGt6" - metanetx.reaction: "MNXR94824" @@ -114234,10 +109258,9 @@ - s_0794: 1 - s_0796: -1 - s_4142: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "3PGt6" - metanetx.reaction: "MNXR94973" @@ -114253,8 +109276,7 @@ - s_4145: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR99849" - sbo: "SBO:0000655" @@ -114269,8 +109291,7 @@ - s_4146: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR96488" - sbo: "SBO:0000655" @@ -114285,11 +109306,10 @@ - s_0796: -1 - s_4143: -1 - s_4144: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -4.09 @@ -114305,8 +109325,7 @@ - s_4144: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -0.45 @@ -114320,10 +109339,9 @@ - s_0794: 1 - s_0796: -1 - s_4147: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PSER_Lt6" - metanetx.reaction: "MNXR103245" @@ -114339,10 +109357,9 @@ - s_0794: 1 - s_0796: -1 - s_4148: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GMPt6" - metanetx.reaction: "MNXR100385" @@ -114358,8 +109375,7 @@ - s_4149: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR101585" - sbo: "SBO:0000655" @@ -114374,8 +109390,7 @@ - s_4150: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR99915" - sbo: "SBO:0000655" @@ -114390,8 +109405,7 @@ - s_4151: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR105127" - sbo: "SBO:0000655" @@ -114406,10 +109420,9 @@ - s_0796: -1 - s_1360: 1 - s_4152: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "PEPt6" - metanetx.reaction: "MNXR102493" @@ -114425,8 +109438,7 @@ - s_4153: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR101385" - sbo: "SBO:0000655" @@ -114441,11 +109453,10 @@ - s_0796: -1 - s_1239: 1 - s_4154: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YDR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR135002" - sbo: "SBO:0000655" @@ -114460,10 +109471,9 @@ - s_0794: 1 - s_0796: -1 - s_4155: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "6PGCt6" - metanetx.reaction: "MNXR95102" @@ -114479,10 +109489,9 @@ - s_0794: 1 - s_0796: -1 - s_4156: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "MAN1Pt6" - metanetx.reaction: "MNXR101377" @@ -114498,10 +109507,9 @@ - s_0794: 2 - s_0796: -2 - s_4157: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR136667" - sbo: "SBO:0000655" @@ -114516,8 +109524,7 @@ - s_4158: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CHOLPtr" - metanetx.reaction: "MNXR96703" @@ -114533,8 +109540,7 @@ - s_4159: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "TSULt" - metanetx.reaction: "MNXR104966" @@ -114550,10 +109556,9 @@ - s_0794: 1 - s_0796: -1 - s_4160: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "AMPt6" - metanetx.reaction: "MNXR95831" @@ -114569,8 +109574,7 @@ - s_4161: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR94718" - sbo: "SBO:0000655" @@ -114585,10 +109589,9 @@ - s_0794: 1 - s_0796: -1 - s_4162: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR135007" - sbo: "SBO:0000655" @@ -114603,10 +109606,9 @@ - s_0794: 1 - s_0796: -1 - s_4163: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CMPt6" - metanetx.reaction: "MNXR96805" @@ -114622,8 +109624,7 @@ - s_4164: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "GAMt1r" - metanetx.reaction: "MNXR100035" @@ -114640,8 +109641,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YDR342C or YHR092C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "DRIBt" - sbo: "SBO:0000655" @@ -114656,11 +109656,10 @@ - s_0796: -1 - s_0979: 1 - s_4166: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YKR039W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "CITRt2r" - metanetx.reaction: "MNXR96737" @@ -114676,8 +109675,7 @@ - s_4167: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "DHAt" - metanetx.reaction: "MNXR97367" @@ -114693,11 +109691,10 @@ - s_0796: -1 - s_4168: -1 - s_4169: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -3.69 @@ -114713,8 +109710,7 @@ - s_4169: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: -0.84 @@ -114728,11 +109724,10 @@ - s_0796: -1 - s_4170: -1 - s_4171: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YJR152W or YKR093W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137133" - sbo: "SBO:0000655" @@ -114749,8 +109744,7 @@ - s_4171: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR137133" - sbo: "SBO:0000655" @@ -114765,8 +109759,7 @@ - s_4173: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "ACGLUtd" - sbo: "SBO:0000655" @@ -114781,8 +109774,7 @@ - s_4173: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ACGLUtm" - sbo: "SBO:0000655" @@ -114797,10 +109789,9 @@ - s_0796: -1 - s_4174: -1 - s_4175: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "LPAMt" - metanetx.reaction: "MNXR137094" @@ -114816,8 +109807,7 @@ - s_4176: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR101483" - sbo: "SBO:0000655" @@ -114834,8 +109824,7 @@ - s_4055: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0.52 @@ -114849,10 +109838,9 @@ - s_0796: -1 - s_4073: 1 - s_4074: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR137130" - sbo: "SBO:0000655" @@ -114869,8 +109857,7 @@ - s_1467: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: 10000000 @@ -114886,8 +109873,7 @@ - s_3759: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR95704" - sbo: "SBO:0000655" @@ -114904,8 +109890,7 @@ - s_3839: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR100368" - sbo: "SBO:0000655" @@ -114926,8 +109911,7 @@ - eccodes: - "2.5.1.-" - "2.5.1.48" - - subsystem: - - "Cysteine and methionine metabolism" + - subsystem: "Cysteine and methionine metabolism" - annotation: !!omap - bigg.reaction: "SHSL2" - kegg.reaction: "R01288" @@ -114947,8 +109931,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "1.13.11.27" - - subsystem: - - "Tyrosine metabolism" + - subsystem: "Tyrosine metabolism" - annotation: !!omap - bigg.reaction: "34HPPOR" - kegg.reaction: "R02521" @@ -114968,8 +109951,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "1.13.11.5" - - subsystem: - - "Tyrosine metabolism" + - subsystem: "Tyrosine metabolism" - annotation: !!omap - bigg.reaction: "HGNTOR" - kegg.reaction: "R02519" @@ -114987,8 +109969,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "5.2.1.2" - - subsystem: - - "Tyrosine metabolism" + - subsystem: "Tyrosine metabolism" - annotation: !!omap - bigg.reaction: "MACACI" - kegg.reaction: "R03181" @@ -115009,8 +109990,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.7.1.2" - - subsystem: - - "Tyrosine metabolism" + - subsystem: "Tyrosine metabolism" - annotation: !!omap - bigg.reaction: "FUMAC" - kegg.reaction: "R01364" @@ -115031,8 +110011,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "1.1.1.12" - - subsystem: - - "Pentose and glucuronate interconversions" + - subsystem: "Pentose and glucuronate interconversions" - annotation: !!omap - bigg.reaction: "ABTD" - kegg.reaction: "R01903" @@ -115053,8 +110032,7 @@ - lower_bound: -1000 - upper_bound: 1000 - eccodes: "1.1.1.10" - - subsystem: - - "Pentose and glucuronate interconversions" + - subsystem: "Pentose and glucuronate interconversions" - annotation: !!omap - bigg.reaction: "XYLUR" - kegg.reaction: "R01904" @@ -115074,8 +110052,7 @@ - s_4181: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - sbo: "SBO:0000176" - deltaG: -9.79 @@ -115093,8 +110070,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "1.1.1.11" - - subsystem: - - "Pentose and glucuronate interconversions" + - subsystem: "Pentose and glucuronate interconversions" - annotation: !!omap - bigg.reaction: "ABTDG" - kegg.reaction: "R05604" @@ -115112,8 +110088,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNL065W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR95208" - sbo: "SBO:0000655" @@ -115127,8 +110102,7 @@ - s_4124: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_meoh_e" - metanetx.reaction: "MNXR101464" @@ -115146,8 +110120,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.1.3.-" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - metanetx.reaction: "MNXR118733" - sbo: "SBO:0000176" @@ -115161,8 +110134,7 @@ - s_4170: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_L_alagly_e" - sbo: "SBO:0000627" @@ -115175,8 +110147,7 @@ - s_4137: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -115188,8 +110159,7 @@ - s_4109: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pala_e" - sbo: "SBO:0000627" @@ -115202,8 +110172,7 @@ - s_4118: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_5dglcn_e" - sbo: "SBO:0000627" @@ -115216,8 +110185,7 @@ - s_4130: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_tag__D_e" - sbo: "SBO:0000627" @@ -115230,8 +110198,7 @@ - s_4131: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -115243,8 +110210,7 @@ - s_4150: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_g6p_e" - sbo: "SBO:0000627" @@ -115257,8 +110223,7 @@ - s_4140: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_malttr_e" - sbo: "SBO:0000627" @@ -115271,8 +110236,7 @@ - s_4145: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_g1p_e" - sbo: "SBO:0000627" @@ -115285,8 +110249,7 @@ - s_4125: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_madg_e" - sbo: "SBO:0000627" @@ -115299,8 +110262,7 @@ - s_4164: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gam_e" - sbo: "SBO:0000627" @@ -115313,8 +110275,7 @@ - s_4167: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_dha_e" - sbo: "SBO:0000627" @@ -115327,8 +110288,7 @@ - s_4034: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ala_L_gln__L_e" - sbo: "SBO:0000627" @@ -115341,8 +110301,7 @@ - s_4168: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -115354,8 +110313,7 @@ - s_4056: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gly_gln__L_e" - sbo: "SBO:0000627" @@ -115368,8 +110326,7 @@ - s_4050: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ala_L_his__L_e" - sbo: "SBO:0000627" @@ -115382,8 +110339,7 @@ - s_4053: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gly_asn__L_e" - sbo: "SBO:0000627" @@ -115396,8 +110352,7 @@ - s_4037: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_LalaLglu_e" - sbo: "SBO:0000627" @@ -115410,8 +110365,7 @@ - s_4085: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gly_met__L_e" - sbo: "SBO:0000627" @@ -115424,8 +110378,7 @@ - s_4119: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ala_L_asp__L_e" - sbo: "SBO:0000627" @@ -115438,8 +110391,7 @@ - s_4059: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gly_glu__L_e" - sbo: "SBO:0000627" @@ -115452,8 +110404,7 @@ - s_4040: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ala_L_Thr__L_e" - sbo: "SBO:0000627" @@ -115466,8 +110417,7 @@ - s_4143: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_met_L_ala__L_e" - sbo: "SBO:0000627" @@ -115480,8 +110430,7 @@ - s_4166: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_citr__L_e" - sbo: "SBO:0000627" @@ -115494,8 +110443,7 @@ - s_4080: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_C02356_e" - sbo: "SBO:0000627" @@ -115508,8 +110456,7 @@ - s_4158: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_cholp_e" - sbo: "SBO:0000627" @@ -115522,8 +110469,7 @@ - s_4049: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -115535,8 +110481,7 @@ - s_4141: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_2pg_e" - sbo: "SBO:0000627" @@ -115549,8 +110494,7 @@ - s_4148: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_gmp_e" - sbo: "SBO:0000627" @@ -115563,8 +110507,7 @@ - s_4147: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pser__L_e" - sbo: "SBO:0000627" @@ -115577,8 +110520,7 @@ - s_4078: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pser__D_e" - sbo: "SBO:0000627" @@ -115591,8 +110533,7 @@ - s_4157: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ppi_e" - sbo: "SBO:0000627" @@ -115605,8 +110546,7 @@ - s_4099: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -115618,8 +110558,7 @@ - s_4152: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_pep_e" - sbo: "SBO:0000627" @@ -115632,8 +110571,7 @@ - s_4093: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_argp_e" - sbo: "SBO:0000627" @@ -115646,8 +110584,7 @@ - s_4146: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -115659,8 +110596,7 @@ - s_4154: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ethamp_e" - sbo: "SBO:0000627" @@ -115673,8 +110609,7 @@ - s_4075: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -115686,8 +110621,7 @@ - s_4067: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -115699,8 +110633,7 @@ - s_4063: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_glyc2p_e" - sbo: "SBO:0000627" @@ -115713,8 +110646,7 @@ - s_4069: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_3gmp_e" - sbo: "SBO:0000627" @@ -115727,8 +110659,7 @@ - s_4070: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_2pglyc_e" - sbo: "SBO:0000627" @@ -115741,8 +110672,7 @@ - s_4155: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_6pgc_e" - sbo: "SBO:0000627" @@ -115755,8 +110685,7 @@ - s_4153: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_man6p_e" - sbo: "SBO:0000627" @@ -115769,8 +110698,7 @@ - s_4095: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_23cgmp_e" - sbo: "SBO:0000627" @@ -115783,8 +110711,7 @@ - s_4097: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_tyrp_e" - sbo: "SBO:0000627" @@ -115797,8 +110724,7 @@ - s_4065: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_thrp_e" - sbo: "SBO:0000627" @@ -115811,8 +110737,7 @@ - s_4142: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_3pg_e" - sbo: "SBO:0000627" @@ -115825,8 +110750,7 @@ - s_4162: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -115838,8 +110762,7 @@ - s_4107: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_3amp_e" - sbo: "SBO:0000627" @@ -115852,8 +110775,7 @@ - s_4161: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_23camp_e" - sbo: "SBO:0000627" @@ -115866,8 +110788,7 @@ - s_4156: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_man1p_e" - sbo: "SBO:0000627" @@ -115880,8 +110801,7 @@ - s_4160: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_amp_e" - sbo: "SBO:0000627" @@ -115894,8 +110814,7 @@ - s_4135: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_C02712_e" - sbo: "SBO:0000627" @@ -115908,8 +110827,7 @@ - s_4176: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_metsox_S__L_e" - sbo: "SBO:0000627" @@ -115922,8 +110840,7 @@ - s_4105: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -115935,8 +110852,7 @@ - s_4111: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_CE1310_e" - sbo: "SBO:0000627" @@ -115949,8 +110865,7 @@ - s_4139: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_Lcyst_e" - sbo: "SBO:0000627" @@ -115963,8 +110878,7 @@ - s_4116: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_isetac_e" - sbo: "SBO:0000627" @@ -115977,8 +110891,7 @@ - s_4133: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_acac_e" - sbo: "SBO:0000627" @@ -115991,8 +110904,7 @@ - s_4172: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_acglu_e" - sbo: "SBO:0000627" @@ -116005,8 +110917,7 @@ - s_4151: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ump_e" - sbo: "SBO:0000627" @@ -116019,8 +110930,7 @@ - s_4163: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_cmp_e" - sbo: "SBO:0000627" @@ -116033,8 +110943,7 @@ - s_4047: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -116046,8 +110955,7 @@ - s_4045: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -116059,8 +110967,7 @@ - s_4101: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -116072,8 +110979,7 @@ - s_4082: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: 10000000 @@ -116085,8 +110991,7 @@ - s_4084: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_3ump_e" - sbo: "SBO:0000627" @@ -116099,8 +111004,7 @@ - s_4127: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_23ccmp_e" - sbo: "SBO:0000627" @@ -116113,8 +111017,7 @@ - s_4103: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_23cump_e" - sbo: "SBO:0000627" @@ -116134,32 +111037,13 @@ - "3.1.3.-" - "3.1.3.2" - "3.1.3.29" - - subsystem: - - "Pentose phosphate pathway" + - subsystem: "Pentose phosphate pathway" - annotation: !!omap - metanetx.reaction: "MNXR123213" - sbo: "SBO:0000176" - deltaG: 10000000 - confidence_score: 0 - rxnNotes: "metabolites observed in metabolomics data (PR #156) | model.S(610,3928) curated (PR #222)" - - !!omap - - id: "r_4568" - - name: "R06790" - - metabolites: !!omap - - s_0794: -1 - - s_1321: -1 - - s_4194: 1 - - lower_bound: 0 - - upper_bound: 1000 - - subsystem: - - "Phenylalanine metabolism" - - annotation: !!omap - - kegg.reaction: "R06790" - - metanetx.reaction: "MNXR139469" - - sbo: "SBO:0000176" - - deltaG: 10000000 - - confidence_score: 0 - - rxnNotes: "metabolites observed in metabolomics data (PR #156) | MetaNetX ID curated (PR #220)" - !!omap - id: "r_4569" - name: "Carboxylic ester hydrolases" @@ -116174,8 +111058,7 @@ - eccodes: - "3.1.1.-" - "3.1.1.2" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - kegg.reaction: "R06893" - metanetx.reaction: "MNXR110621" @@ -116196,8 +111079,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL074C or YER081W" - eccodes: "1.1.1.95" - - subsystem: - - "Glycine, serine and threonine metabolism" + - subsystem: "Glycine, serine and threonine metabolism" - annotation: !!omap - kegg.reaction: "R08198" - metanetx.reaction: "MNXR111769" @@ -116217,8 +111099,7 @@ - s_4183: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Glyoxylate and dicarboxylate metabolism" + - subsystem: "Glyoxylate and dicarboxylate metabolism" - annotation: !!omap - metanetx.reaction: "MNXR134240" - sbo: "SBO:0000176" @@ -116238,8 +111119,7 @@ - eccodes: - "2.6.1.19" - "2.6.1.55" - - subsystem: - - "Beta-alanine metabolism" + - subsystem: "Beta-alanine metabolism" - annotation: !!omap - kegg.reaction: "R00908" - metanetx.reaction: "MNXR95862" @@ -116263,8 +111143,7 @@ - "1.2.1.-" - "1.2.1.18" - "1.2.1.27" - - subsystem: - - "Beta-alanine metabolism" + - subsystem: "Beta-alanine metabolism" - annotation: !!omap - bigg.reaction: "MMSAD3" - kegg.reaction: "R00705" @@ -116288,8 +111167,7 @@ - eccodes: - "1.2.1.-" - "1.2.1.18" - - subsystem: - - "Beta-alanine metabolism" + - subsystem: "Beta-alanine metabolism" - annotation: !!omap - kegg.reaction: "R00706" - metanetx.reaction: "MNXR106650" @@ -116310,8 +111188,7 @@ - eccodes: - "4.1.1.-" - "4.2.1.155" - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - kegg.reaction: "R06973" - metanetx.reaction: "MNXR110693" @@ -116333,8 +111210,7 @@ - eccodes: - "1.1.1.-" - "1.1.1.85" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - bigg.reaction: "ERTHMMOR" - kegg.reaction: "R00994" @@ -116356,8 +111232,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "2.3.3.-" - - subsystem: - - "Glyoxylate and dicarboxylate metabolism" + - subsystem: "Glyoxylate and dicarboxylate metabolism" - annotation: !!omap - metanetx.reaction: "MNXR121603" - sbo: "SBO:0000176" @@ -116378,8 +111253,7 @@ - eccodes: - "3.1.2.-" - "3.1.2.2" - - subsystem: - - "Biosynthesis of unsaturated fatty acids" + - subsystem: "Biosynthesis of unsaturated fatty acids" - annotation: !!omap - bigg.reaction: "FACOAE1829Z12Z" - kegg.reaction: "R08177" @@ -116402,8 +111276,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YOR317W or YER015W or YMR246W or YIL009W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid biosynthesis" + - subsystem: "Fatty acid biosynthesis" - annotation: !!omap - bigg.reaction: "FACOAL1821" - metanetx.reaction: "MNXR99175" @@ -116422,8 +111295,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "3.2.1.22" - - subsystem: - - "Galactose metabolism" + - subsystem: "Galactose metabolism" - annotation: !!omap - bigg.reaction: "STACHGALACT" - kegg.reaction: "R03634" @@ -116442,8 +111314,7 @@ - lower_bound: 0 - upper_bound: 1000 - eccodes: "2.4.1.-" - - subsystem: - - "Galactose metabolism" + - subsystem: "Galactose metabolism" - annotation: !!omap - metanetx.reaction: "MNXR122225" - sbo: "SBO:0000176" @@ -116458,11 +111329,10 @@ - s_0796: -1 - s_3880: 1 - s_4199: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOL122C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR96437" - sbo: "SBO:0000655" @@ -116478,8 +111348,7 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YNL275W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "Clt" - metanetx.reaction: "MNXR96797" @@ -116495,11 +111364,10 @@ - s_0796: -1 - s_4019: 1 - s_4201: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOL122C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR126350" - sbo: "SBO:0000655" @@ -116514,11 +111382,10 @@ - s_0796: -1 - s_3801: 1 - s_4202: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YOL130W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "MNt2" - metanetx.reaction: "MNXR101669" @@ -116534,11 +111401,10 @@ - s_0796: -1 - s_3822: 1 - s_4203: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGL255W or YLR130C" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - bigg.reaction: "r2073_1" - metanetx.reaction: "MNXR105278" @@ -116554,11 +111420,10 @@ - s_0796: -1 - s_4013: 1 - s_4204: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YGR191W or YOL130W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - metanetx.reaction: "MNXR101553" - sbo: "SBO:0000655" @@ -116572,8 +111437,7 @@ - s_4200: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_cl_e" - sbo: "SBO:0000627" @@ -116586,8 +111450,7 @@ - s_4201: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_cu2_e" - sbo: "SBO:0000627" @@ -116600,8 +111463,7 @@ - s_4202: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_mn2_e" - sbo: "SBO:0000627" @@ -116614,8 +111476,7 @@ - s_4203: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_zn2_e" - sbo: "SBO:0000627" @@ -116628,8 +111489,7 @@ - s_4204: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_mg2_e" - sbo: "SBO:0000627" @@ -116642,6 +111502,7 @@ - s_0529: -0.000190000006114133 - s_0687: -9.99999974737875e-06 - s_0750: -1e-06 + - s_0794: -0.0173732001408123 - s_1198: -0.00264999992214143 - s_1203: -0.000150000007124618 - s_1207: -0.000569999974686652 @@ -116653,8 +111514,7 @@ - s_4205: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Growth" + - subsystem: "Growth" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -116664,6 +111524,7 @@ - id: "r_4599" - name: "ion pseudoreaction" - metabolites: !!omap + - s_0794: -0.0224361131513434 - s_0924: -3.04000004689442e-05 - s_1373: -0.00362999993376434 - s_1437: -0.003969999961555 @@ -116677,8 +111538,7 @@ - s_4206: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Growth" + - subsystem: "Growth" - annotation: !!omap - sbo: "SBO:0000395" - deltaG: 10000000 @@ -116691,8 +111551,7 @@ - s_4199: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - bigg.reaction: "EX_ca2_e" - sbo: "SBO:0000627" @@ -116708,8 +111567,7 @@ - s_0801: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - metanetx.reaction: "MNXR94845" - sbo: "SBO:0000655" @@ -116724,8 +111582,7 @@ - s_0363: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR95431" - sbo: "SBO:0000655" @@ -116740,8 +111597,7 @@ - s_3761: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "ADPRIBt" - metanetx.reaction: "MNXR95481" @@ -116757,8 +111613,7 @@ - s_0692: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, lp]" + - subsystem: "Transport [c, lp]" - annotation: !!omap - metanetx.reaction: "MNXR99646" - sbo: "SBO:0000655" @@ -116775,8 +111630,7 @@ - s_1221: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - metanetx.reaction: "MNXR101858" - sbo: "SBO:0000655" @@ -116793,8 +111647,7 @@ - s_1240: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR135002" - sbo: "SBO:0000655" @@ -116809,8 +111662,7 @@ - s_1325: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - bigg.reaction: "PItg" - metanetx.reaction: "MNXR102871" @@ -116831,8 +111683,7 @@ - s_4183: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "r2499" - metanetx.reaction: "MNXR106312" @@ -116848,8 +111699,7 @@ - s_1539: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - bigg.reaction: "UDPtg" - metanetx.reaction: "MNXR105076" @@ -116865,8 +111715,7 @@ - s_1540: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "UDPtg" - metanetx.reaction: "MNXR105076" @@ -116882,8 +111731,7 @@ - s_1546: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - metanetx.reaction: "MNXR105127" - sbo: "SBO:0000655" @@ -116898,8 +111746,7 @@ - s_1622: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - metanetx.reaction: "MNXR104921" - sbo: "SBO:0000655" @@ -116914,8 +111761,7 @@ - s_3677: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - metanetx.reaction: "MNXR99110" - sbo: "SBO:0000655" @@ -116932,8 +111778,7 @@ - s_3751: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "ACTNt2r" - metanetx.reaction: "MNXR95426" @@ -116949,8 +111794,7 @@ - s_3755: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "GLNtm" - metanetx.reaction: "MNXR100259" @@ -116966,8 +111810,7 @@ - s_3781: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR105127" - sbo: "SBO:0000655" @@ -116982,8 +111825,7 @@ - s_3818: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - bigg.reaction: "AMETtn" - metanetx.reaction: "MNXR95809" @@ -116999,8 +111841,7 @@ - s_3831: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR100449" - sbo: "SBO:0000655" @@ -117018,8 +111859,7 @@ - lower_bound: -1000 - upper_bound: 1000 - eccodes: "2.7.4.6" - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR96123" - sbo: "SBO:0000655" @@ -117034,8 +111874,7 @@ - s_3898: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - metanetx.reaction: "MNXR101385" - sbo: "SBO:0000655" @@ -117050,8 +111889,7 @@ - s_3905: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - bigg.reaction: "ACSERtmi" - metanetx.reaction: "MNXR95416" @@ -117067,8 +111905,7 @@ - s_3906: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - metanetx.reaction: "MNXR100494" - sbo: "SBO:0000655" @@ -117085,8 +111922,7 @@ - s_3925: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - metanetx.reaction: "MNXR97002" - sbo: "SBO:0000655" @@ -117104,8 +111940,7 @@ - lower_bound: -1000 - upper_bound: 1000 - eccodes: "2.7.4.6" - - subsystem: - - "Transport [c, erm]" + - subsystem: "Transport [c, erm]" - annotation: !!omap - metanetx.reaction: "MNXR96123" - sbo: "SBO:0000655" @@ -117120,8 +111955,7 @@ - s_4113: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - metanetx.reaction: "MNXR104966" - sbo: "SBO:0000655" @@ -117136,8 +111970,7 @@ - s_4011: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - metanetx.reaction: "MNXR104460" - sbo: "SBO:0000655" @@ -117152,8 +111985,7 @@ - s_4015: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, er]" + - subsystem: "Transport [c, er]" - annotation: !!omap - metanetx.reaction: "MNXR105071" - sbo: "SBO:0000655" @@ -117168,8 +112000,7 @@ - s_4025: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, g]" + - subsystem: "Transport [c, g]" - annotation: !!omap - metanetx.reaction: "MNXR105021" - sbo: "SBO:0000655" @@ -117182,14 +112013,14 @@ - metabolites: !!omap - s_0532: 1 - s_0682: -1 + - s_0799: 4 - s_4211: -1 - s_4212: 1 - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YBR177C or YPL095C" - eccodes: "2.3.1.84" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.reaction: "R00627" - sbo: "SBO:0000176" @@ -117207,8 +112038,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR177C or YPL095C" - eccodes: "2.3.1.84" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.reaction: "R00627" - sbo: "SBO:0000176" @@ -117227,8 +112057,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR177C or YPL095C" - eccodes: "2.3.1.84" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.reaction: "R00627" - sbo: "SBO:0000176" @@ -117246,8 +112075,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR177C or YOR377W or YGR015C" - eccodes: "2.3.1.84" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.reaction: "R00627" - sbo: "SBO:0000176" @@ -117265,8 +112093,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR177C or YPL095C" - eccodes: "2.3.1.84" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.reaction: "R00627" - sbo: "SBO:0000176" @@ -117280,8 +112107,7 @@ - s_4221: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117294,8 +112120,7 @@ - s_4222: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -117309,8 +112134,7 @@ - s_4223: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117323,8 +112147,7 @@ - s_4224: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117337,8 +112160,7 @@ - s_4225: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117351,8 +112173,7 @@ - s_4226: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117365,8 +112186,7 @@ - s_4227: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -117380,8 +112200,7 @@ - s_4228: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117394,8 +112213,7 @@ - s_4229: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117408,8 +112226,7 @@ - s_4230: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117421,8 +112238,7 @@ - s_4226: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -117434,8 +112250,7 @@ - s_4227: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: -523.89 @@ -117448,8 +112263,7 @@ - s_4228: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -117461,8 +112275,7 @@ - s_4229: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -117474,8 +112287,7 @@ - s_4230: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -117492,8 +112304,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR015C" - eccodes: "2.3.1.268" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.reaction: "R11957" - sbo: "SBO:0000176" @@ -117508,8 +112319,7 @@ - s_4231: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -117527,8 +112337,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR087C or YLR044C or YLR134W" - eccodes: "4.1.1.1" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.reaction: "R00636" - sbo: "SBO:0000176" @@ -117551,8 +112360,7 @@ - "1.1.1.-" - "1.1.1.1" - "1.1.1.284" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -117578,8 +112386,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL256W or YMR083W" - eccodes: "1.1.1.1" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -117606,8 +112413,7 @@ - eccodes: - "1.1.1.-" - "1.1.1.2" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -117627,8 +112433,7 @@ - s_4235: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -117642,8 +112447,7 @@ - s_4236: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -117657,8 +112461,7 @@ - s_4237: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -117671,8 +112474,7 @@ - s_4236: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: -110.94 @@ -117685,8 +112487,7 @@ - s_4237: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: -148.61 @@ -117704,8 +112505,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YHR137W" - eccodes: "4.1.1.1" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.reaction: "R00636" - sbo: "SBO:0000176" @@ -117727,8 +112527,7 @@ - "1.1.1.-" - "1.1.1.1" - "1.1.1.284" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -117753,8 +112552,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL256W or YMR083W" - eccodes: "1.1.1.1" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -117780,8 +112578,7 @@ - eccodes: - "1.1.1.-" - "1.1.1.2" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -117800,8 +112597,7 @@ - s_4241: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117814,8 +112610,7 @@ - s_4242: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117828,8 +112623,7 @@ - s_4243: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117841,8 +112635,7 @@ - s_4242: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -117854,8 +112647,7 @@ - s_4243: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -117872,8 +112664,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR087C or YLR044C or YLR134W" - eccodes: "4.1.1.1" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -117894,8 +112685,7 @@ - "1.1.1.-" - "1.1.1.1" - "1.1.1.284" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -117919,8 +112709,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGL256W or YMR083W" - eccodes: "1.1.1.1" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -117946,8 +112735,7 @@ - eccodes: - "1.1.1.-" - "1.1.1.2" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -117966,8 +112754,7 @@ - s_4247: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -117981,8 +112768,7 @@ - s_4248: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -117995,8 +112781,7 @@ - s_4249: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -118009,8 +112794,7 @@ - s_4248: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -118022,8 +112806,7 @@ - s_4249: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: -204.32 @@ -118043,8 +112826,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YMR170C or YMR169C or YOR374W" - eccodes: "1.2.1.5" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00010" @@ -118064,14 +112846,14 @@ - s_0439: -1 - s_0534: -1 - s_0638: 1 + - s_0801: 1 - s_4251: -1 - s_4252: 1 - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "YOR317W or YER015W or YIL009W or YMR246W" - eccodes: "6.2.1.3" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.pathway: - "sce00061" @@ -118094,8 +112876,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR177C or YPL095C" - eccodes: "2.3.1.84" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118108,8 +112889,7 @@ - s_4252: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [p, m]" + - subsystem: "Transport [p, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -118123,8 +112903,7 @@ - s_4215: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [p, m]" + - subsystem: "Transport [p, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -118138,8 +112917,7 @@ - s_4211: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [p, m]" + - subsystem: "Transport [p, m]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118152,8 +112930,7 @@ - s_4213: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [p, m]" + - subsystem: "Transport [p, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -118167,8 +112944,7 @@ - s_4219: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [p, m]" + - subsystem: "Transport [p, m]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -118182,8 +112958,7 @@ - s_4251: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, p]" + - subsystem: "Transport [c, p]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -118201,8 +112976,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR177C or YOR377W or YGR015C" - eccodes: "2.3.1.84" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118215,8 +112989,7 @@ - s_4255: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118228,8 +113001,7 @@ - s_4255: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -118246,8 +113018,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR177C or YOR377W or YGR015C" - eccodes: "2.3.1.84" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118260,8 +113031,7 @@ - s_4257: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118273,8 +113043,7 @@ - s_4257: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -118291,8 +113060,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR177C or YOR377W or YGR015C" - eccodes: "2.3.1.84" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118305,8 +113073,7 @@ - s_4259: 1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118318,8 +113085,7 @@ - s_4259: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -118332,8 +113098,7 @@ - s_4261: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118347,8 +113112,7 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YNL065W or YKL217W" - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118360,8 +113124,7 @@ - s_4262: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -118376,8 +113139,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL166C" - references: "10.1093/femsyr/foy046" - - subsystem: - - "Transport[c, e]" + - subsystem: "Transport[c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -118387,6 +113149,7 @@ - name: "L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming)" - metabolites: !!omap - s_0421: 1 + - s_0799: 1 - s_0807: -1 - s_1401: 1 - s_3785: -1 @@ -118396,8 +113159,7 @@ - gene_reaction_rule: "YFR055W" - eccodes: "4.4.1.28" - references: "10.1093/femsyr/foy046" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - kegg.pathway: "sce00280" - kegg.reaction: "R00782" @@ -118409,6 +113171,7 @@ - name: "L-cysteine:2-oxoglutarate aminotransferase" - metabolites: !!omap - s_0180: -1 + - s_0794: -1 - s_0981: -1 - s_0991: 1 - s_4264: 1 @@ -118416,8 +113179,7 @@ - upper_bound: 1000 - eccodes: "2.6.1.1" - references: "10.1093/femsyr/foy046" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - kegg.pathway: "sce00280" - kegg.reaction: "R00896" @@ -118428,6 +113190,7 @@ - id: "r_4703" - name: "3-mercaptopyruvate sulfurtransferase" - metabolites: !!omap + - s_0794: 1 - s_0841: 1 - s_1399: 1 - s_1616: -1 @@ -118438,28 +113201,12 @@ - gene_reaction_rule: "YOR251C" - eccodes: "2.8.1.2" - references: "10.1093/femsyr/foy046" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - kegg.reaction: "R03105" - sbo: "SBO:0000176" - deltaG: -12.45 - rxnNotes: "Sulfur volatiles curation (PR #296)" - - !!omap - - id: "r_4704" - - name: "alkanesulfonate transport" - - metabolites: !!omap - - s_4265: 1 - - s_4266: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "YIL166C" - - references: "10.1093/femsyr/foy046" - - subsystem: - - "Transport[c, e]" - - annotation: !!omap - - sbo: "SBO:0000655" - - rxnNotes: "Sulfur volatiles curation (PR #296)" - !!omap - id: "r_4705" - name: "taurocholate transport" @@ -118470,36 +113217,16 @@ - upper_bound: 1000 - gene_reaction_rule: "YIL166C" - references: "10.1093/femsyr/foy046" - - subsystem: - - "Transport[c, e]" + - subsystem: "Transport[c, e]" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 - rxnNotes: "Sulfur volatiles curation (PR #296)" - - !!omap - - id: "r_4706" - - name: "alkanesulfonate dioxygenase" - - metabolites: !!omap - - s_0180: -1 - - s_0417: 1 - - s_0456: 1 - - s_1275: -1 - - s_1458: 1 - - s_1469: 1 - - s_4265: -1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "YLL057C" - - references: "10.1093/femsyr/foy046" - - subsystem: - - "Sulfur metabolism" - - annotation: !!omap - - sbo: "SBO:0000176" - - rxnNotes: "Sulfur volatiles curation (PR #296)" - !!omap - id: "r_4707" - name: "trithionate thiosulfohydrolase" - metabolites: !!omap + - s_0794: 1 - s_0803: -1 - s_1467: 1 - s_4113: 1 @@ -118508,8 +113235,7 @@ - upper_bound: 1000 - eccodes: "3.12.1.1" - references: "10.1093/femsyr/foy046" - - subsystem: - - "Sulfur metabolism" + - subsystem: "Sulfur metabolism" - annotation: !!omap - kegg.reaction: "R01930" - sbo: "SBO:0000176" @@ -118523,25 +113249,11 @@ - lower_bound: 0 - upper_bound: 1000 - references: "10.1093/femsyr/foy046" - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - deltaG: -51.44 - rxnNotes: "Sulfur volatiles curation (PR #296)" - - !!omap - - id: "r_4709" - - name: "alkanesulfonate exchange" - - metabolites: !!omap - - s_4266: -1 - - lower_bound: 0 - - upper_bound: 1000 - - references: "10.1093/femsyr/foy046" - - subsystem: - - "Exchange reaction" - - annotation: !!omap - - sbo: "SBO:0000627" - - rxnNotes: "Sulfur volatiles curation (PR #296)" - !!omap - id: "r_4710" - name: "taurocholate exchange" @@ -118550,8 +113262,7 @@ - lower_bound: 0 - upper_bound: 1000 - references: "10.1093/femsyr/foy046" - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - rxnNotes: "Sulfur volatiles curation (PR #296)" @@ -118569,8 +113280,7 @@ - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - references: "10.1006/fmic.1999.0272; 10.1016/j.aca.2009.09.040; 10.1038/s41598-022-16554-z" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118589,8 +113299,7 @@ - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - references: "10.1006/fmic.1999.0272; 10.1016/j.aca.2009.09.040; 10.1038/s41598-022-16554-z" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118605,12 +113314,11 @@ - s_1458: -1 - s_4274: 1 - lower_bound: -1000 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - references: "10.1016/S0889-1575(03)00021-8; 10.1006/fmic.1999.0272; 10.1016/j.aca.2009.09.040; 10.1038/s41598-022-16554-z" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118625,12 +113333,11 @@ - s_1458: -1 - s_4276: 1 - lower_bound: -1000 - - upper_bound: 1000 + - upper_bound: 0 - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - references: "10.1016/S0889-1575(03)00021-8; 10.1038/s41598-022-16554-z" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118649,8 +113356,7 @@ - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - references: "10.1016/j.aca.2009.09.040; 10.1038/s41598-022-16554-z" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118669,8 +113375,7 @@ - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - references: "10.1006/fmic.1999.0272; 10.1038/s41598-022-16554-z" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118689,8 +113394,7 @@ - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - references: "10.1016/j.aca.2009.09.040; 10.1038/s41598-022-16554-z" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118710,8 +113414,7 @@ - gene_reaction_rule: "YOR374W or YPL061W" - eccodes: "1.2.1.3" - references: "10.1042/BSR20160529" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.reaction: "R00538" - sbo: "SBO:0000176" @@ -118732,8 +113435,7 @@ - gene_reaction_rule: "YOR374W or YPL061W" - eccodes: "1.2.1.3" - references: "10.1042/BSR20160529" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - kegg.reaction: "R00538" - sbo: "SBO:0000176" @@ -118753,8 +113455,7 @@ - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - references: "10.1038/s41598-022-16554-z" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118773,8 +113474,7 @@ - gene_reaction_rule: "YOR126C" - eccodes: "3.1.-.-" - references: "10.1038/s41598-022-16554-z" - - subsystem: - - "Fatty acid ester pathway" + - subsystem: "Fatty acid ester pathway" - annotation: !!omap - sbo: "SBO:0000176" - confidence_score: 2 @@ -118793,8 +113493,7 @@ - gene_reaction_rule: "YJL012C" - eccodes: "2.7.4.1" - references: "10.1126/science.1168120; 10.3390/biology10060487" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - kegg.reaction: "R02184" - sbo: "SBO:0000176" @@ -118808,15 +113507,14 @@ - s_0810: -1 - s_1329: 2 - s_4290: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YHR201C or YDR452W" - eccodes: - "3.6.1.10" - "3.6.1.11" - references: "10.1007/s10540-006-9003-2" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - kegg.reaction: "R03042" - metanetx.reaction: "MNXR107906" @@ -118831,15 +113529,14 @@ - s_0807: -1 - s_1326: 2 - s_4291: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YHR201C or YDR452W" - eccodes: - "3.6.1.10" - "3.6.1.11" - references: "10.1016/0014-5793(89)80882-8; 10.1023/a:1023648509241" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - kegg.reaction: "R03042" - sbo: "SBO:0000176" @@ -118853,15 +113550,14 @@ - s_0808: -1 - s_4292: -1 - s_4293: 2 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "YHR201C or YDR452W" - eccodes: - "3.6.1.10" - "3.6.1.11" - references: "10.1002/yea.1391; 10.1007/s10540-006-9003-2" - - subsystem: - - "Oxidative phosphorylation" + - subsystem: "Oxidative phosphorylation" - annotation: !!omap - kegg.reaction: "R03042" - sbo: "SBO:0000176" @@ -118875,8 +113571,7 @@ - s_4271: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118888,8 +113583,7 @@ - s_4270: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -118902,8 +113596,7 @@ - s_4273: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118915,8 +113608,7 @@ - s_4272: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -118929,8 +113621,7 @@ - s_4275: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118942,8 +113633,7 @@ - s_4275: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -118956,8 +113646,7 @@ - s_4277: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118969,8 +113658,7 @@ - s_4277: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -118983,8 +113671,7 @@ - s_4279: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -118996,8 +113683,7 @@ - s_4279: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -119010,8 +113696,7 @@ - s_4281: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -119023,8 +113708,7 @@ - s_4281: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -119037,8 +113721,7 @@ - s_4289: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -119050,8 +113733,7 @@ - s_4289: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -119064,8 +113746,7 @@ - s_4287: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -119077,8 +113758,7 @@ - s_4287: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -119091,8 +113771,7 @@ - s_4284: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, e]" + - subsystem: "Transport [c, e]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 2 @@ -119104,8 +113783,7 @@ - s_4284: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - confidence_score: 2 @@ -119120,8 +113798,7 @@ - s_4290: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, v]" + - subsystem: "Transport [c, v]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 1 @@ -119136,8 +113813,7 @@ - s_4291: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, m]" + - subsystem: "Transport [c, m]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 1 @@ -119152,8 +113828,7 @@ - s_4292: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport [c, n]" + - subsystem: "Transport [c, n]" - annotation: !!omap - sbo: "SBO:0000655" - confidence_score: 1 @@ -119172,8 +113847,7 @@ - gene_reaction_rule: "YNR012W or YDR020C" - eccodes: "2.7.1.48" - references: "doi:10.1007/s002940050482;doi:10.1093/nar/18.17.5279" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - biocyc: "CYTIKIN-RXN" - kegg.pathway: "Pyrimidine metabolism" @@ -119195,8 +113869,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YML070W or YFL053W" - eccodes: "2.7.1.28" - - subsystem: - - "Fructose and mannose metabolism" + - subsystem: "Fructose and mannose metabolism" - annotation: !!omap - biocyc: "TRIOKINASE-RXN" - kegg.pathway: "Fructose and mannose metabolism" @@ -119217,8 +113890,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR209C" - eccodes: "2.4.2.1" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - biocyc: "ADENPHOSPHOR-RXN" - kegg.pathway: "Purine metabolism" @@ -119237,8 +113909,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YBR019C" - eccodes: "5.1.3.3" - - subsystem: - - "Glycolysis / gluconeogenesis" + - subsystem: "Glycolysis / gluconeogenesis" - annotation: !!omap - biocyc: "ALDOSE-1-EPIMERASE-RXN" - kegg.pathway: "Glycolysis / gluconeogenesis" @@ -119260,8 +113931,7 @@ - gene_reaction_rule: "YEL066W or YPR193C" - eccodes: "2.3.1.36" - references: "doi:10.1007/s00203-004-0724-y" - - subsystem: - - "Phenylalanine metabolism" + - subsystem: "Phenylalanine metabolism" - annotation: !!omap - kegg.pathway: "Phenylalanine metabolism" - kegg.reaction: "R03903" @@ -119280,8 +113950,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YPR069C or YLR146C" - eccodes: "2.5.1.16" - - subsystem: - - "Glutathione metabolism" + - subsystem: "Glutathione metabolism" - annotation: !!omap - biocyc: "RXN0-5217" - kegg.pathway: "Glutathione metabolism" @@ -119303,8 +113972,7 @@ - gene_reaction_rule: "YPL214C" - eccodes: "2.5.1.3" - references: "doi:10.1016/S0021-9258(18)43843-4" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - biocyc: "RXN-12610" - kegg.pathway: "Thiamine metabolism" @@ -119326,8 +113994,7 @@ - gene_reaction_rule: "YDR538W" - eccodes: "2.5.1.129" - references: "doi:10.1021/cb5008103" - - subsystem: - - "Riboflavin metabolism" + - subsystem: "Riboflavin metabolism" - annotation: !!omap - kegg.pathway: "Riboflavin metabolism" - kegg.reaction: "R11225" @@ -119348,8 +114015,7 @@ - gene_reaction_rule: "YDL178W or YEL071W" - eccodes: "1.1.99.40" - references: "doi:10.1002/(SICI)1097-0061(19990930)15:13<1377::AID-YEA473>3.0.CO;2-0" - - subsystem: - - "Pyruvate metabolism" + - subsystem: "Pyruvate metabolism" - annotation: !!omap - kegg.pathway: "Pyruvate metabolism" - kegg.reaction: "R11593" @@ -119370,8 +114036,7 @@ - gene_reaction_rule: "YDR400W" - eccodes: "3.2.2.3" - references: "doi:10.1128/AEM.68.3.1336-1343.2002; doi:10.1007/s00294-002-0296-9" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - biocyc: "RXN0-361" - kegg.pathway: "Pyrimidine metabolism" @@ -119393,8 +114058,7 @@ - gene_reaction_rule: "YDR109C" - eccodes: "2.7.1.47" - references: "doi:10.1074/jbc.M116.760744." - - subsystem: - - "Alternate carbon metabolism" + - subsystem: "Alternate carbon metabolism" - annotation: !!omap - biocyc: "D-RIBULOKIN-RXN" - kegg.pathway: "Alternate carbon metabolism" @@ -119413,8 +114077,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YLR209C" - eccodes: "2.4.2.1" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - biocyc: "DEOXYGUANPHOSPHOR-RXN" - kegg.pathway: "Purine metabolism" @@ -119423,27 +114086,6 @@ - rhea: "RHEA:27738" - sbo: "SBO:0000176" - rxnNotes: "New rxns from databases curation (PR #304)" - - !!omap - - id: "r_4759" - - name: "deamino-NAD diphosphatase" - - metabolites: !!omap - - s_0426: 1 - - s_0801: 2 - - s_0809: -1 - - s_4315: -1 - - s_4316: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "YGL067W" - - eccodes: "3.6.1.22" - - subsystem: - - "Nicotinate and nicotinamide metabolism" - - annotation: !!omap - - kegg.pathway: "Nicotinate and nicotinamide metabolism" - - kegg.reaction: "R03004" - - metanetx.reaction: "MNXR190936" - - sbo: "SBO:0000176" - - rxnNotes: "New rxns from databases curation (PR #304)" - !!omap - id: "r_4760" - name: "trans-4-hydroxy-L-proline dehydrogenase" @@ -119457,8 +114099,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YER023W" - eccodes: "1.5.1.2" - - subsystem: - - "Arginine and proline metabolism" + - subsystem: "Arginine and proline metabolism" - annotation: !!omap - kegg.pathway: "Arginine and proline metabolism" - kegg.reaction: "R03291" @@ -119478,8 +114119,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL060W" - eccodes: "2.6.1.7" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - biocyc: "RXN-21859" - kegg.pathway: "Tryptophan metabolism" @@ -119502,8 +114142,7 @@ - gene_reaction_rule: "YDR036C" - eccodes: "3.1.2.4" - references: "doi:10.1016/S0168-6445(03)00017-2" - - subsystem: - - "Valine, leucine and isoleucine metabolism" + - subsystem: "Valine, leucine and isoleucine metabolism" - annotation: !!omap - kegg.pathway: "Valine, leucine and isoleucine metabolism" - kegg.reaction: "R05064" @@ -119524,8 +114163,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YAL061W or YAL060W" - eccodes: "1.1.1.-" - - subsystem: - - "Butanoate metabolism" + - subsystem: "Butanoate metabolism" - annotation: !!omap - biocyc: "RXN-11034" - kegg.pathway: "Butanoate metabolism" @@ -119547,8 +114185,7 @@ - gene_reaction_rule: "YPR062W" - eccodes: "3.5.4.1" - references: "doi:10.1007/s002940050482;doi:10.1007/s002940050169" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - biocyc: "RXN-14197" - kegg.pathway: "Pyrimidine metabolism" @@ -119569,8 +114206,7 @@ - gene_reaction_rule: "YIR032C" - eccodes: "4.3.2.3" - references: "doi:10.1128/mcb.5.9.2279-2288.1985" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - biocyc: "UREIDOGLYCOLATE-LYASE-RXN" - kegg.pathway: "Purine metabolism" @@ -119588,8 +114224,7 @@ - gene_reaction_rule: "YJL005W" - eccodes: "4.6.1.2" - references: "doi:10.1016/0092-8674(85)90179-5" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - biocyc: "GUANYLCYC-RXN" - kegg.pathway: "Purine metabolism" @@ -119610,8 +114245,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YJL060W" - eccodes: "2.6.1.7" - - subsystem: - - "Tryptophan metabolism" + - subsystem: "Tryptophan metabolism" - annotation: !!omap - biocyc: "RXN-21858" - kegg.pathway: "Tryptophan metabolism" @@ -119633,8 +114267,7 @@ - gene_reaction_rule: "YDR481C" - eccodes: "3.1.7.6" - references: "doi:10.1111/j.1432-1033.1991.tb15803.x" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - biocyc: "RXN-8617_c" - kegg.pathway: "Thiamine metabolism" @@ -119654,8 +114287,7 @@ - gene_reaction_rule: "YDR305C" - eccodes: "3.6.1.29" - references: "doi:10.1186/1471-2199-3-7;doi:10.1128/JB.180.9.2345-2349.1998" - - subsystem: - - "Purine metabolism" + - subsystem: "Purine metabolism" - annotation: !!omap - kegg.pathway: "Purine metabolism" - kegg.reaction: "R00187" @@ -119676,8 +114308,7 @@ - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - references: "doi:10.1016/0003-9861(91)90129-7;doi:10.1007/s10863-006-9045-y;doi:10.1021/bi00830a026" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - kegg.pathway: "Pyrimidine metabolism" - kegg.reaction: "R00139" @@ -119697,8 +114328,7 @@ - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - references: "doi:10.1016/0003-9861(91)90129-7;doi:10.1007/s10863-006-9045-y;doi:10.1021/bi00830a026" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - kegg.pathway: "Pyrimidine metabolism" - kegg.reaction: "R00139" @@ -119718,8 +114348,7 @@ - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - references: "doi:10.1016/0003-9861(91)90129-7;doi:10.1007/s10863-006-9045-y;doi:10.1021/bi00830a026" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - kegg.pathway: "Pyrimidine metabolism" - kegg.reaction: "R00139" @@ -119739,8 +114368,7 @@ - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - references: "doi:10.1016/0003-9861(91)90129-7;doi:10.1007/s10863-006-9045-y;doi:10.1021/bi00830a026" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - kegg.pathway: "Pyrimidine metabolism" - kegg.reaction: "R00139" @@ -119760,8 +114388,7 @@ - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - references: "doi:10.1016/0003-9861(91)90129-7;doi:10.1007/s10863-006-9045-y;doi:10.1021/bi00830a026" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - kegg.pathway: "Pyrimidine metabolism" - kegg.reaction: "R00139" @@ -119781,8 +114408,7 @@ - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - references: "doi:10.1016/0003-9861(91)90129-7;doi:10.1007/s10863-006-9045-y;doi:10.1021/bi00830a026" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - kegg.pathway: "Pyrimidine metabolism" - kegg.reaction: "R00139" @@ -119802,8 +114428,7 @@ - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - references: "doi:10.1016/0003-9861(91)90129-7;doi:10.1007/s10863-006-9045-y;doi:10.1021/bi00830a026" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - kegg.pathway: "Pyrimidine metabolism" - kegg.reaction: "R00139" @@ -119823,8 +114448,7 @@ - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - references: "doi:10.1016/0003-9861(91)90129-7;doi:10.1007/s10863-006-9045-y;doi:10.1021/bi00830a026" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - kegg.pathway: "Pyrimidine metabolism" - kegg.reaction: "R00139" @@ -119844,8 +114468,7 @@ - gene_reaction_rule: "YKL067W" - eccodes: "2.7.4.6" - references: "doi:10.1016/0003-9861(91)90129-7;doi:10.1007/s10863-006-9045-y;doi:10.1021/bi00830a026" - - subsystem: - - "Pyrimidine metabolism" + - subsystem: "Pyrimidine metabolism" - annotation: !!omap - kegg.pathway: "Pyrimidine metabolism" - kegg.reaction: "R00139" @@ -119860,8 +114483,7 @@ - s_4332: 1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: - - "Transport between c and e" + - subsystem: "Transport between c and e" - annotation: !!omap - sbo: "SBO:0000655" - deltaG: 0 @@ -119873,8 +114495,7 @@ - s_4332: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: - - "Exchange reaction" + - subsystem: "Exchange reaction" - annotation: !!omap - sbo: "SBO:0000627" - !!omap @@ -119891,8 +114512,7 @@ - upper_bound: 1000 - gene_reaction_rule: "YGR144W" - references: "10.1021/ja067606t" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - kegg.pathway: "sce00730" - kegg.reaction: "R10685" @@ -119915,14 +114535,45 @@ - gene_reaction_rule: "YGR144W" - eccodes: "2.4.2.60" - references: "10.1021/ja067606t" - - subsystem: - - "Thiamine metabolism" + - subsystem: "Thiamine metabolism" - annotation: !!omap - kegg.pathway: "sce00730" - kegg.reaction: "R10711" - metanetx.reaction: "MNXR139812" - sbo: "SBO:0000176" - confidence_score: 3 + - !!omap + - id: "r_4783" + - name: "oxaloacetate/sulphate antiport, mitochondrial" + - metabolites: !!omap + - s_1271: -1 + - s_1273: 1 + - s_1467: 1 + - s_4333: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "YKL120W" + - references: "10.1074/jbc.274.32.22184" + - subsystem: "Transport [c, m]" + - annotation: !!omap + - sbo: "SBO:0000655" + - confidence_score: 3 + - !!omap + - id: "r_4784" + - name: "malate/sulphate antiport, mitochondrial" + - metabolites: !!omap + - s_0066: -1 + - s_0068: 1 + - s_1467: 1 + - s_4333: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "YKL120W" + - references: "10.1074/jbc.274.32.22184" + - subsystem: "Transport [c, m]" + - annotation: !!omap + - sbo: "SBO:0000655" + - confidence_score: 3 - genes: - !!omap - id: "Q0045" @@ -120537,11 +115188,6 @@ - name: "ILV6" - annotation: !!omap - uniprot: "P25605" - - !!omap - - id: "YCL017C" - - name: "NFS1" - - annotation: !!omap - - uniprot: "P25374" - !!omap - id: "YCL018W" - name: "LEU2" @@ -120977,11 +115623,6 @@ - name: "TPI1" - annotation: !!omap - uniprot: "P00942" - - !!omap - - id: "YDR051C" - - name: "DET1" - - annotation: !!omap - - uniprot: "Q99288" - !!omap - id: "YDR058C" - name: "TGL2" @@ -121310,11 +115951,6 @@ - name: "ADE8" - annotation: !!omap - uniprot: "P04161" - - !!omap - - id: "YDR410C" - - name: "STE14" - - annotation: !!omap - - uniprot: "P32584" - !!omap - id: "YDR428C" - name: "BNA7" @@ -121325,11 +115961,6 @@ - name: "GPI19" - annotation: !!omap - uniprot: "Q04082" - - !!omap - - id: "YDR440W" - - name: "DOT1" - - annotation: !!omap - - uniprot: "Q04089" - !!omap - id: "YDR441C" - name: "APT2" @@ -121893,11 +116524,6 @@ - name: "ERG4" - annotation: !!omap - uniprot: "P25340" - - !!omap - - id: "YGL017W" - - name: "ATE1" - - annotation: !!omap - - uniprot: "P16639" - !!omap - id: "YGL026C" - name: "TRP5" @@ -122615,11 +117241,6 @@ - name: "COX23" - annotation: !!omap - uniprot: "P38824" - - !!omap - - id: "YHR119W" - - name: "SET1" - - annotation: !!omap - - uniprot: "P38827" - !!omap - id: "YHR123W" - name: "EPT1" @@ -122869,11 +117490,6 @@ - name: "HYR1" - annotation: !!omap - uniprot: "P40581" - - !!omap - - id: "YIR038C" - - name: "GTT1" - - annotation: !!omap - - uniprot: "P40582" - !!omap - id: "YJL003W" - name: "COX16" @@ -122903,11 +117519,6 @@ - name: "YJL045W" - annotation: !!omap - uniprot: "P47052" - - !!omap - - id: "YJL046W" - - name: "AIM22" - - annotation: !!omap - - uniprot: "P47051" - !!omap - id: "YJL052W" - name: "TDH1" @@ -123013,11 +117624,6 @@ - name: "ERG20" - annotation: !!omap - uniprot: "P08524" - - !!omap - - id: "YJL168C" - - name: "SET2" - - annotation: !!omap - - uniprot: "P46995" - !!omap - id: "YJL196C" - name: "ELO1" @@ -123633,11 +118239,6 @@ - name: "YLL058W" - annotation: !!omap - uniprot: "Q12198" - - !!omap - - id: "YLL060C" - - name: "GTT2" - - annotation: !!omap - - uniprot: "Q12390" - !!omap - id: "YLL061W" - name: "MMP1" @@ -123733,11 +118334,6 @@ - name: "SUL2" - annotation: !!omap - uniprot: "Q12325" - - !!omap - - id: "YLR099C" - - name: "ICT1" - - annotation: !!omap - - uniprot: "Q12385" - !!omap - id: "YLR100W" - name: "ERG27" @@ -123773,11 +118369,6 @@ - name: "PUT1" - annotation: !!omap - uniprot: "P09368" - - !!omap - - id: "YLR143W" - - name: "DPH6" - - annotation: !!omap - - uniprot: "Q12429" - !!omap - id: "YLR146C" - name: "SPE4" @@ -123872,11 +118463,6 @@ - name: "THI7" - annotation: !!omap - uniprot: "Q05998" - - !!omap - - id: "YLR239C" - - name: "LIP2" - - annotation: !!omap - - uniprot: "Q06005" - !!omap - id: "YLR240W" - name: "VPS34" @@ -124375,11 +118961,6 @@ - name: "GAD1" - annotation: !!omap - uniprot: "Q04792" - - !!omap - - id: "YMR251W" - - name: "GTO3" - - annotation: !!omap - - uniprot: "Q05827" - !!omap - id: "YMR256C" - name: "COX7" @@ -124879,11 +119460,6 @@ - name: "HST1" - annotation: !!omap - uniprot: "P53685" - - !!omap - - id: "YOL075C" - - name: "YOL075C" - - annotation: !!omap - - uniprot: "Q08234" - !!omap - id: "YOL077W-A" - name: "ATP19" @@ -125144,11 +119720,6 @@ - name: "THI72" - annotation: !!omap - uniprot: "Q08579" - - !!omap - - id: "YOR196C" - - name: "LIP5" - - annotation: !!omap - - uniprot: "P32875" - !!omap - id: "YOR202W" - name: "HIS3" @@ -125169,11 +119740,6 @@ - name: "ODC2" - annotation: !!omap - uniprot: "Q99297" - - !!omap - - id: "YOR226C" - - name: "ISU2" - - annotation: !!omap - - uniprot: "Q12056" - !!omap - id: "YOR236W" - name: "DFR1" @@ -125478,11 +120044,6 @@ - name: "ODC1" - annotation: !!omap - uniprot: "Q03028" - - !!omap - - id: "YPL135W" - - name: "ISU1" - - annotation: !!omap - - uniprot: "Q03020" - !!omap - id: "YPL147W" - name: "PXA1" From 9676af17ff16914bef2329a25ae9900b356f10c2 Mon Sep 17 00:00:00 2001 From: Eduard Kerkhoven Date: Wed, 1 Jul 2026 01:08:09 +0200 Subject: [PATCH 3/3] fix: correct constraints nLimit and GCV functions --- code/otherChanges/glycineNitrogenSource.m | 12 ++++++------ code/otherChanges/nitrogenLimitation.m | 6 +++--- 2 files changed, 9 insertions(+), 9 deletions(-) diff --git a/code/otherChanges/glycineNitrogenSource.m b/code/otherChanges/glycineNitrogenSource.m index e333e188..efcaada5 100644 --- a/code/otherChanges/glycineNitrogenSource.m +++ b/code/otherChanges/glycineNitrogenSource.m @@ -11,11 +11,11 @@ % Glycine cleavage is only active when glycine is used as sole nitrogen % source. See doi:10.1111/j.1567-1364.2002.tb00069.x; % doi:10.1074/jbc.274.15.10523; doi:10.1128/EC.2.5.827-829.2003 -model.ub(strcmp(model.rxns,'r_0501'))=0; %glycine cleavage, mitochondrion -model.lb(strcmp(model.rxns,'r_0501'))=1000; -model.ub(strcmp(model.rxns,'r_0507'))=0; %glycine cleavage complex (lipoylprotein), mitochondrion -model.lb(strcmp(model.rxns,'r_0507'))=1000; -model.ub(strcmp(model.rxns,'r_0509'))=0; %glycine cleavage complex (lipoamide), mitochondrion -model.lb(strcmp(model.rxns,'r_0509'))=1000; +model.lb(strcmp(model.rxns,'r_0501'))=0; %glycine cleavage, mitochondrion +model.ub(strcmp(model.rxns,'r_0501'))=1000; +model.lb(strcmp(model.rxns,'r_0507'))=0; %glycine cleavage complex (lipoylprotein), mitochondrion +model.ub(strcmp(model.rxns,'r_0507'))=1000; +model.lb(strcmp(model.rxns,'r_0509'))=0; %glycine cleavage complex (lipoamide), mitochondrion +model.ub(strcmp(model.rxns,'r_0509'))=1000; end \ No newline at end of file diff --git a/code/otherChanges/nitrogenLimitation.m b/code/otherChanges/nitrogenLimitation.m index 4a235209..7f8f3bc0 100644 --- a/code/otherChanges/nitrogenLimitation.m +++ b/code/otherChanges/nitrogenLimitation.m @@ -10,7 +10,7 @@ % Glutamine synthase is repressed when nitrogen is in excess. See doi:10.1128/EC.2.5.827-829.2003 model.ub(strcmp(model.rxns,'r_0472'))=1000; % Glycine cleavage system is repressed when nitrogen (non-glycine) is in excess -model.lb(strcmp(model.rxns,'r_0501'))=1000; %glycine cleavage, mitochondrion -model.lb(strcmp(model.rxns,'r_0507'))=1000; %glycine cleavage complex (lipoylprotein), mitochondrion -model.lb(strcmp(model.rxns,'r_0509'))=1000; %glycine cleavage complex (lipoamide), mitochondrion +model.ub(strcmp(model.rxns,'r_0501'))=1000; +model.ub(strcmp(model.rxns,'r_0507'))=1000; +model.ub(strcmp(model.rxns,'r_0509'))=1000; end