Macenko normalization offers a way to make the quality of H&E images more consistent and might be valuable to make the image registration (and especially the color deconvolution) more robust.
https://www.geeksforgeeks.org/machine-learning/macenko-method-for-normalizing-histology-slides-for-quantitative-analysis/
Macenko normalization offers a way to make the quality of H&E images more consistent and might be valuable to make the image registration (and especially the color deconvolution) more robust.
https://www.geeksforgeeks.org/machine-learning/macenko-method-for-normalizing-histology-slides-for-quantitative-analysis/