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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="UTF-8">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<title>Ahmed Negida, MD, PhD | Translational Research Scientist · Multimodal Neuroimaging Biomarkers in Neurodegeneration</title>
<meta name="description" content="Ahmed Negida - Translational and Clinical Research Scientist at Virginia Commonwealth University specializing in Parkinson's Disease, Lewy Body Dementia, Neuroimaging, Machine Learning, and Precision Medicine.">
<meta name="keywords" content="Ahmed Negida, Parkinson's Disease, Lewy Body Dementia, Neuroimaging, Precision Medicine, Machine Learning, Clinical Research, VCU">
<meta name="author" content="Ahmed Negida">
<!-- Open Graph -->
<meta property="og:title" content="Ahmed Negida, MD, PhD | Translational Research Scientist · Multimodal Neuroimaging Biomarkers in Neurodegeneration">
<meta property="og:description" content="Precision medicine approaches to neurodegenerative diseases through multimodal biomarkers and advanced computational methods.">
<meta property="og:type" content="website">
<meta property="og:url" content="https://negidamd.github.io/">
<meta property="og:image" content="https://negidamd.github.io/photo.jpg">
<meta property="og:image:alt" content="Ahmed Negida, MD, PhD">
<!-- Twitter Card -->
<meta name="twitter:card" content="summary_large_image">
<meta name="twitter:title" content="Ahmed Negida, MD, PhD | Translational Research Scientist · Multimodal Neuroimaging Biomarkers in Neurodegeneration">
<meta name="twitter:description" content="Precision medicine approaches to neurodegenerative diseases through multimodal biomarkers and advanced computational methods.">
<meta name="twitter:image" content="https://negidamd.github.io/photo.jpg">
<meta name="theme-color" content="#162e51">
<!-- Fonts — Public Sans (USWDS / NIH official) + Merriweather (USWDS serif) -->
<link rel="preconnect" href="https://fonts.googleapis.com">
<link rel="preconnect" href="https://fonts.gstatic.com" crossorigin>
<link href="https://fonts.googleapis.com/css2?family=Public+Sans:wght@400;500;600;700;800;900&family=Merriweather:wght@400;700;900&display=swap" rel="stylesheet">
<!-- Leaflet.js for interactive map -->
<link rel="stylesheet" href="https://unpkg.com/leaflet@1.9.4/dist/leaflet.css" />
<script src="https://unpkg.com/leaflet@1.9.4/dist/leaflet.js"></script>
<!-- Chart.js for publication metrics -->
<script src="https://cdn.jsdelivr.net/npm/chart.js@4.4.0/dist/chart.umd.min.js"></script>
<!-- Favicon -->
<link rel="icon" type="image/svg+xml" href="data:image/svg+xml,<svg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 100 100'><text y='.9em' font-size='90'>🧠</text></svg>">
<!-- JSON-LD structured data for search engines -->
<script type="application/ld+json">
{
"@context": "https://schema.org",
"@type": "Person",
"name": "Ahmed Negida",
"jobTitle": "Translational Research Scientist, Multimodal Neuroimaging Biomarkers in Neurodegeneration",
"honorificSuffix": "MD, PhD",
"worksFor": {
"@type": "Organization",
"name": "Virginia Commonwealth University",
"department": "Department of Neurology, Parkinson's and Movement Disorders Center"
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"image": "https://negidamd.github.io/photo.jpg",
"sameAs": [
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"knowsAbout": ["Parkinson's disease", "Lewy body dementia", "Neuroimaging", "Precision medicine", "Machine learning", "Clinical research"],
"description": "Translational and clinical research scientist specializing in neurodegenerative diseases, multimodal biomarkers, and precision medicine."
}
</script>
<style>
:root {
/* USWDS / NIH color palette */
--bg-primary: #ffffff;
--bg-light: #f0f0f0;
--bg-lighter: #f5f6fa;
--text-primary: #1b1b1b;
--text-secondary: #3d4551;
--text-muted: #71767a;
--accent: #005ea2;
--accent-light: #73b3e7;
--accent-dark: #1a4480;
--accent-darker: #162e51;
--border: #c6cace;
--border-light: #dfe1e2;
--font-serif: 'Merriweather', Georgia, 'Times New Roman', serif;
--font-sans: 'Public Sans', -apple-system, BlinkMacSystemFont, 'Segoe UI', sans-serif;
--max-width: 1000px;
}
* { margin: 0; padding: 0; box-sizing: border-box; }
html { scroll-behavior: smooth; font-size: 17px; }
body {
font-family: var(--font-sans);
background: var(--bg-primary);
color: var(--text-primary);
line-height: 1.75;
font-size: 1rem;
}
a { color: var(--accent); text-decoration: underline; }
a:hover { color: var(--accent-dark); }
a:focus-visible, button:focus-visible {
outline: 2px solid var(--accent-light);
outline-offset: 2px;
}
.skip-link {
position: absolute;
top: -3rem;
left: 1rem;
background: var(--accent);
color: #fff;
padding: 0.5rem 1rem;
font-weight: 600;
z-index: 1001;
text-decoration: none;
border-radius: 0.25rem;
transition: top 0.2s ease;
}
.skip-link:focus {
top: 0.5rem;
outline: 2px solid #fff;
outline-offset: 2px;
}
/* ===== Navigation (NIH-style dark header) ===== */
nav {
position: fixed; top: 0; left: 0; right: 0;
background: var(--accent-darker);
z-index: 1000;
}
nav .nav-inner {
max-width: var(--max-width); margin: 0 auto;
display: flex; justify-content: space-between; align-items: center;
padding: 0.55rem 2rem;
}
nav .logo {
font-family: var(--font-sans); font-size: 1.05rem;
font-weight: 700; color: #ffffff; text-decoration: none;
letter-spacing: 0.01em;
}
nav .logo span { color: var(--accent-light); }
nav .nav-links { display: flex; gap: 0; list-style: none; align-items: center; }
nav .nav-links a {
color: rgba(255,255,255,0.85); text-decoration: none;
font-size: 0.8rem; font-weight: 600;
padding: 0.45rem 0.7rem;
letter-spacing: 0.01em;
}
nav .nav-links a:hover, nav .nav-links a.active {
color: #ffffff; text-decoration: none; background: rgba(255,255,255,0.1);
}
.nav-dropdown { position: relative; }
.nav-dropdown > a { cursor: pointer; }
.nav-dropdown-menu {
display: none; position: absolute; top: 100%; right: 0;
background: var(--accent-darker); border: 1px solid rgba(255,255,255,0.15);
min-width: 210px; z-index: 1001; padding: 0.3rem 0;
}
.nav-dropdown:hover .nav-dropdown-menu { display: block; }
.nav-dropdown-menu a {
display: block; padding: 0.45rem 1rem; font-size: 0.78rem;
color: rgba(255,255,255,0.85);
}
.nav-dropdown-menu a:hover { color: #fff; background: rgba(255,255,255,0.1); }
.mobile-menu {
display: none; background: none; border: none; cursor: pointer; padding: 0.5rem;
}
.mobile-menu span {
display: block; width: 22px; height: 2px;
background: #ffffff; margin: 5px 0;
}
/* ===== Hero ===== */
.hero {
padding: 5rem 2rem 2rem;
border-bottom: 3px solid var(--accent);
background: var(--bg-primary);
}
.hero-inner {
max-width: var(--max-width); margin: 0 auto;
display: grid; grid-template-columns: 160px 1fr; gap: 2rem; align-items: start;
}
.profile-photo {
width: 160px; height: 200px;
overflow: hidden; border: 1px solid var(--border);
}
.profile-photo img { width: 100%; height: 100%; object-fit: cover; }
.profile-placeholder {
width: 100%; height: 100%; display: flex; align-items: center;
justify-content: center; font-size: 3.5rem; color: var(--text-muted); background: #f5f5f5;
}
.hero-content h1 {
font-family: var(--font-serif); font-size: 2rem;
font-weight: 900; line-height: 1.25; margin-bottom: 0.15rem;
color: var(--accent-darker);
}
.hero-content .credentials {
font-size: 1.1rem; color: var(--accent); font-weight: 700; margin-bottom: 0.4rem;
}
.hero-content .subtitle {
font-size: 1rem; color: var(--text-secondary);
margin-bottom: 0.6rem; font-style: italic;
}
.hero-content .affiliation {
color: var(--text-secondary); font-size: 0.92rem;
margin-bottom: 1rem; line-height: 1.55;
}
.professional-summary {
font-size: 0.92rem; line-height: 1.8; color: var(--text-secondary);
margin-bottom: 1rem;
}
.hero-links { display: flex; gap: 0.75rem; flex-wrap: wrap; }
.btn {
display: inline-flex; align-items: center; gap: 0.4rem;
padding: 0.6rem 1.25rem; font-size: 0.82rem; font-weight: 700;
text-decoration: none; border: none; cursor: pointer;
border-radius: 0.25rem; letter-spacing: 0.02em;
}
.btn:hover { text-decoration: none; }
.btn-primary { background: var(--accent); color: white; }
.btn-primary:hover { background: var(--accent-dark); text-decoration: none; }
.btn-secondary {
background: var(--bg-primary); color: var(--accent);
border: 2px solid var(--accent);
}
.btn-secondary:hover { background: var(--accent); color: white; }
/* ===== Metrics Bar ===== */
.metrics-bar {
padding: 1.2rem 2rem;
background: var(--accent-darker);
color: #ffffff;
}
.metrics-inner {
max-width: var(--max-width); margin: 0 auto;
display: flex; justify-content: space-between; gap: 1rem; flex-wrap: wrap;
}
.metric-item { text-align: center; flex: 1; min-width: 70px; }
.metric-number {
font-size: 1.35rem; font-weight: 800; color: #ffffff; line-height: 1;
}
.metric-label {
font-size: 0.65rem; color: rgba(255,255,255,0.7); margin-top: 0.2rem;
text-transform: uppercase; letter-spacing: 0.05em; font-weight: 600;
}
/* ===== Section Styles ===== */
section {
padding: 2.75rem 2rem;
border-bottom: 1px solid var(--border-light);
}
section:last-of-type { border-bottom: none; }
.section-inner { max-width: var(--max-width); margin: 0 auto; }
.section-header { margin-bottom: 1.5rem; }
.section-header h2 {
font-family: var(--font-serif); font-size: 1.4rem; font-weight: 900;
color: var(--accent-darker);
padding-bottom: 0.5rem; border-bottom: 3px solid var(--accent);
display: inline-block;
text-transform: uppercase; letter-spacing: 0.04em;
}
.section-header p {
color: var(--text-muted); font-size: 0.9rem; margin-top: 0.6rem;
}
/* ===== Fade-in Animation ===== */
.fade-in {
opacity: 0; transform: translateY(12px);
transition: opacity 0.5s ease, transform 0.5s ease;
}
.fade-in.visible { opacity: 1; transform: translateY(0); }
@media (prefers-reduced-motion: reduce) {
html { scroll-behavior: auto; }
.fade-in { opacity: 1; transform: none; transition: none; }
.research-card:hover { transform: none; }
}
/* ===== Research Cards ===== */
.research-vision-text {
font-size: 0.95rem; line-height: 1.8; color: var(--text-secondary);
margin-bottom: 2rem;
}
.research-cards {
display: grid; grid-template-columns: repeat(3, 1fr); gap: 1.5rem;
}
.research-card {
border: 1px solid var(--border); overflow: hidden;
transition: transform 0.2s ease, box-shadow 0.2s ease;
}
.research-card:hover {
transform: translateY(-3px);
box-shadow: 0 6px 20px rgba(0,0,0,0.1);
}
.research-card-img {
height: 180px; background-size: cover; background-position: center;
position: relative;
}
.research-card-img::after {
content: ''; position: absolute; inset: 0;
background: linear-gradient(to bottom, rgba(22,46,81,0.15) 0%, rgba(22,46,81,0.65) 100%);
}
.research-card-label {
position: absolute; top: 0.75rem; left: 0.75rem; z-index: 1;
background: var(--accent); color: #fff;
font-size: 0.65rem; font-weight: 700; text-transform: uppercase;
letter-spacing: 0.08em; padding: 0.25rem 0.6rem;
}
.research-card-body {
padding: 1.25rem;
}
.research-card-body h3 {
font-family: var(--font-serif); font-size: 1rem; font-weight: 700;
color: var(--accent-darker); margin-bottom: 0.5rem; line-height: 1.35;
}
.research-card-body p {
color: var(--text-secondary); font-size: 0.85rem; line-height: 1.65;
margin-bottom: 0.5rem;
}
.theme-keywords {
font-size: 0.75rem; color: var(--text-muted); font-style: italic;
}
/* ===== Timeline (Appointments / Education) ===== */
.timeline { }
.timeline-item {
padding-left: 1.25rem; padding-bottom: 1.75rem; position: relative;
border-left: 2px solid var(--border);
}
.timeline-item:last-child { padding-bottom: 0; }
.timeline-item::before {
content: ''; position: absolute; left: -5px; top: 0.3rem;
width: 8px; height: 8px; border-radius: 50%; background: var(--accent);
}
.timeline-date {
font-size: 0.82rem; color: var(--accent); font-weight: 600; margin-bottom: 0.15rem;
}
.timeline-item h3 {
font-family: var(--font-serif); font-size: 1.08rem;
font-weight: normal; color: var(--text-primary); margin-bottom: 0.1rem;
}
.timeline-item h4 {
font-size: 0.9rem; font-weight: 500; color: var(--text-secondary); margin-bottom: 0.4rem;
}
.timeline-item p {
color: var(--text-muted); font-size: 0.88rem; line-height: 1.65;
}
.timeline-item ul { list-style: none; margin-top: 0.35rem; }
.timeline-item ul li {
color: var(--text-muted); font-size: 0.88rem; line-height: 1.6;
padding: 0.2rem 0; padding-left: 0.9rem; position: relative;
}
.timeline-item ul li::before {
content: '\2013'; color: var(--accent); position: absolute; left: 0;
}
.subsection-title {
font-family: var(--font-serif); font-size: 1.12rem; font-weight: 700;
color: var(--accent-dark); margin-bottom: 1.25rem; margin-top: 2.25rem;
padding-bottom: 0.3rem; border-bottom: 1px solid var(--border);
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<h1>Ahmed Negida</h1>
<div class="credentials">MD, PhD</div>
<p class="subtitle">Translational Research Scientist · Multimodal Neuroimaging Biomarkers in Neurodegeneration</p>
<p class="affiliation">
Postdoctoral Scholar<br>
VCU Parkinson's & Movement Disorders Center<br>
Department of Neurology, Virginia Commonwealth University
</p>
<p class="professional-summary">
Translational research scientist developing multimodal neuroimaging biomarkers of neurodegeneration across the Alzheimer's disease and related dementias (AD/ADRD) and Parkinson's disease spectrum, with the goal of stratifying patients for personalized therapeutic trials and tracking disease progression. My first-author work established Parkinson's disease mild cognitive impairment with MRI evidence of nucleus basalis of Meynert (Ch4) cholinergic degeneration as a novel clinical-imaging subtype—the discovery anchoring my independent research program. I integrate structural, diffusion (free-water), and functional MRI with EEG and large-scale longitudinal datasets (PPMI, ADNI, NACC, PDBP), and have released open-access tools including an imaging-based Ch4 subtyping tool and a deep-learning pipeline for MRI-based Parkinson's detection. Research Fellow at Harvard Medical School (2021–2023), Postdoctoral Scholar in Neurology at Virginia Commonwealth University, and 2025 IMPACT-AD Fellow (National Institute on Aging). Founder of a global research training academy (35,000+ trainees across 20+ countries) and co-founder of the Global NeuroSurg research collaborative.
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<h2>Research Program</h2>
<p>Multimodal imaging biomarkers to subtype patients for personalized trials and track disease progression across the AD/ADRD and Parkinson's spectrum</p>
</div>
<p class="research-vision-text">
My long-term goal is to direct an independent multimodal imaging-biomarker program that develops and validates biomarker signatures of neurodegeneration across the Alzheimer's disease and related dementias (AD/ADRD) and Parkinson's disease spectrum, in order to (1) stratify patients into biologically meaningful subtypes for personalized therapeutic trials and (2) track disease progression. Disease-modifying trials often fail because heterogeneous populations are treated as uniform entities—a bottleneck that multimodal, cross-disease imaging-biomarker characterization can help solve. I integrate structural, diffusion (free-water), and functional MRI with EEG and large-scale longitudinal datasets (PPMI, ADNI, NACC, PDBP).
</p>
<div style="display: flex; flex-wrap: wrap; align-items: center; gap: 0.5rem; margin: 0.25rem 0 1.75rem;">
<span style="font-size: 0.78rem; font-weight: 700; text-transform: uppercase; letter-spacing: 0.05em; color: var(--text-muted); margin-right: 0.25rem;">Disease Areas</span>
<span style="display: inline-block; background: var(--bg-lighter); border: 1px solid var(--border-light); color: var(--accent-dark); border-radius: 999px; padding: 0.3rem 0.85rem; font-size: 0.85rem; font-weight: 600;">Parkinson's Disease</span>
<span style="display: inline-block; background: var(--bg-lighter); border: 1px solid var(--border-light); color: var(--accent-dark); border-radius: 999px; padding: 0.3rem 0.85rem; font-size: 0.85rem; font-weight: 600;">Alzheimer's Disease and Related Dementias (ADRD)</span>
</div>
<div class="research-cards">
<div class="research-card">
<div class="research-card-img" style="background-image: url('https://images.unsplash.com/photo-1559757175-5700dde675bc?w=600&h=400&fit=crop&q=80'); background-color: var(--accent-darker);">
<div class="research-card-label">Theme 1</div>
</div>
<div class="research-card-body">
<h3>Multimodal Neuroimaging of Cholinergic Degeneration (NbM/Ch4)</h3>
<p>Flagship program characterizing cholinergic basal-forebrain (nucleus basalis of Meynert, Ch4) degeneration across the AD/ADRD and Parkinson's spectrum. My first-author work established PD mild cognitive impairment with MRI evidence of Ch4 degeneration as a novel clinical-imaging subtype; a companion analysis shows that combining T1 Ch4 gray-matter density with basal-forebrain free-water diffusion outperforms either modality alone. I integrate structural, free-water diffusion, and resting-state functional MRI for an integrated structure–microstructure–function characterization.</p>
<div class="theme-keywords">NbM/Ch4 · Free-Water DTI · Structure–Function Integration</div>
</div>
</div>
<div class="research-card">
<div class="research-card-img" style="background-image: url('https://images.unsplash.com/photo-1532187863486-abf9dbad1b69?w=600&h=400&fit=crop&q=80'); background-color: var(--accent-darker);">
<div class="research-card-label">Theme 2</div>
</div>
<div class="research-card-body">
<h3>Data-Driven Disease Subtyping & Progression Modeling</h3>
<p>Subtyping neurodegenerative disease and tracking progression with large-scale longitudinal datasets (PPMI, ADNI, NACC, PDBP). My work characterized 10-year PD progression across clinical, pathological, and data-driven subtypes and produced disease-duration–specific percentiles for prospective identification of the diffuse-malignant subtype at diagnosis, using mixed-effects and joint longitudinal–survival models.</p>
<div class="theme-keywords">Machine Learning · Longitudinal Modeling · Progression Tracking</div>
</div>
</div>
<div class="research-card">
<div class="research-card-img" style="background-image: url('https://images.unsplash.com/photo-1551288049-bebda4e38f71?w=600&h=400&fit=crop&q=80'); background-color: var(--accent-darker);">
<div class="research-card-label">Theme 3</div>
</div>
<div class="research-card-body">
<h3>EEG Biomarkers of Lewy Body Disease</h3>
<p>Developing EEG-based biomarkers of cognitive fluctuations in Lewy body disease, combining resting-state and task-based EEG with NASA's Psychomotor Vigilance Test. The aim is objective, deployable monitoring of fluctuating cognition—and, ultimately, a substrate for adaptive neuromodulation interventions.</p>
<div class="theme-keywords">EEG · Cognitive Fluctuations · Neuromodulation</div>
</div>
</div>
</div>
<h3 class="subsection-title" style="margin-top: 2.5rem;">Future Research Directions</h3>
<p class="research-vision-text" style="margin-bottom: 0;">
My independent research program will build on three converging directions: (1) developing clinically deployable EEG and neuroimaging biomarkers for real-time monitoring of cognitive fluctuations in Lewy body spectrum disorders, with the goal of enabling adaptive neuromodulation interventions; (2) establishing multimodal biomarker panels—combining alpha-synuclein seed amplification, plasma NfL/p-tau, and MRI-based vascular and cholinergic markers—for pathology-driven patient stratification to enrich clinical trials of disease-modifying therapies; and (3) leveraging large-scale longitudinal datasets (PPMI, ADNI, NACC, PDBP) with machine learning to build prognostic models that identify high-risk subtypes at diagnosis, enabling earlier intervention. These efforts are designed to bridge the gap between biomarker discovery and clinical trial design, with a focus on translating precision medicine frameworks into actionable tools for neurologists and trial sponsors.
</p>
</div>
</section>
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<h2>Career</h2>
<p>Academic appointments and education across four countries</p>
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<div class="career-legend-item"><span class="legend-dot appointment"></span> Appointment</div>
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<div class="inst-badge" style="background: #000000;" title="VCU">VCU</div>
<div class="timeline-date">March 2023 – Present</div>
<h3>Postdoctoral Scholar</h3>
<h4>VCU Parkinson's & Movement Disorders Center, Department of Neurology · Richmond, VA</h4>
<ul>
<li>Developed EEG-based biomarkers for cognitive fluctuations in Lewy Body Dementia using NASA's Psychomotor Vigilance Test combined with resting-state and task-based EEG analyses</li>
<li>Conducted large-scale database studies stratifying PD, LBD, and AD patients using machine learning across PPMI, NACC, and PDBP cohorts</li>
<li>Identified a novel PD-MCI subtype with MRI evidence of cholinergic nucleus 4 degeneration</li>
<li>Led studies defining progression patterns across PD subtypes using 10-year longitudinal data</li>
<li>Built comprehensive neuroimaging pipelines for structural, functional, and diffusion MRI analysis</li>
<li>Investigated glymphatic-sleep-cognition-vascular interactions using DTI-ALPS and white matter hyperintensity quantification</li>
<li>Generated pilot data, contributed study design, biostatistical planning, and EEG/neuroimaging methods supporting NIH/NIA R01 application</li>
</ul>
</div>
<div class="timeline-item has-badge">
<div class="inst-badge" style="background: #20558a;" title="NIH">NIH</div>
<div class="timeline-date">August 2025</div>
<h3>IMPACT-AD Fellowship</h3>
<h4>National Institute on Aging (NIA), NIH · San Diego, CA</h4>
<p>Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD. Advanced training in Alzheimer's and related dementias clinical trial design and methodology.</p>
</div>
<div class="timeline-item has-badge">
<div class="inst-badge" style="background: #a51c30;" title="HMS">HMS</div>
<div class="timeline-date">July 2021 – March 2023</div>
<h3>Research Fellow</h3>
<h4>Harvard Medical School, Department of Global Health and Social Medicine · Boston, MA</h4>
<ul>
<li>Assessed global neurological care delivery systems through systematic data collection</li>
<li>Quantified social and environmental determinants of neurological health disparities</li>
<li>Applied external validation methods for financial risk prediction tools in low-income settings</li>
<li>Led the development of CHYSPR guidelines in LMICs (first author, www.chyspr.org)</li>
<li>Produced peer-reviewed outputs informing WHO and regional health policy decisions</li>
</ul>
</div>
<div class="timeline-item has-badge">
<div class="inst-badge" style="background: #5c2d91;" title="UoP">UoP</div>
<div class="timeline-date">May 2022</div>
<h3>Ph.D. in Biomedical Sciences</h3>
<h4>University of Portsmouth · United Kingdom</h4>
<p>Dissertation: "The Hope and the Hype in Parkinson's Disease Treatments" — Meta-research, evidence synthesis, and critical appraisal of neuroprotective interventions.</p>
</div>
<div class="timeline-item has-badge">
<div class="inst-badge" style="background: #0066b3;" title="BAU">BAU</div>
<div class="timeline-date">March – September 2019</div>
<h3>Research Fellow</h3>
<h4>Bahçeşehir University, Department of Neurological Surgery · Istanbul, Turkey</h4>
<ul>
<li>Evaluated deep brain stimulation outcomes in Parkinson's and Huntington's disease patients</li>
<li>Analyzed clinical and neuropsychological endpoints using advanced statistical methods</li>
</ul>
</div>
<div class="timeline-item has-badge">
<div class="inst-badge" style="background: #1a6b3c;" title="ZU">ZU</div>
<div class="timeline-date">December 2018</div>
<h3>M.B.B.Ch. in Medicine and Surgery (equivalent to MD)</h3>
<h4>Zagazig University Faculty of Medicine · Egypt</h4>
</div>
</div>
</div>
</section>
<!-- Grants & Funding -->
<section id="grants" class="fade-in">
<div class="section-inner">
<div class="section-header">
<h2>Grant Contributions</h2>
<p style="font-style: italic;">Contributing role as a postdoctoral scholar.</p>
</div>
<div class="grant-entry">
<div class="grant-status">R01 · Active (2025–2030)</div>
<div class="grant-agency">NIH / National Institute on Aging</div>
<div class="grant-title">"Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia"</div>
<p class="grant-detail"><strong>Role:</strong> Postdoctoral Researcher</p>
<p class="grant-detail"><strong>Contribution:</strong> Generated pilot data, contributed to study design, biostatistical planning, EEG/neuroimaging analysis sections, and grant document preparation.</p>
</div>
<div class="grant-entry">
<div class="grant-status">R21 · Completed (2022–2024)</div>
<div class="grant-agency">NIH / National Institute on Aging</div>
<div class="grant-title">"Development and characterization of EEG signature of cognitive fluctuations in Lewy body dementia"</div>
<p class="grant-detail"><strong>Role:</strong> Postdoctoral Researcher</p>
<p class="grant-detail"><strong>Contribution:</strong> EEG/neuroimaging analysis and manuscript preparation.</p>
</div>
</div>
</section>
<!-- Research Tools & Software -->
<section id="tools" class="fade-in">
<div class="section-inner">
<div class="section-header">
<h2>Research Tools & Software</h2>
<p>Open-source tools developed for clinical neuroscience and evidence synthesis research</p>
</div>
<div class="tool-entry">
<h3>PD-MCI Ch4 Subtyping Tool</h3>
<div class="tool-meta">Parkinsonism & Related Disorders, 2025</div>
<p>Imaging-based subtype tool for PD-MCI using cholinergic nucleus 4 (NBM) gray matter density. Helps identify patients with cholinergic vulnerability markers for treatment selection.</p>
<div class="tool-links-inline">
<a href="https://doi.org/10.1016/j.parkreldis.2025.108072" target="_blank">Paper →</a>
<a href="https://ch4subtyping.negida.com" target="_blank">Online Tool →</a>
</div>
</div>
<div class="tool-entry">
<h3>PD Subtyping Tool</h3>
<div class="tool-meta">Mov Disord Clin Pract, 2026 · npj Parkinson's Disease, 2026</div>
<p>Interactive tool for clinical, pathological, and data-driven subtyping of Parkinson's Disease. Applies disease-duration–specific percentile thresholds (PPMI, N=1,030) to classify patients into diffuse-malignant, intermediate, and mild-motor-predominant subtypes for real-time trial stratification.</p>
<div class="tool-links-inline">
<a href="pd-subtyping.html"><strong>Read the research story →</strong></a>
<a href="https://negidamd.github.io/data-driven-pd-subtype-calculator/" target="_blank">Percentile Calculator →</a>
<a href="https://pdsubtyping.negida.com" target="_blank">Online Tool →</a>
<a href="https://doi.org/10.1002/mdc3.70740" target="_blank">Percentiles paper →</a>
<a href="https://doi.org/10.1038/s41531-026-01430-8" target="_blank">Milestones paper →</a>
</div>
</div>
<div class="tool-entry">
<h3>Vol-HD</h3>
<div class="tool-meta">Movement Disorders, 2024</div>
<p>Online calculator for predicting striatal volumes in Huntington's Disease patients using demographic and clinical variables, enabling pre-screening for clinical trials of intrastriatal gene therapies.</p>
<div class="tool-links-inline">
<a href="https://doi.org/10.1002/mds.29749" target="_blank">Paper →</a>
<a href="https://concepcion388.softr.app" target="_blank">Online Tool →</a>
</div>
</div>
<div class="tool-entry">
<h3>Meta-Analysis Accelerator</h3>
<div class="tool-meta">BMC Medical Research Methodology, 2024 · 12,000+ Users</div>
<p>Comprehensive statistical conversion tool for systematic reviews with 21 conversion functions including median/IQR to mean/SD, SEM to SD, and CI to SD for one and two groups.</p>
<div class="tool-links-inline">
<a href="https://meta-analysis-accelerator.com" target="_blank">Online Tool →</a>
</div>
</div>
<div class="tool-entry">
<h3>Meta-analysis.io</h3>
<div class="tool-meta">Comprehensive Meta-Analysis Platform</div>
<p>Full-featured platform for meta-analyses with statistical analysis and visualization. Supports standard meta-analysis, DTA, meta-regression, subgroup analysis, and publication bias assessment.</p>