Extracting data for 29302 SNP(s) from 1 GWAS(s) 1 of 1 outcomes [>] 1 of 3 chunks Error in api_query("associations", query = list(variant = variants, id = id, : The query to MR-Base exceeded 300 seconds and timed out. Please simplify the query

[cnblack]

I've been trying to extract outcome data using extract_outcome_data(snps=exposure_dat$SNP, outcomes=outcomeID) from this package, but I keep getting an error: Error in api_query("associations", query = list(variant = variants, id = id, : The query to MR-Base exceeded 300 seconds and timed out. Please simplify the query. It's been like this for three days now. How can I fix it?

[Noralii]

I also met the same problem

[remlapmot]

That's alot of SNPs.

You need to update your TwoSampleMR and ieugwasr packages - you can use the following command to do this.

install.packages("TwoSampleMR", repos = c("https://mrcieu.r-universe.dev", "https://cran.r-project.org"))

Then you need to obtain an OPENGWAS_JWT token - see the ieugwasr documentation https://mrcieu.github.io/ieugwasr/articles/guide.html - and store it in your .Renviron file - then restart R.

[DRleifeng]

So did I. May I ask how it has since been resolved?

[shiqi-shan]

Extracting data for 0 SNP(s) from 1 GWAS(s)