mechanogenomic-virtual-cell/CITATION.cff at main · Danpc11/mechanogenomic-virtual-cell · GitHub

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cff-version: 1.2.0
message: "If you use this software, please cite it as below."
title: "Mechanogenomic virtual-cell model"
abstract: >-
  A minimal, first-principles physical model of nuclear mechanotransduction
  linking substrate stiffness to nuclear deformation, YAP/TAZ activity, and
  fibrosis-associated transcriptional trajectories. Calibrated against nuclear
  area of primary hepatocytes on hydrogels and validated against human liver
  RNA-seq cohorts across fibrosis stages.
type: software
authors:
  - family-names: "Pérez-Calixto"
    given-names: "Daniel"
    affiliation: "Instituto Nacional de Medicina Genómica (INMEGEN)"
  - family-names: "Tovar-Romero"
    given-names: "Hugo Antonio"
    affiliation: "Instituto Nacional de Medicina Genómica (INMEGEN)"
  - family-names: "Vázquez-Victorio"
    given-names: "Genaro"
    affiliation: "Facultad de Ciencias, Universidad Nacional Autónoma de México (FC/UNAM)"
repository-code: "https://github.com/Danpc11/mechanogenomic-virtual-cell"
license: MIT
keywords:
  - biophysics
  - mechanobiology
  - mechanotransduction
  - cell-nucleus
  - virtual-cell-models
  - motor-clutch
  - hepatic-fibrosis
  - YAP-TAZ
version: "0.1.0"
date-released: "2026-07-01"