The Bioconductor TAB has discussed this quite a bit. But I am interested in discussing with whomever is interested.
The Matrix package is very useful for dealing with sparse single cell and spatial tx data. But once you have more than 2^31 non zeros in your data matrix, you can no longer use this package due to R's limit on longest vector. Hervé Pagès' SparseArray deals with this but it does not have all the functionality Matrix has.
The Bioconductor TAB has discussed this quite a bit. But I am interested in discussing with whomever is interested.
The Matrix package is very useful for dealing with sparse single cell and spatial tx data. But once you have more than 2^31 non zeros in your data matrix, you can no longer use this package due to R's limit on longest vector. Hervé Pagès' SparseArray deals with this but it does not have all the functionality Matrix has.