diff --git a/src/apps/cn.dxy.medicinehelper.ts b/src/apps/cn.dxy.medicinehelper.ts
new file mode 100644
index 000000000..8ec7033a8
--- /dev/null
+++ b/src/apps/cn.dxy.medicinehelper.ts
@@ -0,0 +1,100 @@
+import { defineGkdApp } from '@gkd-kit/define';
+
+export default defineGkdApp({
+  id: 'cn.dxy.medicinehelper',
+  name: '用药助手',
+  groups: [
+    {
+      key: 1,
+      name: '更新提示',
+      rules: [
+        {
+          fastQuery: true,
+          activityIds: 'cn.dxy.medicinehelper.activity.MainComposeActivity',
+          matches: '[vid="blankForClose"] + [vid="iv_close"]',
+        },
+      ],
+    },
+    {
+      key: 2,
+      name: '分段广告',
+      rules: [
+        {
+          key: 0,
+          activityIds:
+            'cn.dxy.medicinehelper.article.dailylearn.DailyLearnComposeActivity',
+          matches: '[text="去学习"] + [text^="+"][text$="丁当"]',
+          snapshotUrls: 'https://i.gkd.li/i/25246837',
+        },
+        {
+          preKeys: [0],
+          key: 1,
+          action: 'back',
+        },
+      ],
+    },
+    {
+      key: 3,
+      name: '局部广告',
+      rules: [
+        {
+          key: 0,
+          activityIds: [
+            '.article.dailylearn.DailyLearnComposeActivity',
+            'cn.dxy.drugscomm.business.ebm.EbmContentComposeActivity',
+            'cn.dxy.drugscomm.business.drug.detail.DrugDetailComposeActivity',
+          ],
+          matches: ['[text="展开"][visibleToUser=true]'],
+          snapshotUrls: [
+            'https://i.gkd.li/i/25246982', //展开完整信息
+            'https://i.gkd.li/i/25247361',
+            'https://i.gkd.li/i/25247525',
+          ],
+        },
+      ],
+    },
+    {
+      key: 4,
+      name: '功能类-药品说明书-表格全屏自动横屏观看',
+      rules: [
+        {
+          key: 0,
+          activityIds:
+            'cn.dxy.drugscomm.business.drug.detail.DrugDetailComposeActivity',
+          matches: '@TextView[text="横屏"]',
+          snapshotUrls: 'https://i.gkd.li/i/25247591',
+        },
+      ],
+    },
+    {
+      key: 5,
+      name: '全屏广告',
+      rules: [
+        {
+          key: 0,
+          activityIds:
+            'cn.dxy.drugscomm.business.medadviser.detail.MedAdviserDetailComposeActivity',
+          matches:
+            '[text*="有帮助吗"] + [text*="参与反馈"] +n ImageView[clickable=true][width<100 && height<100]',
+          snapshotUrls: 'https://i.gkd.li/i/25247634',
+        },
+        {
+          key: 1,
+          activityIds:
+            'cn.dxy.drugscomm.business.ebm.EbmContentComposeActivity',
+          matches:
+            '@ImageView[clickable=true][visibleToUser=true][width<102 && height<102] - View < View[childCount=2]',
+          snapshotUrls: 'https://i.gkd.li/i/25247624',
+        },
+        {
+          key: 2,
+          activityIds:
+            'cn.dxy.drugscomm.business.guide.detail.GuideDetailComposeActivity',
+          matches:
+            '@ImageView[desc="用药助手"][clickable=true][visibleToUser=true][width<102 && height<102] - ImageView < View[childCount=5]',
+          snapshotUrls: 'https://i.gkd.li/i/25247659',
+        },
+      ],
+    },
+  ],
+});